Publications by authors named "Milad Dodangeh"

5 Publications

  • Page 1 of 1

Non-alcoholic fatty liver and lipid profile status in patients with melasma: A case-control study.

J Cosmet Dermatol 2021 Feb 20. Epub 2021 Feb 20.

Dermatology Department, Rasool Akram Medical Complex, Iran University of Medical Sciences (IUMS), Tehran, Iran.

Background: There are pieces of evidence regarding the association between melasma and metabolic syndrome. To assess the prevalence and grade of nonalcoholic fatty liver and lipid profile status in patients with melasma, we designed this case-control study.

Methods: This study was performed on 30 consecutive women with melasma who referred to the dermatology clinic of the hospital as the case group and 34 healthy women. For all participants, serum lipid profiles and liver enzymes were checked. Also, the existence of fatty liver was assessed by ultrasonography.

Results: Except for serum level of LDL (low-density lipoprotein) that was significantly higher in the melasma group than in the healthy group (104.23 ± 25.00 mg/dl versus 89.85 ± 23.00 mg/dl, p = 0.020), the level of other parameters including other lipid profiles, blood sugar, or liver enzymes was similar in both groups. In ultrasonography, the overall prevalence of fatty liver was 23.3% in the melasma group and 20.6% in the control group, and no difference was found between the two groups in grade of fatty liver (p = 0.791).

Conclusion: The study showed a higher serum LDL level in patients with melasma compared to women without melasma, but there was no difference between the groups in prevalence or grade of fatty liver.
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http://dx.doi.org/10.1111/jocd.14014DOI Listing
February 2021

The healing effects of facial BOTOX injection on symptoms of depression alongside its effects on beauty preservation.

J Cosmet Dermatol 2021 Feb 10. Epub 2021 Feb 10.

The British Board of Antiaging & Integrated Medicine, London, UK.

Background: Beauty is closely associated with a sense of calm, confidence, and hope for a better life. Therefore, it is expected that improving the appearance or even correcting one's view of appearance can prevent depression and even improve different degrees of depression in individuals.

Aims: Investigation of whether using botulinum injections (a common method of improving facial esthetics) can improve the degree of depression in clients.

Methods: This prospective interventional before-after study was conducted on 121 consecutive individuals referred for beautifying the face. Before performing the interventional procedure by facial botulinum injection as well as one month later, the depression status was examined by the Beck Depression Inventory II (BDI) questionnaire.

Results: The mean baseline depression score dropped from 18.9 ± 4.8 to 10.6 ± 2.9 during the follow-up time (P < .001). Using the multivariable linear regression modeling and with the presence of baseline parameters, the main determinants of improving depression score included young ages (beta = -0.541, P = .001), higher educational level (beta = 0.595, P = .015), and previous experiences of botulinum toxin use (beta = 1.072, P = .036).

Conclusion: The improvement in people's moods along with correction of their facial defects following botulinum toxin injections would be expected.
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http://dx.doi.org/10.1111/jocd.13990DOI Listing
February 2021

The role of topical timolol in wound healing and the treatment of vascular lesions: A narrative review.

Dermatol Ther 2021 Mar 13;34(2):e14847. Epub 2021 Feb 13.

Department of Dermatology, Rasool Akram Medical Complex, Iran University of Medical Sciences (IUMS), Tehran, Iran.

Beta-2 adrenergic receptors are the only subgroup of beta-adrenergic receptors expressed in the membrane of large cells, including skin keratinocytes, fibroblasts, and melanocytes. Alterations in the function or concentration of β2 adrenoreceptors related to keratinocytes are associated with some skin conditions. Some findings suggest the role of β2 adrenoreceptors in maintaining the function and integrity of the epidermis. Beta-receptor antagonists can be systemically and topically effective in healing hemangioma, paronychia, vasculitis ulcer, tufted angioma, acute and chronic wounds. Most studies with a strong design on this subject deal with the systemic form, but recently, numerous case and group reports and smaller studies have focused on topical forms, especially topical timolol. The present comprehensive review study surveys the role of topical timolol in acute and chronic wound healing in the field of dermatology.
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http://dx.doi.org/10.1111/dth.14847DOI Listing
March 2021

What we know about 2019-nCoV in Iran in the early stage?

Virusdisease 2020 May 22:1-3. Epub 2020 May 22.

Student Research Committee (SRC), Faculty of Medicine, Iran University of Medical Sciences (IUMS), Shahid Hemmat Highway, Tehran, 1449614535 Iran.

On 10 January 2020, a new coronavirus causing a pneumonia outbreak spread rapidly in all of the World. On 19 February 2020, the first official announcement of death from 2019-Nov was made in Iran. As of 7 March 2020, there were 101,927 confirmed cases of Covid-19 infection, including 3486 deaths, reported in the World. In the eastern and Mediterranean region Iran with 4747 confirmed cases of Covid-19 infection and 124 deaths, is in the critical stage. Therefore, there is a matter of urgency combating this new virus and stopping the epidemic. Here, we focus on symptoms and the development of fast diagnosis methods, as well as potential management to prevent or treat the Covid-19 infection.
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http://dx.doi.org/10.1007/s13337-020-00596-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243951PMC
May 2020

Iranian healthcare system against COVID-19.

Germs 2020 Jun 2;10(2):112-114. Epub 2020 Jun 2.

Independent researcher, Tehran, Iran.

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http://dx.doi.org/10.18683/germs.2020.1192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330514PMC
June 2020