Minoru Takata

Minoru Takata

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Minoru Takata

Publications by authors named "Minoru Takata"

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Pilot evaluation of a HER2 testing in non-small-cell lung cancer.

J Clin Pathol 2020 Jun 3;73(6):353-357. Epub 2019 Dec 3.

Department of Respiratory Medicine, Okayama University Hospital, Okayama, Japan.

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http://dx.doi.org/10.1136/jclinpath-2019-206204DOI Listing
June 2020

Significance of 5--Cysteinyldopa as a Marker for Melanoma.

Int J Mol Sci 2020 Jan 9;21(2). Epub 2020 Jan 9.

Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.3390/ijms21020432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013534PMC
January 2020

[Genetic analysis of Japanese patients with Fanconi anemia: novel findings].

Rinsho Ketsueki 2019 ;60(6):691-701

Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Graduate School of Biostudies, Kyoto University.

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http://dx.doi.org/10.11406/rinketsu.60.691DOI Listing
August 2019

Regulation of R-loops and genome instability in Fanconi anemia.

J Biochem 2019 Jun;165(6):465-470

Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Graduate School of Biostudies, Radiation Biology Center, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto, Japan.

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https://academic.oup.com/jb/advance-article/doi/10.1093/jb/m
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http://dx.doi.org/10.1093/jb/mvz019DOI Listing
June 2019

FANCD2 protects genome stability by recruiting RNA processing enzymes to resolve R-loops during mild replication stress.

FEBS J 2019 01 27;286(1):139-150. Epub 2018 Nov 27.

Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Graduate School of Biostudies, Kyoto University, Japan.

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http://doi.wiley.com/10.1111/febs.14700
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http://dx.doi.org/10.1111/febs.14700DOI Listing
January 2019

Warsaw breakage syndrome DDX11 helicase acts jointly with RAD17 in the repair of bulky lesions and replication through abasic sites.

Proc Natl Acad Sci U S A 2018 08 30;115(33):8412-8417. Epub 2018 Jul 30.

DNA Repair lab, IFOM, Fondazione Italiana per la Ricerca sul Cancro Institute of Molecular Oncology, 20139 Milan, Italy;

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http://dx.doi.org/10.1073/pnas.1803110115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099846PMC
August 2018

Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2.

Mol Cell 2018 07 21;71(1):25-41.e6. Epub 2018 Jun 21.

Genome Stability and Human Disease Laboratory, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham B15 2TT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039718PMC
July 2018

Activation of the FA pathway mediated by phosphorylation and ubiquitination.

Mutat Res 2017 10 5;803-805:89-95. Epub 2017 May 5.

Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Kyoto University, Kyoto, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.mrfmmm.2017.05.003DOI Listing
October 2017

Editorial.

Authors:
Minoru Takata

Mutat Res 2017 10 10;803-805:42. Epub 2017 Jun 10.

Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Kyoto University, Kyoto, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00275107173010
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http://dx.doi.org/10.1016/j.mrfmmm.2017.06.001DOI Listing
October 2017

Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia.

J Clin Invest 2017 Aug 10;127(8):3013-3027. Epub 2017 Jul 10.

Department of Human Genetics, Biozentrum, University of Wurzburg, Wurzburg, Germany.

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http://dx.doi.org/10.1172/JCI92069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531404PMC
August 2017

WITHDRAWN: Mut Res special section "Protein modifications in DNA repair and cancer".

Authors:
Minoru Takata

Mutat Res 2017 Jun 15. Epub 2017 Jun 15.

Kyoto University, Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Kyoto, 606-8501, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00275107173011
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http://dx.doi.org/10.1016/j.mrfmmm.2017.06.003DOI Listing
June 2017

Usefulness of serum 5-S-cysteinyl-dopa as a biomarker for predicting prognosis and detecting relapse in patients with advanced stage malignant melanoma.

J Dermatol 2017 Apr 27;44(4):449-454. Epub 2016 Oct 27.

