Mitesh J Borad

Mitesh J Borad

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Mitesh J Borad

Publications by authors named "Mitesh J Borad"

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Advances in the treatment of biliary tract cancers.

Curr Opin Gastroenterol 2020 Mar;36(2):85-89

Mayo Clinic Cancer Center, Division of Hematology/Oncology, Mayo Clinic, Phoenix, Arizona, USA.

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http://dx.doi.org/10.1097/MOG.0000000000000606DOI Listing
March 2020

Second-line therapies in advanced biliary tract cancers.

Lancet Oncol 2020 Jan;21(1):e29-e41

Department of Oncology, Mayo Clinic, Rochester, MN, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(19)30733-8DOI Listing
January 2020

Somatic genetic aberrations in gallbladder cancer: comparison between Chinese and US patients.

Hepatobiliary Surg Nutr 2019 Dec;8(6):604-614

National Cancer Center/National Clinical Research Center for Cancer/Department of Pancreatic and Gastric Surgery, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College/National Cancer Center/National Clinical Research Center for Cancer/Department of Hepatobiliary and Pancreatic Surgery, Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen 518116, China.

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http://dx.doi.org/10.21037/hbsn.2019.04.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6943012PMC
December 2019

MetaMarker: a pipeline for de novo discovery of novel metagenomic biomarkers.

Bioinformatics 2019 Oct;35(19):3812-3814

Department of Health Sciences Research and Center for Individualized Medicine, Mayo Clinic, Scottsdale, AZ, USA.

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http://dx.doi.org/10.1093/bioinformatics/btz123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761932PMC
October 2019

Neoadjuvant vs. adjuvant chemotherapy for cholangiocarcinoma: A propensity score matched analysis.

Eur J Surg Oncol 2019 Aug 21;45(8):1432-1438. Epub 2019 Mar 21.

Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejso.2019.03.023DOI Listing
August 2019

Feasibility of circulating tumor DNA testing in hepatocellular carcinoma.

J Gastrointest Oncol 2019 Aug;10(4):745-750

Division of Hematology/Oncology, Mayo Clinic Cancer Center, Mayo Clinic, Scottsdale, AZ, USA.

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http://dx.doi.org/10.21037/jgo.2019.02.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657310PMC
August 2019

Prognostic subclass of intrahepatic cholangiocarcinoma by integrative molecular-clinical analysis and potential targeted approach.

Hepatol Int 2019 Jul 18;13(4):490-500. Epub 2019 Jun 18.

Department of Surgery, Dongsan Medical Center, School of Medicine, Keimyung University, 56 Dalseong-ro, Jung-gu, Daegu, 700-712, Republic of Korea.

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http://dx.doi.org/10.1007/s12072-019-09954-3DOI Listing
July 2019

Preclinical In Vitro and In Vivo Evidence of an Antitumor Effect of CX-4945, a Casein Kinase II Inhibitor, in Cholangiocarcinoma.

Transl Oncol 2019 Jan 11;12(1):143-153. Epub 2018 Oct 11.

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2018.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6187100PMC
January 2019

Emerging role of precision medicine in biliary tract cancers.

NPJ Precis Oncol 2018 3;2:21. Epub 2018 Oct 3.

1Division of Hematology/Oncology, Department of Medicine, Mayo Clinic, Scottsdale, AZ USA.

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http://www.nature.com/articles/s41698-018-0064-z
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http://dx.doi.org/10.1038/s41698-018-0064-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170410PMC
October 2018

Novel immunotherapy strategies for hepatobiliary cancers.

Immunotherapy 2018 09;10(12):1077-1091

Department of Medicine, Division of Hematology & Oncology, Mayo Clinic, Scottsdale, AZ 85259, USA.

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http://dx.doi.org/10.2217/imt-2018-0024DOI Listing
September 2018

Exploring the role of oncolytic viruses in hepatobiliary cancers.

Immunotherapy 2018 08 14;10(11):971-986. Epub 2018 Jun 14.

Assistant Professor of Medicine, Department of Medicine, Hematology & Oncology division, University of Arizona, Tucson, AZ 85721, USA.

