Dr Mohanraj Sadasivam, PhD - Johns Hopkins University - Post doctoral fellow

Dr Mohanraj Sadasivam

PhD

Johns Hopkins University

Post doctoral fellow

Baltimore, MD | United States

Main Specialties: Nephrology, Pathology-Anatomic & Clinical

Additional Specialties: Immunology, Nephrology

ORCID logohttps://orcid.org/0000-0002-3132-2948


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Dr Mohanraj Sadasivam, PhD - Johns Hopkins University - Post doctoral fellow

Dr Mohanraj Sadasivam

PhD

Introduction

Dr. Mohanraj Sadasivam, Ph.D. is currently a post-doctoral research fellow with the Department of Pathology at Johns Hopkins University. He received his Ph.D. in Biochemistry from Bharathidasan University in Tiruchirappalli, India where he studied cytokine-mediated Histone H3 modification in Leydig cells and its implication in the regulation of testicular steroidogenesis. His current research focuses on a neglected T cell subset (Double negative T cells) and its role in kidney injury. His studies include trying to understand their origin and physiological functions in the kidney, which thus far suggest a critical role in protecting the kidneys from Ischemia Reperfusion Injury (IRI).

Primary Affiliation: Johns Hopkins University - Baltimore, MD , United States

Specialties:

Additional Specialties:

Research Interests:

Education

Apr 2015
Bharathidasan University
Ph.D. Biochemistry
Apr 2008
Dr. A. L. M PG IBMS, University of Madras
M.Sc. Medical Biochemistry
Apr 2006
St. Joseph’s college of arts and science
B.Sc. Biochemistry

Experience

Mar 2016
Johns Hopkins University
Post-Doc
Pathology

Publications

13Publications

311Reads

32Profile Views

16PubMed Central Citations

Characterization of kidney CD45intCD11bintF4/80+MHCII+CX3CR1+Ly6C- "intermediate mononuclear phagocytic cells".

PLoS One 2018 1;13(6):e0198608. Epub 2018 Jun 1.

Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198608PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983557PMC
January 2019
15 Reads
2 Citations
3.234 Impact Factor

Unexpected alliance between syndecan-1 and innate-like T cells to protect host from autoimmune effects of interleukin-17.

World J Diabetes 2018 Dec;9(12):220-225

Department of Pathology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, United States.

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http://www.wjgnet.com/1948-9358/full/v9/i12/220.htm
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http://dx.doi.org/10.4239/wjd.v9.i12.220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304294PMC
December 2018
33 Reads

Syndecan-1 Regulates Psoriasiform Dermatitis by Controlling Homeostasis of IL-17-Producing γδ T Cells.

J Immunol 2018 09 25;201(6):1651-1661. Epub 2018 Jul 25.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205;

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http://dx.doi.org/10.4049/jimmunol.1800104DOI Listing
September 2018
4 Reads
4.922 Impact Factor

Editing Using CRISPR/Cas9 for Therapeutic NRF2 Activation in Primary Human T Lymphocytes.

J Immunol 2018 03 19;200(5):1929-1936. Epub 2018 Jan 19.

Division of Nephrology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21205; and

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http://dx.doi.org/10.4049/jimmunol.1700812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821541PMC
March 2018
6 Reads
4.922 Impact Factor

Syndecan-1-coating of interleukin-17-producing natural killer T cells provides a specific method for their visualization and analysis.

World J Diabetes 2017 Apr;8(4):130-134

Anil Kumar Jaiswal, Mohanraj Sadasivam, Abdel Rahim A Hamad, Department of Pathology, Johns Hopkins University, School of Medicine, Baltimore, MD 21205, United States.

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http://dx.doi.org/10.4239/wjd.v8.i4.130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394732PMC
April 2017
13 Reads

Sirtuin 4 Regulates Lipopolysaccharide Mediated Leydig Cell Dysfunction.

J Cell Biochem 2016 Apr 22;117(4):904-16. Epub 2015 Sep 22.

Department of Biochemistry, Bharathidasan University, Tiruchirappalli, India.

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http://dx.doi.org/10.1002/jcb.25374DOI Listing
April 2016
7 Reads
2 Citations
3.263 Impact Factor

HDAC7 modulates TNF-α-mediated suppression of Leydig cell steroidogenesis.

Mol Cell Biochem 2015 Aug 28;406(1-2):83-90. Epub 2015 Apr 28.

Department of Biochemistry, Bharathidasan University, Tiruchirappalli, 620 024, India.

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http://dx.doi.org/10.1007/s11010-015-2426-yDOI Listing
August 2015
4 Reads
2.393 Impact Factor

TNF-α-mediated suppression of Leydig cell steroidogenesis involves DAX-1.

Inflamm Res 2015 Jul 6;64(7):549-56. Epub 2015 Jun 6.

Department of Biochemistry, Bharathidasan University, Tiruchirappalli, 620 024, India.

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http://dx.doi.org/10.1007/s00011-015-0835-8DOI Listing
July 2015
34 Reads
2 Citations
2.143 Impact Factor

The role of phosphoenolpyruvate carboxykinase in neuronal steroidogenesis under acute inflammation.

Gene 2014 Dec 23;552(2):249-54. Epub 2014 Sep 23.

Department of Biochemistry, Bharathidasan University, Tiruchirappalli 620 024, India. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2014.09.043DOI Listing
December 2014
11 Reads
3 Citations
2.140 Impact Factor

Glucose modulates Pax6 expression through the JNK/p38 MAP kinase pathway in pancreatic beta-cells.

Life Sci 2014 Jul 20;109(1):1-7. Epub 2014 Jun 20.

Department of Biochemistry, Bharathidasan University, Tiruchirappalli 620 024, India. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2014.06.009DOI Listing
July 2014
6 Reads
3 Citations
2.702 Impact Factor

Bacterial lipopolysaccharide differently modulates steroidogenic enzymes gene expressions in the brain and testis in rats.

Neurosci Res 2014 Jun 1;83:81-8. Epub 2014 Mar 1.

Department of Biochemistry, Bharathidasan University, Tiruchirappalli 620 024, India. Electronic address:

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http://dx.doi.org/10.1016/j.neures.2014.02.011DOI Listing
June 2014
5 Reads
4 Citations
1.940 Impact Factor

Top co-authors

Chidambaram Prahalathan
Chidambaram Prahalathan

University of Madras

6
Balamurugan Ramatchandirin
Balamurugan Ramatchandirin

Bharathidasan University

5
Sul A Lee
Sul A Lee

Yonsei University

4
Hamid Rabb
Hamid Rabb

Johns Hopkins University School of Medicine

4
Sanjeev Noel
Sanjeev Noel

Central Drug Research Institute

4
Sivasangari Balakrishnan
Sivasangari Balakrishnan

Bharathidasan University

4
Anil Kumar Jaiswal
Anil Kumar Jaiswal

Central Drug Research Institute

3
Arun Kannan
Arun Kannan

Cornell University

2
Mohamad E Allaf
Mohamad E Allaf

James Buchanan Brady Urological Institute

2