Milan Jirsa

Milan Jirsa

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Milan Jirsa

Milan Jirsa

Publications by authors named "Milan Jirsa"

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IL28B rs12979860 T allele protects against CMV disease in liver transplant recipients in the post-prophylaxis and late period.

Transpl Infect Dis 2019 Aug 18;21(4):e13124. Epub 2019 Jun 18.

Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

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http://dx.doi.org/10.1111/tid.13124DOI Listing
August 2019

DONOR PNPLA3 AND TM6SF2 VARIANT ALLELES CONFER ADDITIVE RISKS FOR GRAFT STEATOSIS AFTER LIVER TRANSPLANTATION.

Transplantation 2019 Jul 26. Epub 2019 Jul 26.

Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

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http://dx.doi.org/10.1097/TP.0000000000002876DOI Listing
July 2019

Non-Thermal Plasma, as a New Physicochemical Source, to Induce Redox Imbalance and Subsequent Cell Death in Liver Cancer Cell Lines.

Cell Physiol Biochem 2019 18;52(1):119-140. Epub 2019 Feb 18.

Institute of Physics of the Czech Academy of Sciences, Prague, Czech Republic.

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http://dx.doi.org/10.33594/000000009DOI Listing
March 2019

New Insights in Genetic Cholestasis: From Molecular Mechanisms to Clinical Implications.

Can J Gastroenterol Hepatol 2018 26;2018:2313675. Epub 2018 Jul 26.

Department of Gastroenterology, Hepatology, Nutritional Disorders and Pediatrics, The Children's Memorial Health Institute (CMHI), Warsaw 04-730, Poland.

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http://dx.doi.org/10.1155/2018/2313675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6083523PMC
February 2019

Dubin-Johnson syndrome in Tunisia: Spectrum of a rare disease.

Presse Med 2019 Jan 10;48(1 Pt 1):81-82. Epub 2018 Dec 10.

Laboratory of Experimental Hepatology, Experimental Medicine Centre, Institute for Clinical and Experimental Medicine, 14021 Prague 4, Czech Republic.

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http://dx.doi.org/10.1016/j.lpm.2018.09.020DOI Listing
January 2019

Targeting the mTOR Signaling Pathway Utilizing Nanoparticles: A Critical Overview.

Cancers (Basel) 2019 Jan 11;11(1). Epub 2019 Jan 11.

Institute of Physics of the Czech Academy of Sciences, Prague, 18221, Czech Republic.

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http://www.mdpi.com/2072-6694/11/1/82
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http://dx.doi.org/10.3390/cancers11010082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6356373PMC
January 2019

Variable X-chromosome inactivation and enlargement of pericentral glutamine synthetase zones in the liver of heterozygous females with OTC deficiency.

Virchows Arch 2018 Jun 6;472(6):1029-1039. Epub 2018 Apr 6.

Research Unit for Rare Diseases, Department of Pediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University and General University Hospital in Prague, Ke Karlovu 2, 128 08, Prague 2, Czech Republic.

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http://dx.doi.org/10.1007/s00428-018-2345-xDOI Listing
June 2018

Donor PNPLA3 rs738409 genotype is a risk factor for graft steatosis. A post-transplant biopsy-based study.

Dig Liver Dis 2018 May 9;50(5):490-495. Epub 2018 Jan 9.

Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.dld.2017.12.030DOI Listing
May 2018

Manipulating the mitochondria activity in human hepatic cell line Huh7 by low-power laser irradiation.

Biomed Opt Express 2018 Mar 21;9(3):1283-1300. Epub 2018 Feb 21.

Institute of Physics of the Czech Academy of Sciences, Prague, 18221, Czech Republic.

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http://dx.doi.org/10.1364/BOE.9.001283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846531PMC
March 2018

Cytotoxic bilirubin metabolites overlooked so far.

Authors:
Milan Jirsa

J Hepatol 2017 08 8;67(2):214-215. Epub 2017 May 8.

Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.04.025DOI Listing
August 2017

Chemically different non-thermal plasmas target distinct cell death pathways.

Sci Rep 2017 04 4;7(1):600. Epub 2017 Apr 4.

Institute of Physics of the Academy of Sciences of the Czech Republic, Prague, 18221, Czech Republic.

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http://dx.doi.org/10.1038/s41598-017-00689-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428849PMC
April 2017

Modulation of collective cell behaviour by geometrical constraints.

Integr Biol (Camb) 2016 11;8(11):1099-1110

Institute of Physics of the Academy of Sciences of the Czech Republic, Prague, 18221, Czech Republic.

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http://dx.doi.org/10.1039/c6ib00125dDOI Listing
November 2016

HGSNAT has a TATA-less promoter with multiple starts of transcription.

Gene 2016 Oct 22;592(1):36-42. Epub 2016 Jul 22.

Institute of Inherited Metabolic Disorders, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Ke Karlovu 2, Prague 120 08, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2016.07.051DOI Listing
October 2016

Rare variants in known and novel candidate genes predisposing to statin-associated myopathy.

Pharmacogenomics 2016 08 14;17(13):1405-14. Epub 2016 Jun 14.