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https://www.futuremedicine.com/doi/10.2217/imt-2018-0048
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http://dx.doi.org/10.2217/imt-2018-0048DOI Listing
August 2018

Surveillance for hepatobiliary cancers in patients with primary sclerosing cholangitis.

Hepatology 2018 06 19;67(6):2338-2351. Epub 2018 Apr 19.

Division of Gastroenterology and Hepatology, Mayo Clinic, Phoenix, AZ.

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http://dx.doi.org/10.1002/hep.29730DOI Listing
June 2018

Novel targeted therapy strategies for biliary tract cancers and hepatocellular carcinoma.

Future Oncol 2018 Mar 20;14(6):553-566. Epub 2018 Feb 20.

Division of Hematology Oncology, Department of Medicine, Mayo Clinic, Scottsdale, AZ 85259, USA.

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http://dx.doi.org/10.2217/fon-2017-0451DOI Listing
March 2018

Oncolytic Adenoviruses in Gastrointestinal Cancers.

Biomedicines 2018 Mar 11;6(1). Epub 2018 Mar 11.

Department of Medicine, Division of Hematology Oncology, Mayo Clinic Arizona, 13400 E Shea Blvd, Scottsdale, AZ 85205, USA.

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http://www.mdpi.com/2227-9059/6/1/33
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http://dx.doi.org/10.3390/biomedicines6010033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874690PMC
March 2018

Oncolytic virotherapy in upper gastrointestinal tract cancers.

Oncolytic Virother 2017 23;7:13-24. Epub 2018 Mar 23.

Division of Hematology/Oncology, Department of Medicine, Mayo Clinic, Scottsdale, AZ.

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http://dx.doi.org/10.2147/OV.S161397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870634PMC
March 2018

Phase II Study of BGJ398 in Patients With FGFR-Altered Advanced Cholangiocarcinoma.

J Clin Oncol 2018 01 28;36(3):276-282. Epub 2017 Nov 28.

Milind Javle and Rachna T. Shroff, The University of Texas MD Anderson Cancer Center, Houston, TX; Maeve Lowery and Ghassan K. Abou-Alfa, Memorial Sloan Kettering Cancer Center, and Weill Cornell Medical College, New York, NY; Karl Heinz Weiss and Christoph Springfeld, Universitäts Klinikum Heidelberg, Heidelberg, Germany; Mitesh J. Borad, Ramesh K. Ramanathan, and Tanios Bekaii-Saab, Mayo Clinic, Phoenix, AZ; Lipika Goyal and Andrew X. Zhu, Massachusetts General Hospital Cancer Center, Boston, MA; Saeed Sadeghi and Richard S. Finn, David Geffen School of Medicine at UCLA; Anthony El-Khoueiry, USC Norris Comprehensive Cancer Center, Keck School of Medicine, Los Angeles; Robin Kate Kelley, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA; Teresa Macarulla, Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Barcelona, Spain; Ivan Borbath, Cliniques Universitaires Saint-Luc, Brussels; Eric Van Cutsem, University Hospitals Gasthuisberg and KU Leuven, Leuven, Belgium; Su Pin Choo, National Cancer Centre of Singapore, Singapore; Do-Youn Oh, Seoul National University, Seoul, South Korea; Philip A. Philip, Karmanos Cancer Institute, Detroit, MI; Li-Tzong Chen, National Institute of Cancer Research and National Cheng Kung University Hospital, Tainan; Kun-Huei Yeh, National Taiwan University Hospital Cancer Center, and Cancer Research Center, National Taiwan University College of Medicine, Taipei, Taiwan; Thanyanan Reungwetwattana, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; Kristen Ciombor, The Ohio State University Wexner Medical Center, Columbus, OH; and Anuradha Patel, Suman Sen, Dale Porter, and Randi Isaacs, Novartis Pharmaceuticals Corporation, East Hanover, NJ.

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http://dx.doi.org/10.1200/JCO.2017.75.5009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075847PMC
January 2018

Second-line treatment in patients with pancreatic ductal adenocarcinoma: A meta-analysis.

Cancer 2017 Dec 17;123(23):4680-4686. Epub 2017 Aug 17.

Mayo Clinic Cancer Center, Mayo Clinic, Phoenix, Arizona.

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http://dx.doi.org/10.1002/cncr.30927DOI Listing
December 2017

Oncolytic virus delivery: from nano-pharmacodynamics to enhanced oncolytic effect.