Department of Dermatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

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http://dx.doi.org/10.1111/1346-8138.13651DOI Listing
April 2017

Trastuzumab Emtansine in HER2+ Recurrent Metastatic Non-Small-Cell Lung Cancer: Study Protocol.

Clin Lung Cancer 2017 01 9;18(1):92-95. Epub 2016 Jul 9.

Department of Respiratory Medicine, Okayama University Hospital, Okayama, Japan.

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http://dx.doi.org/10.1016/j.cllc.2016.06.014DOI Listing
January 2017

Comparative study on driver mutations in primary and metastatic melanomas at a single Japanese institute: A clue for intra- and inter-tumor heterogeneity.

J Dermatol Sci 2017 Jan 13;85(1):51-57. Epub 2016 Oct 13.

Department of Dermatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan; Melanoma Center, Okayama University Hospital, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2016.10.006DOI Listing
January 2017

FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5'-DNA end.

Nucleic Acids Res 2016 12 30;44(22):10758-10771. Epub 2016 Sep 30.

Laboratory of Structural Biology, Graduate School of Advanced Science & Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan

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http://dx.doi.org/10.1093/nar/gkw876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159555PMC
December 2016

The phenotype and clinical course of Japanese Fanconi Anaemia infants is influenced by patient, but not maternal ALDH2 genotype.

Br J Haematol 2016 Nov 5;175(3):457-461. Epub 2016 Jul 5.

Laboratory of DNA Damage Signalling, Department of Late Effects Studies, Radiation Biology Centre, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1111/bjh.14243DOI Listing
November 2016

Defects in homologous recombination repair behind the human diseases: FA and HBOC.

Endocr Relat Cancer 2016 10 22;23(10):T19-37. Epub 2016 Aug 22.

Laboratory of DNA Damage SignalingDepartment of Late Effects Studies, Radiation Biology Center, Kyoto University, Yoshidakonoecho, Sakyo-ku, Kyoto, Japan

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http://dx.doi.org/10.1530/ERC-16-0221DOI Listing
October 2016

Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells.

Oncotarget 2016 Sep;7(37):59795-59808

Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516, USA.

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http://dx.doi.org/10.18632/oncotarget.10928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312349PMC
September 2016

Effect of Vandetanib on Lung Tumorigenesis in Transgenic Mice Carrying an Activating Egfr Gene Mutation.

Acta Med Okayama 2016 Aug;70(4):243-53

Department of Haematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558,

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http://dx.doi.org/10.18926/AMO/54499DOI Listing
August 2016

Defective FANCI binding by a fanconi anemia-related FANCD2 mutant.

PLoS One 2014 9;9(12):e114752. Epub 2014 Dec 9.

Laboratory of Structural Biology, Graduate School of Advanced Science & Engineering, Waseda University, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114752PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260917PMC
December 2015

Conserved overlapping gene arrangement, restricted expression, and biochemical activities of DNA polymerase ν (POLN).

J Biol Chem 2015 Oct 12;290(40):24278-93. Epub 2015 Aug 12.

From the Department of Epigenetics and Molecular Carcinogenesis, University of Texas M.D. Anderson Cancer Center, Smithville, Texas 78957, the University of Texas Graduate School of Biomedical Sciences at Houston, Houston, Texas 77030.

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http://dx.doi.org/10.1074/jbc.M115.677419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591814PMC
October 2015

Third Report on Chicken Genes and Chromosomes 2015.