Institute of Inherited Metabolic Diseases, First Medical Faculty, Charles University, Prague, Czech Republic.

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http://dx.doi.org/10.2217/pgs-2016-0071DOI Listing
August 2016

Alagille Syndrome Mimicking Biliary Atresia in Early Infancy.

PLoS One 2015 30;10(11):e0143939. Epub 2015 Nov 30.

Department of Paediatrics, 2nd Faculty of Medicine, Charles University in Prague and Motol University Hospital, Prague, Czech Republic.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0143939PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664419PMC
July 2016

Prevalence and risk factors of steatosis after liver transplantation and patient outcomes.

Liver Transpl 2016 05 5;22(5):644-55. Epub 2016 Apr 5.

Transplant Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

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http://dx.doi.org/10.1002/lt.24393DOI Listing
May 2016

Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis.

Int J Clin Exp Pathol 2015 1;8(5):5252-62. Epub 2015 May 1.

Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine 14021 Prague 4, Czech Republic.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503098PMC
April 2016

USP18 downregulation in peripheral blood mononuclear cells predicts nonresponse to interferon-based triple therapy in patients with chronic hepatitis C, genotype 1: a pilot study.

Ther Clin Risk Manag 2015 17;11:1853-61. Epub 2015 Dec 17.

Department of Hepatogastroenterology, Resuscitation and Intensive Care, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

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http://dx.doi.org/10.2147/TCRM.S94010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687952PMC
December 2015

Radionuclide cholescintigraphy in genetically confirmed Rotor syndrome.

Pediatr Int 2015 Oct;57(5):981-5

Faculty Hospital and Faculty of Medicine, Ostrava.

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http://dx.doi.org/10.1111/ped.12676DOI Listing
October 2015

Relevance of low viral load in haemodialysed patients with chronic hepatitis C virus infection.

World J Gastroenterol 2015 May;21(18):5496-504

Jan Sperl, Sona Frankova, Renata Senkerikova, Julius Spicak, Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, 14021 Prague, Czech Republic.

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http://dx.doi.org/10.3748/wjg.v21.i18.5496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427671PMC
May 2015

NKD1 marks intestinal and liver tumors linked to aberrant Wnt signaling.

Cell Signal 2015 Feb 14;27(2):245-56. Epub 2014 Nov 14.

Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Videnska 1083142 20 Prague 4, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2014.11.008DOI Listing
February 2015

Treatment of pruritus with Prometheus dialysis and absorption system in a patient with benign recurrent intrahepatic cholestasis.

Hepatol Res 2014 Oct 2;44(10):E304-E308. Epub 2013 Dec 2.

Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland.

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http://dx.doi.org/10.1111/hepr.12262DOI Listing
October 2014

ABCB4 mutations underlie hormonal cholestasis but not pediatric idiopathic gallstones.

World J Gastroenterol 2014 May;20(19):5867-74

Milan Jirsa, Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, 14021 Prague, Czech Republic.

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http://dx.doi.org/10.3748/wjg.v20.i19.5867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024796PMC
May 2014

New insights in bilirubin metabolism and their clinical implications.

World J Gastroenterol 2013 Oct;19(38):6398-407

Eva Sticova, Milan Jirsa, Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, 14021 Prague 4, Czech Republic.

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http://dx.doi.org/10.3748/wjg.v19.i38.6398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801310PMC
October 2013

ATP8B1 gene expression is driven by a housekeeping-like promoter independent of bile acids and farnesoid X receptor.

PLoS One 2012 10;7(12):e51650. Epub 2012 Dec 10.

Institute of Liver Studies, King's College London School of Medicine, at King's College Hospital, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0051650PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518472PMC
June 2013

Dubin-Johnson syndrome coinciding with colon cancer and atherosclerosis.

World J Gastroenterol 2013 Feb;19(6):946-50

Center for Experimental Medicine, Institute for Clinical and Experimental Medicine, 14021 Prague 4, Czech Republic.

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http://dx.doi.org/10.3748/wjg.v19.i6.946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574894PMC
February 2013

Nasobiliary drainage in an episode of intrahepatic cholestasis in a child with mild ABCB11 disease.

J Pediatr Gastroenterol Nutr 2012 Jul;55(1):88-90

First Department of Pediatrics, Aghia Sophia Children's Hospital, Athens, Greece.

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http://dx.doi.org/10.1097/MPG.0b013e31822f2bdaDOI Listing
July 2012

Glucocerebrosidase gene has an alternative upstream promoter, which has features and expression characteristic of housekeeping genes.

Blood Cells Mol Dis 2011 Mar 20;46(3):239-45. Epub 2011 Jan 20.

Institute of Inherited Metabolic Disorders, Charles University, 1st Faculty of Medicine and University Hospital, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.bcmd.2010.12.011DOI Listing
March 2011

[Molecular diagnosis of hereditary canalicular cholestasis and familial hyperbilirubinemias].

Authors:
Milan Jirsa

Cas Lek Cesk 2011 ;150(1):7-13

Institut klinické a experimentální medicíny Praha, Laborator experimentální hepatologie, Pracoviste experimentální medicíny.

