Associate Professor Mohammed A Alshawsh, PhD - University of Malaya - Associate Professor

Associate Professor Mohammed A Alshawsh

PhD

University of Malaya

Associate Professor

Kuala Lumpur | Malaysia

ORCID logohttps://orcid.org/0000-0001-8342-5183

Associate Professor Mohammed A Alshawsh, PhD - University of Malaya - Associate Professor

Associate Professor Mohammed A Alshawsh

PhD

Introduction

Dr. Mohammed Alshawsh is currently working as Associate Professor at Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. He obtained his PhD from Faculty of Medicine, University of Malaya in 2012. After his one year postdoc at University of Malaya, he joined Department of Pharmacology, University of Malaya in 2013. Since then he has been doing preclinical research in the area of metabolic syndrome, cancer and safety pharmacology. His current field of research interest mainly focuses on pharmacological and toxicological evaluation of natural products for the treatment of colorectal cancer, obesity, diabetes, and fatty liver diseases using in vivo (animal models) and in vitro (cell culture) studies and investigating the gene expression profiling to unravel the underlying molecular mechanisms involved. He is also doing safety and toxicology studies in particular acute, subacute, and chronic toxicities, genotoxicity, teratogenicity and postnatal developmental toxicity. Dr. Alshawsh is a scientist member of Faculty of Medicine-Institutional Animal Care and Use Committee (FOM-IACUC)-University Malaya, Italo-Latin American Society of Ethnomedicine, Laboratory Animal Science Association of Malaysia (LASAM), and Malaysian Society of Pharmacology and Physiology. He serves as Associate Editor for the BMC Complementary and Alternative Medicine Journal. He is also an editorial board member and a reviewer for several international journals. He supervised 3 PhD students to completion; currently, he is supervising 7 PhD students and 1 Master student. He has published over 40 papers in peer-reviewed journals and has given over 20 invited and plenary lectures at international conferences. He has obtained several research grants, such as UMRG, PPP and FRGS and has an h-index of 11 and citations of more than 336 (Scopus)

Primary Affiliation: University of Malaya - Kuala Lumpur , Malaysia

Education

Jul 2009 - Feb 2013
University of Malaya
PhD/ Immunology
Molecular Medicine

Experience

Oct 2013
University of Malaya
Associate Professor
Pharmacology

Publications

73Publications

496Reads

90Profile Views

106PubMed Central Citations

Potential toxicity effects of Anastatica hierochuntica aqueous extract on prenatal development of Sprague-Dawley rats.

J Ethnopharmacol 2019 Dec 22;245:112180. Epub 2019 Aug 22.

Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1016/j.jep.2019.112180DOI Listing
December 2019
7 Reads
2.998 Impact Factor

Antiproliferative and apoptotic activities of 8-prenylnaringenin against human colon cancer cells.

Life Sci 2019 Sep 3;232:116633. Epub 2019 Jul 3.

Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address:

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http://dx.doi.org/10.1016/j.lfs.2019.116633DOI Listing
September 2019
2 Reads
2.702 Impact Factor

Evaluating the oestrogenic activities of aqueous root extract of Lam in female Sprague-Dawley rats and its phytochemical screening using Gas Chromatography-Mass Spectrometry (GC/MS).

PeerJ 2019 19;7:e7254. Epub 2019 Jul 19.

University of Malaya Bioequivalence Testing Centre (UBAT), Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Selangor, Malaysia.

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http://dx.doi.org/10.7717/peerj.7254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644626PMC
July 2019
1 Read

Evaluation of Anti-Tumorigenic Effects of Diosmetin against Human Colon Cancer Xenografts in Athymic Nude Mice.

Molecules 2019 Jul 10;24(14). Epub 2019 Jul 10.

Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.

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http://dx.doi.org/10.3390/molecules24142522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6680397PMC
July 2019
2 Reads
2.416 Impact Factor

Mutagenicity and genotoxicity effects of Verbena officinalis leaves extract in Sprague-Dawley Rats.

J Ethnopharmacol 2019 May 6;235:88-99. Epub 2019 Feb 6.

Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2019.02.007DOI Listing
May 2019
3 Reads
2.998 Impact Factor

Cynometra cauliflora Linn. Attenuates metabolic abnormalities in high-fat diet-induced obese mice.

J Ethnopharmacol 2019 May 6;236:173-182. Epub 2019 Mar 6.

Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2019.03.001DOI Listing
May 2019
6 Reads
2.998 Impact Factor

Prenatal developmental toxicity evaluation of Verbena officinalis during gestation period in female Sprague-Dawley rats.

