Publications by authors named "Mohamed Lamkanfi"

100Publications

Familial Mediterranean Fever and COVID-19: Friends or Foes?

Front Immunol 2020 18;11:574593. Epub 2020 Sep 18.

Division of Internal Medicine, Clinica Medica "A Murri", Department of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, Bari, Italy.

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http://dx.doi.org/10.3389/fimmu.2020.574593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530822PMC
October 2020

Therapeutic modulation of inflammasome pathways.

Immunol Rev 2020 Sep 7;297(1):123-138. Epub 2020 Aug 7.

Laboratory of Medical Innate Immunity, Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1111/imr.12908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497261PMC
September 2020

An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages.

Cell Rep 2020 Jul;32(4):107959

Department of Internal Medicine and Pediatrics, Ghent University, 9052 Ghent, Belgium; VIB Center for Inflammation Research, 9052 Ghent, Belgium; Janssen Immunosciences, World Without Disease Accelerator, Pharmaceutical Companies of Johnson & Johnson, Beerse 2340, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408007PMC
July 2020

Snapshot of a Deadly Embrace: The Caspase-1-GSDMD Interface.

Immunity 2020 Jul;53(1):6-8

Laboratory of Medical Innate Immunity, Department of Internal Medicine and Pediatrics, Ghent University, B-9000 Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.06.019DOI Listing
July 2020

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis.

Nature 2019 11 20;575(7784):683-687. Epub 2019 Nov 20.

Institute for Medical Microbiology, Immunology and Hygiene (IMMIH), CECAD Research Center, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.1038/s41586-019-1770-6DOI Listing
November 2019

El Tor Biotype Activates the Caspase-11-Independent Canonical Nlrp3 and Pyrin Inflammasomes.

Front Immunol 2019 29;10:2463. Epub 2019 Oct 29.

Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.3389/fimmu.2019.02463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828848PMC
November 2020

Recent Insights on Inflammasomes, Gasdermin Pores, and Pyroptosis.

Cold Spring Harb Perspect Biol 2020 05 1;12(5). Epub 2020 May 1.

Department of Internal Medicine and Pediatrics, Ghent University, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1101/cshperspect.a036392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197430PMC
May 2020

Structure of S-layer protein Sap reveals a mechanism for therapeutic intervention in anthrax.

Nat Microbiol 2019 11 15;4(11):1805-1814. Epub 2019 Jul 15.

Structural and Molecular Microbiology, Structural Biology Research Center, VIB, Brussels, Belgium.

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http://www.nature.com/articles/s41564-019-0499-1
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http://dx.doi.org/10.1038/s41564-019-0499-1DOI Listing
November 2019

Caspases in Cell Death, Inflammation, and Disease.

Immunity 2019 06;50(6):1352-1364

Janssen Immunosciences, World Without Disease Accelerator, Pharmaceutical Companies of Johnson & Johnson, Beerse, 2340, Belgium; Department of Internal Medicine and Pediatrics, Ghent University, Ghent, 9000, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.05.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611727PMC
June 2019

The emerging roles of inflammasome-dependent cytokines in cancer development.

EMBO Rep 2019 06 17;20(6). Epub 2019 May 17.

Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium

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http://dx.doi.org/10.15252/embr.201847575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549028PMC
June 2019

Defining the Impact of Host Genotypes on Microbiota Composition Requires Meticulous Control of Experimental Variables.

Immunity 2018 04;48(4):605-607

Department of Physiology and Pharmacology and Gastrointestinal Research Group, Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, AB, T2N 4N1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.04.001DOI Listing
April 2018

A new lead to NLRP3 inhibition.

J Exp Med 2017 11 23;214(11):3147-3149. Epub 2017 Oct 23.

VIB-UGent Center for Inflammation Research, VIB; and Department of Internal Medicine, Ghent University, Ghent, Belgium; Department of Physiological Chemistry, Genentech, South San Francisco, CA

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http://www.jem.org/lookup/doi/10.1084/jem.20171848
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http://dx.doi.org/10.1084/jem.20171848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678032PMC
November 2017

Inflammasome-Dependent Cytokines at the Crossroads of Health and Autoinflammatory Disease.

Cold Spring Harb Perspect Biol 2019 01 2;11(1). Epub 2019 Jan 2.

Center for Inflammation Research, VIB, Zwijnaarde B-9052, Belgium.

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http://dx.doi.org/10.1101/cshperspect.a028563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314066PMC
January 2019

Gold nanodome SERS platform for label-free detection of protease activity.

Faraday Discuss 2017 12;205:345-361

Photonics Research Group, INTEC, Ghent University - imec, Belgium.

