Miwa Sasai

Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, Japan; Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan.. Electronic address:

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April 2020

Initial phospholipid-dependent Irgb6 targeting to vacuoles mediates host defense.

Authors:

Youngae Lee Hiroshi Yamada Ariel Pradipta Ji Su Ma Masaaki Okamoto Hikaru Nagaoka Eizo Takashima Daron M Standley Miwa Sasai Kohji Takei Masahiro Yamamoto

Life Sci Alliance 2020 01 18;3(1). Epub 2019 Dec 18.

Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan

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January 2020

Innate, adaptive, and cell-autonomous immunity against Toxoplasma gondii infection.

Authors:

Miwa Sasai Masahiro Yamamoto

Exp Mol Med 2019 12 11;51(12):1-10. Epub 2019 Dec 11.

Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.

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December 2019

CXCR4 regulates development in mouse and human hepatocytes.

Authors:

Hironori Bando Ariel Pradipta Shiroh Iwanaga Toru Okamoto Daisuke Okuzaki Shun Tanaka Joel Vega-Rodríguez Youngae Lee Ji Su Ma Naoya Sakaguchi Akira Soga Shinya Fukumoto Miwa Sasai Yoshiharu Matsuura Masao Yuda Marcelo Jacobs-Lorena Masahiro Yamamoto

J Exp Med 2019 08 12;216(8):1733-1748. Epub 2019 Jun 12.

Department of Immunoparasitology, Osaka University, Osaka, Japan

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August 2019

Effector GRA15-Dependent Suppression of IFN-γ-Induced Antiparasitic Response in Human Neurons.

Authors:

Hironori Bando Youngae Lee Naoya Sakaguchi Ariel Pradipta Ryoma Sakamoto Shun Tanaka Ji Su Ma Miwa Sasai Masahiro Yamamoto

Front Cell Infect Microbiol 2019 1;9:140. Epub 2019 May 1.

Department of Immunoparasitology, Research Institute for Microbial Diseases, Suita, Japan.

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January 2020

GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections.

Authors:

Jin Kyung Kim Yi Sak Kim Hye-Mi Lee Hyo Sun Jin Chiranjivi Neupane Sup Kim Sang-Hee Lee Jung-Joon Min Miwa Sasai Jae-Ho Jeong Seong-Kyu Choe Jin-Man Kim Masahiro Yamamoto Hyon E Choy Jin Bong Park Eun-Kyeong Jo

Nat Commun 2018 10 10;9(1):4184. Epub 2018 Oct 10.

Department of Microbiology, Chungnam National University School of Medicine, Daejeon, 35015, Korea.

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October 2018

Inducible Nitric Oxide Synthase Is a Key Host Factor for GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human Response.

Authors:

Hironori Bando Youngae Lee Naoya Sakaguchi Ariel Pradipta Ji Su Ma Shun Tanaka Yihong Cai Jianfa Liu Jilong Shen Yoshifumi Nishikawa Miwa Sasai Masahiro Yamamoto

mBio 2018 10 9;9(5). Epub 2018 Oct 9.

Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka, Japan

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October 2018

Effector TgIST Targets Host IDO1 to Antagonize the IFN-γ-Induced Anti-parasitic Response in Human Cells.

Authors:

Hironori Bando Naoya Sakaguchi Youngae Lee Ariel Pradipta Ji Su Ma Shun Tanaka De-Hua Lai Jianfa Liu Zhao-Rong Lun Yoshifumi Nishikawa Miwa Sasai Masahiro Yamamoto

Front Immunol 2018 19;9:2073. Epub 2018 Sep 19.

Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.

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September 2019

Host immune responses to Toxoplasma gondii.

Authors:

Miwa Sasai Ariel Pradipta Masahiro Yamamoto

Int Immunol 2018 03;30(3):113-119

Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, Yamadaoka, Suita, Osaka, Japan.

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March 2018

Characterization of SPP inhibitors suppressing propagation of HCV and protozoa.

