Mitsuru Ishikawa

Mitsuru Ishikawa

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Publications by authors named "Mitsuru Ishikawa"

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A combinational treatment of carotenoids decreases Aβ secretion in human neurons via β-secretase inhibition.

Neurosci Res 2019 Oct 10. Epub 2019 Oct 10.

Department of Physiology, Keio University, School of Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neures.2019.10.006DOI Listing
October 2019

Involvement of SRF coactivator MKL2 in BDNF-mediated activation of the synaptic activity-responsive element in the Arc gene.

J Neurochem 2019 01 12;148(2):204-218. Epub 2018 Nov 12.

Laboratory of Molecular Neurobiology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.

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http://dx.doi.org/10.1111/jnc.14596DOI Listing
January 2019

Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent.

Nat Med 2018 10 20;24(10):1579-1589. Epub 2018 Aug 20.

Department of Physiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

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http://www.nature.com/articles/s41591-018-0140-5
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http://dx.doi.org/10.1038/s41591-018-0140-5DOI Listing
October 2018

Generation of D1-1 TALEN isogenic control cell line from Dravet syndrome patient iPSCs using TALEN-mediated editing of the SCN1A gene.

Stem Cell Res 2018 04 2;28:100-104. Epub 2018 Feb 2.

Central Research Institute for the Molecular Pathomechanisms of Epilepsy, Fukuoka University, Japan; Department of Pediatrics, School of Medicine, Fukuoka University, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2018.01.036DOI Listing
April 2018

Synaptic localisation of SRF coactivators, MKL1 and MKL2, and their role in dendritic spine morphology.

Sci Rep 2018 01 15;8(1):727. Epub 2018 Jan 15.

Laboratory of Molecular Neurobiology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.

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http://dx.doi.org/10.1038/s41598-017-18905-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768758PMC
January 2018

Rho signaling inhibitor, CCG-1423, inhibits axonal elongation and dendritic complexity of rat cortical neurons.

Biochem Biophys Res Commun 2017 10 19;492(3):474-479. Epub 2017 Aug 19.

Laboratory of Molecular Neurobiology, Graduate School of Medicine & Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.08.071DOI Listing
October 2017

Deltamethrin Increases Neurite Outgrowth in Cortical Neurons through Endogenous BDNF/TrkB Pathways.

Cell Struct Funct 2017 Oct 23;42(2):141-148. Epub 2017 Sep 23.

Department of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama.

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http://dx.doi.org/10.1247/csf.17015DOI Listing
October 2017

Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine.

Schizophr Res 2017 03 27;181:75-82. Epub 2016 Oct 27.

Department of Psychiatry, Osaka University Graduate School of Medicine, D3, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan; Molecular Research Center for Children's Mental Development, United Graduate School of Child Development, Osaka University, D3, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2016.10.012DOI Listing
March 2017

Transient α-helices in the disordered RPEL motifs of the serum response factor coactivator MKL1.

Sci Rep 2014 Jun 9;4:5224. Epub 2014 Jun 9.

Laboratory of Molecular Neurobiology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.

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http://dx.doi.org/10.1038/srep05224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048911PMC
June 2014

Cellular localization and dendritic function of rat isoforms of the SRF coactivator MKL1 in cortical neurons.

Neuroreport 2014 May;25(8):585-92

aLaboratory of Molecular Neurobiology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama bDepartment of Neurobiology and Behavior, Gunma University, Graduate School of Medicine, Maebashi cDivision of Pharmacology, Biological Safety Research Center, National Institute of Health Sciences, Tokyo, Japan dSolomon H. Snyder Department of Neuroscience, Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/WNR.0000000000000141DOI Listing
May 2014

Identification, expression and characterization of rat isoforms of the serum response factor (SRF) coactivator MKL1.

FEBS Open Bio 2013 7;3:387-93. Epub 2013 Sep 7.

Laboratory of Molecular Neurobiology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.

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http://doi.wiley.com/10.1016/j.fob.2013.09.001
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http://dx.doi.org/10.1016/j.fob.2013.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821035PMC
November 2013

Single-molecule photochemical reactions of Auger-ionized quantum dots.

Nano Rev 2011 13;2. Epub 2011 Oct 13.

Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, Kagawa, Japan.

