Mitzi I Kuroda

Mitzi I Kuroda

UNVERIFIED PROFILE

Are you Mitzi I Kuroda?   Register this Author

Register author
Mitzi I Kuroda

Mitzi I Kuroda

Publications by authors named "Mitzi I Kuroda"

Are you Mitzi I Kuroda?   Register this Author

58Publications

1118Reads

50Profile Views

Combination Targeting of the Bromodomain and Acetyltransferase Active Site of p300/CBP.

Biochemistry 2019 Apr 11;58(16):2133-2143. Epub 2019 Apr 11.

Division of Genetics, Department of Medicine , Brigham and Women's Hospital , Boston , Massachusetts 02115 , United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.biochem.9b00160DOI Listing
April 2019

"Z4" Complex Member Fusions in NUT Carcinoma: Implications for a Novel Oncogenic Mechanism.

Mol Cancer Res 2018 12 23;16(12):1826-1833. Epub 2018 Aug 23.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-18-0474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279489PMC
December 2018

Sex-specific phenotypes of histone H4 point mutants establish dosage compensation as the critical function of H4K16 acetylation in .

Proc Natl Acad Sci U S A 2018 12 10;115(52):13336-13341. Epub 2018 Dec 10.

Laboratory of Chromatin Biology, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1817274115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310812PMC
December 2018

Bivalent complexes of PRC1 with orthologs of BRD4 and MOZ/MORF target developmental genes in .

Genes Dev 2017 10 25;31(19):1988-2002. Epub 2017 Oct 25.

Division of Genetics, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.305987.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710143PMC
October 2017

The Oncoprotein BRD4-NUT Generates Aberrant Histone Modification Patterns.

PLoS One 2016 3;11(10):e0163820. Epub 2016 Oct 3.

Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0163820PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047744PMC
June 2017

, the homologue of SET3, Is Required for Viability and the Proper Balance of Active and Repressive Chromatin Marks.

G3 (Bethesda) 2017 02 9;7(2):625-635. Epub 2017 Feb 9.

Division of Genetics, Brigham and Women's Hospital, Boston, Massachusetts 02115

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1534/g3.116.037788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295607PMC
February 2017

Correspondence of Drosophila polycomb group proteins with broad H3K27me3 silent domains.

Fly (Austin) 2015 ;9(4):178-82

b Division of Genetics; Brigham and Women's Hospital ; Boston , MA 02115.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/19336934.2016.1151988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862425PMC
December 2016

Dosage Compensation in Drosophila-a Model for the Coordinate Regulation of Transcription.

Genetics 2016 Oct;204(2):435-450

Department of Biology, O. Wayne Rollins Research Center, Emory University, Atlanta, Georgia 30322.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1534/genetics.115.185108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068838PMC
October 2016

Streamlined discovery of cross-linked chromatin complexes and associated histone modifications by mass spectrometry.

Proc Natl Acad Sci U S A 2016 Feb 1;113(7):1784-9. Epub 2016 Feb 1.

Division of Genetics, Brigham and Women's Hospital, Boston, MA 02115; Department of Genetics, Harvard Medical School, Boston, MA 02115;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1522750113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763777PMC
February 2016

The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains.

Genes Dev 2015 Jul;29(14):1507-23

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.267583.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526735PMC
July 2015

Sex comb on midleg (Scm) is a functional link between PcG-repressive complexes in Drosophila.

Genes Dev 2015 Jun;29(11):1136-50

Division of Genetics, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.260562.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470282PMC
June 2015

Dosage compensation in Drosophila.

Cold Spring Harb Perspect Biol 2015 May 1;7(5). Epub 2015 May 1.

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/cshperspect.a019398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448616PMC
May 2015

BioTAP-XL: Cross-linking/Tandem Affinity Purification to Study DNA Targets, RNA, and Protein Components of Chromatin-Associated Complexes.

Curr Protoc Mol Biol 2015 Jan 5;109:21.30.1-21.30.32. Epub 2015 Jan 5.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/0471142727.mb2130s109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308290PMC
January 2015

Comparative analysis of metazoan chromatin organization.

Nature 2014 Aug;512(7515):449-52

1] Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts 02115, USA [2] Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA [3] Informatics Program, Children's Hospital, Boston, Massachusetts 02215, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature13415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227084PMC
August 2014

Heterochromatin-associated interactions of Drosophila HP1a with dADD1, HIPP1, and repetitive RNAs.

Genes Dev 2014 Jul;28(13):1445-60

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA;

View Article

Download full-text PDF

Source
http://genesdev.cshlp.org/cgi/doi/10.1101/gad.241950.114
Publisher Site
http://dx.doi.org/10.1101/gad.241950.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4083088PMC
July 2014

Impact of sequencing depth in ChIP-seq experiments.

