Publications by authors named "Minoru Horie"

100Publications

Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls.

Authors:
Roddy Walsh Najim Lahrouchi Rafik Tadros Florence Kyndt Charlotte Glinge Pieter G Postema Ahmad S Amin Eline A Nannenberg James S Ware Nicola Whiffin Francesco Mazzarotto Doris Škorić-Milosavljević Christian Krijger Elena Arbelo Dominique Babuty Hector Barajas-Martinez Britt M Beckmann Stéphane Bézieau J Martijn Bos Jeroen Breckpot Oscar Campuzano Silvia Castelletti Candan Celen Sebastian Clauss Anniek Corveleyn Lia Crotti Federica Dagradi Carlo de Asmundis Isabelle Denjoy Sven Dittmann Patrick T Ellinor Cristina Gil Ortuño Carla Giustetto Jean-Baptiste Gourraud Daisuke Hazeki Minoru Horie Taisuke Ishikawa Hideki Itoh Yoshiaki Kaneko Jørgen K Kanters Hiroki Kimoto Maria-Christina Kotta Ingrid P C Krapels Masahiko Kurabayashi Julieta Lazarte Antoine Leenhardt Bart L Loeys Catarina Lundin Takeru Makiyama Jacques Mansourati Raphaël P Martins Andrea Mazzanti Stellan Mörner Carlo Napolitano Kimie Ohkubo Michael Papadakis Boris Rudic Maria Sabater Molina Frédéric Sacher Hatice Sahin Georgia Sarquella-Brugada Regina Sebastiano Sanjay Sharma Mary N Sheppard Keiko Shimamoto M Benjamin Shoemaker Birgit Stallmeyer Johannes Steinfurt Yuji Tanaka David J Tester Keisuke Usuda Paul A van der Zwaag Sonia Van Dooren Lut Van Laer Annika Winbo Bo G Winkel Kenichiro Yamagata Sven Zumhagen Paul G A Volders Steven A Lubitz Charles Antzelevitch Pyotr G Platonov Katja E Odening Dan M Roden Jason D Roberts Jonathan R Skinner Jacob Tfelt-Hansen Maarten P van den Berg Morten S Olesen Pier D Lambiase Martin Borggrefe Kenshi Hayashi Annika Rydberg Tadashi Nakajima Masao Yoshinaga Johan B Saenen Stefan Kääb Pedro Brugada Tomas Robyns Daniela F Giachino Michael J Ackerman Ramon Brugada Josep Brugada Juan R Gimeno Can Hasdemir Pascale Guicheney Silvia G Priori Eric Schulze-Bahr Naomasa Makita Peter J Schwartz Wataru Shimizu Takeshi Aiba Jean-Jacques Schott Richard Redon Seiko Ohno Vincent Probst Elijah R Behr Julien Barc Connie R Bezzina

Genet Med 2020 Sep 7. Epub 2020 Sep 7.

Department of Clinical and Experimental Cardiology, Heart Centre, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.1038/s41436-020-00946-5DOI Listing
September 2020

Missense Mutation Causes Nonsense-Mediated mRNA Decay and Severe Dilated Cardiomyopathy.

Circ Genom Precis Med 2020 Oct 20;13(5):435-443. Epub 2020 Aug 20.

Department of Cardiovascular Medicine (K.K., S.O., M.F., T.O., M.H.), Shiga University of Medical Science, Otsu.

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http://dx.doi.org/10.1161/CIRCGEN.119.002853DOI Listing
October 2020

Cardiac Conduction Disorders as Markers of Cardiac Events in Myotonic Dystrophy Type 1.

J Am Heart Assoc 2020 Sep 19;9(17):e015709. Epub 2020 Aug 19.

Department of Neurology National Hospital Organization Osaka Toneyama Medical Center 5-1-1 Toyonaka Japan.

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http://dx.doi.org/10.1161/JAHA.119.015709DOI Listing
September 2020

An NGS-based genotyping in LQTS; minor genes are no longer minor.

J Hum Genet 2020 Jul 17. Epub 2020 Jul 17.

Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, Japan.

