Dr. Mohamed Abdo Rizk, PhD - Mansoura University - Assistant Professor

Dr. Mohamed Abdo Rizk

PhD

Mansoura University

Assistant Professor

Obihiro-Japan, Hokkaido | Japan

Main Specialties: Infectious Disease, Internal Medicine

Additional Specialties: Internal medicine and Infectious diseases

ORCID logohttps://orcid.org/0000-0002-5250-6172


Top Author

Dr. Mohamed Abdo Rizk, PhD - Mansoura University - Assistant Professor

Dr. Mohamed Abdo Rizk

PhD

Introduction

Dr. Mohamed Abdo Rizk holds a DVM degree from Faculty of Veterinary Medicine, Mansoura University. He obtained his Master degree in 2011 in veterinary internal medicine from School of Veterinary Medicine, Mansoura University and obtained his joint PhD (Egypt/Japan) at 2016 in internal medicine from Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan. Dr. Mohamed Abdo Rizk has more than 8 years of experience in veterinary internal medicine and infectious diseases. Beside his research experience in that area, he has 9 years of teaching experience primarily related to teaching veterinary internal medicine and infectious diseases to DVM students. He has many publications in national and international scientific journals. He received the prize of the best PhD thesis in Mansoura University at 2016. He trained in horse clinic and small clinic in University of Veterinary Medicine Hannover, Hannover, Germany. He worked as foreign visiting researcher at National Research Center of Protozoan Diseases (NRCPD), Obihiro University of Agriculture and Veterinary Medicine, Hokkaido, Japan. Currently he is assistant professor of internal medicine and infectious diseases at Faculty of Veterinary Medicine, Mansoura University.

Primary Affiliation: Mansoura University - Obihiro-Japan, Hokkaido , Japan

Specialties:

Additional Specialties:

Research Interests:


View Dr. Mohamed Abdo Rizk’s Resume / CV

Education

Jun 2016 - Dec 2016
Obihiro Chikusan Daigaku
Dr./Foreign Visiting Researcher
National Research Center for Protozoan Diseases
Mar 2016
Mansoura University Faculty of Veterinary Medicine
Dr./Assistant Professor
Internal Medicine and Infectious Diseases

Experience

Nov 2016
Best PhD thesis in Mansoura University, Egypt

Publications

41Publications

377Reads

147Profile Views

7PubMed Central Citations

Closing the empty anti-Babesia gibsoni drug pipeline in vitro using fluorescence-based high throughput screening assay.

Parasitol Int 2020 Apr 10;75:102054. Epub 2020 Jan 10.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro, Hokkaido 080-8555, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.parint.2020.102054DOI Listing
April 2020
2.111 Impact Factor

Drug screening of food and drug administration-approved compounds against Babesia bovis in vitro.

Exp Parasitol 2020 Mar 8;210:107831. Epub 2020 Jan 8.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, 080-8555, Hokkaido, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.exppara.2020.107831DOI Listing
March 2020
1.859 Impact Factor

Transient Transfection of the Zoonotic Parasite .

Pathogens 2020 Feb 10;9(2). Epub 2020 Feb 10.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.

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http://dx.doi.org/10.3390/pathogens9020108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169379PMC
February 2020

Myrrh Oil Inhibitory Growth on Bovine and Equine Piroplasm Parasites and of Mice.

Pathogens 2020 Feb 29;9(3). Epub 2020 Feb 29.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro, Hokkaido 080-8555, Japan.

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http://dx.doi.org/10.3390/pathogens9030173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7157210PMC
February 2020

Cocktail Babesia bovis antigens for global detection of Babesia bovis infection in cattle.

Exp Parasitol 2019 Nov 12;206:107758. Epub 2019 Sep 12.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro, Hokkaido, 080-8555, Japan.

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http://dx.doi.org/10.1016/j.exppara.2019.107758DOI Listing
November 2019
5 Reads
1.859 Impact Factor

Discovering the in vitro potent inhibitors against Babesia and Theileria parasites by repurposing the Malaria Box: A review.

Vet Parasitol 2019 Oct 19;274:108895. Epub 2019 Jul 19.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido 080-8555, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03044017193016
Publisher Site
http://dx.doi.org/10.1016/j.vetpar.2019.07.003DOI Listing
October 2019
1 Read
2.460 Impact Factor

Screening the Medicines for Malaria Venture Pathogen Box against piroplasm parasites.

Int J Parasitol Drugs Drug Resist 2019 08 19;10:84-90. Epub 2019 Jun 19.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture Veterinary Medicine, Nishi 2 Sen-13, Inada-cho, Obihiro, Hokkaido, 080-8555, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ijpddr.2019.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603297PMC
August 2019
4 Reads
2.514 Impact Factor

The first molecular detection of Clostridium perfringens from pneumonic cases associated with foot and mouth disease in cattle and buffalo in Egypt.

Trop Anim Health Prod 2019 May 28;51(4):847-852. Epub 2018 Nov 28.

Department of Internal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Mansoura University, Mansoura, 35516, Egypt.