Oncolytic Virother 2017 8;6:39-49. Epub 2017 Nov 8.

Division of Hematology Oncology, Department of Medicine, Mayo Clinic, Scottsdale.

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http://dx.doi.org/10.2147/OV.S145262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687448PMC
November 2017

Twenty-First Century Precision Medicine in Oncology: Genomic Profiling in Patients With Cancer.

Mayo Clin Proc 2017 10;92(10):1583-1591

Yale Cancer Center, Yale School of Medicine, New Haven, CT.

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http://dx.doi.org/10.1016/j.mayocp.2017.08.002DOI Listing
October 2017

Using Naïve Bayesian Analysis to Determine Imaging Characteristics of KRAS Mutations in Metastatic Colon Cancer.

Diagnostics (Basel) 2017 Sep 2;7(3). Epub 2017 Sep 2.

Department of Radiology, Division of Vascular & Interventional Radiology, Mayo Clinic, Phoenix, AZ 85054, USA.

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http://dx.doi.org/10.3390/diagnostics7030050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617950PMC
September 2017

Molecular Modeling and Functional Analysis of Exome Sequencing-Derived Variants of Unknown Significance Identify a Novel, Constitutively Active FGFR2 Mutant in Cholangiocarcinoma.

JCO Precis Oncol 2017 1;2017. Epub 2017 Aug 1.

David L. Marks, Tara L. Hogenson, Anne M. Vrabel, Ashley N. Sigafoos, Ezequiel J. Tolosa, Ryan M. Carr, Stephanie L. Safgren, Elisa Enriquez Hesles, Luciana L. Almada, Paola A. Romecin-Duran, Eriko Iguchi, Aryan Ala'Aldeen, Jean-Pierre A. Kocher, Gavin R. Oliver, Naresh Prodduturi, David W. Mead, Asif Hossain, Norine E. Huneke, Colleen M. Tagtow, Sikander Ailawadhi, Stephen M. Ansell, Michaela S. Banck, Asher A. Chanan-Khan, Ronald S. Go, Thorvardur R. Halfdanarson, Richard W. Joseph, Prashant Kapoor, Aaron S. Mansfield, Amulya A. Nageswara Rao, Grzegorz S. Nowakowski, Animesh Pardanani, Sameer A. Parikh, John C. Cheville, Andrew L. Feldman, Ramesh K. Ramanathan, Steven I. Robinson, Heidi D. Finnes, Jennifer B. McCormick, Robert R. McWilliams, Aminah Jatoi, Mrinal M. Patnaik, Eric D. Wieben, Tammy M. McAllister, Kandelaria M. Rumilla, Sarah E. Kerr, Konstantinos N. Lazaridis, Gianrico Farrugia, Karl J. Clark, Eric W. Klee, and Martin E. Fernandez-Zapico, Mayo Clinic, Rochester; Ernesto Resnik, Bio-Techne, Minneapolis, MN; Sikander Ailawadhi, Asher A. Chanan-Khan, and Richard W. Joseph, Mayo Clinic, Jacksonville, FL; Jan B. Egan, Alan H. Bryce, Estrella M. Carballido, KellyK. Curtis, Chelsea D. Gawryletz, Thai H. Ho,Nathalie Meurice, Ramesh K. Ramanathan, Raoul Tibes, Alvin C. Silva, A. Keith Stewart, and Mitesh J. Borad, Mayo Clinic, Phoenix, AZ; and Eileen J. Kennedy, University of Georgia, Athens, GA.

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http://dx.doi.org/10.1200/PO.17.00018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369924PMC
August 2017

Hypoxia-Activated Alkylating Agents in BRCA1-Mutant Ovarian Serous Carcinoma.

Cureus 2017 Jul 26;9(7):e1517. Epub 2017 Jul 26.

Hematology Oncology, Mayo Clinic, Scottsdale, AZ.

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http://dx.doi.org/10.7759/cureus.1517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5613928PMC
July 2017

Hypoxia-activated prodrugs in the treatment of advanced pancreatic adenocarcinoma.

