Milos D Ikonomovic

Milos D Ikonomovic

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Milos D Ikonomovic

Milos D Ikonomovic

Publications by authors named "Milos D Ikonomovic"

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Nerve Growth Factor Pathobiology During the Progression of Alzheimer's Disease.

Front Neurosci 2019 1;13:533. Epub 2019 Jul 1.

Department of Neurology and Department of Psychiatry, Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, University of Pittsburgh, Pittsburgh, PA, United States.

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http://dx.doi.org/10.3389/fnins.2019.00533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613497PMC
July 2019

Neuropathological correlates of amyloid PET imaging in Down syndrome.

Dev Neurobiol 2019 07 17;79(7):750-766. Epub 2019 Aug 17.

Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/dneu.22713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892598PMC
July 2019

Novel therapies for combating chronic neuropathological sequelae of TBI.

Neuropharmacology 2019 02 20;145(Pt B):160-176. Epub 2018 Jun 20.

Geriatric Research Education and Clinical Center, Pittsburgh VA Healthcare System, Pittsburgh, PA, USA; Department of Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.neuropharm.2018.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513317PMC
February 2019

Impact of partial volume correction on the regional correspondence between in vivo [C-11]PiB PET and postmortem measures of Aβ load.

Neuroimage Clin 2018 4;19:182-189. Epub 2018 Apr 4.

Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA; Geriatric Research Education and Clinical Center, Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.nicl.2018.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050460PMC
January 2019

Acute and chronic effects of single dose memantine after controlled cortical impact injury in adult rats.

Restor Neurol Neurosci 2019 ;37(3):245-263

Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, University of Pittsburgh, Pittsburgh PA, USA.

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http://dx.doi.org/10.3233/RNN-190909DOI Listing
January 2019

Synaptic Proteome Compensation and Resilience to Psychosis in Alzheimer's Disease.

Am J Psychiatry 2018 10 19;175(10):999-1009. Epub 2018 Jul 19.

From the Departments of Psychiatry, Cell Biology, Neurology, and Pathology, University of Pittsburgh School of Medicine, Pittsburgh; the Department of Biostatistics, University of Pittsburgh School of Public Health, Pittsburgh; the Departments of Physiology and Psychiatry and Behavioral Sciences, Northwestern University, Feinberg School of Medicine, Chicago; the Geriatric Research, Education, and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh; and the Mental Illness Research, Education, and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh.

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http://dx.doi.org/10.1176/appi.ajp.2018.17080858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167138PMC
October 2018

Infrequent false positive [F]flutemetamol PET signal is resolved by combined histological assessment of neuritic and diffuse plaques.

Alzheimers Res Ther 2018 06 23;10(1):60. Epub 2018 Jun 23.

Director of Neurology and the Memory and Aging Program at Butler Hospital in Providence, Providence, RI, USA.

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http://dx.doi.org/10.1186/s13195-018-0387-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015459PMC
June 2018

Progression of tau pathology within cholinergic nucleus basalis neurons in chronic traumatic encephalopathy: A chronic effects of neurotrauma consortium study.

Brain Inj 2016 ;30(12):1399-1413

f VA Boston HealthCare System, Alzheimer Disease Center and CTE Program and Departments of Neurology and Pathology , Boston University School of Medicine , Boston , MA , USA.

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http://dx.doi.org/10.1080/02699052.2016.1219058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348250PMC
January 2018

Small-molecule PET Tracers for Imaging Proteinopathies.

Semin Nucl Med 2017 09 13;47(5):553-575. Epub 2017 Jul 13.

Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1053/j.semnuclmed.2017.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657567PMC
September 2017

Loss of precuneus dendritic spines immunopositive for spinophilin is related to cognitive impairment in early Alzheimer's disease.

Neurobiol Aging 2017 07 4;55:159-166. Epub 2017 Feb 4.

Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA; Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.01.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440205PMC
July 2017

Kalirin reduction rescues psychosis-associated behavioral deficits in APPswe/PSEN1dE9 transgenic mice.

Neurobiol Aging 2017 06 16;54:59-70. Epub 2017 Feb 16.

Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Mental Illness Research, Education, and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502748PMC
June 2017

Disordered APP metabolism and neurovasculature in trauma and aging: Combined risks for chronic neurodegenerative disorders.