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http://dx.doi.org/10.1038/s10038-020-0805-zDOI Listing
July 2020

Postoperative supraventricular tachycardia and polymorphic ventricular tachycardia due to a novel SCN5A variant: a case report of a rare comorbidity that is difficult to diagnose.

BMC Cardiovasc Disord 2020 Jul 2;20(1):315. Epub 2020 Jul 2.

Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, 520-2192, Japan.

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http://dx.doi.org/10.1186/s12872-020-01601-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333335PMC
July 2020

Left-dominant arrhythmogenic cardiomyopathy with a nonsense mutation in DSP.

ESC Heart Fail 2020 Jun 27. Epub 2020 Jun 27.

Department of Cardiovascular Medicine and Diagnostic Radiology, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University, 1-1-1, Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.

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http://dx.doi.org/10.1002/ehf2.12790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524242PMC
June 2020

Telethonin variants found in Brugada syndrome, J-wave pattern ECG, and ARVC reduce peak Na 1.5 currents in HEK-293 cells.

Pacing Clin Electrophysiol 2020 Jun 25. Epub 2020 Jun 25.

Department of Medicine, Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, Indiana.

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http://dx.doi.org/10.1111/pace.13996DOI Listing
June 2020

Smoking habits and progression of coronary and aortic artery calcification: A 5-year follow-up of community-dwelling Japanese men.

Int J Cardiol 2020 Sep 8;314:89-94. Epub 2020 May 8.

Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Shiga, Japan; Department of Public Health, Shiga University of Medical Science, Shiga, Japan.

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http://dx.doi.org/10.1016/j.ijcard.2020.05.016DOI Listing
September 2020

Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome.

Authors:
Najim Lahrouchi Rafik Tadros Lia Crotti Yuka Mizusawa Pieter G Postema Leander Beekman Roddy Walsh Kanae Hasegawa Julien Barc Marko Ernsting Kari L Turkowski Andrea Mazzanti Britt M Beckmann Keiko Shimamoto Ulla-Britt Diamant Yanushi D Wijeyeratne Yu Kucho Tomas Robyns Taisuke Ishikawa Elena Arbelo Michael Christiansen Annika Winbo Reza Jabbari Steven A Lubitz Johannes Steinfurt Boris Rudic Bart Loeys M Ben Shoemaker Peter E Weeke Ryan Pfeiffer Brianna Davies Antoine Andorin Nynke Hofman Federica Dagradi Matteo Pedrazzini David J Tester J Martijn Bos Georgia Sarquella-Brugada Óscar Campuzano Pyotr G Platonov Birgit Stallmeyer Sven Zumhagen Eline A Nannenberg Jan H Veldink Leonard H van den Berg Ammar Al-Chalabi Christopher E Shaw Pamela J Shaw Karen E Morrison Peter M Andersen Martina Müller-Nurasyid Daniele Cusi Cristina Barlassina Pilar Galan Mark Lathrop Markus Munter Thomas Werge Marta Ribasés Tin Aung Chiea C Khor Mineo Ozaki Peter Lichtner Thomas Meitinger J Peter van Tintelen Yvonne Hoedemaekers Isabelle Denjoy Antoine Leenhardt Carlo Napolitano Wataru Shimizu Jean-Jacques Schott Jean-Baptiste Gourraud Takeru Makiyama Seiko Ohno Hideki Itoh Andrew D Krahn Charles Antzelevitch Dan M Roden Johan Saenen Martin Borggrefe Katja E Odening Patrick T Ellinor Jacob Tfelt-Hansen Jonathan R Skinner Maarten P van den Berg Morten Salling Olesen Josep Brugada Ramón Brugada Naomasa Makita Jeroen Breckpot Masao Yoshinaga Elijah R Behr Annika Rydberg Takeshi Aiba Stefan Kääb Silvia G Priori Pascale Guicheney Hanno L Tan Christopher Newton-Cheh Michael J Ackerman Peter J Schwartz Eric Schulze-Bahr Vincent Probst Minoru Horie Arthur A Wilde Michael W T Tanck Connie R Bezzina

Circulation 2020 Jul 20;142(4):324-338. Epub 2020 May 20.