Authors:
Michael Schmid Jacqueline Smith David W Burt Bronwen L Aken Parker B Antin Alan L Archibald Chris Ashwell Perry J Blackshear Clarissa Boschiero C Titus Brown Shane C Burgess Hans H Cheng William Chow Derrick J Coble Amanda Cooksey Richard P M A Crooijmans Joana Damas Richard V N Davis Dirk-Jan de Koning Mary E Delany Thomas Derrien Takele T Desta Ian C Dunn Matthew Dunn Hans Ellegren Lél Eöry Ionas Erb Marta Farré Mario Fasold Damarius Fleming Paul Flicek Katie E Fowler Laure Frésard David P Froman Valerie Garceau Paul P Gardner Almas A Gheyas Darren K Griffin Martien A M Groenen Thomas Haaf Olivier Hanotte Alan Hart Julien Häsler S Blair Hedges Jana Hertel Kerstin Howe Allen Hubbard David A Hume Pete Kaiser Darek Kedra Stephen J Kemp Christophe Klopp Kalmia E Kniel Richard Kuo Sandrine Lagarrigue Susan J Lamont Denis M Larkin Raman A Lawal Sarah M Markland Fiona McCarthy Heather A McCormack Marla C McPherson Akira Motegi Stefan A Muljo Andrea Münsterberg Rishi Nag Indrajit Nanda Michael Neuberger Anne Nitsche Cedric Notredame Harry Noyes Rebecca O'Connor Elizabeth A O'Hare Andrew J Oler Sheila C Ommeh Helio Pais Michael Persia Frédérique Pitel Likit Preeyanon Pablo Prieto Barja Elizabeth M Pritchett Douglas D Rhoads Charmaine M Robinson Michael N Romanov Max Rothschild Pierre-François Roux Carl J Schmidt Alisa-Sophia Schneider Matthew G Schwartz Steve M Searle Michael A Skinner Craig A Smith Peter F Stadler Tammy E Steeves Claus Steinlein Liang Sun Minoru Takata Igor Ulitsky Qing Wang Ying Wang Wesley C Warren Jonathan M D Wood David Wragg Huaijun Zhou

Cytogenet Genome Res 2015 14;145(2):78-179. Epub 2015 Jul 14.

Department of Human Genetics, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1159/000430927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120589PMC
October 2015

Human FAN1 promotes strand incision in 5'-flapped DNA complexed with RPA.

J Biochem 2015 Sep 27;158(3):263-70. Epub 2015 Apr 27.

Laboratory of Structural Biology, Graduate School of Advanced Science & Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan and

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http://dx.doi.org/10.1093/jb/mvv043DOI Listing
September 2015

Expression and purification of human FANCI and FANCD2 using Escherichia coli cells.

Protein Expr Purif 2014 Nov 26;103:8-15. Epub 2014 Aug 26.

Laboratory of Structural Biology, Graduate School of Advanced Science & Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.pep.2014.08.012DOI Listing
November 2014

Multiple genetic manipulations of DT40 cell line.

Methods Mol Biol 2014 ;1114:25-35

Department of Radiation Genetics, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, Japan.

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http://link.springer.com/10.1007/978-1-62703-761-7_3
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http://dx.doi.org/10.1007/978-1-62703-761-7_3DOI Listing
October 2014

The Trp53-Trp53inp1-Tnfrsf10b pathway regulates the radiation response of mouse spermatogonial stem cells.

Stem Cell Reports 2014 Oct 18;3(4):676-89. Epub 2014 Sep 18.

Department of Molecular Genetics, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan; Japan Science and Technology Agency, CREST, Kyoto 606-8501, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2014.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223695PMC
October 2014

Modularized functions of the Fanconi anemia core complex.

Cell Rep 2014 Jun 5;7(6):1849-57. Epub 2014 Jun 5.

Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://www.cell.com/cell-reports/pdf/S2211-1247(14)00331-3.p
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http://linkinghub.elsevier.com/retrieve/pii/S221112471400331
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http://dx.doi.org/10.1016/j.celrep.2014.04.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157997PMC
June 2014

Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents.

Biochim Biophys Acta 2014 May 10;1843(5):1002-12. Epub 2014 Jan 10.

Molecular Cell Biology Laboratory, Research Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Musashino University, 1-1-20 Shinmachi, Nishitokyo-shi, Tokyo 202-8585, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2014.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5525539PMC
May 2014

FANCD2 binds CtIP and regulates DNA-end resection during DNA interstrand crosslink repair.

Cell Rep 2014 May 1;7(4):1039-47. Epub 2014 May 1.

Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Kyoto University, Kyoto 606-8501, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247140029
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http://dx.doi.org/10.1016/j.celrep.2014.04.005DOI Listing
May 2014

[Fanconi anemia and the molecular mechanism of the repair of DNA crosslinks].

