Mingyan Zhu

Mingyan Zhu

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Mingyan Zhu

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GAS5/miR-21 Axis as a Potential Target to Rescue ZCL-082-Induced Autophagy of Female Germline Stem Cells In Vitro.

Mol Ther Nucleic Acids 2019 Sep 28;17:436-447. Epub 2019 Jun 28.

Key Laboratory of Fertility Preservation and Maintenance of Ministry of Education, Ningxia Medical University, Yinchuan 750004, China; Key Laboratory for the Genetics of Developmental & Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2019.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637212PMC
September 2019

Establishment of prognostic scoring models for different etiologies of acute decompensation in hospitalized patients with cirrhosis.

J Int Med Res 2019 Sep 31;47(9):4492-4504. Epub 2019 Jul 31.

Department of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

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http://dx.doi.org/10.1177/0300060519862065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753578PMC
September 2019

USP8 Deubiquitinates the Leptin Receptor and Is Necessary for Leptin-Mediated Synapse Formation.

Endocrinology 2019 Aug;160(8):1982-1998

Department of Integrated Physiology and Neuroscience, Washington State University, Pullman, Washington.

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http://dx.doi.org/10.1210/en.2019-00107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660906PMC
August 2019

Design, Synthesis, and Structure-Activity Relationship of 7-Propanamide Benzoxaboroles as Potent Anticancer Agents.

J Med Chem 2019 Jul 2;62(14):6765-6784. Epub 2019 Jul 2.

State Key Laboratory of Microbial Metabolism, School of Pharmacy , Shanghai Jiao Tong University , 200240 Shanghai , China.

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http://dx.doi.org/10.1021/acs.jmedchem.9b00736DOI Listing
July 2019

C89 Induces Autophagy of Female Germline Stem Cells via Inhibition of the PI3K-Akt Pathway In Vitro.

Cells 2019 06 18;8(6). Epub 2019 Jun 18.

Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Bio-X Institutes, School of Medicine, Shanghai Jiao Tong University, Shanghai 200240, China.

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http://dx.doi.org/10.3390/cells8060606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627605PMC
June 2019

Optical Control of the GTP Affinity of K-Ras(G12C) by a Photoswitchable Inhibitor.

Chembiochem 2019 Jun 20. Epub 2019 Jun 20.

School of Pharmacy, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang District, Shanghai, 200240, P. R. China.

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http://dx.doi.org/10.1002/cbic.201900342DOI Listing
June 2019

Microbial Infections as a Trigger for Acute-on-Chronic Liver Failure: A Review.

Med Sci Monit 2019 Jun 27;25:4773-4783. Epub 2019 Jun 27.

Department of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China (mainland).

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https://www.medscimonit.com/abstract/index/idArt/915637
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http://dx.doi.org/10.12659/MSM.915637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611219PMC
June 2019

Effects of acute and chronic nicotine on catecholamine neurons of the nucleus of the solitary tract.

Am J Physiol Regul Integr Comp Physiol 2019 Jan 24;316(1):R38-R49. Epub 2018 Oct 24.

Program in Neuroscience, Department of Integrative Physiology and Neuroscience, Washington State University , Pullman, Washington.

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https://www.physiology.org/doi/10.1152/ajpregu.00344.2017
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http://dx.doi.org/10.1152/ajpregu.00344.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383491PMC
January 2019

Azobenzene-based small molecular photoswitches for protein modulation.

Org Biomol Chem 2018 11;16(44):8434-8445

State Key Laboratory of Microbial Metabolism, School of Pharmacy, Shanghai Jiao Tong University, 800 Dongchuan Road, Minhang District, Shanghai 200240, China.

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http://xlink.rsc.org/?DOI=C8OB02157K
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http://dx.doi.org/10.1039/c8ob02157kDOI Listing
November 2018

MicroRNA-30b targets Snail to impede epithelial-mesenchymal transition in pancreatic cancer stem cells.

J Cancer 2018 25;9(12):2147-2159. Epub 2018 May 25.

General Surgery Department, the First Affiliated Hospital of Soochow University, 215006, Suzhou, Jiangsu, P.R. China.

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http://dx.doi.org/10.7150/jca.25006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010678PMC
May 2018

Synthesis of biologically active boron-containing compounds.

Medchemcomm 2018 Feb 28;9(2):201-211. Epub 2017 Nov 28.

State Key Laboratory of Microbial Metabolism , School of Pharmacy , Shanghai Jiao Tong University , 800 Dongchuan Road, Minhang District , Shanghai 200240 , China . Email: ; ; Tel: +86 21 34206721.

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http://dx.doi.org/10.1039/c7md00552kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083787PMC
February 2018

High glucose increases action potential firing of catecholamine neurons in the nucleus of the solitary tract by increasing spontaneous glutamate inputs.