Amsterdam UMC, University of Amsterdam, Heart Center; Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, The Netherlands (N.L., R.T., Y.M., P.G.P., L.B., R.W., N.H., H.L.T., A.A.W., C.R.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.120.045956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382531PMC
July 2020

Erratum to "Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients".

Stem Cells Int 2020 23;2020:8765895. Epub 2020 Jan 23.

Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1155/2020/8765895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204173PMC
January 2020

SCN5A mutation identified in a patient with short-coupled variant of torsades de pointes.

Pacing Clin Electrophysiol 2020 05 8;43(5):456-461. Epub 2020 May 8.

Department of Cardiovascular Medicine, Shiga University of Medical Science, Shiga, Japan.

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http://dx.doi.org/10.1111/pace.13924DOI Listing
May 2020

Identification of transmembrane protein 168 mutation in familial Brugada syndrome.

FASEB J 2020 May 16;34(5):6399-6417. Epub 2020 Mar 16.

Division of Molecular Medical Biochemistry, Department of Biochemistry and Molecular Biology, Shiga University of Medical Science, Otsu, Japan.

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http://dx.doi.org/10.1096/fj.201902991RDOI Listing
May 2020

High Prevalence of Late-Appearing T-Wave in Patients With Long QT Syndrome Type 8.

Circ J 2020 03 12;84(4):559-568. Epub 2020 Mar 12.

Department of Cardiovascular Medicine, Shiga University of Medical Science.

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http://dx.doi.org/10.1253/circj.CJ-19-1101DOI Listing
March 2020

Multivariate analysis of TU wave complex on electrocardiogram in Andersen-Tawil syndrome with KCNJ2 mutations.

Ann Noninvasive Electrocardiol 2020 05 14;25(3):e12721. Epub 2019 Nov 14.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Japan.

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http://dx.doi.org/10.1111/anec.12721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7358888PMC
May 2020

Clinical and neurophysiological variability in Andersen-Tawil syndrome.

Muscle Nerve 2019 12 9;60(6):752-757. Epub 2019 Oct 9.

Department of Neurology, Dokkyo Medical University, Tochigi, Japan.

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http://dx.doi.org/10.1002/mus.26705DOI Listing
December 2019

Long-term prognosis of patients withJ-wave syndrome.

Heart 2020 02 7;106(4):299-306. Epub 2019 Aug 7.

Division of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan

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http://dx.doi.org/10.1136/heartjnl-2019-315007DOI Listing
February 2020

Cardiac Arrest Associated with Both an Anomalous Left Coronary Artery and KCNE1 Polymorphism.

Int Heart J 2019 Jul 12;60(4):1003-1005. Epub 2019 Jul 12.

Department of Cardiology, Fujita Health University School of Medicine.

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http://dx.doi.org/10.1536/ihj.18-581DOI Listing
July 2019

Long QT syndrome with a de novo CALM2 mutation in a 4-year-old boy.

Pediatr Int 2019 Sep;61(9):852-858

Department of Pediatrics, Toyama Prefectural Central Hospital, Toyama, Japan.

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http://dx.doi.org/10.1111/ped.13959DOI Listing
September 2019

A de novo gain-of-function KCND3 mutation in early repolarization syndrome.

Heart Rhythm 2019 11 4;16(11):1698-1706. Epub 2019 Jun 4.

Department of Cardiovascular Medicine, Shiga University of Medical Science, Otsu, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2019.05.033DOI Listing
November 2019

Left-Dominant Arrhythmogenic Cardiomyopathy With Heterozygous Mutations in DSP and MYBPC3.

Circ Cardiovasc Imaging 2019 06 30;12(6):e008913. Epub 2019 May 30.

Department of Cardiology, Asahikawa Medical University (N. Sakamoto, S.H., A.M., K.A., N. Sato, N.H.).

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http://dx.doi.org/10.1161/CIRCIMAGING.119.008913DOI Listing
June 2019

Optical Recording of Action Potentials in Human Induced Pluripotent Stem Cell-Derived Cardiac Single Cells and Monolayers Generated from Long QT Syndrome Type 1 Patients.

Stem Cells Int 2019 6;2019:7532657. Epub 2019 Mar 6.