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http://dx.doi.org/10.3402/nano.v2i0.6366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226428PMC
October 2012

Inhibition assay of yeast cell walls by plasmon resonance Rayleigh scattering and surface-enhanced Raman scattering imaging.

Langmuir 2012 Jun 6;28(24):8952-8. Epub 2012 Apr 6.

Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, Kagawa 761-0395, Japan.

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https://www.researchgate.net/profile/Manikantan_Kiran/public
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http://pubs.acs.org/doi/abs/10.1021/la3004245
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http://dx.doi.org/10.1021/la3004245DOI Listing
June 2012

FRET from quantum dots to photodecompose undesired acceptors and report the condensation and decondensation of plasmid DNA.

ACS Nano 2012 May 10;6(5):3776-88. Epub 2012 Apr 10.

Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 2217-14 Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1021/nn2048608DOI Listing
May 2012

Luminescent quantum dots, making invisibles visible in bioimaging.

Prog Mol Biol Transl Sci 2011 ;104:53-99

National Institute of Advanced Industrial Science and Technology (AIST), Hayashi-cho, Takamatsu, Kagawa, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/B97801241602000
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http://dx.doi.org/10.1016/B978-0-12-416020-0.00002-4DOI Listing
March 2012

Deltamethrin, a type II pyrethroid insecticide, has neurotrophic effects on neurons with continuous activation of the Bdnf promoter.

Neuropharmacology 2012 Feb 7;62(2):1091-8. Epub 2011 Nov 7.

Department of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.

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http://dx.doi.org/10.1016/j.neuropharm.2011.10.023DOI Listing
February 2012

Photofabrication of fullerene-shelled quantum dots supramolecular nanoparticles for solar energy harvesting.

ACS Nano 2012 Feb 30;6(2):1601-8. Epub 2012 Jan 30.

Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, Kagawa 761-0395, Japan.

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http://www.ugcfrp.ac.in/images/userfiles/39631-Shibu-ACS%20N
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http://pubs.acs.org/doi/abs/10.1021/nn204567d
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http://dx.doi.org/10.1021/nn204567dDOI Listing
February 2012

How environmental solution conditions determine the compaction velocity of single DNA molecules.

Nucleic Acids Res 2012 Jan 6;40(1):284-9. Epub 2011 Sep 6.

Health Research Institute, National Institute of Advanced Industrial Science and Technology, Hayashi-cho, Takamatsu, Kagawa, 761-0395, Japan.

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http://dx.doi.org/10.1093/nar/gkr712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245929PMC
January 2012

Quantitative evaluation of blinking in surface enhanced resonance Raman scattering and fluorescence by electromagnetic mechanism.

J Chem Phys 2012 Jan;136(2):024703

Nano-bioanalysis Research Group, Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1063/1.3675567DOI Listing
January 2012

Characterization of DNA polymerase β from Danio rerio by overexpression in E. coli using the in vivo/in vitro compatible pIVEX plasmid.

Microb Cell Fact 2011 Oct 21;10:84. Epub 2011 Oct 21.

Health Research Institute, National Institute of Advanced Industrial Science and Technology, Takamatsu, Kagawa, Japan.

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http://microbialcellfactories.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/1475-2859-10-84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214136PMC
October 2011

Hybrid optical tweezers for dynamic micro-bead arrays.

Opt Express 2011 Aug;19(16):15445-51

National Institute of Advanced Industrial Science and Technology, Takamatsu 761-0395, Japan.

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http://dx.doi.org/10.1364/OE.19.015445DOI Listing
August 2011

Quantitative analysis of condensation/decondensation status of pDNA in the nuclear sub-domains by QD-FRET.

Nucleic Acids Res 2011 Apr 1;39(7):e48. Epub 2011 Feb 1.

Laboratory for Molecular Design of Pharmaceutics, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan.

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http://dx.doi.org/10.1093/nar/gkq1327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074156PMC
April 2011

Internal reflection ellipsometry in air and water ambient.

Opt Lett 2010 Dec;35(24):4226-8

Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Hayashi-cho, Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1364/ol.35.004226DOI Listing
December 2010

Consecutive incorporation of fluorophore-labeled nucleotides by mammalian DNA polymerase beta.

Anal Biochem 2010 Oct 4;405(2):160-7. Epub 2010 Jun 4.