Anticancer Drugs 2017 02;28(2):127-132

aVirginia G Piper Cancer Center Clinical Trials, HonorHealth Research Institute bDepartment of Internal Medicine, Division of Hematology-Oncology, Mayo Clinic Cancer Center, Scottsdale cClinical Translational Research Division, Translational Genomics Research Institute (TGen), Phoenix dDepartment of Internal Medicine, Division of Hematology Oncology, University of Arizona Cancer Center eDepartment of Internal Medicine, University of Arizona, Tucson, Arizona fDepartment of Molecular Medicine, Centre for Individualized Medicine, Rochester, Minnesota, USA gDepartment of Medicine, Dow University of Health Sciences, Karachi, Pakistan.

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http://dx.doi.org/10.1097/CAD.0000000000000437DOI Listing
February 2017

Oncolytic virotherapy including Rigvir and standard therapies in malignant melanoma.

Oncolytic Virother 2017 9;6:11-18. Epub 2017 Feb 9.

Division of Hematology-Oncology, Mayo Clinic Cancer Center, Scottsdale, AZ; Department of Molecular Medicine, Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.2147/OV.S100072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308590PMC
February 2017

Immunotherapy in pancreatic cancer treatment: a new frontier.

Therap Adv Gastroenterol 2017 Jan 17;10(1):168-194. Epub 2016 Oct 17.

Division of Hematology/Oncology, Mayo Clinic Arizona, 5777 E. Mayo Boulevard, Phoenix, AZ 85054, USA.

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http://dx.doi.org/10.1177/1756283X16667909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330603PMC
January 2017

The rise of the FGFR inhibitor in advanced biliary cancer: the next cover of time magazine?

J Gastrointest Oncol 2016 Oct;7(5):789-796

Division of Hematology and Oncology, Mayo Clinic, Scottsdale, Arizona, USA.

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http://jgo.amegroups.com/article/view/9610/html
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http://dx.doi.org/10.21037/jgo.2016.08.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056253PMC
October 2016

Oncolytic viruses: perspectives on clinical development.

Curr Opin Virol 2015 Aug 16;13:55-60. Epub 2015 May 16.

SillaJen Biotherapeutics, 450 Sansome Street, Suite 650, San Francisco, CA 94111, United States.

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http://dx.doi.org/10.1016/j.coviro.2015.03.020DOI Listing
August 2015

Randomized Phase II Trial of Gemcitabine Plus TH-302 Versus Gemcitabine in Patients With Advanced Pancreatic Cancer.

J Clin Oncol 2015 May 15;33(13):1475-81. Epub 2014 Dec 15.

Mitesh J. Borad, Mayo Clinic, Scottsdale; Tomislav Dragovich, Arizona Cancer Center, Tucson, AZ; Shantan G. Reddy, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA; Nathan Bahary, University of Pittsburgh Medical Center, Pittsburgh, PA; Hope E. Uronis, Duke University Medical Center, Durham, NC; Darren Sigal, Scripps Clinic, La Jolla; Peter J. Rosen, Disney Family Cancer Center, Burbank; Clarence Eng and Stew Kroll, Threshold Pharmaceuticals, South San Francisco, CA; Allen L. Cohn, Rocky Mountain Cancer Center, Denver, CO; William R. Schelman, University of Wisconsin Carbone Cancer Center, Madison, WI; Joe Stephenson Jr, Institute for Translational Oncology Research, Greenville, SC; E. Gabriela Chiorean, Indiana University Simon Cancer Center, Indianapolis, IN; Brian Ulrich, Texas Oncology, Wichita Falls, TX; Salvatore A. Del Prete, Hematology Oncology PC, Stamford, CT; Mark Rarick, Kaiser Permanente Northwest Region Oncology Hematology, Portland, OR; and David P. Ryan, Massachusetts General Hospital Cancer Center, Boston, MA.

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http://dx.doi.org/10.1200/JCO.2014.55.7504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881365PMC
May 2015

Fibroblast growth factor receptor 2 fusions as a target for treating cholangiocarcinoma.

Curr Opin Gastroenterol 2015 May;31(3):264-8

aDivision of Hematology/Oncology, Mayo Clinic, Scottsdale, Arizona bDepartment of Molecular Medicine cDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1097/MOG.0000000000000171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750878PMC
May 2015

Cholangiocarcinoma: molecular pathways and therapeutic opportunities.