Department of Cell Growth and Differentiation, Center for iPS Cell Research and Application, Kyoto University, Sakyo-ku, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1155/2019/7532657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431403PMC
March 2019

Association between lymphocyte count and neurological outcomes in post-cardiac arrest patients treated with mild therapeutic hypothermia.

Acute Med Surg 2019 Jan 4;6(1):30-39. Epub 2018 Oct 4.

Department of Critical and Intensive Care Medicine Shiga University of Medical Science Otsu Japan.

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http://dx.doi.org/10.1002/ams2.374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328908PMC
January 2019

Identification of a novel exon3 deletion of RYR2 in a family with catecholaminergic polymorphic ventricular tachycardia.

Ann Noninvasive Electrocardiol 2019 05 7;24(3):e12623. Epub 2019 Jan 7.

Department of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan.

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http://dx.doi.org/10.1111/anec.12623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6850420PMC
May 2019

A trafficking-deficient KCNQ1 mutation, T587M, causes a severe phenotype of long QT syndrome by interfering with intracellular hERG transport.

J Cardiol 2019 05 24;73(5):343-350. Epub 2018 Dec 24.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09145087183035
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http://dx.doi.org/10.1016/j.jjcc.2018.10.011DOI Listing
May 2019

Dynamic QT Changes in Long QT Syndrome Type 8.

Circ J 2019 06 22;83(7):1614. Epub 2018 Dec 22.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science.

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http://dx.doi.org/10.1253/circj.CJ-18-0984DOI Listing
June 2019

Medical Castration is a Rare but Possible Trigger of Torsade de Pointes and Ventricular Fibrillation.

Int Heart J 2019 Jan 5;60(1):193-198. Epub 2018 Dec 5.

Department of Cardiovascular Medicine, Faculty of Medical Sciences, University of Fukui.

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https://www.jstage.jst.go.jp/article/ihj/advpub/0/advpub_18-
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http://dx.doi.org/10.1536/ihj.18-127DOI Listing
January 2019

Electrical disorders in atrial septal defect: genetics and heritability.

J Thorac Dis 2018 Sep;10(Suppl 24):S2848-S2853

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Ohtsu, Shiga, Japan.

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http://dx.doi.org/10.21037/jtd.2018.02.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174139PMC
September 2018

A tryptophan residue in the caffeine-binding site of the ryanodine receptor regulates Ca sensitivity.

Commun Biol 2018 23;1:98. Epub 2018 Jul 23.

Department of Cellular and Molecular Pharmacology, Juntendo University Graduate School of Medicine, Tokyo, 113-8421, Japan.

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http://dx.doi.org/10.1038/s42003-018-0103-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123685PMC
July 2018

Extensive Diversity of Molecular Mechanisms Underlying the Congenital Long QT Syndrome Type 1.

Authors:
Minoru Horie

Can J Cardiol 2018 09 1;34(9):1108-1109. Epub 2018 Aug 1.

Department of Cardiovascular Medicine, Shiga University of Medical Science, Shiga, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2018.07.474DOI Listing
September 2018

A novel mutation identified in a patient with Timothy syndrome without syndactyly exerts both marked loss- and gain-of-function effects.

HeartRhythm Case Rep 2018 Jul 31;4(7):273-277. Epub 2018 Mar 31.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S22140271183004
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http://dx.doi.org/10.1016/j.hrcr.2018.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050422PMC
July 2018

Electrical storm in an infant with short-coupled variant of torsade de pointes.

J Arrhythm 2018 Jun 14;34(3):315-318. Epub 2018 May 14.

Department of Cardiovascular and Respiratory Medicine Shiga University of Medical Science Otsu Shiga Japan.

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http://dx.doi.org/10.1002/joa3.12071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009772PMC
June 2018

Three cases of catecholaminergic polymorphic ventricular tachycardia with prolonged QT intervals including two cases of compound mutations.

J Arrhythm 2018 Jun 6;34(3):291-293. Epub 2018 Apr 6.

Department of Pediatrics National Hospital Organization Kagoshima Medical Center Kagoshima Japan.

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http://dx.doi.org/10.1002/joa3.12053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010000PMC
June 2018

Differential Diagnosis Between Catecholaminergic Polymorphic Ventricular Tachycardia and Long QT Syndrome Type 1 - Modified Schwartz Score.

