Publications by authors named "Ming-Chao Zhong"

25Publications

SLAM family receptors control pro-survival effectors in germinal center B cells to promote humoral immunity.

J Exp Med 2021 Mar;218(3)

Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal, Montréal, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20200756DOI Listing
March 2021

[Loss of human ICOSLG results in combined immunodeficiency].

Med Sci (Paris) 2019 Aug-Sep;35(8-9):625-628. Epub 2019 Sep 18.

Le Programme en maladies infectieuses et immunité en santé mondiale, Centre universitaire de santé McGill, Institut de recherche, 1001 Decarie, H4A3J1 Montréal, Québec, Canada. - Laboratoire d'oncologie moléculaire, Institut de recherches cliniques de Montréal, Montréal, Québec, Canada. - Département de médecine, Université McGill, Montréal, Québec, Canada. - Département de médecine, Université de Montréal, Montréal, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1051/medsci/2019126DOI Listing
April 2020

SLAM receptors foster iNKT cell development by reducing TCR signal strength after positive selection.

Nat Immunol 2019 04 4;20(4):447-457. Epub 2019 Mar 4.

Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal, Montréal, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41590-019-0334-0DOI Listing
April 2019

Morpholino-based correction of hypomorphic ZAP70 mutation in an adult with combined immunodeficiency.

J Allergy Clin Immunol 2017 05 17;139(5):1688-1692.e10. Epub 2017 Feb 17.

Infectious Disease Susceptibility Program, McGill University Health Centre (MUHC) and Research Institute-MUHC (RI-MUHC), Montreal, Quebec, Canada; Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal (IRCM), Montreal, Quebec, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2017.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7126384PMC
May 2017

The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors.

Cell Rep 2016 12;17(10):2776-2788

Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal, Montréal, QC H2W 1R7, Canada; Department of Medicine, University of Montréal, Montréal, QC H3C 3J7, Canada; Department of Medicine, McGill University, Montréal, QC H3G 1Y6, Canada. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2016.11.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656005PMC
December 2016

Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1.

J Exp Med 2016 09 29;213(10):2187-207. Epub 2016 Aug 29.

Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal, Montréal, Québec H2W 1R7, Canada Department of Medicine, McGill University, Montréal, Québec H3G 1Y6, Canada Department of Medicine, University of Montréal, Montréal, Québec H3T 1J4, Canada

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20160552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5030809PMC
September 2016

A hematopoietic cell-driven mechanism involving SLAMF6 receptor, SAP adaptors and SHP-1 phosphatase regulates NK cell education.

Nat Immunol 2016 Apr 15;17(4):387-96. Epub 2016 Feb 15.

Laboratory of Molecular Oncology, Institut de recherches cliniques de Montréal (IRCM), Montréal, Québec, Canada.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/ni.3369
Publisher Site
http://dx.doi.org/10.1038/ni.3369DOI Listing
April 2016

Loss of PTPN12 Stimulates Progression of ErbB2-Dependent Breast Cancer by Enhancing Cell Survival, Migration, and Epithelial-to-Mesenchymal Transition.

Mol Cell Biol 2015 Dec 21;35(23):4069-82. Epub 2015 Sep 21.

Laboratory of Molecular Oncology, Clinical Research Institute of Montréal, Montréal, Québec, Canada Department of Medicine, McGill University, Montréal, Québec, Canada Department of Medicine, University of Montréal, Montréal, Québec, Canada

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.00741-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628068PMC
December 2015

Control of dendritic cell migration, T cell-dependent immunity, and autoimmunity by protein tyrosine phosphatase PTPN12 expressed in dendritic cells.

Mol Cell Biol 2014 Mar 23;34(5):888-99. Epub 2013 Dec 23.

Laboratory of Molecular Oncology, Clinical Research Institute of Montréal, Montréal, Québec, Canada.

View Article

Download full-text PDF

Source
http://mcb.asm.org/lookup/doi/10.1128/MCB.01369-13
Publisher Site
http://dx.doi.org/10.1128/MCB.01369-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023833PMC
March 2014

The adaptor molecule signaling lymphocytic activation molecule (SLAM)-associated protein (SAP) is essential in mechanisms involving the Fyn tyrosine kinase for induction and progression of collagen-induced arthritis.

J Biol Chem 2013 Nov 17;288(44):31423-36. Epub 2013 Sep 17.

From the Laboratory of Molecular Oncology, Clinical Research Institute of Montréal, Montréal, Québec H2W 1R7, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M113.473736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814739PMC
November 2013

Critical role of SAP in progression and reactivation but not maintenance of T cell-dependent humoral immunity.

Mol Cell Biol 2013 Mar 14;33(6):1223-32. Epub 2013 Jan 14.

Laboratory of Molecular Oncology, Clinical Research Institute of Montreal, Montreal, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.01591-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3592029PMC
March 2013

Immunology: Csk keeps LYP on a leash.

Nat Chem Biol 2012 Apr 17;8(5):412-3. Epub 2012 Apr 17.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/nchembio.940
Publisher Site
http://dx.doi.org/10.1038/nchembio.940DOI Listing
April 2012

The phosphatase PTP-PEST promotes secondary T cell responses by dephosphorylating the protein tyrosine kinase Pyk2.

Immunity 2010 Aug;33(2):167-80

Laboratory of Molecular Oncology, Clinical Research Institute of Montréal, Montréal, Québec H2W 1R7, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2010.08.001DOI Listing
August 2010

Importance and mechanism of 'switch' function of SAP family adapters.

Immunol Rev 2009 Nov;232(1):229-39

Laboratory of Molecular Oncology, Clinical Research Institute of Montréal, Montréal, Québec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1600-065X.2009.00824.xDOI Listing
November 2009

Essential function for SAP family adaptors in the surveillance of hematopoietic cells by natural killer cells.

Nat Immunol 2009 Sep 2;10(9):973-80. Epub 2009 Aug 2.

Laboratory of Molecular Oncology, Clinical Research Institute of Montréal, Montréal, Québec, Canada.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/ni.1763
Publisher Site
http://dx.doi.org/10.1038/ni.1763DOI Listing
September 2009

Control of T lymphocyte signaling by Ly108, a signaling lymphocytic activation molecule family receptor implicated in autoimmunity.

J Biol Chem 2008 Jul 15;283(28):19255-64. Epub 2008 May 15.

Laboratory of Molecular Oncology, Clinical Research Institute of Montréal, Montréal, Québec H2W 1R7.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M800209200DOI Listing
July 2008

SAP expression in T cells, not in B cells, is required for humoral immunity.

Proc Natl Acad Sci U S A 2008 Jan 22;105(4):1273-8. Epub 2008 Jan 22.

Laboratory of Molecular Oncology, Clinical Research Institute of Montréal, Montréal, QC, Canada.

View Article

Download full-text PDF

Source
http://www.pnas.org/cgi/doi/10.1073/pnas.0710698105
Publisher Site
http://dx.doi.org/10.1073/pnas.0710698105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234128PMC
January 2008

SLAM family receptors and SAP-related adaptors: matters arising.

Trends Immunol 2006 May 3;27(5):228-34. Epub 2006 Apr 3.

Clinical Research Institute of Montreal, Montreal, Quebec, Canada H2W 1R7.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.it.2006.03.003DOI Listing
May 2006