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http://link.springer.com/10.1007/s11250-018-1763-8
Publisher Site
http://dx.doi.org/10.1007/s11250-018-1763-8DOI Listing
May 2019
37 Reads
0.820 Impact Factor

Antimicrobial resistance profiles and virulence genotyping of Salmonella enterica serovars recovered from broiler chickens and chicken carcasses in Egypt.

BMC Vet Res 2019 Apr 27;15(1):124. Epub 2019 Apr 27.

Department of Internal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Mansoura University, Mansoura, 35516, Egypt.

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http://dx.doi.org/10.1186/s12917-019-1867-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486964PMC
April 2019
7 Reads
1.777 Impact Factor

Evaluation of the in vitro and in vivo inhibitory effect of thymoquinone on piroplasm parasites.

Parasit Vectors 2019 Jan 16;12(1):37. Epub 2019 Jan 16.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro, Hokkaido, Japan.

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http://dx.doi.org/10.1186/s13071-019-3296-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335684PMC
January 2019
17 Reads
3.430 Impact Factor

Inhibitory effects of fluoroquinolone antibiotics on and , blood parasites of veterinary and zoonotic importance.

Infect Drug Resist 2018 28;11:1605-1615. Epub 2018 Sep 28.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro, Hokkaido, Japan,

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https://www.dovepress.com/inhibitory-effects-of-fluoroquinol
Publisher Site
http://dx.doi.org/10.2147/IDR.S159519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166754PMC
September 2018
9 Reads

The effects of nitidine chloride and camptothecin on the growth of Babesia and Theileria parasites.

Ticks Tick Borne Dis 2018 07 27;9(5):1192-1201. Epub 2018 Apr 27.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture Veterinary Medicine, Nishi 2 Sen-11, Inada-cho, Obihiro, Hokkaido 080-8555, Japan. Electronic address:

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https://www.researchgate.net/publication/262979477_Evaluatio
Web Search
https://linkinghub.elsevier.com/retrieve/pii/S1877959X173058
Publisher Site
http://dx.doi.org/10.1016/j.ttbdis.2018.04.019DOI Listing
July 2018
29 Reads
2.720 Impact Factor

17-DMAG inhibits the multiplication of several Babesia species and Theileria equi on in vitro cultures, and Babesia microti in mice.

Int J Parasitol Drugs Drug Resist 2018 04 1;8(1):104-111. Epub 2018 Mar 1.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2-13 Inada-cho, Obihiro 080-8555, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ijpddr.2018.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114103PMC
April 2018
17 Reads
2.514 Impact Factor

Molecular identification and antigenic characterization of Babesia divergens Erythrocyte Binding Protein (BdEBP) as a potential vaccine candidate.

Parasitol Int 2017 Dec 22;66(6):721-726. Epub 2017 Jul 22.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro, Hokkaido, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.parint.2017.07.004DOI Listing
December 2017
31 Reads
2.111 Impact Factor

Comparative therapeutic effect of steroidal and non-steroidal anti-inflammatory drugs on pro-inflammatory cytokine production in water buffalo calves (Bubalus bubalis) naturally infected with bronchopneumonia: a randomized clinical trial.

Trop Anim Health Prod 2017 Dec 22;49(8):1723-1731. Epub 2017 Aug 22.

Department of Animal Medicine, Faculty of Veterinary Medicine, Sohag University, Sohag, 82524, Egypt.

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http://link.springer.com/10.1007/s11250-017-1383-8
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http://dx.doi.org/10.1007/s11250-017-1383-8DOI Listing
December 2017
88 Reads
0.820 Impact Factor

Evaluation of Ascorbic Acid in Combination of Ivermectin in Augmentation the Recovery from Juvenile Generalized Demodicosis in Dogs: A Randomized Clinical Trial

Rizk, M.A., Abdalla, A.A., El-Sayed, S.A.E.S., 2017. Evaluation of Ascorbic Acid in Combination of I

PSM Veterinary Research

The clinical form of canine juvenile generalized demodicosis is usually related genetically with immune deficiency. In this regard, in the current study we have evaluated the impact of immunostimulant agent as ascorbic acid (AA) on the rapid recovery of dogs naturally affected by generalized demodicosis. To achieve this purpose, twenty- eight German Shepherd male dogs were used in this study and divided randomly into two groups, then received daily oral dose of ivermectin (IVR) 1% (0.5 mg kg-1) alone and IVR 1% in combination with AA (500 mg per animal, twice daily) for two months, respectively. Total mite numbers, egg counts, eosinophil counts and skin lesion score were used for assessment the treatment efficacy after 30, 60, 90, and 120 days subsequent to the initial treatment. Seventeen dogs (IVR (n = 8), and IVR + AA (n = 9)) completed the full length of experiment (4- months) as 11 dogs were withdrawn due to various causes. Out of 17 dogs completing the 4 months trial, two dogs treated with IVR + AA combination therapy achieved the parasitological cure. The results revealed rapid and marked reduction in the total mite numbers and eosinophil counts treated with combination therapy in comparison with those administrated ivermectin alone. These findings exhibited the potential anti-Demodex effect of ivermectin when administrated in combination with immunostimulant agent and highlight the impact of an inexpensive, available and immunomodulatory agent as ascorbic acid in treatment of canine juvenile generalized demodicosis.