Am J Physiol Regul Integr Comp Physiol 2017 Sep 14;313(3):R229-R239. Epub 2017 Jun 14.

Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, Washington

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http://www.physiology.org/doi/10.1152/ajpregu.00413.2016
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http://dx.doi.org/10.1152/ajpregu.00413.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625278PMC
September 2017

Development of a highly reliable assay for ubiquitin-specific protease 2 inhibitors.

Bioorg Med Chem Lett 2017 09 23;27(17):4015-4018. Epub 2017 Jul 23.

State Key Laboratory of Microbial Metabolism, School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.07.059DOI Listing
September 2017

Chalcone-benzoxaborole hybrids as novel anticancer agents.

Bioorg Med Chem Lett 2016 12 12;26(23):5797-5801. Epub 2016 Oct 12.

State Key Laboratory of Microbial Metabolism, School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China; Chemical Biology Division of Shanghai Universities E-Institutes, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2016.10.024DOI Listing
December 2016

Salidroside induces apoptosis and autophagy in human colorectal cancer cells through inhibition of PI3K/Akt/mTOR pathway.

Oncol Rep 2016 Dec 30;36(6):3559-3567. Epub 2016 Sep 30.

Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, P.R. China.

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http://dx.doi.org/10.3892/or.2016.5138DOI Listing
December 2016

3D Culture of MIN-6 Cells on Decellularized Pancreatic Scaffold: In Vitro and In Vivo Study.

Biomed Res Int 2015 24;2015:432645. Epub 2015 Nov 24.

Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu 226001, China.

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http://dx.doi.org/10.1155/2015/432645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672115PMC
September 2016

The dynamic three-dimensional culture of islet-like clusters in decellularized liver scaffolds.

Cell Tissue Res 2016 07 21;365(1):157-71. Epub 2016 Jan 21.

Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, China.

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http://dx.doi.org/10.1007/s00441-015-2356-8DOI Listing
July 2016

Decellularization and Recellularization of Rat Livers With Hepatocytes and Endothelial Progenitor Cells.

Artif Organs 2016 Mar 4;40(3):E25-38. Epub 2015 Dec 4.

Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, China.

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http://dx.doi.org/10.1111/aor.12645DOI Listing
March 2016

Upregulated expression of polycomb protein Ring1 contributes to poor prognosis and accelerated proliferation in human hepatocellular carcinoma.

Tumour Biol 2015 Dec 4;36(12):9579-88. Epub 2015 Jul 4.

Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, 226001, China.

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http://dx.doi.org/10.1007/s13277-015-3721-7DOI Listing
December 2015

Three-dimensional culture of mouse pancreatic islet on a liver-derived perfusion-decellularized bioscaffold for potential clinical application.

J Biomater Appl 2015 Oct 25;30(4):379-87. Epub 2015 May 25.

Department of General Surgery, Affiliated Hospital of Nantong University, Jiangsu, People's Republic of China Surgical Comprehensive Laboratory, Affiliated Hospital of Nantong University, Jiangsu, People's Republic of China

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http://dx.doi.org/10.1177/0885328215587610DOI Listing
October 2015

Controlling the blood glucose of type 1 diabetes mice by co-culturing MIN-6 β cells on 3D scaffold.

Pediatr Transplant 2015 Jun 10;19(4):371-9. Epub 2015 Feb 10.

Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China; Department of General Surgery, Tenth People's Hospital of Tongji University, Shanghai, China.

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http://dx.doi.org/10.1111/petr.12443DOI Listing
June 2015

Frequency-dependent facilitation of synaptic throughput via postsynaptic NMDA receptors in the nucleus of the solitary tract.

J Physiol 2015 Jan 3;593(1):111-25. Epub 2014 Nov 3.

Program in Neuroscience, Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, WA, 99164, USA.

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http://dx.doi.org/10.1113/jphysiol.2013.258103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293058PMC
January 2015

The downregulation of ErbB3 binding protein 1 (EBP1) is associated with poor prognosis and enhanced cell proliferation in hepatocellular carcinoma.

Mol Cell Biochem 2014 Nov 1;396(1-2):175-85. Epub 2014 Aug 1.

Basic Medical Research Centre, Medical College, Nantong University, Nantong, 226001, China.

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http://dx.doi.org/10.1007/s11010-014-2153-9DOI Listing
November 2014

The procognitive and synaptogenic effects of angiotensin IV-derived peptides are dependent on activation of the hepatocyte growth factor/c-met system.

J Pharmacol Exp Ther 2014 Nov 3;351(2):390-402. Epub 2014 Sep 3.

Department of Integrative Physiology and Neuroscience (C.C.B., L.H.K., M.Z., K.A.T., L.S., S.M.A., J.W.W., G.A.W., J.W.H.) and Department of Psychology (J.W.W., J.W.H.), Washington State University, Pullman, Washington; and M Biotechnology, Inc., Seattle, Washington (L.H.K., J.W.W., J.W.H.)