Chem Biol Interact 2019 May 23;304:28-42. Epub 2019 Feb 23.

Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2019.02.016DOI Listing
May 2019
25 Reads
2.577 Impact Factor

Investigation into the Molecular Mechanisms underlying the Anti-proliferative and Anti-tumorigenesis activities of Diosmetin against HCT-116 Human Colorectal Cancer.

Sci Rep 2019 03 26;9(1):5148. Epub 2019 Mar 26.

Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1038/s41598-019-41685-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435658PMC
March 2019
80 Reads
5.078 Impact Factor

Effect of Catha edulis (khat) on pancreatic functions in streptozotocin-induced diabetes in male Sprague-Dawley rats.

Exp Anim 2018 Nov 3;67(4):517-526. Epub 2018 Jul 3.

Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1538/expanim.18-0057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219881PMC
November 2018
5 Reads

Mutagenicity evaluation of Anastatica hierochuntica L. aqueous extract in vitro and in vivo.

Exp Biol Med (Maywood) 2018 02 13;243(4):375-385. Epub 2017 Dec 13.

1 Department of Anatomy, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.

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http://dx.doi.org/10.1177/1535370217748574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022925PMC
February 2018
14 Reads

Khat (Catha edulis) and Obesity: A Scoping Review of Animal and Human Studies.

Ann Nutr Metab 2016 22;69(3-4):200-211. Epub 2016 Nov 22.

Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1159/000452895DOI Listing
January 2018
22 Reads
1 Citation
2.620 Impact Factor

Antiobesity and Lipid Lowering Effects of Orthosiphon stamineus in High-Fat Diet-Induced Obese Mice.

Planta Med 2017 May 19;83(8):684-692. Epub 2016 Dec 19.

Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1055/s-0042-121754DOI Listing
May 2017
7 Reads
1 Citation
2.152 Impact Factor

Biological activities of Anastatica hierochuntica L.: A systematic review.

Zin SRM, Kassim NM, Alshawsh MA, Hashim NE, Mohamed Z, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, vol. 91, pp. 611-620, 2017

http://europepmc.org/abstract/med/28486192

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May 2017
6 Reads

Antiobesity and Lipid Lowering Effects of Orthosiphon stamineus in High-Fat Diet-Induced Obese Mice.

Seyedan A, Alshawsh MA, Alshagga MA, Mohamed Z, Planta medica, 2017, vol. 83, no. 8, pp. 684-692, 2017

http://europepmc.org/abstract/med/27992939

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May 2017
12 Reads

An Association Map on the Effect of Flavonoids on the Signaling Pathways in Colorectal Cancer.

Int J Med Sci 2016 29;13(5):374-85. Epub 2016 Apr 29.

Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.7150/ijms.14485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879672PMC
April 2017
5 Reads
6 Citations
2.003 Impact Factor

Chemopreventive effect of Phaleria macrocarpa on colorectal cancer aberrant crypt foci in vivo.

J Ethnopharmacol 2016 Dec 2;193:195-206. Epub 2016 Aug 2.

Department of Biomedical Science, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2016.08.002DOI Listing
December 2016
45 Reads
3.000 Impact Factor

Chemopreventive Effect of Phaleria macrocarpa on Colorectal Cancer Aberrant Crypt Foci In vivo.

Shwter AN, Abdullah NA, Alshawsh MA, El-Seedi HR, Al-Henhena NA, Khalifa SA, Abdulla MA, Journal of ethnopharmacology, 2016, 2016

http://europepmc.org/abstract/med/27492327

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August 2016
8 Reads

Conflicting reports on the role of the glycemic effect of Catha edulis (Khat): A systematic review and meta-analysis.

J Ethnopharmacol 2016 Jun 26;186:30-43. Epub 2016 Mar 26.

Department of Pharmacology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2016.03.045DOI Listing
June 2016
53 Reads
1 Citation
3.000 Impact Factor

An Association Map on the Effect of Flavonoids on the Signaling Pathways in Colorectal Cancer.

Koosha S, Alshawsh MA, Looi CY, Seyedan A, Mohamed Z, International journal of medical sciences, 2016, vol. 13, no. 5, pp. 374-385

http://europepmc.org/abstract/med/27226778

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January 2016
7 Reads

Application of Antrodia camphorata Promotes Rat's Wound Healing In Vivo and Facilitates Fibroblast Cell Proliferation In Vitro.

Evid Based Complement Alternat Med 2015 8;2015:317693. Epub 2015 Oct 8.