Nano-Bioanalysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1016/j.ab.2010.06.005DOI Listing
October 2010

Highly sensitive detection of monosaccharides on microchip electrophoresis using pH discontinuous solution system.

Anal Sci 2010 ;26(7):731-6

Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), 2217-14 Hayashi, Takamatsu 761-0395, Japan.

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http://dx.doi.org/10.2116/analsci.26.731DOI Listing
October 2010

Involvement of the serum response factor coactivator megakaryoblastic leukemia (MKL) in the activin-regulated dendritic complexity of rat cortical neurons.

J Biol Chem 2010 Oct 13;285(43):32734-43. Epub 2010 Aug 13.

Department of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.

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http://dx.doi.org/10.1074/jbc.M110.118745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963415PMC
October 2010

Wavelength-scanning surface plasmon resonance imaging for label-free multiplexed protein microarray assay.

Biosens Bioelectron 2010 Sep 30;26(1):202-6. Epub 2010 Jun 30.

Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Hayashi-cho, Takamatsu 761-0395, Japan.

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http://dx.doi.org/10.1016/j.bios.2010.06.017DOI Listing
September 2010

Spectral variations in background light emission of surface-enhanced resonance hyper Raman scattering coupled with plasma resonance of individual silver nanoaggregates.

J Chem Phys 2010 Sep;133(12):124704

Nano-Bioanalysis Group, Health Technology Research Institute (HTRI), National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, Kagawa 761-0395, Japan.

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http://aip.scitation.org/doi/10.1063/1.3489920
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http://dx.doi.org/10.1063/1.3489920DOI Listing
September 2010

Delivering quantum dots to cells: bioconjugated quantum dots for targeted and nonspecific extracellular and intracellular imaging.

Chem Soc Rev 2010 Aug 27;39(8):3031-56. Epub 2010 May 27.

Health Research Institute, National Institute of Advanced Industrial Science and Technology, 2217-14 Hayashi-Cho, Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1039/b926512kDOI Listing
August 2010

Blinking suppression in CdSe/ZnS single quantum dots by TiO2 nanoparticles.

ACS Nano 2010 Aug;4(8):4445-54

Nano-bioanalysis Group, Health Research Institute, National Institute of Advanced Industrial Science and Technology, 2217-14 Hayashi-Cho, Takamatsu, Kagawa 761-0396, Japan.

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http://pubs.acs.org/doi/10.1021/nn100698u
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http://dx.doi.org/10.1021/nn100698uDOI Listing
August 2010

Bioconjugated quantum dots for cancer research: present status, prospects and remaining issues.

Biotechnol Adv 2010 Mar-Apr;28(2):199-213. Epub 2009 Dec 5.

Nanobioanalysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, 2217-14 Hayashi-Cho, Takamatsu, Kagawa 761-0395, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S07349750090019
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http://dx.doi.org/10.1016/j.biotechadv.2009.11.007DOI Listing
June 2010

Analysis of supercoiled DNA by agarose gel electrophoresis using low-conducting sodium threonine medium.

Anal Biochem 2010 May 18;400(1):148-50. Epub 2010 Jan 18.

Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1016/j.ab.2010.01.020DOI Listing
May 2010

Selective detection of HbA1c using surface enhanced resonance Raman spectroscopy.

Anal Chem 2010 Feb;82(4):1342-8

Nanobioanalysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1021/ac902364hDOI Listing
February 2010

Reversible dimerization of EGFR revealed by single-molecule fluorescence imaging using quantum dots.

Chemistry 2010 Jan;16(4):1186-92

Health Technology Research Center, National Institute of Advanced Industrial, Science and Technology (AIST), 2217-14 Hayashi-Cho, Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1002/chem.200902963DOI Listing
January 2010

Carbohydrate-protein interactions investigated on plastic chips statically coated with hydrophobically modified hydroxyethylcellulose.

Anal Chem 2009 Dec;81(24):10055-60

Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, Hayashi-cho 2217-14, Takamatsu 761-0395, Japan.

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http://dx.doi.org/10.1021/ac902014cDOI Listing
December 2009

Dynamic micro-bead arrays using optical tweezers combined with intelligent control techniques.

Opt Express 2009 Dec;17(26):24102-11

National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, 761-0395, Japan.