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http://dx.doi.org/10.1124/jpet.114.218735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201273PMC
November 2014

Leptin potentiates GABAergic synaptic transmission in the developing rodent hippocampus.

Front Cell Neurosci 2014 15;8:235. Epub 2014 Aug 15.

Parc Scientifique de Luminy, Aix-Marseille Université Marseille, France ; Unité 901, Institut National de la Santé et de la Recherche Médicale Marseille, France ; Institut de Neurobiologie de la Méditerranée Marseille, France.

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http://dx.doi.org/10.3389/fncel.2014.00235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133691PMC
September 2014

Hindbrain oxytocin receptors contribute to the effects of circulating oxytocin on food intake in male rats.

Endocrinology 2014 Aug 30;155(8):2845-57. Epub 2014 May 30.

Research and Development Service (J.M.H., V.T.A., B.W.T., R.W.C., B.H.H., D.G.B., J.E.B.), Veterans Affairs Puget Sound Health Care System, Seattle, Washington 98108; Department of Medicine (J.M.H., G.J.M., M.W.S., D.G.B., J.E.B.), Division of Metabolism, Endocrinology, and Nutrition, and Diabetes and Obesity Center of Excellence (G.J.M., M.W.S.), Department of Medicine, University of Washington, Seattle, Washington 98195; Program in Neuroscience (M.Z., S.M.A.), Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, Washington 99164.

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http://dx.doi.org/10.1210/en.2014-1148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098005PMC
August 2014

Leptin induces hippocampal synaptogenesis via CREB-regulated microRNA-132 suppression of p250GAP.

Mol Endocrinol 2014 Jul 30;28(7):1073-87. Epub 2014 May 30.

Department of Integrative Physiology and Neuroscience (M.D., M.Z., T.J.L., T.B., I.N.K., S.M.A., G.A.W.), Program in Neuroscience, Washington State University, Pullman, Washington 99164; Oregon Stem Cell Center (S.I.), Oregon Health and Sciences University, Portland, Oregon 97239; and Department of Neurophysiology (T.N.), Graduate School of Medicine, University of Tokyo, Tokyo 113-0033 Japan.

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http://dx.doi.org/10.1210/me.2013-1332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4075163PMC
July 2014

Leptin-induced spine formation requires TrpC channels and the CaM kinase cascade in the hippocampus.

J Neurosci 2014 Jul;34(30):10022-33

Department of Integrative Physiology and Neuroscience, and Program in Neuroscience, Washington State University, Pullman, Washington 99164, and

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http://dx.doi.org/10.1523/JNEUROSCI.2868-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107395PMC
July 2014

Differentiation of iPSCs into insulin-producing cells via adenoviral transfection of PDX-1, NeuroD1 and MafA.

Diabetes Res Clin Pract 2014 Jun 1;104(3):383-92. Epub 2014 Apr 1.

Department of General Surgery, Affiliated Hospital of Nantong University, Nantong University, 226001 Nantong, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.diabres.2014.03.017DOI Listing
June 2014

FAM3A activates PI3K p110α/Akt signaling to ameliorate hepatic gluconeogenesis and lipogenesis.

Hepatology 2014 May 27;59(5):1779-90. Epub 2014 Mar 27.

Department of Physiology and Pathophysiology, Key Laboratory of Molecular Cardiovascular Science of the Ministry of Education, Peking University Health Science Center, Beijing, China.

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http://dx.doi.org/10.1002/hep.26945DOI Listing
May 2014

MiR-200a inhibits epithelial-mesenchymal transition of pancreatic cancer stem cell.

BMC Cancer 2014 Feb 12;14:85. Epub 2014 Feb 12.

Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province 226001, P, R, China.

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http://dx.doi.org/10.1186/1471-2407-14-85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923443PMC
February 2014

A genome-wide screen of CREB occupancy identifies the RhoA inhibitors Par6C and Rnd3 as regulators of BDNF-induced synaptogenesis.

PLoS One 2013 6;8(6):e64658. Epub 2013 Jun 6.

Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, Program in Neuroscience, Washington State University, Pullman, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0064658PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675129PMC
January 2014

The environmental neurotoxicant PCB 95 promotes synaptogenesis via ryanodine receptor-dependent miR132 upregulation.

J Neurosci 2014 Jan;34(3):717-25

Integrative Physiology and Neuroscience, Washington State University, Pullman, Washington 99164, Department of Molecular Biosciences, University of California, Davis, California 95616, and Oregon Stem Cell Center, Oregon Health and Science University, Portland, Oregon 97239.

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http://dx.doi.org/10.1523/JNEUROSCI.2884-13.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891953PMC
January 2014

Knockdown of Oct4 and Nanog expression inhibits the stemness of pancreatic cancer cells.

