Mingtao Huang

Mingtao Huang

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Mingtao Huang

Mingtao Huang

Publications by authors named "Mingtao Huang"

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20Publications

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Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.

Lancet Respir Med 2019 Jul 17. Epub 2019 Jul 17.

Department of Epidemiology and Biostatistics, International Joint Research Center on Environment and Human Health, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Medicine, Nanjing Medical University, Nanjing, China. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(19)30144-4DOI Listing
July 2019

RNAi expression tuning, microfluidic screening, and genome recombineering for improved protein production in .

Proc Natl Acad Sci U S A 2019 May 18;116(19):9324-9332. Epub 2019 Apr 18.

Department of Biology and Biological Engineering, Chalmers University of Technology, SE41296 Gothenburg, Sweden;

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http://dx.doi.org/10.1073/pnas.1820561116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511059PMC
May 2019

Fine mapping the MHC region identified rs4997052 as a new variant associated with nonobstructive azoospermia in Han Chinese males.

Fertil Steril 2019 01 28;111(1):61-68. Epub 2018 Nov 28.

Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China; Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China; State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2018.08.052DOI Listing
January 2019

Engineering the protein secretory pathway of enables improved protein production.

Proc Natl Acad Sci U S A 2018 11 5;115(47):E11025-E11032. Epub 2018 Nov 5.

Department of Biology and Biological Engineering, Chalmers University of Technology, SE41296 Gothenburg, Sweden;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1809921115
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http://dx.doi.org/10.1073/pnas.1809921115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255153PMC
November 2018

Reprogramming Yeast Metabolism from Alcoholic Fermentation to Lipogenesis.

Cell 2018 09 9;174(6):1549-1558.e14. Epub 2018 Aug 9.

Department of Biology and Biological Engineering, Chalmers University of Technology, Kemivägen 10, 41296 Gothenburg, Sweden; Novo Nordisk Foundation Center for Biosustainability, Chalmers University of Technology, 41296 Gothenburg, Sweden; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800 Kongens Lyngby, Denmark. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183090
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http://dx.doi.org/10.1016/j.cell.2018.07.013DOI Listing
September 2018

Global rewiring of cellular metabolism renders Saccharomyces cerevisiae Crabtree negative.

Nat Commun 2018 08 3;9(1):3059. Epub 2018 Aug 3.

Department of Biology and Biological Engineering, Chalmers University of Technology, SE-41296, Gothenburg, Sweden.

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http://dx.doi.org/10.1038/s41467-018-05409-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076296PMC
August 2018

High-Throughput Microfluidics for the Screening of Yeast Libraries.

Methods Mol Biol 2018 ;1671:307-317

Department of Biology and Biological Engineering, Chalmers University of Technology, SE-41296, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/978-1-4939-7295-1_19DOI Listing
July 2018

Genetically determined height was associated with lung cancer risk in East Asian population.

Cancer Med 2018 May 23. Epub 2018 May 23.

Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1002/cam4.1557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051217PMC
May 2018

Balanced trafficking between the ER and the Golgi apparatus increases protein secretion in yeast.

AMB Express 2018 Mar 12;8(1):37. Epub 2018 Mar 12.

Department of Biology and Biological Engineering, Chalmers University of Technology, 41296, Gothenburg, Sweden.

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http://dx.doi.org/10.1186/s13568-018-0571-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847638PMC
March 2018

Exploring the potential of Saccharomyces cerevisiae for biopharmaceutical protein production.

Curr Opin Biotechnol 2017 12 11;48:77-84. Epub 2017 Apr 11.

Department of Biology and Biological Engineering, Chalmers University of Technology, SE41296 Gothenburg, Sweden; Novo Nordisk Foundation Center for Biosustainability, Chalmers University of Technology, SE41296 Gothenburg, Sweden; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, DK2970 Hørsholm, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.copbio.2017.03.017DOI Listing
December 2017

Transcriptome-wide association study revealed two novel genes associated with nonobstructive azoospermia in a Chinese population.