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http://dx.doi.org/10.1039/c7fd00124jDOI Listing
December 2017

In Retrospect: The inflammasome turns 15.

Nature 2017 08;548(7669):534-535

Department of Physiological Chemistry, Genentech, South San Francisco, California 94080, USA.

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http://www.nature.com/doifinder/10.1038/548534a
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http://dx.doi.org/10.1038/548534aDOI Listing
August 2017

Nlrp6- and ASC-Dependent Inflammasomes Do Not Shape the Commensal Gut Microbiota Composition.

Immunity 2017 08 8;47(2):339-348.e4. Epub 2017 Aug 8.

Department of Internal Medicine, Ghent University, Ghent, Belgium; VIB-UGent Center for Inflammation Research, VIB, Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.07.011DOI Listing
August 2017

Immunology: Gut sensor halts viral attack.

Nature 2017 06 21;546(7660):606-608. Epub 2017 Jun 21.

Center for Inflammation Research, VIB, Ghent B-9052, Belgium, and in the Department of Internal Medicine, Ghent University.

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http://dx.doi.org/10.1038/nature23090DOI Listing
June 2017

NLRP2 controls age-associated maternal fertility.

J Exp Med 2016 12 23;213(13):2851-2860. Epub 2016 Nov 23.

Inflammation Research Center, VIB, B-9052 Zwijnaarde, Belgium

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http://dx.doi.org/10.1084/jem.20160900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154945PMC
December 2016

General Strategies in Inflammasome Biology.

Curr Top Microbiol Immunol 2016 ;397:1-22

NOD-like Receptor and Inflammasome Laboratory, Inflammation Research Center, VIB, 9052, Zwijnaarde, Belgium.

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http://link.springer.com/10.1007/978-3-319-41171-2_1
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http://dx.doi.org/10.1007/978-3-319-41171-2_1DOI Listing
June 2017

Pyroptosis.

Curr Biol 2016 07;26(13):R568-R572

NOD-like receptor and Inflammasome Laboratory, Inflammation Research Center, VIB, Technologiepark 927, Zwijnaarde, B-9052, Belgium; Department of Internal Medicine, Ghent University, Ghent, B-9000, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2016.02.019DOI Listing
July 2016

Inflammasomes as polyvalent cell death platforms.

Cell Mol Life Sci 2016 06 5;73(11-12):2335-47. Epub 2016 Apr 5.

NOD-like Receptor and Inflammasome Laboratory, Inflammation Research Center, VIB, Technologiepark 927, B-9052, Zwijnaarde, Belgium.

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http://dx.doi.org/10.1007/s00018-016-2204-3DOI Listing
June 2016

The NEK-sus of the NLRP3 inflammasome.

Nat Immunol 2016 Mar;17(3):223-4

Inflammation Research Center, VIB, Ghent, Belgium, and the Department of Internal Medicine, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1038/ni.3391DOI Listing
March 2016

Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes.

J Neuroinflammation 2015 Aug 8;12:143. Epub 2015 Aug 8.

Unit Immunoregulation and Mucosal Immunology, GROUP-ID Consortium, VIB Inflammation Research Centre, Technologiepark 927, B-9052, Gent, Belgium.

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http://dx.doi.org/10.1186/s12974-015-0367-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528710PMC
August 2015

Protective and detrimental roles of inflammasomes in disease.

Semin Immunopathol 2015 Jul 21;37(4):313-22. Epub 2015 Apr 21.

Department of Medical Protein Research, VIB, Albert Baertsoenkaai 3, B-9000, Ghent, Belgium.

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http://dx.doi.org/10.1007/s00281-015-0485-5DOI Listing
July 2015

CARD- and pyrin-only proteins regulating inflammasome activation and immunity.

Immunol Rev 2015 May;265(1):217-30

Department of Medical Protein Research, VIB, Ghent, Belgium; Department of Biochemistry, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1111/imr.12282DOI Listing
May 2015

Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection.

Cell Host Microbe 2015 Mar 19;17(3):357-368. Epub 2015 Feb 19.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359672PMC
March 2015

Cutting edge: SHARPIN is required for optimal NLRP3 inflammasome activation.

J Immunol 2015 Mar 30;194(5):2064-7. Epub 2015 Jan 30.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105;

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http://dx.doi.org/10.4049/jimmunol.1402951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340749PMC
March 2015

Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5.

Proc Natl Acad Sci U S A 2015 Feb 20;112(5):1541-6. Epub 2015 Jan 20.

Department of Medical Protein Research, VIB, Ghent B-9000, Belgium; Department of Biochemistry, Ghent University, Ghent B-9000, Belgium;

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http://dx.doi.org/10.1073/pnas.1417945112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321312PMC
February 2015

Sensing the enemy within: how macrophages detect intracellular Gram-negative bacteria.