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http://dx.doi.org/10.1364/OE.17.024102DOI Listing
December 2009

Laser-induced self-assembly of silver nanoparticles via plasmonic interactions.

Opt Express 2009 Oct;17(21):18760-7

Department of Applied Physics, Osaka University, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1364/OE.17.018760DOI Listing
October 2009

Spontaneous adsorption on a hydrophobic surface governed by hydrogen bonding.

Langmuir 2009 Aug;25(16):9296-301

Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Hayashi-cho 2217-14, Takamatsu 761-0395, Japan.

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http://dx.doi.org/10.1021/la900850uDOI Listing
August 2009

Clathrin-mediated endocytosis of quantum dot-peptide conjugates in living cells.

ACS Nano 2009 Aug;3(8):2419-29

Nanobioanalysis Team and Glycolipid Function Analysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), 2217-14 Hayashi-Cho, Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1021/nn900663rDOI Listing
August 2009

Rapid sequencing gel electrophoresis using glycerol-tolerant sodium taurine medium.

Anal Biochem 2009 Jul 11;390(1):100-1. Epub 2009 Apr 11.

Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1016/j.ab.2009.04.006DOI Listing
July 2009

Evaluation of electromagnetic enhancement of surface enhanced hyper Raman scattering using plasmonic properties of binary active sites in single Ag nanoaggregates.

J Chem Phys 2009 Jun;130(21):214706

Nano-Bioanalysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1063/1.3146788DOI Listing
June 2009

Measuring the length distribution of self-assembled lipid nanotubes by orientation control with a high-frequency alternating current electric field in aqueous solutions.

Anal Chem 2009 Feb;81(4):1459-64

Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, 2217-14, Hayashi-cho, Takamatsu, Kagawa, 761-0395, Japan.

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http://pubs.acs.org/doi/abs/10.1021/ac8022795
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http://dx.doi.org/10.1021/ac8022795DOI Listing
February 2009

Dependence of luminescence efficiency of cdse quantum dots on chemical environments.

J Nanosci Nanotechnol 2008 Nov;8(11):5615-23

NUS Nanoscience and Nanotechnology Initiative, National University of Singapore, Singapore-117576.

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November 2008

Automated manipulation of non-spherical micro-objects using optical tweezers combined with image processing techniques.

Opt Express 2008 Sep;16(19):15115-22

National Institute of Advanced Industrial Science and Technology, Takamatsu 761-0395, Japan.

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http://dx.doi.org/10.1364/oe.16.015115DOI Listing
September 2008

Use of a heterogeneous buffer combination in microchip electrophoresis for high-resolution separation by on-line concentration of DNA samples.

Electrophoresis 2008 Sep;29(18):3744-51

Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, 2217-14 Hayashi-cho, Takamatsu, Kagawa, Japan.

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http://dx.doi.org/10.1002/elps.200800143DOI Listing
September 2008

Semiconductor quantum dots and metal nanoparticles: syntheses, optical properties, and biological applications.

Anal Bioanal Chem 2008 Aug 12;391(7):2469-95. Epub 2008 Jun 12.

Nano-Bioanalysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), 2217-14 Hayashi-cho, Takamatsu, Kagawa, 761-0395, Japan.

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http://dx.doi.org/10.1007/s00216-008-2185-7DOI Listing
August 2008

Photosensitized breakage and damage of DNA by CdSe-ZnS quantum dots.

J Phys Chem B 2008 Aug 26;112(32):10005-11. Epub 2008 Jun 26.

Nanobioanalysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, 2217-14 Hayashi-cho, Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1021/jp8018606DOI Listing
August 2008

Enhancing fluorescence detection with a photonic crystal structure in a total-internal-reflection configuration.

Opt Lett 2008 Aug;33(15):1729-31

Center for Ultrafast Optical Science, University of Michigan, 2200 Bonisteel Boulevard, Ann Arbor, Michigan 48109-2099, USA.

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http://dx.doi.org/10.1364/ol.33.001729DOI Listing
August 2008

Sizing of single globular DNA molecules by using a circular acceleration technique with laser trapping.

Anal Chem 2008 Jul 20;80(13):5197-202. Epub 2008 May 20.

Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, 2217-14, Hayashi-cho, Takamatsu, Kagawa, 761-0395, Japan.