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November 2017
22 Reads

Performance and consistency of a fluorescence-based high-throughput screening assay for use in Babesia drug screening in mice.

Sci Rep 2017 10 16;7(1):12774. Epub 2017 Oct 16.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro, Hokkaido, 080-8555, Japan.

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http://dx.doi.org/10.1038/s41598-017-13052-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643553PMC
October 2017
38 Reads
1 Citation
5.080 Impact Factor

Evaluation of the inhibitory effect of N-acetyl-L-cysteine on Babesia and Theileria parasites.

Exp Parasitol 2017 Aug 24;179:43-48. Epub 2017 Jun 24.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-Cho, Obihiro, Hokkaido, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.exppara.2017.06.003DOI Listing
August 2017
23 Reads
1 Citation
1.860 Impact Factor

An epidemiological survey of bovine Babesia and Theileria parasites in cattle, buffaloes, and sheep in Egypt.

Parasitol Int 2015 Feb 14;64(1):79-85. Epub 2014 Oct 14.

National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido 080-8555, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.parint.2014.10.002DOI Listing
February 2015
45 Reads
5 Citations
2.111 Impact Factor

REFERENCES CONTENT ALERTS Evaluation of a Fluorescence-Based Method for Antibabesial Drug Screening

Antimicrobial Agents and Chemotherapy

In vitro evaluation of chemotherapeutic agents against Babesia and Theileria parasites has become routine, and the effectiveness of these chemicals is usually determined by comparing the parasitemia dynamics of untreated and treated parasites. Although microscopy is widely used to calculate parasitemia, several disadvantages are associated with this technique. The present study evaluated a fluorescence-based method using SYBR green I stain (SG I) to screen antibabesial agents in in vitro cultures of Babe- sia bovis. The linearity between relative fluorescence units (RFU) and parasitemia was found to be well correlated with a 0.9944 goodness-of-fit (r2) value. Subsequently, 50% inhibitory concentration (IC50) values were calculated for 3 antiprotozoan agents, diminazene aceturate, nimbolide, and gedunin, by this method. For diminazene aceturate and nimbolide, the IC50s determined by the fluorescence-based method (408 nM and 8.13

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June 2014
28 Reads

A comparative study on selected acute-phase proteins (APPs) and immunoglobulins in buffalo and bovine calves with respiratory disease

DOI 10.1007/s00580-014-1933-7

Comp Clin Pathol

Cytokines play an important role in innate immune response to diseases in bovine calves. The objective of the present study was to assess the comparative changes of se- lected acute-phase proteins (APPs) and immunoglobulins in buffalo and bovine calves with respiratory disease. For this purpose, a total of 65 calves (28 buffalo and 37 bovine) were studied. Of all, 45 calves (21 buffalo and 24 bovine) were diagnosed to have respiratory disease. In addition, 20 clinical- ly healthy calves (7 buffalo and 13 bovine) were randomly selected as a control group. Clinical and hematological exam- inations as well as measurement of haptoglobin (Hp), fibrin- ogen (Fb), IgG, IgA, total protein (TP), albumin, and globulin were carried out. Clinically, in acute respiratory disease, buf- falo calves had lower clinical index scores (p<0.05) than bovine calves. In both buffalo and bovine calves, Fb and Hp levels were increased significantly (p<0.05) in acute respira- tory disease compared with chronic cases. However, IgA, IgG, and albumin levels showed a significant decrease (p < 0.05). Moreover, buffalo calves had a significant increase (p < 0.05) of Hp and IgG compared with bovine calves. Total protein and globulin levels showed a significant decrease (p < 0.05) in calves with chronic respiratory diseases. In con- clusion, Hp and IgG response in buffalo calves with respira- tory disease seems to differ from bovine calves. Further stud- ies need to be done on experimental respiratory infection in buffalo calves to elucidate the specific acute-phase response.

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April 2014
22 Reads

Top co-authors

Ikuo Igarashi
Ikuo Igarashi

National Research Center for Protozoan Diseases

16
Naoaki Yokoyama
Naoaki Yokoyama

National Research Center for Protozoan Diseases

12
Mahmoud Aboulaila
Mahmoud Aboulaila

National Research Center for Protozoan Diseases

5
Azirwan Guswanto
Azirwan Guswanto

Obihiro University of Agriculture and Veterinary Medicine

5
Thillaiampalam Sivakumar
Thillaiampalam Sivakumar

Obihiro University of Agriculture and Veterinary Medicine

5
Xuenan Xuan
Xuenan Xuan

Obihiro University of Agriculture and Veterinary Medicine

4
Dickson Stuart Tayebwa
Dickson Stuart Tayebwa

Central Diagnostic Laboratory

4
Arifin Budiman Nugraha
Arifin Budiman Nugraha

National Research Center for Protozoan Diseases

4

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