Ageing Res Rev 2017 Mar 6;34:51-63. Epub 2016 Nov 6.

Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh PA 15213, USA; Department of Neurology, University Of Pittsburgh School of Medicine, Pittsburgh PA 15213, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15681637163020
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http://dx.doi.org/10.1016/j.arr.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315701PMC
March 2017

Biomarkers for the Early Detection and Progression of Alzheimer's Disease.

Neurotherapeutics 2017 01;14(1):35-53

Department of Neurobiology and Neurology, Barrow Neurological Institute, Phoenix, AZ, USA.

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http://dx.doi.org/10.1007/s13311-016-0481-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233625PMC
January 2017

Molecular and cellular pathophysiology of preclinical Alzheimer's disease.

Behav Brain Res 2016 09 13;311:54-69. Epub 2016 May 13.

Center for Dementia Research, Nathan Kline Institute, Department of Psychiatry, Department of Neuroscience & Physiology, New York University Langone Medical Center, Orangeburg, NY, United States.

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http://dx.doi.org/10.1016/j.bbr.2016.05.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931948PMC
September 2016

Tenascin-C Is Associated with Cored Amyloid-β Plaques in Alzheimer Disease and Pathology Burdened Cognitively Normal Elderly.

J Neuropathol Exp Neurol 2016 09 21;75(9):868-76. Epub 2016 Jul 21.

From the Departments of Neurology (ZM, EEA, WEK, MDI)Department of Neurobiology (WH)Department of Psychiatry (WEK, MDI)Department of Radiology, University of Pittsburgh (CAM)Department of Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System (ZM, EEA, MDI)Department of Neurobiology, Barrow Neurological Institute, Pittsburgh, PA, USA (EJM)

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http://dx.doi.org/10.1093/jnen/nlw062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909866PMC
September 2016

[F-18]AV-1451 positron emission tomography retention in choroid plexus: More than "off-target" binding.

Ann Neurol 2016 08 7;80(2):307-8. Epub 2016 Jul 7.

Departments of Neurology, University of Pittsburgh, VA Pittsburgh HS, Pittsburgh, PA.

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http://dx.doi.org/10.1002/ana.24706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982815PMC
August 2016

Expression of ATP-Binding Cassette Transporters B1 and C1 after Severe Traumatic Brain Injury in Humans.

J Neurotrauma 2016 Jan 17;33(2):226-31. Epub 2015 Jun 17.

1 Department of Critical Care Medicine, University of Pittsburgh School of Medicine , the Safar Center for Resuscitation Research and the Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1089/neu.2015.3879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722575PMC
January 2016

Resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal Alzheimer's disease.

Biol Psychiatry 2015 Apr 11;77(8):693-703. Epub 2014 Jan 11.

Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2013.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096429PMC
April 2015

Hippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with aβ and tau pathology.

J Neuropathol Exp Neurol 2015 Apr;74(4):345-58

From the Department Neurological Science, Rush University Medical Center, Chicago, Illinois (SEP, EJM); Alzheimer's Disease Research Laboratory, Barrow Neurological Institute, Phoenix, Arizona (BH, MN, EJM); Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida (JW); Center for Dementia Research, Nathan Kline Institute, Orangeburg, New York (SDG); and Departments of Psychiatry, Physiology and Neuroscience, NYU Langone Medical Center, New York (SDG), New York; and Departments of Neurology and Psychiatry, University of Pittsburgh and Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania (MDI).

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http://dx.doi.org/10.1097/NEN.0000000000000179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366294PMC
April 2015

Detection of PHLPP1α/β in human and mouse brain by different anti-PHLPP1 antibodies.

Sci Rep 2015 Apr 1;5:9377. Epub 2015 Apr 1.

University of Pittsburgh School of Medicine, Department of Critical Care Medicine, Safar Center for Resuscitation Research, 200 Hill Building, 3434 Fifth Avenue.

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http://dx.doi.org/10.1038/srep09377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649889PMC
April 2015

Cortical pyroglutamate amyloid-β levels and cognitive decline in Alzheimer's disease.

Neurobiol Aging 2015 Jan 24;36(1):12-9. Epub 2014 Jun 24.

Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA; Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268150PMC
January 2015

Hyperphosphorylated tau is elevated in Alzheimer's disease with psychosis.

J Alzheimers Dis 2014 ;39(4):759-73

Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA VISN 4 Mental Illness Research, Education and Clinical Center, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.3233/JAD-131166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034758PMC
October 2014

Chronic traumatic encephalopathy: clinical-biomarker correlations and current concepts in pathogenesis.

Mol Neurodegener 2014 Sep 17;9:37. Epub 2014 Sep 17.

Departments of Neurology, Icahn School of Medicine at Mount Sinai, One Gustave L Levy Place, New York, NY 10029, USA.

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http://dx.doi.org/10.1186/1750-1326-9-37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249716PMC
September 2014

Synapse stability in the precuneus early in the progression of Alzheimer's disease.

J Alzheimers Dis 2013 ;35(3):599-609

Sanders Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA.

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http://dx.doi.org/10.3233/JAD-122353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000262PMC
October 2013

Dendritic spine density, morphology, and fibrillar actin content surrounding amyloid-β plaques in a mouse model of amyloid-β deposition.

J Neuropathol Exp Neurol 2013 Aug;72(8):791-800

Translational Neuroscience Program, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1097/NEN.0b013e31829ecc89DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763821PMC
August 2013

Cerebral blood flow changes after brain injury in human amyloid-beta knock-in mice.

J Cereb Blood Flow Metab 2013 Jun 27;33(6):826-33. Epub 2013 Feb 27.

Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1038/jcbfm.2013.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677107PMC
June 2013

Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers.

Nat Rev Neurol 2013 Apr;9(4):192-200

Office of the Dean and Department of Neurology, University of Virginia School of Medicine, P. O. Box 800793, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1038/nrneurol.2013.36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006940PMC
April 2013

Using Pittsburgh Compound B for in vivo PET imaging of fibrillar amyloid-beta.

Adv Pharmacol 2012 ;64:27-81

Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/B978-0-12-394816-8.00002-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3542972PMC
March 2013

Mild cognitive impairment: pathology and mechanisms.

Acta Neuropathol 2012 Jan 19;123(1):13-30. Epub 2011 Nov 19.

Department of Neurological Sciences, Rush University Medical Center, 1735 West Harrison St., Suite 300, Chicago, IL 60612, USA.

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http://link.springer.com/content/pdf/10.1007/s00401-011-0884
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http://link.springer.com/10.1007/s00401-011-0884-1
Publisher Site
http://dx.doi.org/10.1007/s00401-011-0884-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282485PMC
January 2012

An immunohistochemical study of the serotonin 1A receptor in the hippocampus of subjects with Alzheimer's disease.

Neuropathology 2011 Oct 27;31(5):503-9. Epub 2011 Jan 27.

Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan.

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http://dx.doi.org/10.1111/j.1440-1789.2010.01193.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112246PMC
October 2011

Heart and brain tissue banks for research on co-occurring cardiovascular and neurological/psychiatric disorders.

Cardiovasc Psychiatry Neurol 2009 15;2009:427840. Epub 2009 Apr 15.

Departments of Neurology and Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1155/2009/427840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790182PMC
July 2011

Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice.

Neurobiol Dis 2011 Feb 16;41(2):338-52. Epub 2010 Oct 16.

Department of Neurological Sciences, Rush University Medical Center, 1735 West Harrison Street, suite 300, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1016/j.nbd.2010.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014453PMC
February 2011

Traumatic brain injury: football, warfare, and long-term effects.

Minn Med 2010 Dec;93(12):46-7

University of Virginia School of Medicine, Charlottesville, USA.

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December 2010

Traumatic brain injury--football, warfare, and long-term effects.

N Engl J Med 2010 Sep 22;363(14):1293-6. Epub 2010 Sep 22.

Office of the Dean and Department of Neurology, University of Virginia School of Medicine, Charlottesville, USA.

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http://dx.doi.org/10.1056/NEJMp1007051DOI Listing
September 2010

Simvastatin therapy prevents brain trauma-induced increases in beta-amyloid peptide levels.

