Publications by authors named "Mohammed Alshalalfa"

68Publications

Doublecortin Expression in Prostate Adenocarcinoma and Neuroendocrine Tumors.

Int J Radiat Oncol Biol Phys 2020 Nov 22;108(4):936-940. Epub 2020 Jun 22.

Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts.

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November 2020

Epigenetic analysis identifies factors driving racial disparity in prostate cancer.

Cancer Rep (Hoboken) 2019 Apr 13;2(2):e1153. Epub 2018 Dec 13.

Department of Urology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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April 2019

Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer.

EBioMedicine 2018 May 23;31:182-189. Epub 2018 Apr 23.

Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, Manchester M20 4BX, UK; NIHR Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, UK. Electronic address:

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May 2018

Validation of a 10-gene molecular signature for predicting biochemical recurrence and clinical metastasis in localized prostate cancer.

J Cancer Res Clin Oncol 2018 May 6;144(5):883-891. Epub 2018 Mar 6.

Department of Pathology and Laboratory Medicine, University of Calgary, Cumming School of Medicine, Calgary, AB, Canada.

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May 2018

Clinical and Genomic Characterization of Low-Prostate-specific Antigen, High-grade Prostate Cancer.

Eur Urol 2018 08 22;74(2):146-154. Epub 2018 Feb 22.

Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address:

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August 2018

Gene expression signatures of neuroendocrine prostate cancer and primary small cell prostatic carcinoma.

BMC Cancer 2017 Nov 13;17(1):759. Epub 2017 Nov 13.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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November 2017

Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer.

Cell Rep 2017 06;19(10):2045-2059

Centre for Molecular Medicine Norway, Nordic European Molecular Biology Laboratory Partnership, Forskningsparken, University of Oslo, 21 0349 Oslo, Norway; Department of Molecular Oncology, Institute for Cancer Research, Oslo University Hospital, 0424 Oslo, Norway; PCUK Movember Centre of Excellence, CCRCB, Queen's University, Belfast BT7 1NN, Northern Ireland, UK. Electronic address:

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June 2017

Comprehensive Determination of Prostate Tumor ETS Gene Status in Clinical Samples Using the CLIA Decipher Assay.

J Mol Diagn 2017 05 21;19(3):475-484. Epub 2017 Mar 21.

Department of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland. Electronic address:

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May 2017

Multi-institutional Analysis Shows that Low PCAT-14 Expression Associates with Poor Outcomes in Prostate Cancer.

Eur Urol 2017 02 22;71(2):257-266. Epub 2016 Jul 22.

Department of Internal Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA; Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO, USA; Beaumont Hospital-Dearborn, Transitional Year Program, Dearborn, MI, USA; Department of Biomedical Engineering, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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February 2017

High alpha-methylacyl-CoA racemase (AMACR) is associated with ERG expression and with adverse clinical outcome in patients with localized prostate cancer.

Tumour Biol 2016 Sep 7;37(9):12287-12299. Epub 2016 Jun 7.

Department of Pathology and Laboratory Medicine, University of Calgary and Calgary Laboratory Services, Calgary, Alberta, Canada.

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September 2016

Development and validation of a 24-gene predictor of response to postoperative radiotherapy in prostate cancer: a matched, retrospective analysis.

Lancet Oncol 2016 Nov 12;17(11):1612-1620. Epub 2016 Oct 12.

Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA; Michigan Center for Translational Pathology, Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI, USA; Department of Radiation Oncology, University of California at San Francisco, San Francisco, CA, USA; Department of Medicine, University of California at San Francisco, San Francisco, CA, USA; Helen Diller Comprehensive Cancer Center, University of California at San Francisco, San Francisco, CA, USA. Electronic address:

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November 2016

Ankyrin G expression is associated with androgen receptor stability, invasiveness, and lethal outcome in prostate cancer patients.

J Mol Med (Berl) 2016 12 18;94(12):1411-1422. Epub 2016 Aug 18.

Department of Pathology and Laboratory Medicine, University of Calgary, Calgary Laboratory Services, Calgary, Canada.

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December 2016

Integrated Classification of Prostate Cancer Reveals a Novel Luminal Subtype with Poor Outcome.

Cancer Res 2016 09 14;76(17):4948-58. Epub 2016 Jun 14.

Division of Cancer Biology and Therapeutics, Departments of Surgery & Biomedical Sciences, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.

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September 2016

Application of a Clinical Whole-Transcriptome Assay for Staging and Prognosis of Prostate Cancer Diagnosed in Needle Core Biopsy Specimens.

J Mol Diagn 2016 05 3;18(3):395-406. Epub 2016 Mar 3.

Department of Urology, University of California San Francisco, San Francisco, California; Department of Anatomic Pathology, University of California San Francisco, San Francisco, California.

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May 2016

ING3 is associated with increased cell invasion and lethal outcome in ERG-negative prostate cancer patients.

Tumour Biol 2016 Jul 23;37(7):9731-8. Epub 2016 Jan 23.

Department of Pathology and Laboratory Medicine, University of Calgary and Calgary Laboratory Services, Calgary, Alberta, Canada.

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July 2016

Characterization of 1577 primary prostate cancers reveals novel biological and clinicopathologic insights into molecular subtypes.