Semin Liver Dis 2014 Nov 4;34(4):456-64. Epub 2014 Nov 4.

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1055/s-0034-1394144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294543PMC
November 2014

Phase I trial of everolimus, gemcitabine and cisplatin in patients with solid tumors.

Invest New Drugs 2014 Aug 18;32(4):710-6. Epub 2014 Apr 18.

Mayo Clinic Cancer Center, 200 First Street SW, Rochester, MN, 55905, USA,

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http://dx.doi.org/10.1007/s10637-014-0096-3DOI Listing
August 2014

Immunotherapeutic and oncolytic viral therapeutic strategies in pancreatic cancer.

Future Oncol 2014 May;10(7):1255-75

Mayo Clinic Arizona Division of Hematology & Medical Oncology, 13400 E Shea Boulevard, Scottsdale, AZ 85259, USA.

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https://www.futuremedicine.com/doi/10.2217/fon.13.277
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http://dx.doi.org/10.2217/fon.13.277DOI Listing
May 2014

Simultaneous characterization of somatic events and HPV-18 integration in a metastatic cervical carcinoma patient using DNA and RNA sequencing.

Int J Gynecol Cancer 2014 Feb;24(2):329-38

*Translational Genomics Research Institute; †Comprehensive Cancer Care, St Joseph's Hospital and Medical Center, Phoenix; ‡Mayo Clinic, Scottsdale; §Department of Obstetrics and Gynecology, St Joseph's Hospital and Medical Center, and ∥Division of Gynecologic Oncology, Creighton University School of Medicine, St Joseph's Hospital and Medical Center, University of Arizona Cancer Center, Phoenix, AZ.

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http://dx.doi.org/10.1097/IGC.0000000000000049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921261PMC
February 2014

Advances in systemic therapy for advanced pancreatobiliary malignancies.

F1000Res 2013 8;2:105. Epub 2013 Apr 8.

Division of Hematology and Medical Oncology, Mayo Clinic Arizona, Scottsdale, AZ, USA.

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http://dx.doi.org/10.12688/f1000research.2-105.v1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752657PMC
April 2013

Advances in systemic therapy for advanced pancreatobiliary malignancies.

F1000Res 2013 Apr 8;2:105. Epub 2013 Apr 8.

Division of Hematology and Medical Oncology, Mayo Clinic Arizona, Scottsdale, AZ, USA.

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http://dx.doi.org/10.12688/f1000research.2-105.v1DOI Listing
April 2013

Reduced acute bowel toxicity in patients treated with intensity-modulated radiotherapy for rectal cancer.

Int J Radiat Oncol Biol Phys 2012 Apr 7;82(5):1981-7. Epub 2011 Apr 7.

Department of Radiation Oncology, Mayo Clinic, Scottsdale, AZ, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2011.01.051DOI Listing
April 2012

Patient willingness to undergo pharmacodynamic and pharmacokinetic tests in early phase oncology trials.

Cancer 2011 Jul 18;117(14):3276-83. Epub 2011 Jan 18.

Translational Genomics Research Institute and Virginia G. Piper Cancer Center, Phoenix/Scottsdale, Arizona, USA.

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http://dx.doi.org/10.1002/cncr.25885DOI Listing
July 2011

Isolated supraclavicular lymph node metastasis in pancreatic adenocarcinoma: a report of three cases and review of the literature.

JOP 2010 Nov 9;11(6):604-9. Epub 2010 Nov 9.

Department of Hematology/Oncology, Mayo Clinic Arizona, Scottsdale, AZ 85259, USA.

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November 2010

Marantic Endocarditis Associated with Pancreatic Cancer: A Case Series.

Case Rep Gastroenterol 2009 Apr 15;3(1):67-71. Epub 2009 Apr 15.

Scottsdale Clinical Research Institute, TGen Clinical Research Services, Ariz., USA.

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http://dx.doi.org/10.1159/000207195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895179PMC
April 2009

Skeletal metastases in pancreatic cancer: a retrospective study and review of the literature.

Yale J Biol Med 2009 Mar;82(1):1-6

Translational Genomics Research Institute, Scottsdale Clinical Research Institute, AZ, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660584PMC
March 2009