Nucleic Acids Res 2014 May 5;42(9):e74. Epub 2014 Mar 5.

Center for Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA Division of Genetics, Brigham and Women's Hospital & Harvard Medical School, Boston, MA 02115, USA Informatics Program, Children's Hospital, Boston, MA 02115, USA

View Article

Download full-text PDF

Source
http://nar.oxfordjournals.org/content/42/9/e74.full.pdf
Web Search
https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
Publisher Site
http://dx.doi.org/10.1093/nar/gku178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027199PMC
May 2014

Are we there yet? Initial targeting of the Male-Specific Lethal and Polycomb group chromatin complexes in Drosophila.

Open Biol 2014 Mar 26;4:140006. Epub 2014 Mar 26.

Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1098/rsob.140006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971409PMC
March 2014

Transcriptional control of a whole chromosome: emerging models for dosage compensation.

Nat Struct Mol Biol 2014 Feb 5;21(2):118-25. Epub 2014 Feb 5.

1] Department of Medicine, Division of Genetics, Brigham and Women's Hospital, Boston, Massachusetts, USA. [2] Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nsmb.2763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342042PMC
February 2014

Reciprocal interactions of human C10orf12 and C17orf96 with PRC2 revealed by BioTAP-XL cross-linking and affinity purification.

Proc Natl Acad Sci U S A 2014 Feb 3;111(7):2488-93. Epub 2014 Feb 3.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.

View Article

Download full-text PDF

Source
http://www.pnas.org/cgi/doi/10.1073/pnas.1400648111
Publisher Site
http://dx.doi.org/10.1073/pnas.1400648111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932854PMC
February 2014

Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila.

Nat Struct Mol Biol 2013 Feb 6;20(2):202-9. Epub 2013 Jan 6.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nsmb.2477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674866PMC
February 2013

Identification of chromatin-associated regulators of MSL complex targeting in Drosophila dosage compensation.

PLoS Genet 2012 26;8(7):e1002830. Epub 2012 Jul 26.

Department of Molecular Biology, Cellular Biology, and Biochemistry, Brown University, Providence, Rhode Island, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1002830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405997PMC
January 2013

The genomic binding sites of a noncoding RNA.

Proc Natl Acad Sci U S A 2011 Dec 5;108(51):20497-502. Epub 2011 Dec 5.

Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1113536108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3251105PMC
December 2011

X chromosome dosage compensation via enhanced transcriptional elongation in Drosophila.

Nature 2011 Mar;471(7336):115-8

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nature09757
Publisher Site
http://dx.doi.org/10.1038/nature09757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076316PMC
March 2011

Evidence of activity-specific, radial organization of mitotic chromosomes in Drosophila.

PLoS Biol 2011 Jan 11;9(1):e1000574. Epub 2011 Jan 11.

Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pbio.1000574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019107PMC
January 2011

Identification of functional elements and regulatory circuits by Drosophila modENCODE.

Science 2010 Dec 22;330(6012):1787-97. Epub 2010 Dec 22.

Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.

View Article

Download full-text PDF

Source
http://compbio.mit.edu/publications/46_modENCODE_Science_10.
Web Search
http://www.sciencemag.org/cgi/doi/10.1126/science.1198374
Publisher Site
http://dx.doi.org/10.1126/science.1198374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3192495PMC
December 2010

Quantized correlation coefficient for measuring reproducibility of ChIP-chip data.

BMC Bioinformatics 2010 Jul 27;11:399. Epub 2010 Jul 27.

Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2105-11-399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919519PMC
July 2010

Long-range spreading of dosage compensation in Drosophila captures transcribed autosomal genes inserted on X.

Genes Dev 2009 Oct;23(19):2266-71

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.1840409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758747PMC
October 2009

Drosophila MSL complex globally acetylates H4K16 on the male X chromosome for dosage compensation.

Nat Struct Mol Biol 2009 Aug 2;16(8):825-32. Epub 2009 Aug 2.

Division of Genetics, Department of Medicine, Brigham & Women's Hospital, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nsmb.1644
Publisher Site
http://dx.doi.org/10.1038/nsmb.1644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722042PMC
August 2009

Variable splicing of non-coding roX2 RNAs influences targeting of MSL dosage compensation complexes in Drosophila.

RNA Biol 2005 Oct-Dec;2(4):157-64. Epub 2005 Dec 27.

Howard Hughes Medical Institute, Chevy Chase, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/rna.2.4.2473DOI Listing
July 2009

Drosophila dosage compensation: a complex voyage to the X chromosome.