Rinsho Ketsueki 2013 Oct;54(10):1625-32

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October 2013

A novel interplay between the Fanconi anemia core complex and ATR-ATRIP kinase during DNA cross-link repair.

Nucleic Acids Res 2013 Aug 30;41(14):6930-41. Epub 2013 May 30.

Department of Late Effects Studies, Laboratory of DNA Damage Signaling, Kyoto University, Kyoto 606-8501, Japan, Japan Society for the Promotion of Science (JSPS), Tokyo 102-0083, Japan.

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http://dx.doi.org/10.1093/nar/gkt467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737553PMC
August 2013

NBS1 directly activates ATR independently of MRE11 and TOPBP1.

Genes Cells 2013 Mar 1;18(3):238-46. Epub 2013 Feb 1.

Department of Molecular Pathology, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa, 920-1192, Japan.

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http://doi.wiley.com/10.1111/gtc.12031
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http://dx.doi.org/10.1111/gtc.12031DOI Listing
March 2013

Synergistic effect of olaparib with combination of cisplatin on PTEN-deficient lung cancer cells.

Mol Cancer Res 2013 Feb 13;11(2):140-8. Epub 2012 Dec 13.

Department of Hematology, Oncology, and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical ciences, Okayama, Japan.

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http://mcr.aacrjournals.org/cgi/doi/10.1158/1541-7786.MCR-12
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http://dx.doi.org/10.1158/1541-7786.MCR-12-0401DOI Listing
February 2013

Establishment of the DNA repair-defective mutants in DT40 cells.

Methods Mol Biol 2012 ;920:39-49

Laboratory of DNA Damage Signaling, Department of Late Effect Studies, Radiation Biology Center, Kyoto University, Kyoto, Japan.

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http://link.springer.com/10.1007/978-1-61779-998-3_4
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http://dx.doi.org/10.1007/978-1-61779-998-3_4DOI Listing
January 2013

Mcm8 and Mcm9 form a complex that functions in homologous recombination repair induced by DNA interstrand crosslinks.

Mol Cell 2012 Aug 5;47(4):511-22. Epub 2012 Jul 5.

Center for Frontier Research, National Institute of Genetics, Research Organization of Information and Systems, Yata 1111, Mishima, Shizuoka 411-8540, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S109727651200493
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http://dx.doi.org/10.1016/j.molcel.2012.05.047DOI Listing
August 2012

Cutaneous angiosarcoma of the leg showing radiation sensitivity.

Australas J Dermatol 2012 Aug 29;53(3):e51-3. Epub 2011 Mar 29.

Department of Dermatology, Shinshu University School of Medicine, Asahi, Matsumoto, Japan.

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http://dx.doi.org/10.1111/j.1440-0960.2011.00746.xDOI Listing
August 2012

DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI.

Nucleic Acids Res 2012 May 28;40(10):4553-61. Epub 2012 Jan 28.

Laboratory of Structural Biology, Graduate School of Advanced Science and Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gks053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378891PMC
May 2012

ATR-ATRIP kinase complex triggers activation of the Fanconi anemia DNA repair pathway.

Cancer Res 2012 Mar 18;72(5):1149-56. Epub 2012 Jan 18.

Laboratory of DNA Damage Signaling, Department of Late Effects Studies, Radiation Biology Center, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-2904DOI Listing
March 2012

Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome.

Proc Natl Acad Sci U S A 2012 Mar 5;109(12):4437-42. Epub 2012 Mar 5.

Department of Biomolecular Chemistry, 420 Henry Mall, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA.

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http://dx.doi.org/10.1073/pnas.1117279109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3311393PMC
March 2012

Direct inhibition of TNF-α promoter activity by Fanconi anemia protein FANCD2.

PLoS One 2011 31;6(8):e23324. Epub 2011 Aug 31.

Laboratory of Molecular Biochemistry, School of Life Science, Tokyo University of Pharmacy and Life Science, Hachioji, Tokyo, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0023324PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166142PMC
December 2011

Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway.