Eur Urol 2015 Oct 8;68(4):555-67. Epub 2015 May 8.

Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI, USA; Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address:

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October 2015

Discovery and validation of novel expression signature for postcystectomy recurrence in high-risk bladder cancer.

J Natl Cancer Inst 2014 Nov 24;106(11). Epub 2014 Oct 24.

Department of Pathology and Center for Personalized Medicine (APM, TJT) and Institute of Urology and Norris Comprehensive Cancer Center (SD), University of Southern California, Los Angeles, CA; GenomeDx Biosciences, Inc., Vancouver, BC (LLL, MG, NE, IAV, MA, CB, ZH, TS, TJT, ED); Department of Urology and the Stanford Cancer Institute, Stanford University, Stanford, CA (ECS); Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia, Canada (PCB).

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November 2014

The prognostic significance of combined ERG and androgen receptor expression in patients with prostate cancer managed by androgen deprivation therapy.

Cancer Biol Ther 2014 Sep 27;15(9):1120-8. Epub 2014 Jun 27.

Department of Pathology and Laboratory Medicine; University of Calgary and Calgary Laboratory Services; Calgary, AB Canada; Departments of Oncology, Biochemistry and Molecular Biology; Calgary, AB Canada; Southern Alberta Cancer Institute and Tom Baker Cancer Center; Calgary, AB Canada; The Prostate Cancer Center; Calgary, AB Canada.

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September 2014

Cysteine- rich secretory protein 3 (CRISP3), ERG and PTEN define a molecular subtype of prostate cancer with implication to patients' prognosis.

J Hematol Oncol 2014 Mar 7;7:21. Epub 2014 Mar 7.

Department of Pathology and Laboratory Medicine, University of Calgary and Calgary Laboratory Services, Calgary, AB, Canada.

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March 2014

miRNA regulation in the context of functional protein networks: principles and applications.

Wiley Interdiscip Rev Syst Biol Med 2014 Mar-Apr;6(2):189-99. Epub 2013 Nov 8.

Department of Computer Science, University of Calgary, Calgary, Alberta, Canada.

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October 2014

Prediction of novel drug indications using network driven biological data prioritization and integration.

J Cheminform 2014 Jan 7;6(1). Epub 2014 Jan 7.

Department of Computer Science, University of Calgary, Calgary, Alberta, Canada.

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January 2014

Coordinate microRNA-mediated regulation of protein complexes in prostate cancer.

PLoS One 2013 31;8(12):e84261. Epub 2013 Dec 31.

Department of Computer Science, University of Calgary, Calgary, Alberta, Canada.

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September 2014

Interrogation of ERG gene rearrangements in prostate cancer identifies a prognostic 10-gene signature with relevant implication to patients' clinical outcome.

BJU Int 2014 Feb 5;113(2):309-19. Epub 2013 Sep 5.

Department of Pathology and Laboratory Medicine, University of Calgary and Calgary Laboratory Services, Calgary, AB, Canada; Department of Oncology, University of Calgary, Calgary, AB, Canada; Southern Alberta Cancer Institute and Tom Baker Cancer Center, Calgary, AB, Canada.

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February 2014

Protein network-based Lasso regression model for the construction of disease-miRNA functional interactions.

EURASIP J Bioinform Syst Biol 2013 Jan 22;2013(1). Epub 2013 Jan 22.

Department of Computer Science, University of Calgary, Calgary, Alberta, Canada.

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January 2013

MicroRNA Response Elements-Mediated miRNA-miRNA Interactions in Prostate Cancer.

Adv Bioinformatics 2012 4;2012:839837. Epub 2012 Nov 4.

Department of Computer Science, University of Calgary, 2500 University Dr. NW, Calgary, AB, Canada T2N 1N4 ; Biotechnology Research Center, Palestine Polytechnic University, Hebron, Palestine.

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November 2012

Detecting microRNAs of high influence on protein functional interaction networks: a prostate cancer case study.

BMC Syst Biol 2012 Aug 28;6:112. Epub 2012 Aug 28.

Department of Computer Science, University of Calgary, Calgary, AB, Canada.

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August 2012

Detecting cancer outlier genes with potential rearrangement using gene expression data and biological networks.

Adv Bioinformatics 2012 28;2012:373506. Epub 2012 Jun 28.

Department of Computer Science, University of Calgary, Calgary, AB, Canada T2N 1N4.

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August 2012

Combining multiple perspective as intelligent agents into robust approach for biomarker detection in gene expression data.

Int J Data Min Bioinform 2011 ;5(3):332-50

Department of Computer Science, University of Calgary, Calgary, Alberta, Canada.

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September 2011

Influence of prior knowledge in constraint-based learning of gene regulatory networks.

IEEE/ACM Trans Comput Biol Bioinform 2011 Jan-Mar;8(1):130-42

Department of Computer Engineering, TOBB University of Economics and Technology, Ankara, Turkey.

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February 2011

Adaptive machine learning technique for periodicity detection in biological sequences.

Int J Neural Syst 2009 Feb;19(1):11-24

Department of Computer Science, University of Calgary, Calgary, Canada.

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February 2009