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March 2011

Novel ABCB11 mutations in a Thai infant with progressive familial intrahepatic cholestasis.

World J Gastroenterol 2009 Sep;15(34):4339-42

Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2744194PMC
http://dx.doi.org/10.3748/wjg.15.4339DOI Listing
September 2009

Wilson disease as a cause of liver injury in cystic fibrosis.

J Cyst Fibros 2009 Jan 23;8(1):63-5. Epub 2008 Oct 23.

Department of Pediatrics, Charles University 2nd Medical School and Faculty Hospital Motol, V Uvalu 84, 150 06 Praha 5, Czech Republic.

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http://dx.doi.org/10.1016/j.jcf.2008.09.003DOI Listing
January 2009

CYP7A1 promoter polymorphism -203A>C affects bile salt synthesis rate in patients after ileal resection.

J Lipid Res 2008 Dec 26;49(12):2664-7. Epub 2008 Aug 26.

Department of Clinical Biochemistry and Laboratory Diagnostics, 1st Faculty of Medicine, Charles University in Prague.

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http://dx.doi.org/10.1194/jlr.M800364-JLR200DOI Listing
December 2008

1H MR spectroscopy as a diagnostic tool for cerebral creatine deficiency.

MAGMA 2008 Sep 26;21(5):327-32. Epub 2008 Aug 26.

MR-Unit, Department of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Videnska 1958/9, 140 21, Prague 4, Czech Republic.

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http://dx.doi.org/10.1007/s10334-008-0137-zDOI Listing
September 2008

Highly sensitive method for quantitative determination of bilirubin in biological fluids and tissues.

J Chromatogr B Analyt Technol Biomed Life Sci 2008 May 18;867(1):37-42. Epub 2008 Mar 18.

Institute of Clinical Biochemistry and Laboratory Diagnostics, 1st Faculty of Medicine, Charles University in Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.jchromb.2008.03.005DOI Listing
May 2008

Revised King's College score for liver transplantation in adult patients with Wilson's disease.

Liver Transpl 2007 Jan;13(1):55-61

Department of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

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http://dx.doi.org/10.1002/lt.20920DOI Listing
January 2007

5-aminolaevulinic acid-induced fluorescence cystoscopy during transurethral resection reduces the risk of recurrence in stage Ta/T1 bladder cancer.

BJU Int 2005 Oct;96(6):798-802

Department of Urology, General Teaching Hospital, Charles University, Postgraduate Institute, Praha, Czech Republic.

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http://dx.doi.org/10.1111/j.1464-410X.2004.05715.xDOI Listing
October 2005

Indel in the FIC1/ATP8B1 gene-a novel rare type of mutation associated with benign recurrent intrahepatic cholestasis.

Hepatol Res 2004 Sep;30(1):1-3

Laboratory of Experimental Hepatology, Institute of Clinical and Experimental Medicine, Videnska 1958/9, 140 21 Praha 4 - Krc, Czech Republic.

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http://dx.doi.org/10.1016/j.hepres.2004.05.001DOI Listing
September 2004

Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice.

J Hepatol 2003 Jun;38(6):710-6

Department of Experimental Hepatology, AMC Liver Center, Academic Medical Center, Meibergdreef 69-71, Amsterdam 1105 BK, The Netherlands.

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http://dx.doi.org/10.1016/s0168-8278(03)00093-xDOI Listing
June 2003

Experimental photodynamic therapy with MESO-tetrakisphenylporphyrin (TPP) in liposomes leads to disintegration of human amelanotic melanoma implanted to nude mice.

Int J Cancer 2003 Feb;103(5):693-702

Department of Membrane Transport Biophysics, Institute of Physiology, Academy of Sciences, Prague, Czech Republic.

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http://dx.doi.org/10.1002/ijc.10857DOI Listing
February 2003

Genetic background of cholesterol gallstone disease.

Biochim Biophys Acta 2003 Jan;1637(1):1-19

Department of Experimental Hepatology, AMC Liver Center S1-172, Academic Medical Center, Meibergdreef 69-71, 1105 BK, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/s0925-4439(02)00173-4DOI Listing
January 2003

Gilbert syndrome and ischemic heart disease: a protective effect of elevated bilirubin levels.

Atherosclerosis 2002 Feb;160(2):449-56

4th Department of Internal Medicine, 1st Medical Faculty, Charles University Prague, U Nemocnice 2, 128 08 Prague, Czech Republic.

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http://dx.doi.org/10.1016/s0021-9150(01)00601-3DOI Listing
February 2002

Influence of losartan and enalapril on urinary excretion of 8-isoprostane in experimental nephrotic syndrome.

Med Sci Monit 2002 Feb;8(2):BR69-74

Department of Nephrology, 1st Department of Medicine, 1st Medicine Faculty, Charles University, U nemocnice 2, 120 00 Prague 2, Czech Republic.

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February 2002

Soluble cytokine receptors in renal vasculitis and lupus nephritis.

Med Sci Monit 2002 Jan;8(1):BR24-9

1st Department of Medicine, 1st Medicine Faculty, Charles University, Prague, Czech Republic.

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January 2002