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http://dx.doi.org/10.1021/ac8003538DOI Listing
July 2008

Quantum dot-insect neuropeptide conjugates for fluorescence imaging, transfection, and nucleus targeting of living cells.

Langmuir 2007 Sep 24;23(20):10254-61. Epub 2007 Aug 24.

Nano-bioanalysis Team and Glycolipid Function Analysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, 2217-14 Hayashi-cho, Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1021/la7012705DOI Listing
September 2007

Gene expression profile in squamous cell carcinoma of the urinary bladder using complementary deoxyribonucleic acid microarray.

Urol Oncol 2007 Mar-Apr;25(2):120-7

Health Technology Research Center, National Institute of Advanced Industrial Science and Technology Shikoku, Takamatsu, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S107814390600093
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http://dx.doi.org/10.1016/j.urolonc.2006.03.006DOI Listing
May 2007

Usefulness of the 5' region of the cDNA encoding acidic ribosomal phosphoprotein P0 conserved among rats, mice, and humans as a standard probe for gene expression analysis in different tissues and animal species.

J Biochem Biophys Methods 2007 Apr 28;70(3):481-6. Epub 2006 Nov 28.

Institute for Genome Research, Faculty of Pharmaceutical Sciences, University of Tokushima, Kuramotocho-3, Tokushima 770-8503, Japan.

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http://dx.doi.org/10.1016/j.jbbm.2006.11.008DOI Listing
April 2007

Polarization modulation imaging ellipsometer.

Opt Lett 2007 Jan;32(2):130-2

Health Technology Research Center., National Institute of Advanced Industrial Science and Technology, Kagawa, Japan.

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http://dx.doi.org/10.1364/ol.32.000130DOI Listing
January 2007

Quenching of photoluminescence in conjugates of quantum dots and single-walled carbon nanotube.

J Phys Chem B 2006 Dec;110(51):26068-74

Nano-Bioanalysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), 2217-14 Hayashi-cho, Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1021/jp0657890DOI Listing
December 2006

Variations in steady-state and time-resolved background luminescence from surface-enhanced resonance Raman scattering-active single Ag nanoaggregates.

J Phys Chem B 2006 Nov;110(43):21536-44

Nano-Bioanalysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), 2217-14 Hayashi-cho, Takamatsu Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1021/jp064070pDOI Listing
November 2006

Developmental expression of the SRF co-activator MAL in brain: role in regulating dendritic morphology.

J Neurochem 2006 Sep;98(6):1778-88

Department of Biological Chemistry, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama City, Japan.

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http://doi.wiley.com/10.1111/j.1471-4159.2006.03992.x
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http://dx.doi.org/10.1111/j.1471-4159.2006.03992.xDOI Listing
September 2006

Surfactant protein B gene variations and susceptibility to lung cancer in chromate workers.

Am J Ind Med 2006 May;49(5):367-73

Single-Molecule Bioanalysis Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), Takamatsu, Japan.

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http://dx.doi.org/10.1002/ajim.20283DOI Listing
May 2006

Surface-enhanced resonance Raman scattering and background light emission coupled with plasmon of single Ag nanoaggregates.

J Chem Phys 2006 Apr;124(13):134708

Nano-Bioanalysis Team, Health Technology Research Center, National Institute for Advanced Industrial Science and Technology, Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1063/1.2177662DOI Listing
April 2006

Rapid analysis of oligosaccharides derived from glycoproteins by microchip electrophoresis.

J Chromatogr A 2006 Mar 27;1109(2):138-43. Epub 2005 Dec 27.

Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Hayashi-cho 2217-14, Takamatsu 761-0395, Japan.

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http://dx.doi.org/10.1016/j.chroma.2005.11.133DOI Listing
March 2006

Hybrid dynamic coating with n-dodecyl beta-D-maltoside and methyl cellulose for high-performance carbohydrate analysis on poly(methyl methacrylate) chips.

Anal Chem 2006 Mar;78(5):1452-8

Nano-bioanalysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Hayashi-cho 2217-14, Takamatsu 761-0395, Japan.

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http://pubs.acs.org/doi/abs/10.1021/ac051702f
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http://dx.doi.org/10.1021/ac051702fDOI Listing
March 2006

Self-surface passivation of CdX (X = Se, Te) quantum dots.