Fertil Steril 2017 12;108(6):1056-1062.e4

State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, People's Republic of China; Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2017.09.023DOI Listing
December 2017

Genetic association of telomere length with hepatocellular carcinoma risk: A Mendelian randomization analysis.

Cancer Epidemiol 2017 10 7;50(Pt A):39-45. Epub 2017 Aug 7.

Department of Epidemiology and Biostatistics, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center For Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing 211166, China. Electronic address:

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http://dx.doi.org/10.1016/j.canep.2017.07.011DOI Listing
October 2017

Efficient protein production by yeast requires global tuning of metabolism.

Nat Commun 2017 10 25;8(1):1131. Epub 2017 Oct 25.

Department of Biology and Biological Engineering, Chalmers University of Technology, SE41296, Gothenburg, Sweden.

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http://dx.doi.org/10.1038/s41467-017-00999-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656615PMC
October 2017

Fine-mapping the MHC region in Asian populations identified novel variants modifying susceptibility to lung cancer.

Lung Cancer 2017 10 31;112:169-175. Epub 2017 Aug 31.

Department of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 211166, China; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Medicine, Nanjing Medical University, Nanjing 211166, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01695002173048
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http://dx.doi.org/10.1016/j.lungcan.2017.08.016DOI Listing
October 2017

A cis-eQTL genetic variant of the cancer-testis gene CCDC116 is associated with risk of multiple cancers.

Hum Genet 2017 08 26;136(8):987-997. Epub 2017 Jun 26.

State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, 210029, China.

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http://dx.doi.org/10.1007/s00439-017-1827-2DOI Listing
August 2017

Moderate Expression of Increases Protein Secretion by Saccharomyces cerevisiae.

Appl Environ Microbiol 2017 07 30;83(14). Epub 2017 Jun 30.

Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden

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http://dx.doi.org/10.1128/AEM.03400-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494634PMC
July 2017

Modular pathway rewiring of Saccharomyces cerevisiae enables high-level production of L-ornithine.

Nat Commun 2015 Sep 8;6:8224. Epub 2015 Sep 8.

Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg SE-412 96, Sweden.

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http://dx.doi.org/10.1038/ncomms9224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569842PMC
September 2015

Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast.

Proc Natl Acad Sci U S A 2015 Aug 10;112(34):E4689-96. Epub 2015 Aug 10.

Department of Biology and Biological Engineering, Chalmers University of Technology, SE41296 Gothenburg, Sweden; Novo Nordisk Foundation Center for Biosustainability, Chalmers University of Technology, SE41296 Gothenburg, Sweden; Science for Life Laboratory, KTH Royal Institute of Technology, SE17165 Solna, Sweden; Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, DK2970 Hørsholm, Denmark

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http://dx.doi.org/10.1073/pnas.1506460112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553813PMC
August 2015

Improved production of a heterologous amylase in Saccharomyces cerevisiae by inverse metabolic engineering.

Appl Environ Microbiol 2014 Sep 27;80(17):5542-50. Epub 2014 Jun 27.

Novo Nordisk Foundation Center for Biosustainability, Department of Chemical and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Hørsholm, Denmark

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http://aem.asm.org/content/80/17/5542.full.pdf
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http://aem.asm.org/content/early/2014/06/23/AEM.00712-14.ful
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http://aem.asm.org/cgi/doi/10.1128/AEM.00712-14
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http://dx.doi.org/10.1128/AEM.00712-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136093PMC
September 2014

High-throughput screening for industrial enzyme production hosts by droplet microfluidics.

Lab Chip 2014 Feb;14(4):806-13

Division of Proteomics and Nanobiotechnology, Science for Life Laboratory, Royal Institute of Technology (KTH), Sweden.

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http://orbit.dtu.dk/files/87769898/prod11391208532991.joenss
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http://xlink.rsc.org/?DOI=C3LC51202A
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http://dx.doi.org/10.1039/c3lc51202aDOI Listing
February 2014