Trends Biochem Sci 2014 Dec 4;39(12):574-6. Epub 2014 Nov 4.

Department of Medical Protein Research, VIB, Ghent, B-9000, Belgium; Department of Biochemistry, Ghent University, Ghent, B-9000, Belgium. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09680004140018
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http://dx.doi.org/10.1016/j.tibs.2014.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247376PMC
December 2014

Reactive oxygen species regulate caspase-11 expression and activation of the non-canonical NLRP3 inflammasome during enteric pathogen infection.

PLoS Pathog 2014 Sep 25;10(9):e1004410. Epub 2014 Sep 25.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178001PMC
September 2014

NOD-like receptors interfacing the immune and reproductive systems.

FEBS J 2014 Oct 30;281(20):4568-82. Epub 2014 Sep 30.

Department of Medical Protein Research, VIB, Ghent, Belgium; Department of Biochemistry, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1111/febs.13014DOI Listing
October 2014

Mechanisms and functions of inflammasomes.

Cell 2014 May;157(5):1013-22

Department of Physiological Chemistry, Genentech, South San Francisco, CA 94080, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674140047
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http://dx.doi.org/10.1016/j.cell.2014.04.007DOI Listing
May 2014

Inflammasomes in respiratory disease: from bench to bedside.

Chest 2014 May;145(5):1121-1133

Laboratory for Translational Research of Obstructive Pulmonary Disease, Ghent University Hospital, Ghent, Belgium; Departments of Epidemiology and Respiratory Medicine, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1378/chest.13-1885DOI Listing
May 2014

Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation.

Nat Commun 2014 ;5:3209

1] Department of Medical Protein Research, VIB, Ghent B-9000, Belgium [2] Department of Biochemistry, Ghent University, Ghent B-9000, Belgium [3].

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http://www.nature.com/articles/ncomms4209
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http://dx.doi.org/10.1038/ncomms4209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926011PMC
October 2015

Critical role for inflammasome-independent IL-1β production in osteomyelitis.

Proc Natl Acad Sci U S A 2014 Jan 6;111(3):1066-71. Epub 2014 Jan 6.

Department of Immunology, Small Animal Imaging Core, and Animal Resources Center and the Veterinary Pathology Core, St. Jude Children's Research Hospital, Memphis, TN 38105.

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http://dx.doi.org/10.1073/pnas.1318688111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903206PMC
January 2014

Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection.

Proc Natl Acad Sci U S A 2014 Jan 17;111(1):385-90. Epub 2013 Dec 17.

Department of Immunology and Animal Resources Center and the Veterinary Pathology Core, St. Jude Children's Research Hospital, Memphis, TN 38105.

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http://dx.doi.org/10.1073/pnas.1317643111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890849PMC
January 2014

The small GTPase Arf6 is essential for the Tram/Trif pathway in TLR4 signaling.

J Biol Chem 2014 Jan 2;289(3):1364-76. Epub 2013 Dec 2.

From the Department of Medical Protein Research, Cytokine Receptor Lab, VIB, Ghent B-9000, Belgium.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M113.499194
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http://dx.doi.org/10.1074/jbc.M113.499194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894321PMC
January 2014

K⁺ drops tilt the NLRP3 inflammasome.

Immunity 2013 Jun;38(6):1085-8

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10747613130024
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http://dx.doi.org/10.1016/j.immuni.2013.06.001DOI Listing
June 2013

RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3.

Nature 2013 Jun 26;498(7453):224-7. Epub 2013 May 26.

Department of Immunology, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1038/nature12174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683390PMC
June 2013

Inflammasomes and their roles in health and disease.

Annu Rev Cell Dev Biol 2012 10;28:137-61. Epub 2012 Sep 10.

Department of Biochemistry, Ghent University, Ghent 9000, Belgium.

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http://www.annualreviews.org/doi/10.1146/annurev-cellbio-101
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http://dx.doi.org/10.1146/annurev-cellbio-101011-155745DOI Listing
March 2013

Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines.

Nat Immunol 2012 Jul;13(7):701-2

Department of Immunology St. Jude Children’s Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1038/ni.2389DOI Listing
July 2012

Phosphorylation of NLRC4 is critical for inflammasome activation.

Nature 2012 Oct 12;490(7421):539-42. Epub 2012 Aug 12.

Department of Physiological Chemistry, Genentech Inc., 1 DNA Way, South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1038/nature11429DOI Listing
October 2012

The inflammasome: a remote control for metabolic syndrome.