J Nanosci Nanotechnol 2006 Mar;6(3):618-23

Nano-Bioanalysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Hayashi-cho 2217-14, Takamatsu 761-0395, Japan.

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http://dx.doi.org/10.1166/jnn.2006.112DOI Listing
March 2006

Structure-property correlation of CdSe clusters using experimental results and first-principles DFT calculations.

J Am Chem Soc 2006 Jan;128(2):629-36

Nano-bioanalysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, Takamatsu, Kagawa, Japan.

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http://pubs.acs.org/doi/abs/10.1021/ja0565018
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January 2006

Ultrafast diagnosis of the genetic-related disorders using the combined technologies of multiplex PCR and multichannel microchip electrophoresis.

Anal Sci 2005 Dec;21(12):1537-9

Department of Applied Chemistry, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.

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http://dx.doi.org/10.2116/analsci.21.1537DOI Listing
December 2005

Nonradioactive telomerase activity assay by microchip electrophoresis: privileges to the classical gel electrophoresis assay.

Electrophoresis 2005 Aug;26(15):3021-4

Single-Molecule Bioanalysis Laboratory (SMBL), National Institute for Advanced Industrial Science and Technology, AIST-Shikoku, Takamatsu, Japan.

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http://dx.doi.org/10.1002/elps.200410435DOI Listing
August 2005

Subsecond luminescence intensity fluctuations of single CdSe quantum dots.

J Phys Chem B 2005 Aug;109(30):14350-5

Nano-Bioanalysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), 2217-14 Hayashi-cho, Takamatsu Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1021/jp0526187DOI Listing
August 2005

Temperature-sensitive photoluminescence of CdSe quantum dot clusters.

J Phys Chem B 2005 Jul;109(29):13899-905

Nano-Bioanalysis Team, Health Technology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), 2217-14 Hayashi-cho, Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1021/jp050424lDOI Listing
July 2005

Role of free cadmium and selenium ions in the potential mechanism for the enhancement of photoluminescence of CdSe quantum dots under ultraviolet irradiation.

J Nanosci Nanotechnol 2005 Jun;5(6):887-94

Single-Molecule Bioanalysis Laboratory, National Institute for Advanced Industrial Science and Technology, AIST-Shikoku, 2217-14 Hayashi-Cho, Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1166/jnn.2005.117DOI Listing
June 2005

A history of microarrays in biomedicine.

Expert Rev Mol Diagn 2005 May;5(3):315-28

Single-Molecule Bioanalysis Laboratory, National Institute of Advanced Industrial Science & Technology (AIST), Hayashi-cho 2217-14, Takamatsu City, Kagawa Prefecture, 761-0395 Japan.

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http://dx.doi.org/10.1586/14737159.5.3.315DOI Listing
May 2005

High-performance genetic analysis on microfabricated capillary array electrophoresis plastic chips fabricated by injection molding.

Anal Chem 2005 Apr;77(7):2140-6

Single-Molecule Bioanalysis Laboratory, National Institute of Advanced Industrial Science and Technology (AIST), Hayashi-cho 2217-14, Takamatsu 761-0395, Japan.

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http://dx.doi.org/10.1021/ac0485031DOI Listing
April 2005

Fabrication of quantum dot-lectin conjugates as novel fluorescent probes for microscopic and flow cytometric identification of leukemia cells from normal lymphocytes.

Chem Commun (Camb) 2005 Apr 24(15):1980-2. Epub 2005 Feb 24.

Single-Molecule Bioanalysis Laboratory, AIST-Shikoku, 2217-14, Hayashi-cho, Takamatsu, Kagawa-ken, Japan.

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http://xlink.rsc.org/?DOI=B419305A
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http://dx.doi.org/10.1039/b419305aDOI Listing
April 2005

Quantum dots as photosensitizers?

Nat Biotechnol 2004 Nov;22(11):1360-1

Single-Molecule Bioanalysis Laboratory, National Institute for Advanced Industrial Science and Technology, 2217-14 Hayashi-cho, Takamatsu 761-0395, Japan.

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http://dx.doi.org/10.1038/nbt1104-1360DOI Listing
November 2004

Inhibition of bcr-abl and/or c-abl gene expression by small interfering, double-stranded RNAs: cross-talk with cell proliferation factors and other oncogenes.

