Publications by authors named "Mingxing Ouyang"

31Publications

Optogenetic Control for Investigating Subcellular Localization of Fyn Kinase Activity in Single Live Cells.

J Mol Biol 2020 Mar 18;432(7):1901-1909. Epub 2020 Mar 18.

Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA; Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2020.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225052PMC
March 2020

Cell motion-coordinated fibrillar assembly of soluble collagen I to promote MDCK cell branching formation.

Biochem Biophys Res Commun 2020 Apr 26;524(2):317-324. Epub 2020 Jan 26.

Institute of Biomedical Engineering and Health Sciences, College of Pharmaceutical Engineering and Life Science, Changzhou University, 1 Gehu Road, Wujin District, Changzhou City, Jiangsu Province, 213164, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2020.01.019DOI Listing
April 2020

Visualizing Spatiotemporal Dynamics of Intercellular Mechanotransmission upon Wounding.

ACS Photonics 2018 Sep 20;5(9):3565-3574. Epub 2018 Aug 20.

Department of Bioengineering, University of California, San Diego, La Jolla, California 92093, United States.

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http://dx.doi.org/10.1021/acsphotonics.8b00383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502247PMC
September 2018

Sensitive FRET Biosensor Reveals Fyn Kinase Regulation by Submembrane Localization.

ACS Sens 2019 01 9;4(1):76-86. Epub 2019 Jan 9.

Department of Bioengineering , University of California at San Diego , La Jolla , California 92093 , United States.

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http://pubs.acs.org/doi/10.1021/acssensors.8b00896
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http://dx.doi.org/10.1021/acssensors.8b00896DOI Listing
January 2019

Engineered proteins with sensing and activating modules for automated reprogramming of cellular functions.

Nat Commun 2017 09 7;8(1):477. Epub 2017 Sep 7.

Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.

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http://dx.doi.org/10.1038/s41467-017-00569-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589908PMC
September 2017

Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity.

J Cell Biol 2016 05;213(3):371-83

Yale Cardiovascular Research Center, Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, CT 06511 Department of Cell Biology, Yale University, New Haven, CT 06520 Department of Biomedical Engineering, Yale University, New Haven, CT 06520

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http://dx.doi.org/10.1083/jcb.201510012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4862330PMC
May 2016

RhoA and membrane fluidity mediates the spatially polarized Src/FAK activation in response to shear stress.

Sci Rep 2014 Nov 12;4:7008. Epub 2014 Nov 12.

1] Department of Bioengineering and the Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA [2] Department of Integrative and Molecular Physiology, Center for Biophysics and Computational Biology, Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA [3] Department of Bioengineering, University of California at San Diego, CA 92093, USA.

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http://dx.doi.org/10.1038/srep07008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4228346PMC
November 2014

Electroporation-delivered fluorescent protein biosensors for probing molecular activities in cells without genetic encoding.

Chem Commun (Camb) 2014 Oct;50(78):11536-9

School of Biomedical Engineering and Sciences, Virginia Tech-Wake Forest University, Blacksburg, Virginia 24061, USA.

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http://dx.doi.org/10.1039/c4cc04730cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5783554PMC
October 2014

Decipher the dynamic coordination between enzymatic activity and structural modulation at focal adhesions in living cells.

Sci Rep 2014 Jul 24;4:5756. Epub 2014 Jul 24.

1] Department of Bioengineering, Institute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093-0435 [2] Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801 [3] Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL 61801 [4] Center of Biophysics and Computational Biology, Beckman Institute for Advanced Science and Technology, Department of Molecular and Integrative Physiology and, University of Illinois at Urbana-Champaign, Urbana, IL 61801.

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http://www.nature.com/articles/srep05756
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http://dx.doi.org/10.1038/srep05756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108961PMC
July 2014

Genetically encoded fluorescent biosensors for live-cell imaging of MT1-MMP protease activity.

Methods Mol Biol 2014 ;1071:163-74

Department of Bioengineering, University of Illinois at Urbana-Champaign, Champaign, IL, USA.

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http://dx.doi.org/10.1007/978-1-62703-622-1_13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550515PMC
April 2014

Integrins in mechanotransduction.

Curr Opin Cell Biol 2013 Oct 21;25(5):613-8. Epub 2013 Jun 21.

Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, United States.