Circ J 2018 08 21;82(9):2269-2276. Epub 2018 Jun 21.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science.

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http://dx.doi.org/10.1253/circj.CJ-17-1032DOI Listing
August 2018

Relationship of serum irisin levels to prevalence and progression of coronary artery calcification: A prospective, population-based study.

Int J Cardiol 2018 Sep 23;267:177-182. Epub 2018 May 23.

Department of Public Health, Shiga University of Medical Science, Otsu, Japan; Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, Japan.

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http://dx.doi.org/10.1016/j.ijcard.2018.05.075DOI Listing
September 2018

Serum magnesium, phosphorus, and calcium levels and subclinical calcific aortic valve disease: A population-based study.

Atherosclerosis 2018 06 22;273:145-152. Epub 2018 Mar 22.

Department of Public Health, Shiga University of Medical Science, Otsu, Japan; Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, Japan.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.03.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991478PMC
June 2018

Copy number variations of SCN5A in Brugada syndrome.

Heart Rhythm 2018 08 21;15(8):1179-1188. Epub 2018 Mar 21.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2018.03.033DOI Listing
August 2018

Population pharmacokinetics and pharmacogenomics of apixaban in Japanese adult patients with atrial fibrillation.

Br J Clin Pharmacol 2018 06 16;84(6):1301-1312. Epub 2018 Apr 16.

Laboratory of Clinical Pharmaceutics and Therapeutics, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-higashi, Kusatsu, Shiga, 525-8577, Japan.

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http://dx.doi.org/10.1111/bcp.13561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980466PMC
June 2018

A challenge for mutation specific risk stratification in long QT syndrome type 1.

J Cardiol 2018 07 10;72(1):56-65. Epub 2018 Feb 10.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Japan; Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jjcc.2017.12.011DOI Listing
July 2018

Bradycardia Is a Specific Phenotype of Catecholaminergic Polymorphic Ventricular Tachycardia Induced by RYR2 Mutations.

Intern Med 2018 Jul 9;57(13):1813-1817. Epub 2018 Feb 9.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Japan.

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http://dx.doi.org/10.2169/internalmedicine.9843-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064684PMC
July 2018

Restoration of mutant hERG stability by inhibition of HDAC6.

J Mol Cell Cardiol 2018 02 4;115:158-169. Epub 2018 Feb 4.

Department of Genetic Medicine and Regenerative Therapeutics, Institute of Regenerative Medicine and Biofunction, Tottori University, 86-1, Nishimachi, Yonago, Tottori 683-8503, Japan.

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http://dx.doi.org/10.1016/j.yjmcc.2018.01.009DOI Listing
February 2018

Unique genetic background and outcome of non-Caucasian Japanese probands with arrhythmogenic right ventricular dysplasia/cardiomyopathy.

Mol Genet Genomic Med 2017 11 13;5(6):639-651. Epub 2017 Aug 13.

Department of Cardiovascular Medicine, Shiga University of Medical Science, Otsu, Japan.

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http://doi.wiley.com/10.1002/mgg3.311
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http://dx.doi.org/10.1002/mgg3.311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702570PMC
November 2017

Novel intracellular transport-refractory mutations in KCNH2 identified in patients with symptomatic long QT syndrome.

J Cardiol 2018 04 14;71(4):401-408. Epub 2017 Nov 14.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan; Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, Shiga, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jjcc.2017.10.004DOI Listing
April 2018

Macro-pro-B-type natriuretic peptide (proBNP) and hidden macro-N-terminal proBNP: Case report.

Clin Biochem 2018 Feb 2;52:148-152. Epub 2017 Nov 2.

Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.1016/j.clinbiochem.2017.10.019DOI Listing
February 2018

Impact of ABCB1, ABCG2, and CYP3A5 polymorphisms on plasma trough concentrations of apixaban in Japanese patients with atrial fibrillation.

Pharmacogenet Genomics 2017 Sep;27(9):329-336

aLaboratory of Clinical Pharmaceutics and Therapeutics, College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu bDepartment of Pharmacy cDepartment of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Japan.