Development 2009 May;136(9):1399-410

Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/dev.029645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674252PMC
May 2009

The MSL3 chromodomain directs a key targeting step for dosage compensation of the Drosophila melanogaster X chromosome.

Nat Struct Mol Biol 2008 Dec 23;15(12):1318-25. Epub 2008 Nov 23.

Harvard-Partners Center for Genetics and Genomics, Division of Genetics, Department of Medicine, Brigham & Women's Hospital, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nsmb.1520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636508PMC
December 2008

Regulation of histone H4 Lys16 acetylation by predicted alternative secondary structures in roX noncoding RNAs.

Mol Cell Biol 2008 Aug 9;28(16):4952-62. Epub 2008 Jun 9.

Department of Cell Biology and Molecular Medicine, UMDNJ-New Jersey Medical School, Newark, NJ 07103, USA.

View Article

Download full-text PDF

Source
http://mcb.asm.org/cgi/doi/10.1128/MCB.00219-08
Publisher Site
http://dx.doi.org/10.1128/MCB.00219-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519712PMC
August 2008

A sequence motif within chromatin entry sites directs MSL establishment on the Drosophila X chromosome.

Cell 2008 Aug;134(4):599-609

Harvard-Partners Center for Genetics and Genomics, Division of Genetics, Department of Medicine, Brigham & Women's Hospital, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2008.06.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2613042PMC
August 2008

MSL complex is attracted to genes marked by H3K36 trimethylation using a sequence-independent mechanism.

Mol Cell 2007 Oct;28(1):121-33

Howard Hughes Medical Institute, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2007.08.011DOI Listing
October 2007

Normalization and experimental design for ChIP-chip data.

BMC Bioinformatics 2007 Jun 25;8:219. Epub 2007 Jun 25.

Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2105-8-219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913544PMC
June 2007

Noncoding RNAs and intranuclear positioning in monoallelic gene expression.

Cell 2007 Feb;128(4):777-86

Howard Hughes Medical Institute, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2007.01.032DOI Listing
February 2007

Global regulation of X chromosomal genes by the MSL complex in Drosophila melanogaster.

Genes Dev 2005 Oct;19(19):2289-94

Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.1343705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1240037PMC
October 2005

Sequence-specific targeting of MSL complex regulates transcription of the roX RNA genes.

EMBO J 2004 Jul 1;23(14):2853-61. Epub 2004 Jul 1.

Program in Developmental Biology, Baylor College of Medicine, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.emboj.7600299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC514957PMC
July 2004

Multiple classes of MSL binding sites target dosage compensation to the X chromosome of Drosophila.

Curr Biol 2004 Mar;14(6):481-7

Interdepartmental Program in Cell and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cub.2004.03.004DOI Listing
March 2004

Molecular biology. Filling gaps in genome organization.

Science 2004 Feb;303(5661):1148-9

Howard Hughes Medical Institute, Harvard-Partners Center for Genetics & Genomics, Harvard Medical School, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1095356DOI Listing
February 2004

The MSL complex levels are critical for its correct targeting to the chromosomes in Drosophila melanogaster.

Chromosoma 2003 Oct 6;112(3):103-15. Epub 2003 Sep 6.

Institute of Cytology and Genetics, Siberian Division of Russian Academy of Sciences, 630090 Novosibirsk, Russia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00412-003-0249-1DOI Listing
October 2003

Functional redundancy within roX1, a noncoding RNA involved in dosage compensation in Drosophila melanogaster.

Genetics 2003 Jul;164(3):1003-14

Department of Human and Molecular Genetics, Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462637PMC
July 2003

Local spreading of MSL complexes from roX genes on the Drosophila X chromosome.

Genes Dev 2003 Jun;17(11):1334-9

Interdepartmental Program in Cell and Molecular Biology, Howard Hughes Medical Institute, Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.1082003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC196065PMC
June 2003

The Drosophila roX1 RNA gene can overcome silent chromatin by recruiting the male-specific lethal dosage compensation complex.

Genetics 2003 Jun;164(2):565-74

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462573PMC
June 2003

Sequence-specific targeting of Drosophila roX genes by the MSL dosage compensation complex.

Mol Cell 2003 Apr;11(4):977-86

Howard Hughes Medical Institute, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s1097-2765(03)00147-3DOI Listing
April 2003

Extent of chromatin spreading determined by roX RNA recruitment of MSL proteins.

Science 2002 Nov;298(5598):1620-3

Howard Hughes Medical Institute, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1076686DOI Listing
November 2002

Sex and the single chromosome.

Adv Genet 2002 ;46:1-24

Department of Biology, Tufts University, Medford, Massachusetts 02155, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0065-2660(02)46002-6DOI Listing
August 2002