Nat Struct Mol Biol 2011 Nov 13;18(12):1432-4. Epub 2011 Nov 13.

Medical Research Council Laboratory of Molecular Biology, Cambridge, UK.

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http://www.nature.com/articles/nsmb.2173
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http://dx.doi.org/10.1038/nsmb.2173DOI Listing
November 2011

Evaluation of homologous recombinational repair in chicken B lymphoma cell line, DT40.

Methods Mol Biol 2011 ;745:293-309

Department of Molecular Oncology, Kyushu University, Kyushu, Japan.

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http://dx.doi.org/10.1007/978-1-61779-129-1_17DOI Listing
September 2011

The role of SNM1 family nucleases in etoposide-induced apoptosis.

Biochem Biophys Res Commun 2011 Jul 12;410(3):568-73. Epub 2011 Jun 12.

Molecular Cell Biology Laboratory, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba 6-3, Aramaki, Sendai, Miyagi 980-8578, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2011.06.027DOI Listing
July 2011

USP1 deubiquitinase maintains phosphorylated CHK1 by limiting its DDB1-dependent degradation.

Hum Mol Genet 2011 Jun 9;20(11):2171-81. Epub 2011 Mar 9.

Genome Instability and Carcinogenesis UPR3081 CNRS, IGC, IMM, 31 chemin Joseph Aiguier, 13402 Marseille, France.

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http://dx.doi.org/10.1093/hmg/ddr103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090195PMC
June 2011

FancJ/Brip1 helicase protects against genomic losses and gains in vertebrate cells.

Genes Cells 2011 Jun;16(6):714-27

Laboratory of DNA Damage Signaling, Department of Late Effect Studies, Radiation Biology Center, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1111/j.1365-2443.2011.01523.xDOI Listing
June 2011

Fanconi anemia: a disorder defective in the DNA damage response.

Int J Hematol 2011 Apr 18;93(4):417-424. Epub 2011 Feb 18.

Laboratory of DNA damage signaling, Department of Late Effect Studies, Radiation Biology Center, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto, 606-8501, Japan.

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http://link.springer.com/10.1007/s12185-011-0777-z
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http://dx.doi.org/10.1007/s12185-011-0777-zDOI Listing
April 2011

Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway.

Proc Natl Acad Sci U S A 2011 Apr 4;108(16):6492-6. Epub 2011 Apr 4.

Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1073/pnas.1018487108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080998PMC
April 2011

Guest editorial: fanconi anemia and the DNA damage response.

Authors:
Minoru Takata

Int J Hematol 2011 Apr 12;93(4):415-416. Epub 2011 Apr 12.

Laboratory of DNA Damage Signaling, Department of Late Effect Studies, Radiation Biology Center, Kyoto University, Kyoto, Japan.

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http://link.springer.com/10.1007/s12185-011-0832-9
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http://dx.doi.org/10.1007/s12185-011-0832-9DOI Listing
April 2011

BM-ca is a newly defined type I/II anti-CD20 monoclonal antibody with unique biological properties.

Int J Oncol 2011 Feb 6;38(2):335-44. Epub 2010 Dec 6.

Late Effects Studies, Radiation Biology Center, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.3892/ijo.2010.864DOI Listing
February 2011

THAP5 is a DNA-binding transcriptional repressor that is regulated in melanoma cells during DNA damage-induced cell death.

Biochem Biophys Res Commun 2011 Jan 24;404(1):195-200. Epub 2010 Nov 24.

Biomolecular Science Center, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, FL 32826, USA.

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http://dx.doi.org/10.1016/j.bbrc.2010.11.092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034447PMC
January 2011

KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents.

Proc Natl Acad Sci U S A 2010 Dec 29;107(50):21553-7. Epub 2010 Nov 29.

Department of Radiation Genetics, Graduate School of Medicine, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1073/pnas.1011081107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003052PMC
December 2010

[Mechanisms of genomic instability in Fanconi anemia].