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http://dx.doi.org/10.1097/FPC.0000000000000294DOI Listing
September 2017

Drug-induced fatal arrhythmias: Acquired long QT and Brugada syndromes.

Pharmacol Ther 2017 Aug 18;176:48-59. Epub 2017 May 18.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2017.05.001DOI Listing
August 2017

Long QT syndrome presents not only as QT prolongation but also as abnormal T-wave morphology.

Authors:
Minoru Horie

Heart Rhythm 2017 08 25;14(8):1171-1172. Epub 2017 Apr 25.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2017.04.032DOI Listing
August 2017

J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge.

Europace 2017 04;19(4):665-694

Heart Center, Department of Clinical and Experimental Cardiology, Academic Medical Center, University of Amsterdam, the Netherlands and Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders, Jeddah, Kingdom of Saudi Arabia.

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http://dx.doi.org/10.1093/europace/euw235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834028PMC
April 2017

Quantitative analysis of PKP2 and neighbouring genes in a patient with arrhythmogenic right ventricular cardiomyopathy caused by heterozygous PKP2 deletion.

Europace 2017 Apr;19(4):644-650

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Tsukiwa-cho, Seta, Otsu 520-2192, Japan.

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http://dx.doi.org/10.1093/europace/euw038DOI Listing
April 2017

Genotype-Phenotype Correlation of Mutation for the Clinical and Electrocardiographic Characteristics of Probands With Brugada Syndrome: A Japanese Multicenter Registry.

Circulation 2017 Jun 24;135(23):2255-2270. Epub 2017 Mar 24.

From Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan (K.Y., T.A., K.K., S.K. S.Y., H.O., W.S.); Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Japan (M.H., S. Ohno); Department of Cardiovascular Medicine, University of Tokyo, Japan (K.Y.); Department of Cardiopulmonary Medicine, Keio University, Tokyo, Japan (S. Ogawa, K.F.); Division of Cardiology, Niigata University Graduate School of Medical and Dental Sciences, Japan (Y.A., H.W.); Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan (T.O., H.M.); Division of Cardiovascular Medicine, Kanazawa University Graduate School of Medicine, Ishikawa, Japan (M.Y., K.H.); Molecular Physiology, Nagasaki University Graduate School of Biomedical Sciences, Japan (N.M.); Department of Cardiology, Tokyo Metropolitan Hiroo Hospital, Japan (H.S.); Department of Human Genetics and Disease Diversity, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan (T.T.); Division of Cardiology, Yamaguchi University Graduate School of Medicine, Japan (A.S.); Department of Cardiology, Tokyo Women's Medical University, Japan (N.H.); Department of Cardiology, St Marianna University of Medicine, Kanagawa, Japan (R.K.); Department of Cardiovascular Medicine, Hiroshima University, Japan (Y.N.); Department of Cardiovascular Medicine, Osaka City University, Japan (M.T.); Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Japan (T.M.); Laboratory of Molecular Genetics, National Cerebral and Cardiovascular Center, Osaka, Japan (Y.M.); Departments of Cardiovascular Diseases, Pediatrics, and Molecular Pharmacology & Experimental Therapeutics; Divisions of Heart Rhythm Services and Pediatric Cardiology, Windland Smith Rice Sudden Death Genomics Laboratory, Mayo Clinic, Rochester, MN (J.D.K., M.J.A.); and Department of Cardiovascular Medicine, Nippon Medical School, Tokyo, Japan (W.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.027983DOI Listing
June 2017

The relationship between J waves and contact of lung cancer with the heart.

Ann Noninvasive Electrocardiol 2017 Sep 16;22(5). Epub 2017 Mar 16.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Otsu City, Shiga, Japan.

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http://doi.wiley.com/10.1111/anec.12433
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http://dx.doi.org/10.1111/anec.12433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931450PMC
September 2017

Cardiac conduction defects and Brugada syndrome: A family with overlap syndrome carrying a nonsense SCN5A mutation.

J Arrhythm 2017 Feb 2;33(1):35-39. Epub 2016 Jul 2.

Department of Cardiovascular and Respiratory Medicine, Shiga University of Medical Science, Ohtsu, Shiga, Japan.

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http://dx.doi.org/10.1016/j.joa.2016.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300865PMC
February 2017