Cancer Lett 2013 Oct 17;340(1):113-23. Epub 2013 Jul 17.

Surgical Comprehensive Laboratory, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province 226001, PR China; Department of General Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province 226001, PR China; Visitor Scholar of Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.

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http://dx.doi.org/10.1016/j.canlet.2013.07.009DOI Listing
October 2013

Evaluation of metabolically stabilized angiotensin IV analogs as procognitive/antidementia agents.

J Pharmacol Exp Ther 2013 Jan 10;344(1):141-54. Epub 2012 Oct 10.

Department of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, P.O. Box 6520, Washington State University, Pullman, WA 99164-6520, USA.

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http://dx.doi.org/10.1124/jpet.112.199497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533412PMC
January 2013

Serotonin activates catecholamine neurons in the solitary tract nucleus by increasing spontaneous glutamate inputs.

J Neurosci 2012 Nov;32(46):16530-8

Program in Neuroscience, Department of Veterinary Comparative Anatomy, Physiology and Pharmacology, Washington State University, Pullman, Washington 99164, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1372-12.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752146PMC
November 2012

Comparing the reprogramming efficiency of mouse embryonic fibroblasts, mouse bone marrow mesenchymal stem cells and bone marrow mononuclear cells to iPSCs.

In Vitro Cell Dev Biol Anim 2012 Apr 29;48(4):236-43. Epub 2012 Mar 29.

Department of General Surgery, Affiliated Hospital of Nantong University, Nantong University, Nantong, People's Republic of China.

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http://dx.doi.org/10.1007/s11626-012-9493-0DOI Listing
April 2012

Construction of polyheterocyclic benzopyran library with diverse core skeletons through diversity-oriented synthesis pathway: part II.

ACS Comb Sci 2012 Feb 30;14(2):124-34. Epub 2011 Dec 30.

Department of Chemistry, Seoul National University, Korea.

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http://dx.doi.org/10.1021/co2001907DOI Listing
February 2012

Facilitation of hippocampal synaptogenesis and spatial memory by C-terminal truncated Nle1-angiotensin IV analogs.

J Pharmacol Exp Ther 2011 Oct 30;339(1):35-44. Epub 2011 Jun 30.

Department of Veterinary and Comparative, Washington State University, Pullman, Washington 99164-6520, USA.

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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.111.18222
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http://dx.doi.org/10.1124/jpet.111.182220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186286PMC
October 2011

Effects of intrahepatic bone-derived mesenchymal stem cells autotransplantation on the diabetic Beagle dogs.

J Surg Res 2011 Jun 29;168(2):213-23. Epub 2009 Oct 29.

Department of General Surgery, The Affiliated Hospital, Nantong University, Nantong, Jiangsu Province, People's Republic of China.

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http://dx.doi.org/10.1016/j.jss.2009.10.008DOI Listing
June 2011

Discovery of novel benzopyranyl tetracycles that act as inhibitors of osteoclastogenesis induced by receptor activator of NF-κB ligand.

J Med Chem 2010 Dec 29;53(24):8760-4. Epub 2010 Nov 29.

Department of Chemistry, Seoul National University, Seoul 151-747, Korea.

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http://pubs.acs.org/doi/abs/10.1021/jm1011269
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http://dx.doi.org/10.1021/jm1011269DOI Listing
December 2010

Activation of delta-opioid receptors reduces excitatory input to putative gustatory cells within the nucleus of the solitary tract.

J Neurophysiol 2009 Jan 19;101(1):258-68. Epub 2008 Nov 19.

Department of Anatomy, Southern Illinois University School of Medicine, Life Science III Room 2073, 1135 Lincoln Dr., Carbondale, IL 62901, USA.

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http://dx.doi.org/10.1152/jn.90648.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637018PMC
January 2009

Human bone marrow mesenchymal stem cells transfected with human insulin genes can secrete insulin stably.

Ann Clin Lab Sci 2006 ;36(2):127-36

Depatment of General Surgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, China, 2226001.

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June 2006

Olfactory nerve-evoked, metabotropic glutamate receptor-mediated synaptic responses in rat olfactory bulb mitral cells.

J Neurophysiol 2006 Apr 4;95(4):2233-41. Epub 2006 Jan 4.

Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, TN 38163, USA.

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http://www.physiology.org/doi/10.1152/jn.01150.2005
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http://dx.doi.org/10.1152/jn.01150.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366052PMC
April 2006

Angiotensin AT1 receptor signalling pathways in neurons.

Clin Exp Pharmacol Physiol 2002 May-Jun;29(5-6):483-90

Department of Physiology, College of Medicine and McKnight Brain Institute, University of Florida, Gainesville, Florida 32610, USA.

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http://dx.doi.org/10.1046/j.1440-1681.2002.03660.xDOI Listing
August 2002