Publications by authors named "Mohammad Farahbakhsh"

4 Publications

  • Page 1 of 1

Neurological features and outcome in COVID-19: dementia can predict severe disease.

J Neurovirol 2021 02 8;27(1):86-93. Epub 2021 Jan 8.

Department of Neurology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

The COVID-19 pandemic has infected more than 22 million people worldwide. Although much has been learned about COVID-19, we do not know much about its neurological features and their outcome. This observational study was conducted on the patients of Imam Hossein Hospital, and 361 adult patients (214 males) with confirmed diagnosis of COVID-19 from March 5, 2020 to April 3, 2020, were enrolled. Data was gathered on age, sex, comorbidities, initial symptoms, symptoms during the disease course, neurological symptoms, and outcome. The mean age of the patients was 61.90 ± 16.76 years. The most common initial symptoms were cough, fever, and dyspnea. In 21 patients (5.8%), the initial symptom was neurological. History of dementia was associated with severe COVID-19 disease (odds ratio = 1.28). During the course of the disease, 186 patients (51.52%) had at least one neurological symptom, the most common being headache (109 [30.2%]), followed by anosmia/ageusia (69, [19.1%]), and dizziness (54, [15%]). Also, 31 patients had neurological complications (8.58%). Anosmia, ageusia, dizziness, and headache were associated with favorable outcome (P < 0.001), while altered mental status and hemiparesis were associated with poor outcome. The mortality rate of patients who had neurological complications was more than twice than that of patients without neurological complication (P = 0.008). Almost half of the patients experienced at least one neurological symptom, which may be the initial presentation of COVID-19. Dementia appears to be associated with severe COVID-19. Mortality was higher in patients with neurological complications, and these patients needed more intensive care.
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http://dx.doi.org/10.1007/s13365-020-00918-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7792552PMC
February 2021

Low-Dose Whole-Lung Irradiation for COVID-19 Pneumonia: Short Course Results.

Int J Radiat Oncol Biol Phys 2020 12 21;108(5):1134-1139. Epub 2020 Jul 21.

Department of Clinical Oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Purpose: The COVID-19 outbreak is affecting people worldwide. Many infected patients have respiratory involvement that may progress to acute respiratory distress syndrome. This pilot study aimed to evaluate the clinical efficacy of low-dose whole-lung radiation therapy in patients with COVID-19 pneumonia.

Methods And Materials: In this clinical trial, conducted in Iran, we enrolled patients with COVID-19 who were older than 60 years and hospitalized to receive supplementary oxygen for their documented pneumonia. Participants were treated with whole-lung irradiation in a single fraction of 0.5 Gy plus the national protocol for the management of COVID-19. Vital signs (including blood oxygenation and body temperature) and laboratory findings (interleukin-6 and C-reactive peptide) were recorded before and after irradiation.

Results: Between May 21, 2020 and June 24, 2020, 5 patients received whole-lung irradiation. They were followed for 5 to 7 days to evaluate the response to treatment and toxicities. The clinical and paraclinical findings of 4 of the 5 patients (patient 4 worsened and died on day 3) improved on the first day of irradiation. Patient 3 opted out of the trial on the third day after irradiation. The mean time to discharge was 6 days for the other 3 patients. No acute radiation-induced toxicity was recorded.

Conclusions: With a response rate of 80%, whole-lung irradiation in a single fraction of 0.5 Gy had encouraging results in oxygen-dependent patients with COVID-19 pneumonia.
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http://dx.doi.org/10.1016/j.ijrobp.2020.07.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373065PMC
December 2020

National Communicable Disease Surveillance System: A review on Information and Organizational Structures in Developed Countries.

Acta Inform Med 2017 Dec;25(4):271-276

Department of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Behesti University of Medical Sciences, Tehran, Iran.

Introduction: To obtain necessary information for managing communicable diseases, different countries have developed national communicable diseases surveillance systems (NCDSS). Exploiting the lesson learned from the leading countries in development of surveillance systems provides the foundation for developing these systems in other countries. In this study, the information and organizational structure of NCDSS in developed countries were reviewed.

Methods: The study reviewed publications found on the organizational structure, content and data flow of NCDSS in the United States of America (USA), Australia and Germany that were published in English between 2000 and 2016. The publications were identified by searching the CINAHL, Science Direct, ProQuest, PubMed, Google Scholar databases and the related databases in selected countries.

Results: Thirty-four studies were investigated. All of the reviewed countries have implemented the NCDSS. In majority of countries the department of health (DoH) is responsible for managing this system. The reviewed countries have created a minimum data set for reporting communicable diseases data and information.

Conclusion: For developing NCDSS, establishing coordinator centers, setting the effective policies and procedures, providing appropriate communication infrastructures for data exchange and defining a communicable diseases minimum data set are essential.
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http://dx.doi.org/10.5455/aim.2017.25.271-276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723198PMC
December 2017

Study of patient complaints reported over 30 months at a large heart centre in Tehran.

Qual Saf Health Care 2010 Oct 14;19(5):e28. Epub 2010 Jun 14.

Health and Management Department, Faculty of Health, Mashhad University of Medical Sciences, Mashhad 9185763788, Iran.

Objectives: To determine the rate and nature of complaints and the outcomes of the complaint management at a large heart centre in Tehran.

Design: A retrospective review of all verbal and written complaints recorded over 30 months.

Setting: A large heart centre in Tehran, Iran. Population All 312,105 admissions (47,041 inpatients, 138,842 outpatients and 126,222 ambulatory services) between July 2005 and January 2007 at Tehran Heart Centre, during which the hospital received 1642 verbal and written complaints.

Main Outcome Measures: Proportion of admissions with verbal and written complaints, type of complaints and outcomes of the complaint management.

Results: A total of 1642 (5.2 per 1000) complaints were received, of which 1457 (4.64 per 1000) were verbal, and 185 (0.56 per 1000) were in written format. 34.7% of the complaints were related to admission procedures, followed by 34.1% communication, 13.8% waiting time, 6.8% delay and 4.1% ignoring the standards of clinical care. Over 90% of complaints were resolved by explanation or verbal apology, 2.1% of them led to a change in the process or procedure, and 4.8% were deemed disapproved claims.

Conclusions: The majority of patient complaints in Tehran Heart Centre are related to admission procedures or communication; most of them are verbal and resolved in the early stage as an explanation or apology. The hospital complaint management system has the potential to resolve the majority of such complaints in an early stage.
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http://dx.doi.org/10.1136/qshc.2009.033654DOI Listing
October 2010