Department of Biomedical Science, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1155/2015/317693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617886PMC
November 2015
8 Reads
2 Citations
1.880 Impact Factor

Evaluation of chemopreventive effects of Acanthus ilicifolius against azoxymethane-induced aberrant Crypt Foci in the rat colon.

PLoS One 2014 12;9(5):e96004. Epub 2014 May 12.

Department of Biomedical Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0096004PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018435PMC
January 2015
29 Reads
4 Citations
3.234 Impact Factor

Potential activity of 3-(2-chlorophenyl)-1-phenyl-propenonein accelerating wound healing in rats.

Biomed Res Int 2014 22;2014:792086. Epub 2014 Jan 22.

Department of Biomedical Science, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1155/2014/792086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919117PMC
October 2014
27 Reads
1 Citation

Chemoprevention of colonic aberrant crypt foci by Gynura procumbens in rats.

J Ethnopharmacol 2014 Feb 3;151(3):1194-1201. Epub 2014 Jan 3.

Department of Biomedical Science, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2013.12.044DOI Listing
February 2014
11 Reads
8 Citations
3.000 Impact Factor

Toxicological Features of Catha edulis (Khat) on Livers and Kidneys of Male and Female Sprague-Dawley Rats: A Subchronic Study.

Evid Based Complement Alternat Med 2012 27;2012:829401. Epub 2012 Nov 27.

Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1155/2012/829401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3522130PMC
December 2012
10 Reads
9 Citations
1.880 Impact Factor

Protective Role of Phyllanthus niruri Extract against Thioacetamide-Induced Liver Cirrhosis in Rat Model.

Evid Based Complement Alternat Med 2012 10;2012:241583. Epub 2012 May 10.

Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1155/2012/241583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357973PMC
August 2012
9 Reads
7 Citations
1.880 Impact Factor

Assessment of in vitro antioxidant, antibacterial and immune activation potentials of aqueous and ethanol extracts of Phyllanthus niruri.

J Sci Food Agric 2012 Jul 9;92(9):1874-7. Epub 2012 Jan 9.

Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1002/jsfa.5554DOI Listing
July 2012
6 Reads
5 Citations
1.714 Impact Factor

Free radical scavenging, antimicrobial and immunomodulatory activities of Orthosiphon stamineus.

Molecules 2012 May 8;17(5):5385-95. Epub 2012 May 8.

Department of Molecular Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.

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http://dx.doi.org/10.3390/molecules17055385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268021PMC
May 2012
6 Reads
6 Citations
2.420 Impact Factor

Acute toxicity evaluation, antibacterial, antioxidant and immunomodulatory effects of Melastoma malabathricum.

Molecules 2012 Mar 20;17(3):3547-59. Epub 2012 Mar 20.

Department of Molecular Medicine, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.3390/molecules17033547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6268612PMC
March 2012
6 Reads
2 Citations
2.420 Impact Factor

Antioxidant and gastroprotective activities of Andrographis paniculata (Hempedu Bumi) in Sprague Dawley rats.

Indian J Exp Biol 2011 Oct;49(10):767-72

Department of Biological Science, Faculty of Biosciences and Bioengineering, University of Teknologi Malaysia, 81310, UTM Skudai, Johor, Malaysia.

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October 2011
10 Reads
18 Citations
0.840 Impact Factor

Hepatoprotective Effects of Orthosiphon stamineus Extract on Thioacetamide-Induced Liver Cirrhosis in Rats.

Evid Based Complement Alternat Med 2011 5;2011:103039. Epub 2011 May 5.

Department of Molecular Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur 50603, Malaysia.

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http://dx.doi.org/10.1155/2011/103039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106356PMC
July 2011
4 Reads
18 Citations
1.880 Impact Factor

Assessment of antimalarial activity against Plasmodium falciparum and phytochemical screening of some Yemeni medicinal plants.

Evid Based Complement Alternat Med 2009 Dec 22;6(4):453-6. Epub 2007 Oct 22.

Department of Pharmacognosy, Faculty of Pharmacy, Sana'a-University, Sana'a, Yemen.

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http://dx.doi.org/10.1093/ecam/nem148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781778PMC
December 2009
3 Reads
12 Citations
1.880 Impact Factor

Top co-authors

Zahurin Mohamed
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University of Malaya

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Mahmood A Abdulla
Mahmood A Abdulla

University of Malaya

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Sanaz Koosha
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Hapipah M Ali
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University of Malaya

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Zamri Chik
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