Ann Neurol 2009 Sep;66(3):407-14

Department of Neurology, Brain Trauma Research Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1002/ana.21731DOI Listing
September 2009

Increased 5-lipoxygenase immunoreactivity in the hippocampus of patients with Alzheimer's disease.

J Histochem Cytochem 2008 Dec 4;56(12):1065-73. Epub 2008 Aug 4.

Department of Neurology, University of Pittsburgh School of Medicine, BSTWR S-521, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1369/jhc.2008.951855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583907PMC
December 2008

Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease.

Arch Neurol 2007 Dec;64(12):1771-6

Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1001/archneur.64.12.1771DOI Listing
December 2007

Cholinergic forebrain degeneration in the APPswe/PS1DeltaE9 transgenic mouse.

Neurobiol Dis 2007 Oct 27;28(1):3-15. Epub 2007 Jun 27.

Department of Neurological Sciences, Alla V. and Solomon Jesmer Chair in Aging, Rush University Medical Center, 1735 W. Harrison Street, Suite 300, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1016/j.nbd.2007.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2245889PMC
October 2007

Superior frontal cortex cholinergic axon density in mild cognitive impairment and early Alzheimer disease.

Arch Neurol 2007 Sep;64(9):1312-7

Department of Neurology, University of Pittsburgh School of Medicine, 341 Fifth Ave, Ste 811, Pittsburgh, PA 15213, USA.

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/arc
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http://dx.doi.org/10.1001/archneur.64.9.1312DOI Listing
September 2007

Association of increased cortical soluble abeta42 levels with diffuse plaques after severe brain injury in humans.

Arch Neurol 2007 Apr;64(4):541-4

Department of Neurology, University of Pittsburgh, 3471 Fifth Ave, Suite 811, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1001/archneur.64.4.541DOI Listing
April 2007

X-34 labeling of abnormal protein aggregates during the progression of Alzheimer's disease.

Methods Enzymol 2006 ;412:123-44

Department of Neurology and Psychiatry, University of Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1016/S0076-6879(06)12009-1DOI Listing
November 2006

Galanin fiber hypertrophy within the cholinergic nucleus basalis during the progression of Alzheimer's disease.

Dement Geriatr Cogn Disord 2006 12;21(4):205-14. Epub 2006 Jan 12.

Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1159/000090906DOI Listing
September 2006

Increased phosphorylation of protein kinase B and related substrates after traumatic brain injury in humans and rats.

J Cereb Blood Flow Metab 2006 Jul 19;26(7):915-26. Epub 2005 Oct 19.

Department of Critical Care Medicine, The Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennyslvania 15260, USA.

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http://dx.doi.org/10.1038/sj.jcbfm.9600238DOI Listing
July 2006

Caspase inhibition therapy abolishes brain trauma-induced increases in Abeta peptide: implications for clinical outcome.

Exp Neurol 2006 Feb 21;197(2):437-50. Epub 2005 Nov 21.

Department of Neurology, University of Pittsburgh School of Medicine, 3471 Fifth Avenue, Suite 811, 15213, USA.

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http://dx.doi.org/10.1016/j.expneurol.2005.10.011DOI Listing
February 2006

Apolipoprotein D is a component of compact but not diffuse amyloid-beta plaques in Alzheimer's disease temporal cortex.

Neurobiol Dis 2005 Nov;20(2):574-82

Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/j.nbd.2005.04.012DOI Listing
November 2005

Immunohistochemical study of the hnRNP A2 and B1 in the hippocampal formations of brains with Alzheimer's disease.

Neurosci Lett 2005 Sep;386(2):111-5

Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba City, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.1016/j.neulet.2005.05.070DOI Listing
September 2005

Changes in hippocampal GABABR1 subunit expression in Alzheimer's patients: association with Braak staging.

Acta Neuropathol 2005 May 10;109(5):467-74. Epub 2005 Mar 10.

Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennodai, 305-8575, Tsukuba city, Ibaraki, Japan.

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http://dx.doi.org/10.1007/s00401-005-0985-9DOI Listing
May 2005

Reduction of choline acetyltransferase activity in primary visual cortex in mild to moderate Alzheimer's disease.

Arch Neurol 2005 Mar;62(3):425-30

Department of Neurology and the Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA 25213, USA.

