Publications by authors named "Mohammad Aberomand"

4 Publications

  • Page 1 of 1

Evaluating the activity of salivary enzymes as stress biomarkers under psychological stress and their relationship with rumination and personality traits.

Biomarkers 2021 Jul 6;26(5):477-482. Epub 2021 May 6.

Student Research Committee, Department of Clinical Biochemistry, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Background: Salivary enzymes are used as non-invasive biomarkers to assess the activity of the sympathetic-adrenal-medullary system. The aim of this study was to evaluated levels of acid phosphatase, beta-glucuronidase and cathepsin salivary enzymes under psychological tension and their connection with rumination and personality traits.

Methods: A total of 60 medical students, who wanted to participate in the final exam, two months before the exam, the inventory emotional control questionnaire and the neo-short form were completed. Saliva samples were taken in both the basal conditions and under exam stress.

Results: A significant difference was found between the mean of level salivary enzymes in rest and under exam stress. Also, we found a positive and significant correlation between the activity of salivary enzymes and personality traits such as neuroticism, extraversion, agreeableness and rumination ( < .01,  < .05) level. Neuroticism, agreeableness and rumination predicted 45% of the variance of salivary acid phosphatase, neuroticism and rumination predicted 49% of the variance of salivary beta-glucuronidase and neuroticism, extraversion and rumination predicted 38% of the variance of salivary cathepsin under stress exam.

Conclusion: The results of this study show, levels of salivary enzymes may increase in individuals with traits of neuroticism, extraversion, agreeableness and rumination through response to psychological stressors.
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http://dx.doi.org/10.1080/1354750X.2021.1919762DOI Listing
July 2021

Effects of the Hydroalcoholic Extract of on Arginase I Activity and Expression in the Retina of Streptozotocin-Induced Diabetic Rats.

Int J Endocrinol Metab 2017 Apr 13;15(2):e42161. Epub 2017 Feb 13.

Hyperlipidemia Research Center, Department of Clinical Biochemistry, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.

Background: Emerging evidence suggests that an increased arginase activity is involved in vascular dysfunction in experimental animals. Roscoe, commonly known as ginger, has been widely used in the traditional medicine for treatment of diabetes.

Objectives: This study aimed at investigating the effects of the hydroalcoholic extract of on arginase I activity and expression in the retina of streptozotocin (STZ)-induced diabetic rats.

Methods: In this experimental study, 16 male Wistar rats weighing 200 - 250 g were assessed. Diabetes was induced via a single intraperitoneal injection of STZ (60 mg/kg body weight). The rats were randomly allocated into four experimental groups. Untreated healthy and diabetic controls received 1.5 mL/kg distilled water. Treated diabetic rats received 200, and 400 mg/kg of the extract dissolved in distilled water (1.5 mL/kg). Body weight, blood glucose and insulin concentration were measured by standard methods. The arginase I activity and expression were determined by spectrophotometric and western blot analysis, respectively.

Results: Our results showed that blood glucose concentration was significantly decreased in diabetic rats treated with the extract compared to untreated diabetic controls (P < 0.01). Treatment with 400 mg/kg of the extract reduced arginase I activity and expression (P < 0.05). A significant elevation in body weight was observed in diabetic rats treated with the extract. Serum insulin was significantly increased in diabetic rats treated with 400 mg/kg of the extract compared to diabetic controls (P < 0.05).

Conclusions: Our results suggest that the hydroalcoholic extract may potentially be a promising therapeutic option for treating diabetes-induced vascular disorders, possibly through reducing arginase I activity and expression in the retina.
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http://dx.doi.org/10.5812/ijem.42161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555732PMC
April 2017

Salivary Testosterone Levels Under Psychological Stress and Its Relationship with Rumination and Five Personality Traits in Medical Students.

Psychiatry Investig 2016 Nov 24;13(6):637-643. Epub 2016 Nov 24.

Department of Psychology, Faculty of Psychology, Behbahan Branch, Islamic Azad University, Behbahan, Iran.

Objective: The purpose of this study was to evaluate the salivary testosterone levels under psychological stress and its relationship with rumination and five personality traits in medical students.

Methods: A total of 58 medical students, who wanted to participate in the final exam, were selected by simple random sampling. Two months before the exam, in the basal conditions, the NEO Inventory short form, and the Emotional Control Questionnaire (ECQ) were completed. Saliva samples were taken from students in both the basal conditions and under exam stress. Salivary testosterone was measured by ELISA. Data was analyzed using multivariate analysis of variance with repeated measures, paired samples t-test, Pearson correlation and stepwise regression analysis.

Results: Salivary testosterone level of men showed a significant increase under exam stress (p<0.05). However, a non-significant although substantial reduction observed in women. A significant correlation was found between extroversion (r=-0.33) and openness to experience (r=0.30) with salivary testosterone (p<0.05). Extraversion, aggression control and emotional inhibition predicted 28% of variance of salivary testosterone under stress.

Conclusion: Salivary testosterone reactivity to stress can be determined by sexual differences, personality traits, and emotional control variables which may decrease or increase stress effects on biological responses, especially the salivary testosterone.
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http://dx.doi.org/10.4306/pi.2016.13.6.637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5128352PMC
November 2016

Investigation of respirable particulate matter pollutants on air-breathing zone workers in the Beam Rolling Mills Factory (Iran National Steel Industrial Group), Ahvaz, Iran.

Indian J Occup Environ Med 2008 Aug;12(2):71-5

Department of Occupational Hygiene, Imam Hospital, Ahvaz Jundishapour University of Medical Sciences, Ahvaz, Iran.

Workers of iron and steel factories are exposed to a wide range of pollutants depending on the particular process, the materials involved, the effectiveness of monitoring and the control measures. Adverse effects are determined by the physical state and propensities of the pollutant involved, the intensity and duration of the exposure, the extent of pollutant accumulation in the body and the sensitivity of the individual to its effects. The main aim of this study is to assess the levels of the indoor respirable particulate matter (RPM) and to compare the health condition of exposed workers, with nonexposed employees group. Line 630 has only one furnace of 40 tons and line 650 has two furnaces of 20 and 40 tons capacity due to which the mean of the RPM concentrations in the breathing zone was significantly different (P < 0.05) in line 650 but not in line 630 as compared with National Institute for Occupational Safety and Hygiene's (3 mg/m(3)). The average of the RPM concentrations in production line 650 is higher than that of production line 630, with the 95% confidence interval in saw cabin station number 1 of production line 650.
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http://dx.doi.org/10.4103/0019-5278.43264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796760PMC
August 2008
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