Publications



A therapeutic benefit of daptomycin against glycopeptide-resistant gram-positive cocci bloodstream infections under neutropenia.
J Infect Chemother 2017 Jul 22. Epub 2017 Jul 22.
Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan; Department of Cell Therapy and Transplantation Medicine, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. Electronic address:


Extranodal NK/T cell lymphoma in a living donor liver transplant recipient.
Ann Hematol 2017 Jun 9;96(6):1051-1052. Epub 2017 Mar 9.
Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.




Development of the Japanese Version of the Psychosocial Assessment of Candidates for Transplantation in Allogeneic Hematopoietic Stem Cell Transplantation.
Psychosomatics 2017 May - Jun;58(3):292-298. Epub 2017 Jan 19.
Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. Electronic address:



Allogeneic Hematopoietic Cell Transplantation for Leukemic Transformation Preceded by Philadelphia Chromosome-Negative Myeloproliferative Neoplasms: A Nationwide Survey by the Adult Acute Myeloid Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation.
Biol Blood Marrow Transplant 2016 Dec 22;22(12):2208-2213. Epub 2016 Sep 22.
Adult AML Working Group, The Japan Society for Hematopoietic Cell Transplantation, Aichi, Japan; Division of Clinical Oncology and Hematology, Jikei University School of Medicine, Tokyo, Japan.

Haploidentical and Matched Sibling Donor Hematopoietic Cell Transplantation for Patients with HLA-Homozygous Haplotypes.
Biol Blood Marrow Transplant 2016 Nov 1;22(11):2031-2037. Epub 2016 Aug 1.
Division of Hematology, Saitama Medical Center, Jichi Medical University, Saitama, Japan; Division of Hematology, Department of Medicine, Jichi Medical University, Tochigi, Japan. Electronic address:


Incidentally-detected t(9;22)(q34;q11)/BCR-ABL1- positive clone developing into chronic phase chronic myeloid leukaemia after four years of dormancy.
Br J Haematol 2016 Sep 12;174(5):815-7. Epub 2015 Nov 12.
Department of Haematology and Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Cytoprotective autophagy maintains leukemia-initiating cells in murine myeloid leukemia.
Blood 2016 Sep 1;128(12):1614-24. Epub 2016 Aug 1.
Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Department of Cell Therapy and Transplantation, The University of Tokyo Hospital, Tokyo, Japan.



Splenic irradiation provides transient palliation for symptomatic splenomegaly associated with primary myelofibrosis: a report on 14 patients.
Int J Hematol 2016 Apr 20;103(4):423-8. Epub 2016 Jan 20.
Department of Gastroenterology and Hematology, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.

A nationwide survey of co-occurrence of malignant lymphomas and myelodysplastic syndromes/myeloproliferative neoplasms.
Ann Hematol 2016 Apr 19;95(5):829-30. Epub 2016 Feb 19.
Department of Hematology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.

DNMT3A R882 mutants interact with polycomb proteins to block haematopoietic stem and leukaemic cell differentiation.
Nat Commun 2016 Mar 24;7:10924. Epub 2016 Mar 24.
Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, bunkyo-ku, Tokyo 113-8655, Japan.



miR-133 regulates Evi1 expression in AML cells as a potential therapeutic target.
Sci Rep 2016 Jan 12;6:19204. Epub 2016 Jan 12.
Department of Hematological Malignancy, Institute of Medical Science, Tokai University, 143 Shimokasuya, Isehara, Kanagawa 259-1193 Japan.



Targeted gene correction of RUNX1 in induced pluripotent stem cells derived from familial platelet disorder with propensity to myeloid malignancy restores normal megakaryopoiesis.
Exp Hematol 2015 Oct 11;43(10):849-57. Epub 2015 Jun 11.
Department of Hematology & Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Tokyo, Japan. Electronic address:


Adiponectin regulates psoriasiform skin inflammation by suppressing IL-17 production from γδ-T cells.
Nat Commun 2015 Jul 15;6:7687. Epub 2015 Jul 15.
Department of Dermatology, University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.