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http://dx.doi.org/10.1001/archneur.62.3.425DOI Listing
March 2005

Immunohistochemical study of hnRNP B1 in the postmortem temporal cortices of patients with Alzheimer's disease.

Neurosci Res 2004 Dec;50(4):481-4

Department of Psychiatry, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba city, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.1016/j.neures.2004.08.013DOI Listing
December 2004

Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury.

Exp Neurol 2004 Nov;190(1):192-203

Department of Neurology, University of Pittsburgh School of Medicine, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/j.expneurol.2004.06.011DOI Listing
November 2004

Effects of post-injury hypothermia and nerve growth factor infusion on antioxidant enzyme activity in the rat: implications for clinical therapies.

J Neurochem 2004 Aug;90(4):998-1004

Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2004.02575.xDOI Listing
August 2004

Time course analysis of hippocampal nerve growth factor and antioxidant enzyme activity following lateral controlled cortical impact brain injury in the rat.

J Neurotrauma 2004 May;21(5):491-500

Department of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1089/089771504774129838DOI Listing
May 2004

Biochemical and molecular studies of NMDA receptor subunits NR1/2A/2B in hippocampal subregions throughout progression of Alzheimer's disease pathology.

Neurobiol Dis 2004 Feb;15(1):80-92

Laboratory of Neuronal Vulnerability and Aging, The Lankenau Institute for Medical Research, Jefferson Health System, Wynnewood, PA, USA.

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http://dx.doi.org/10.1016/j.nbd.2003.09.016DOI Listing
February 2004

Human cholinergic basal forebrain: chemoanatomy and neurologic dysfunction.

J Chem Neuroanat 2003 Dec;26(4):233-42

Department of Neurological Sciences and Alzheimer's Disease Center, Rush Presbyterian-St. Luke's Medical Center, Tech 2000, 2242 West Harrison St., Suite 200, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1016/s0891-0618(03)00068-1DOI Listing
December 2003

Alterations in hippocampal voltage-gated calcium channel alpha 1 subunit expression patterns after kainate-induced status epilepticus in aging rats.

Epilepsy Res 2003 Nov;57(1):15-32

Department of Neurology, Allegheny-Singer Research Institute, Allegheny General Hospital, 940 South Tower, 320 E North Avenue, Pittsburgh, PA 15212-4772, USA.

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http://dx.doi.org/10.1016/j.eplepsyres.2003.10.007DOI Listing
November 2003

Plasticity of glutamate and GABAA receptors in the hippocampus of patients with Alzheimer's disease.

Cell Mol Neurobiol 2003 Oct;23(4-5):491-505

Laboratory of Neuronal Vulnerability and Aging, The Lankenau Institute for Medical Research, Jefferson Health System, Wynnewood, Pennsylvania, USA.

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http://dx.doi.org/10.1023/a:1025063811290DOI Listing
October 2003

Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease.

Arch Neurol 2003 Aug;60(8):1143-8

Department of Neurological Sciences, Rush Presbyterian-St Luke's Medical Center, 2242 W. Harrison Street, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1001/archneur.60.8.1143DOI Listing
August 2003

The binding of 2-(4'-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component.

J Neurosci 2003 Mar;23(6):2086-92

Laboratory of Molecular Neuropharmacology, Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6741999PMC
March 2003

Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: correlation with Alzheimer's neuropathology.

J Alzheimers Dis 2003 Feb;5(1):39-48

Department of Neurology, University of Pittsburgh School of Medicine, PA 15213, USA.

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http://dx.doi.org/10.3233/jad-2003-5106DOI Listing
February 2003

Changes in expression of amyloid precursor protein and interleukin-1beta after experimental traumatic brain injury in rats.

J Neurotrauma 2002 Dec;19(12):1555-67

Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1089/089771502762300229DOI Listing
December 2002

Distribution of plasma alpha 1-antichymotrypsin levels in Alzheimer disease patients and controls and their genetic controls.

Neurobiol Aging 2002 May-Jun;23(3):377-82

Department of Human Genetics, Graduate School of Public Health, 130 DeSoto Street, University of Pittsburgh, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1016/s0197-4580(01)00322-0DOI Listing
June 2002