Cancer 2004 Sep;101(6):1390-403

Single-Molecule Bioanalysis Laboratory, National Institute for Advanced Industrial Science and Technology, Takamatsu, Kagawa, Japan.

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http://doi.wiley.com/10.1002/cncr.20468
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September 2004

Atypical protein-kinase Czeta, but neither conventional Ca2+ -dependent protein-kinase C isoenzymes nor Ca2+ -calmodulin, participates in regulation of telomerase activity in Burkitt's lymphoma cells.

Cancer Chemother Pharmacol 2004 Aug 23;54(2):161-72. Epub 2004 Apr 23.

Single-Molecule Bioanalysis Laboratory, National Institute for Advanced Industrial Science and Technology-Shikoku, 2217-14 Hayashi-cho, Kagawa-ken, Takamatsu, Japan.

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http://dx.doi.org/10.1007/s00280-004-0789-yDOI Listing
August 2004

[Physical mapping of single-molecule DNA structures].

Authors:
Mitsuru Ishikawa

Tanpakushitsu Kakusan Koso 2004 Aug;49(11 Suppl):1490-4

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August 2004

Enhancement of the photoluminescence of CdSe quantum dots during long-term UV-irradiation: privilege or fault in life science research?

J Photochem Photobiol B 2004 Jul;75(1-2):99-105

Natural-Substance Composed Materials Group, National Institute for Advanced Industrial Science and Technology, AIST-Kyushu, Tosu, Saga-ken, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S101113440400064
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http://dx.doi.org/10.1016/j.jphotobiol.2004.05.014DOI Listing
July 2004

Suppression of bcr-abl synthesis by siRNAs or tyrosine kinase activity by Glivec alters different oncogenes, apoptotic/antiapoptotic genes and cell proliferation factors (microarray study).

FEBS Lett 2004 Jul;570(1-3):195-204

Single-Molecule Bioanalysis Laboratory, National Institute for Advanced Industrial Science and Technology, AIST-Shikoku, 2217-14 Hayashi-cho, Takamatsu, Kagawa 761-0395, Japan.

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http://dx.doi.org/10.1016/j.febslet.2004.06.048DOI Listing
July 2004

Antisense inhibition of Bcr-Abl/c-Abl synthesis promotes telomerase activity and upregulates tankyrase in human leukemia cells.

FEBS Lett 2004 Apr;564(1-2):73-84

Single-Molecule Bioanalysis Laboratory, National Institute for Advanced Industrial Science and Technology, AIST-Shikoku, 2217-14 Hayashi-cho, Takamatsu, Kagawa 761-0395, Japan.

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http://doi.wiley.com/10.1016/S0014-5793%2804%2900318-7
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http://dx.doi.org/10.1016/S0014-5793(04)00318-7DOI Listing
April 2004

Phenothiazines suppress proliferation and induce apoptosis in cultured leukemic cells without any influence on the viability of normal lymphocytes. Phenothiazines and leukemia.

Cancer Chemother Pharmacol 2004 Mar 9;53(3):267-75. Epub 2003 Dec 9.

National Institute for Advanced Industrial Science and Technology, AIST-Shikoku, 2217-14 Hayashi-cho, 761-0395 Takamatsu, Kagawa, Japan.

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http://link.springer.com/10.1007/s00280-003-0738-1
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http://dx.doi.org/10.1007/s00280-003-0738-1DOI Listing
March 2004

Cross-talk between Bcr-Abl tyrosine kinase, protein kinase C and telomerase-a potential reason for resistance to Glivec in chronic myelogenous leukaemia.

Biochem Pharmacol 2003 Nov;66(10):1879-84

National Institute of Advanced Industrial Science and Technology, AIST-Shikoku, 2217-14 Hayashi-cho, 761-0395 Takamatsu, Japan.

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http://dx.doi.org/10.1016/j.bcp.2003.06.001DOI Listing
November 2003

Unique dual fluorescence of sterically congested hexaalkyl benzenehexacarboxylates: mechanism and application to viscosity probing.

J Am Chem Soc 2002 Jun;124(24):6942-9

ICORP Entropy Control Project (JST), Venture Business Laboratory, and Department of Molecular Chemistry, Osaka University, 2-1 Yamada-oka, Suita 565-0871, Japan.

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http://dx.doi.org/10.1021/ja016858lDOI Listing
June 2002