Rinsho Ketsueki 2010 Jul;51(7):546-52

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July 2010

The expression of human high molecular weight melanoma-associated antigen in acral lentiginous melanoma.

Biosci Trends 2010 Apr;4(2):86-9

Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.

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April 2010

Molecular pathogenesis of malignant melanoma: a different perspective from the studies of melanocytic nevus and acral melanoma.

Pigment Cell Melanoma Res 2010 Feb 25;23(1):64-71. Epub 2009 Sep 25.

Department of Dermatology, Shinshu University School of Medicine, Asahi, Matsumoto, Japan.

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http://doi.wiley.com/10.1111/j.1755-148X.2009.00645.x
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http://dx.doi.org/10.1111/j.1755-148X.2009.00645.xDOI Listing
February 2010

Sentinel lymph node biopsy in Japan.

Int J Clin Oncol 2009 Dec 5;14(6):490-6. Epub 2009 Dec 5.

Department of Dermatology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan.

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http://link.springer.com/10.1007/s10147-009-0941-0
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http://dx.doi.org/10.1007/s10147-009-0941-0DOI Listing
December 2009

Polyclonality of BRAF mutations in acquired melanocytic nevi.

J Natl Cancer Inst 2009 Oct 14;101(20):1423-7. Epub 2009 Sep 14.

Department of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan.

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http://dx.doi.org/10.1093/jnci/djp309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765260PMC
October 2009

Chemopreventive effects of gefitinib on nonsmoking-related lung tumorigenesis in activating epidermal growth factor receptor transgenic mice.

Cancer Res 2009 Sep 18;69(17):7088-95. Epub 2009 Aug 18.

Department of Hematology, Oncology, and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-4205DOI Listing
September 2009

The Fanconi anemia pathway: insights from somatic cell genetics using DT40 cell line.

Mutat Res 2009 Jul 17;668(1-2):92-102. Epub 2009 Jan 17.

Laboratory of DNA Damage Signaling, Department of Late Effect Studies, Radiation Biology Center, Kyoto University, Yoshida-konoe, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1016/j.mrfmmm.2008.12.012DOI Listing
July 2009

[Fanconi anemia and DNA-damage response network].

Tanpakushitsu Kakusan Koso 2009 Mar;54(4 Suppl):580-5

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March 2009

NADPH oxidase 4 contributes to transformation phenotype of melanoma cells by regulating G2-M cell cycle progression.

Cancer Res 2009 Mar 10;69(6):2647-54. Epub 2009 Mar 10.

Department of Dermatology, Shinshu University Graduate School of Medicine, Matsumoto, Nagano, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-3745DOI Listing
March 2009

Pathological activation of KIT in metastatic tumors of acral and mucosal melanomas.

Int J Cancer 2009 Feb;124(4):862-8

Department of Dermatology, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan.

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http://dx.doi.org/10.1002/ijc.24048DOI Listing
February 2009

Interstitial granulomatous dermatitis with plaques.

Eur J Dermatol 2008 Sep-Oct;18(5):600-1

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December 2008

Downregulated melanogenic paracrine cytokine linkages in hypopigmented palmoplantar skin.

Pigment Cell Melanoma Res 2008 Dec;21(6):687-99

Department of Dermatology, Shinshu University School of Medicine, Matsumoto, Japan 2 School of Bioscience and Biotechnology, Tokyo University of Technology, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1755-148x.2008.00492.xDOI Listing
December 2008

KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation.

Cell Signal 2008 Nov 10;20(11):1978-85. Epub 2008 Jul 10.

Molecular Cell Biology Laboratory, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba 6-3, Aramaki, Aoba-ku, Sendai 980-8578, Japan.

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http://dx.doi.org/10.1016/j.cellsig.2008.07.006DOI Listing
November 2008

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.

Nat Struct Mol Biol 2008 Nov 19;15(11):1138-46. Epub 2008 Oct 19.

Laboratory of DNA Damage Signaling, Department of Late Effect Studies, Radiation Biology Center, Kyoto University, Yoshidakonoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1038/nsmb.1504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293454PMC
November 2008