Cell Res 2012 Jul 10;22(7):1095-8. Epub 2012 Apr 10.

Department of Biochemistry, Ghent University, Ghent, Belgium.

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http://www.nature.com/articles/cr201255
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http://dx.doi.org/10.1038/cr.2012.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391019PMC
July 2012

Role of inflammasomes in host defense against Citrobacter rodentium infection.

J Biol Chem 2012 May 29;287(20):16955-64. Epub 2012 Mar 29.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1074/jbc.M112.358705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351318PMC
May 2012

Regulation of immune pathways by the NOD-like receptor NLRC5.

Immunobiology 2012 Jan 8;217(1):13-6. Epub 2011 Sep 8.

Department of Biochemistry, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.imbio.2011.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3225722PMC
January 2012

Non-canonical inflammasome activation targets caspase-11.

Nature 2011 Oct 16;479(7371):117-21. Epub 2011 Oct 16.

Department of Physiological Chemistry, Genentech Inc., South San Francisco, California 94080, USA.

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http://dx.doi.org/10.1038/nature10558DOI Listing
October 2011

NOD-like receptors and the innate immune system: coping with danger, damage and death.

Cytokine Growth Factor Rev 2011 Oct-Dec;22(5-6):257-76. Epub 2011 Oct 12.

Department for Molecular Biomedical Research, Unit for Molecular Signaling and Cell Death, Technologiepark 927, B-9052 Ghent, Belgium.

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http://dx.doi.org/10.1016/j.cytogfr.2011.09.003DOI Listing
April 2012

Deregulated inflammasome signaling in disease.

Immunol Rev 2011 Sep;243(1):163-73

Department of Biochemistry, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1111/j.1600-065X.2011.01042.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170132PMC
September 2011

Modulation of inflammasome pathways by bacterial and viral pathogens.

J Immunol 2011 Jul;187(2):597-602

Department of Biochemistry, Ghent University, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.4049/jimmunol.1100229DOI Listing
July 2011

HMGB1 release by inflammasomes.

Virulence 2011 Mar-Apr;2(2):162-5. Epub 2011 Mar 1.

Department of Biochemistry, Ghent University, Ghent, Belgium.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265758PMC
http://dx.doi.org/10.4161/viru.2.2.15480DOI Listing
August 2011

The Nlrp3 inflammasome: contributions to intestinal homeostasis.

Trends Immunol 2011 Apr;32(4):171-9

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.it.2011.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070791PMC
April 2011

Emerging inflammasome effector mechanisms.

Authors:
Mohamed Lamkanfi

Nat Rev Immunol 2011 03;11(3):213-20

Department of Biochemistry, Ghent University, Ghent, Belgium.

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http://www.nature.com/articles/nri2936
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http://dx.doi.org/10.1038/nri2936DOI Listing
March 2011

Inflammasomes and Intestinal Tumorigenesis.

Drug Discov Today Dis Mech 2011 ;8(3-4):e71-e78

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S17406765110001
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http://dx.doi.org/10.1016/j.ddmec.2011.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3388509PMC
January 2011

Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia.

J Immunol 2010 Oct 27;185(7):4385-92. Epub 2010 Aug 27.

Department of Physiological Chemistry, Genentech, South San Francisco, CA 94080, USA.

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http://dx.doi.org/10.4049/jimmunol.1000803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3428148PMC
October 2010

Cutting edge: proteolytic inactivation of poly(ADP-ribose) polymerase 1 by the Nlrp3 and Nlrc4 inflammasomes.

J Immunol 2010 Sep 16;185(6):3127-30. Epub 2010 Aug 16.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105-2794, USA.

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http://dx.doi.org/10.4049/jimmunol.1001512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104018PMC
September 2010

Manipulation of host cell death pathways during microbial infections.

Cell Host Microbe 2010 Jul;8(1):44-54

Department of Biochemistry, Ghent University, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1016/j.chom.2010.06.007DOI Listing
July 2010

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella.

J Exp Med 2010 Aug 5;207(8):1745-55. Epub 2010 Jul 5.

Department of Microbiology and Immunology, Stanford School of Medicine, Stanford University, Stanford, CA, USA.

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http://dx.doi.org/10.1084/jem.20100257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916133PMC
August 2010

The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis.

Immunity 2010 Mar 18;32(3):379-91. Epub 2010 Mar 18.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.immuni.2010.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982187PMC
March 2010

NOD-like receptor (NLR) signaling beyond the inflammasome.

Eur J Immunol 2010 Mar;40(3):624-7

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105-2794, USA.

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http://dx.doi.org/10.1002/eji.200940211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001129PMC
March 2010