Publications by authors named "Mohanish Deshmukh"

44Publications

p53 is required for nuclear but not mitochondrial DNA damage-induced degeneration.

Cell Death Dis 2021 Jan 20;12(1):104. Epub 2021 Jan 20.

Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, 27599, USA.

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January 2021

Characterization of a Cul9-Parkin double knockout mouse model for Parkinson's disease.

Sci Rep 2020 10 9;10(1):16886. Epub 2020 Oct 9.

Neuroscience Center, University of North Carolina, Chapel Hill, NC, USA.

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October 2020

Apoptotic cell death regulation in neurons.

FEBS J 2019 09 12;286(17):3276-3298. Epub 2019 Jul 12.

Neuroscience Center, UNC Chapel Hill, NC, USA.

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September 2019

Apoptosis versus axon pruning: Molecular intersection of two distinct pathways for axon degeneration.

Neurosci Res 2019 Feb 16;139:3-8. Epub 2018 Nov 16.

Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, 27599, USA; Neuroscience Center, University of North Carolina, Chapel Hill, NC, 27599, USA. Electronic address:

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February 2019

Large SOD1 aggregates, unlike trimeric SOD1, do not impact cell viability in a model of amyotrophic lateral sclerosis.

Proc Natl Acad Sci U S A 2018 05 16;115(18):4661-4665. Epub 2018 Apr 16.

Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599;

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May 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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March 2018

Physiological functions of non-apoptotic caspase activity in the nervous system.

Semin Cell Dev Biol 2018 10 7;82:127-136. Epub 2017 Dec 7.

Neuroscience Center, UNC Chapel Hill, Chapel Hill, NC, USA; Department of Cell Biology and Physiology, UNC Chapel Hill, Chapel Hill, NC, USA. Electronic address:

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October 2018

The paradox of dicer in cancer.

Mol Cell Oncol 2016 May 26;3(3):e1155006. Epub 2016 Feb 26.

Neuroscience Center, University of North Carolina at Chapel Hill , North Carolina.

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May 2016

Axon degeneration: context defines distinct pathways.

Curr Opin Neurobiol 2016 08 16;39:108-15. Epub 2016 May 16.

Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC 27599, USA; Neuroscience Center, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address:

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August 2016

Bcl-xL Is Essential for the Survival and Function of Differentiated Neurons in the Cortex That Control Complex Behaviors.

J Neurosci 2016 05;36(20):5448-61

Neuroscience Center, Neurobiology Curriculum, Carolina Institute for Developmental Disabilities, Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, North Carolina 27599

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May 2016

Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum.

Cell Rep 2016 Jan 31;14(2):216-24. Epub 2015 Dec 31.

Neuroscience Center, University of North Carolina, Chapel Hill, NC 27599, USA; Neurobiology Curriculum, University of North Carolina, Chapel Hill, NC 27599, USA; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address:

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January 2016

Nonnative SOD1 trimer is toxic to motor neurons in a model of amyotrophic lateral sclerosis.

Proc Natl Acad Sci U S A 2016 Jan 30;113(3):614-9. Epub 2015 Dec 30.

Curriculum in Bioinformatics and Computational Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599; Program in Molecular and Cellular Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599;

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January 2016

Neuronal Stress Pathway Mediating a Histone Methyl/Phospho Switch Is Required for Herpes Simplex Virus Reactivation.

Cell Host Microbe 2015 Dec;18(6):649-58

Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address:

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December 2015

Life after MOMP.

Mol Cell 2015 Apr;58(2):199-201

Neuroscience Center, University of North Carolina, Chapel Hill, NC 27599, USA; Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC 27599, USA. Electronic address:

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April 2015

The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells.

Sci Signal 2014 Jul 15;7(334):ra67. Epub 2014 Jul 15.

Neuroscience Center, University of North Carolina, Chapel Hill, NC 27599, USA. Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC 27599, USA. Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA.

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July 2014

Adaptations of energy metabolism during cerebellar neurogenesis are co-opted in medulloblastoma.

Cancer Lett 2015 Jan 22;356(2 Pt A):268-72. Epub 2014 Feb 22.

Neuroscience Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA; Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC, USA; Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC, USA. Electronic address:

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January 2015

Cerebellar granule neuron progenitors are the source of Hk2 in the postnatal cerebellum.

Cancer Metab 2013 Jun 11;1(1):15. Epub 2013 Jun 11.

Department of Neurology, University of North Carolina, Chapel Hill, NC 27599, USA.

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June 2013