Publications by authors named "Ming Ta Michael Lee"

60Publications

Genome-Wide Association Analysis Across 16,956 Patients Identifies a Novel Genetic Association Between BMP6, NIPAL1, CNGA1 and Spondylosis.

Spine (Phila Pa 1976) 2020 Dec 15;Publish Ahead of Print. Epub 2020 Dec 15.

Genomic Medicine Institute, Geisinger, Danville, PA, USA Genomic Research, Musculoskeletal Institute, Geisinger, Danville, PA, USA Department of Neurosurgery, Geisinger, Danville, PA, USA Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA Institute for Biomedical Informatics, University of Pennsylvania, Philadelphia, PA, United States Geisinger Commonwealth Medical School, Scranton, PA, USA.

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December 2020

PharmVar GeneFocus: CYP2C19.

Clin Pharmacol Ther 2020 Jun 29. Epub 2020 Jun 29.

Division of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy, Kansas City, Missouri, USA.

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June 2020

Copy Number Is Not Associated With Risk of Kidney Failure in a Large Cohort.

Front Genet 2019 30;10:765. Epub 2019 Aug 30.

Genomic Medicine Institute, Geisinger, Danville, PA, United States.

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August 2019

Human-Disease Phenotype Map Derived from PheWAS across 38,682 Individuals.

Am J Hum Genet 2019 01 29;104(1):55-64. Epub 2018 Dec 29.

The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA 16802, USA; Biomedical and Translational Informatics Institute, Geisinger, Danville, PA 17821, USA. Electronic address:

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January 2019

Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals.

Clin Pharmacol Ther 2019 06 17;105(6):1477-1491. Epub 2019 Feb 17.

General Medicine and Hypertension Unit, Department of Medicine, University of Verona, Verona, Italy.

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June 2019

Chromatin accessibility landscape of articular knee cartilage reveals aberrant enhancer regulation in osteoarthritis.

Sci Rep 2018 10 19;8(1):15499. Epub 2018 Oct 19.

Epigenome Technology Exploration Unit, Division of Genomic Technologies, RIKEN Center for Life Science Technologies (CLST), Yokohama, Japan.

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October 2018

Polymorphic analysis of CYP2C9 gene in Vietnamese population.

Mol Biol Rep 2018 Oct 5;45(5):893-900. Epub 2018 Jul 5.

Institute of Genome Research, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay, Hanoi, Vietnam.

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October 2018

Pharmacogenetics of lithium effects on glomerular function in bipolar disorder patients under chronic lithium treatment: a pilot study.

Neurosci Lett 2017 01 5;638:1-4. Epub 2016 Dec 5.

Section of Neurosciences and Clinical Pharmacology, Department of Biomedical Sciences, School of Medicine, University of Cagliari, Cagliari, Italy. Electronic address:

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January 2017

Identification of DNA methylation changes associated with disease progression in subchondral bone with site-matched cartilage in knee osteoarthritis.

Sci Rep 2016 Sep 30;6:34460. Epub 2016 Sep 30.

Laboratory for International Alliance on Genomic Research, Center for Integrative Medical Sciences, RIKEN, Yokohama, Japan.

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September 2016

Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity.

BMC Genomics 2016 Sep 26;17(1):755. Epub 2016 Sep 26.

Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska University Hospital Huddinge C1:68, Karolinska Institutet, SE-141 86, Stockholm, Sweden.

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September 2016

Identification of susceptibility gene associated with female primary Sjögren's syndrome in Han Chinese by genome-wide association study.

Hum Genet 2016 Nov 8;135(11):1287-1294. Epub 2016 Aug 8.

National Center for Genome Medicine, Institute of Biomedical Sciences, Academia Sinica, 128 Sec. 2, Academia Rd. Nankang, Taipei, 11529, Taiwan.

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November 2016

Clinical application of pharmacogenomics: the example of HLA-based drug-induced toxicity.

Public Health Genomics 2014 21;17(5-6):248-55. Epub 2014 Oct 21.

Laboratory for International Alliance on Genomic Research, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.

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June 2015

Revalidation of CoaguChek XS plus system for INR monitoring in Taiwanese patients: effects of clinical and genetic factors.

Biomed J 2014 Nov-Dec;37(6):380-5

Department of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine; School of Medicine, Chang Gung University, Taoyuan, Taiwan, .

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October 2015

Deciphering next-generation pharmacogenomics: an information technology perspective.

Open Biol 2014 Jul;4(7)

Department of Pharmacy, School of Health Sciences, University of Patras, University Campus, Rion, Patras, Greece

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July 2014

Pharmacogenetics of warfarin: challenges and opportunities.

J Hum Genet 2013 Jun 9;58(6):334-8. Epub 2013 May 9.

Laboratory for International Alliance, RIKEN Center for Genomic Medicine, Yokohama, Japan.

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June 2013

Warfarin Pharmacogenetics: New Life for an Old Drug.

Acta Cardiol Sin 2013 May;29(3):235-42

Laboratory for International Alliance, RIKEN Center for Genomic Medicine, Yokohama, Japan; ; 3Institute of Biomedical Sciences, Academia Sinica, Taipei; ; Graduate Institute of Chinese Medical Science, China Medical University, Taichung, Taiwan.

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May 2013

Pharmacogenomics of adverse drug reactions: implementing personalized medicine.

Hum Mol Genet 2012 Oct 19;21(R1):R58-65. Epub 2012 Aug 19.

Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan.

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October 2012

Pharmacogenetics of toxic epidermal necrolysis.

Expert Opin Pharmacother 2010 Sep;11(13):2153-62

Institute of Biomedical Sciences, Academia Sinica, 128 Academia Road, Section 2, Nankang, 11529 Taipei, Taiwan.

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September 2010

VKORC1 haplotypes in five East-Asian populations and Indians.

Pharmacogenomics 2009 Oct;10(10):1609-16

Institute of Biomedical Sciences, Academia Sinica, 128 Academia Road, Section 2, NanKang, Taipei, Taiwan.

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October 2009

A large kindred of early-onset osteoarthritis of the knee and hip: excluding the link to COL2A1 gene.

Rheumatology (Oxford) 2009 Apr 17;48(4):371-4. Epub 2009 Feb 17.

Institute of Clinical Medicine, National Yang-Ming University, Academia Sinica, Taipei, Taiwan.

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April 2009