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http://dx.doi.org/10.1016/j.ceb.2013.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757118PMC
October 2013

Antagonism between binding site affinity and conformational dynamics tunes alternative cis-interactions within Shp2.

Nat Commun 2013 ;4:2037

Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1038/ncomms3037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777412PMC
December 2013

Long-range mechanical force enables self-assembly of epithelial tubular patterns.

Proc Natl Acad Sci U S A 2012 Apr 16;109(15):5576-82. Epub 2012 Mar 16.

Bioengineering, California Institute of Technology, MS 138-78, 1200 East California Boulevard, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.1114781109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326479PMC
April 2012

Wide-field optical sectioning for live-tissue imaging by plane-projection multiphoton microscopy.

J Biomed Opt 2011 Nov;16(11):116009

California Institute of Technology, Bioengineering, Pasadena, California 91125, USA.

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http://dx.doi.org/10.1117/1.3647570DOI Listing
November 2011

Computational analysis of the spatiotemporal coordination of polarized PI3K and Rac1 activities in micro-patterned live cells.

PLoS One 2011 27;6(6):e21293. Epub 2011 Jun 27.

Department of Bioengineering, University of Illinois at Urbana-Champaign, Champaign, Illinois, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021293PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124492PMC
December 2011

Simultaneous visualization of protumorigenic Src and MT1-MMP activities with fluorescence resonance energy transfer.

Cancer Res 2010 Mar 2;70(6):2204-12. Epub 2010 Mar 2.

Department of Bioengineering, Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana-Champaign, Illinois 61801, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840183PMC
March 2010

Rapid activation of Rac GTPase in living cells by force is independent of Src.

PLoS One 2009 Nov 18;4(11):e7886. Epub 2009 Nov 18.

Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007886PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773925PMC
November 2009

Plectin contributes to mechanical properties of living cells.

Am J Physiol Cell Physiol 2009 Apr 25;296(4):C868-77. Epub 2009 Feb 25.

Dept. of Mechanical Science, Univ. of Illinois, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1152/ajpcell.00604.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670656PMC
April 2009

Visualization of Src activity at different compartments of the plasma membrane by FRET imaging.

Chem Biol 2009 Jan;16(1):48-57

Neuroscience Program, Center for Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1016/j.chembiol.2008.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2647969PMC
January 2009

Substrate rigidity regulates Ca2+ oscillation via RhoA pathway in stem cells.

J Cell Physiol 2009 Feb;218(2):285-93

Neuroscience Program, Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana-Champaign, Urbana, Illinois, USA.

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http://dx.doi.org/10.1002/jcp.21598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592496PMC
February 2009

Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors.

Proc Natl Acad Sci U S A 2008 Sep 17;105(38):14353-8. Epub 2008 Sep 17.

Department of Bioengineering, Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana-Champaign, IL 61801, USA.

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http://dx.doi.org/10.1073/pnas.0807537105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567163PMC
September 2008

The spatiotemporal pattern of Src activation at lipid rafts revealed by diffusion-corrected FRET imaging.

PLoS Comput Biol 2008 Jul 25;4(7):e1000127. Epub 2008 Jul 25.

Department of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA.

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http://dx.doi.org/10.1371/journal.pcbi.1000127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2517613PMC
July 2008

Rapid signal transduction in living cells is a unique feature of mechanotransduction.

Proc Natl Acad Sci U S A 2008 May 2;105(18):6626-31. Epub 2008 May 2.

Departments of Mechanical Science and Engineering and Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1073/pnas.0711704105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373315PMC
May 2008

Visualization of polarized membrane type 1 matrix metalloproteinase activity in live cells by fluorescence resonance energy transfer imaging.

J Biol Chem 2008 Jun 25;283(25):17740-8. Epub 2008 Apr 25.

Department of Bioengineering and the Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana-Champaign, Illinois 61801, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M709872200
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http://dx.doi.org/10.1074/jbc.M709872200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427332PMC
June 2008

Critical role of ASK1 in the 6-hydroxydopamine-induced apoptosis in human neuroblastoma SH-SY5Y cells.

J Neurochem 2006 Apr 3;97(1):234-44. Epub 2006 Mar 3.

Institute of Biophysics, Chinese Academy of Science, Graduate School of the Chinese Academy of Sciences, Beijing, China.

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http://dx.doi.org/10.1111/j.1471-4159.2006.03730.xDOI Listing
April 2006