Authors:

Junki Hirano Toru Okamoto Yukari Sugiyama Tatsuya Suzuki Shinji Kusakabe Makoto Tokunaga Takasuke Fukuhara Miwa Sasai Takahiro Tougan Yasue Matsunaga Kazuo Yamashita Yusuke Sakai Masahiro Yamamoto Toshihiro Horii Daron M Standley Kohji Moriishi Kyoji Moriya Kazuhiko Koike Yoshiharu Matsuura

Proc Natl Acad Sci U S A 2017 12 29;114(50):E10782-E10791. Epub 2017 Nov 29.

Department of Molecular Virology, Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan;

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December 2017

Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.

Authors:

Miwa Sasai Naoya Sakaguchi Ji Su Ma Shuhei Nakamura Tsuyoshi Kawabata Hironori Bando Youngae Lee Tatsuya Saitoh Shizuo Akira Akiko Iwasaki Daron M Standley Tamotsu Yoshimori Masahiro Yamamoto

Nat Immunol 2017 Aug 12;18(8):899-910. Epub 2017 Jun 12.

Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.

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August 2017

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.

Authors:

Si Ming Man Rajendra Karki Miwa Sasai David E Place Sannula Kesavardhana Jamshid Temirov Sharon Frase Qifan Zhu R K Subbarao Malireddi Teneema Kuriakose Jennifer L Peters Geoffrey Neale Scott A Brown Masahiro Yamamoto Thirumala-Devi Kanneganti

Cell 2016 Oct 29;167(2):382-396.e17. Epub 2016 Sep 29.

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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October 2016

The P2X4 receptor is required for neuroprotection via ischemic preconditioning.

Authors:

Tomohiko Ozaki Rieko Muramatsu Miwa Sasai Masahiro Yamamoto Yoshiaki Kubota Toshiyuki Fujinaka Toshiki Yoshimine Toshihide Yamashita

Sci Rep 2016 05 13;6:25893. Epub 2016 May 13.

Department of Molecular Neuroscience, Graduate School of Medicine, Osaka University, 2-2 Yamada-oka, Suita, Osaka 565-0871, Japan.

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May 2016

p62 Plays a Specific Role in Interferon-γ-Induced Presentation of a Toxoplasma Vacuolar Antigen.

Authors:

Youngae Lee Miwa Sasai Ji Su Ma Naoya Sakaguchi Jun Ohshima Hironori Bando Tatsuya Saitoh Shizuo Akira Masahiro Yamamoto

Cell Rep 2015 Oct 1;13(2):223-33. Epub 2015 Oct 1.

Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan; Laboratory of Immunoparasitology, WPI Immunology Frontier Research Center, Osaka University, 3-1 Yamada-oka, Suita, Osaka 565-0871, Japan. Electronic address:

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October 2015

RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii.

Authors:

Jun Ohshima Miwa Sasai Jianfa Liu Kazuo Yamashita Ji Su Ma Youngae Lee Hironori Bando Jonathan C Howard Shigeyuki Ebisu Mikako Hayashi Kiyoshi Takeda Daron M Standley Eva-Maria Frickel Masahiro Yamamoto

Proc Natl Acad Sci U S A 2015 Aug 3;112(33):E4581-90. Epub 2015 Aug 3.

Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan 5650871; Laboratory of Immunoparasitology, World Premier International Research Center Immunology Frontier Research Center, Osaka University, Osaka, Japan 5650871;

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August 2015

Toll-like receptor 9 trafficking and signaling for type I interferons requires PIKfyve activity.

Authors:

Kachiko Hayashi Miwa Sasai Akiko Iwasaki

Int Immunol 2015 Sep 29;27(9):435-45. Epub 2015 Apr 29.

Howard Hughes Medical Institute, Department of Immunobiology, Yale University School of Medicine, 300 Cedar Street, TAC S655B, New Haven, CT 06520, USA

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September 2015

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