Dr Mohammed M Ghoneim, PhD - University of Mississippi - Assistant Professor

Dr Mohammed M Ghoneim

PhD

University of Mississippi

Assistant Professor

Oxford, MS | United States

Additional Specialties: Pharmacognosy


Top Author

Dr Mohammed M Ghoneim, PhD - University of Mississippi - Assistant Professor

Dr Mohammed M Ghoneim

PhD

Introduction

Primary Affiliation: University of Mississippi - Oxford, MS , United States

Additional Specialties:

Metrics

Number of Publications

6

Publications

Number of Profile Views

595

Profile Views

Number of Article Reads

57

Reads

Number of Citations

12

Citations

Education

Oct 2017
Almaarefa colleges, Pharmacy
Acting Head of Pharmacy College
Oct 2015
Almaarefa colleges, Pharmacy
Assistant Professor

Experience

Jan 2018
Visiting scholarship from Egyptian Embassy, USA

Publications

6Publications

57Reads

12PubMed Central Citations

Synthesis and Anticancer Studies of Novel N-Benzyl pyridazinone Derivatives

10.2174/1570180814666170223111312

Letters in Drug Design & Discovery

Introduction: According to WHO, cancer is one of the most leading causes of death. Development of anticancer drugs draw considerable attention. Pyridazinones analogues were reported to possess anticancer properties. Chemical modification of pyridazinone may lead to potential anticancer agent. Objective: The objective of this article is to develop new pyridazinone deriatives and evaluate their anticancer activities. Results: The target compounds were synthesized using Palladium cross coupling reactions, Buchwald and Suzuki, the synthesized compound were evaluated against BT-549, KB and SK-MEL cell lines. Some compounds showed moderate to significant inhibitory activity. Conclusion: Novel pyridazinone derivatives were synthesized in a good yield. Some of the synthesized analogues showed good anticancer properties against BT-549, KB and SK-MEL cell lines.

View Article
February 2017
4 Reads

Antiurease activity of plants growing in the Czech Republic.

Nat Prod Res 2014 28;28(12):868-73. Epub 2014 Feb 28.

a Department of Natural Drugs , Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno , Palackého 1-3, 612 42 Brno , Czech Republic.

View Article
October 2014
10 Reads
1 Citation
0.920 Impact Factor

Asphodosides A-E, anti-MRSA metabolites from Asphodelus microcarpus.

Phytochemistry 2014 Sep 14;105:79-84. Epub 2014 Jul 14.

National Center for Natural Products Research, The University of Mississippi, University, MS 38677, USA; Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, MS 38677, USA. Electronic address:

View Article
September 2014
19 Reads
3 Citations
2.550 Impact Factor

Isolation and characterization of new secondary metabolites from .

Med Chem Res 2014 Jul 11;23(7):3510-3515. Epub 2014 Feb 11.

Department of Pharmacognosy and National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University, MS 38677, USA.

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July 2014
18 Reads
1 Citation

Zeaoxazolinone, a new antifungal agent frombZea mays roots

Medicinal Chemistry Research

A new 7-methoxy-2-benzoxazolinone dimer named zeaoxazolinone (2), together with four known compounds; 9-Z-hexadecenoic acid (1), 6-methoxy-benzoxazolinone (3), gallic acid (4), andb-sitosterol-3-O-b-D-glucopyranoside (5) were isolated fromZea maysL. roots. The structural elucidation of isolated metabolites was established on the basis of UV, IR, 1D, 2D NMR, and MS spectral analyses. Compound 2 exhibited a potent antifungal activity againstAspergillus flavus,Fusarium oxysporum,andCandida albicans.

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May 2014
10 Reads

Biologically active secondary metabolites from Asphodelus microcarpus.

Nat Prod Commun 2013 Aug;8(8):1117-9

National Center for Natural Products Research School of Pharmacy, The University of Mississippi, University, MS 38677, USA.

View Article
August 2013
10 Reads
7 Citations