Paraneoplastic pemphigus occurring after bendamustine and rituximab therapy for relapsed follicular lymphoma.
Ann Hematol 2015 Apr 10;94(4):683-5. Epub 2014 Sep 10.
Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Bacterial c-di-GMP affects hematopoietic stem/progenitors and their niches through STING.
Cell Rep 2015 Apr 2;11(1):71-84. Epub 2015 Apr 2.
Department of Stem Cell Biology, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan; Department of Cell Differentiation, The Sakaguchi Laboratory of Developmental Biology, Keio University School of Medicine, Tokyo 160-8582, Japan; Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Kawaguchi, Saitama 332-0012, Japan. Electronic address:

Effects of universal vs bedside leukoreductions on the alloimmunization to platelets and the platelet transfusion refractoriness.
Transfus Apher Sci 2015 Feb 11;52(1):112-21. Epub 2014 Nov 11.
Department of Transfusion Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPα.
Carcinogenesis 2014 Nov 19;35(11):2404-14. Epub 2014 Jun 19.
Department of Gastroenterology, Department of Hematology and Oncology and Department of Pathology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan, Division of Clinical Genome Research, The Institute of Medical Science, University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan, Hepato-Biliary-Pancreatic Surgery Division, Artificial Organ and Transplantation Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo , Bunkyo-ku, Tokyo, 113-8655, Japan and Yamanashi Prefectural Central Hospital, 1-1-1 Fujimi-cho, Kofu-shi, Yamanashi-Prefecture 400-8506, Japan.


Autoimmune neutropenia preceding Helicobacter pylori-negative MALT lymphoma with nodal dissemination.
Int J Clin Exp Pathol 2014 15;7(9):6386-90. Epub 2014 Aug 15.
Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan ; Department of Cell Therapy and Transplantation Medicine, The University of Tokyo Hospital Tokyo, Japan.

Generation of induced pluripotent stem cells derived from primary and secondary myelofibrosis patient samples.
Exp Hematol 2014 Sep 20;42(9):816-25. Epub 2014 May 20.
Department of Hematology and Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; CREST, Japan Science and Technology Agency (JST), Tokyo, Japan. Electronic address:


Recurrent CDC25C mutations drive malignant transformation in FPD/AML.
Nat Commun 2014 Aug 27;5:4770. Epub 2014 Aug 27.
Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

Pulmonary mucormycosis with embolism: two autopsied cases of acute myeloid leukemia.
Int J Clin Exp Pathol 2014 15;7(6):3449-53. Epub 2014 May 15.
Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo Japan ; Department of Cell Therapy and Transplantation Medicine, The University of Tokyo Hospital Japan.


The role of alloantibodies against human platelet antigen-15 in multiply platelet transfused patients.
Transfusion 2014 Apr 22;54(4):1093-9. Epub 2013 Oct 22.
Department of Transfusion Medicine, The University of Tokyo, Giessen, Germany; Analytical Laboratory Chemistry, Graduate School of Health Care Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice.
Cell Metab 2014 Apr;19(4):593-604
Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Smilow Center for Translational Research, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Smilow Center for Translational Research, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA. Electronic address:

Serial profile of vitamins and trace elements during the acute phase of allogeneic stem cell transplantation.
Biol Blood Marrow Transplant 2014 Mar 11;20(3):430-4. Epub 2013 Dec 11.
Department of Hematology & Oncology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan; Department of Cell Therapy and Transplantation Medicine, University of Tokyo Hospital, Tokyo, Japan. Electronic address:

Transformation of follicular lymphoma in the retroperitoneal muscles demonstrated by CT-guided needle biopsy of FDG-avid lesions; case series.
Int J Clin Exp Pathol 2014 15;7(1):402-6. Epub 2013 Dec 15.
Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo Japan ; Department of Cell Therapy and Transplantation Medicine, The University of Tokyo Hospital Japan.

Mutational Landscape and Antiproliferative Functions of ELF Transcription Factors in Human Cancer.
Cancer Res 2016 04 26;76(7):1814-24. Epub 2016 Feb 26.
Department of Cellular Signaling, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. Strategic Basic Research Program, Japan Science and Technology Agency, Saitama, Japan.

OF