Mikko J Frilander

Mikko J Frilander

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Mikko J Frilander

Mikko J Frilander

Publications by authors named "Mikko J Frilander"

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Diverse and variable virus communities in wild plant populations revealed by metagenomic tools.

PeerJ 2019 11;7:e6140. Epub 2019 Jan 11.

Research Centre for Ecological Change, Organismal and Evolutionary Biology Research Programme, University of Helsinki, Finland.

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http://dx.doi.org/10.7717/peerj.6140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330959PMC
January 2019

Minor spliceosome and disease.

Semin Cell Dev Biol 2018 07 14;79:103-112. Epub 2017 Dec 14.

Institute of Biotechnology, PL56 (Viikinkaari 5), 000014, University of Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2017.09.036DOI Listing
July 2018

IntEREst: intron-exon retention estimator.

BMC Bioinformatics 2018 04 11;19(1):130. Epub 2018 Apr 11.

Institute of Biotechnology, University of Helsinki, P.O. Box 56 (Viikinkaari 5), FI-00014, Helsinki, Finland.

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http://dx.doi.org/10.1186/s12859-018-2122-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896110PMC
April 2018

The emerging role of minor intron splicing in neurological disorders.

Cell Stress 2018 Feb 22;2(3):40-54. Epub 2018 Feb 22.

Department of Chemistry and Biochemistry, University of Bern, CH-3012 Bern, Switzerland.

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http://dx.doi.org/10.15698/cst2018.03.126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558932PMC
February 2018

Genome sequences of a capulavirus infecting Plantago lanceolata in the Åland archipelago of Finland.

Arch Virol 2017 Jul 10;162(7):2041-2045. Epub 2017 Mar 10.

CIRAD-INRA-SupAgro, UMR BGPI, Campus International de Montferrier-Baillarguet, 34398, Montpellier Cedex-5, France.

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http://dx.doi.org/10.1007/s00705-017-3298-0DOI Listing
July 2017

Virus-encapsulated DNA origami nanostructures for cellular delivery.

Nano Lett 2014 19;14(4):2196-200. Epub 2014 Mar 19.

Molecular Materials, Department of Applied Physics, Aalto University , FI-00076 Aalto, Finland.

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http://dx.doi.org/10.1021/nl500677jDOI Listing
October 2015

Regulation of gene expression through inefficient splicing of U12-type introns.

RNA Biol 2014 ;11(11):1325-9

a Institute of Biotechnology; Genome Biology Research Program ; University of Helsinki ; Helsinki , Finland.

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http://dx.doi.org/10.1080/15476286.2014.996454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615840PMC
October 2015

Global analysis of the nuclear processing of transcripts with unspliced U12-type introns by the exosome.

Nucleic Acids Res 2014 Jun 21;42(11):7358-69. Epub 2014 May 21.

Institute of Biotechnology, P.O. Box 56, FI-00014 University of Helsinki, Finland

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http://dx.doi.org/10.1093/nar/gku391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066798PMC
June 2014

Defective minor spliceosome mRNA processing results in isolated familial growth hormone deficiency.

EMBO Mol Med 2014 03 30;6(3):299-306. Epub 2014 Jan 30.

Departments of Endocrinology and Pediatrics, Hospital Infantil Universitario Niño Jesús Universidad Autónoma de Madrid, Madrid, Spain.

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http://dx.doi.org/10.1002/emmm.201303573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958305PMC
March 2014

The significant other: splicing by the minor spliceosome.

Wiley Interdiscip Rev RNA 2013 Jan-Feb;4(1):61-76. Epub 2012 Oct 16.

Institute of Biotechnology, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1002/wrna.1141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584512PMC
June 2013

HnRNPH1/H2, U1 snRNP, and U11 snRNP cooperate to regulate the stability of the U11-48K pre-mRNA.

RNA 2013 Mar 18;19(3):380-9. Epub 2013 Jan 18.

Institute of Biotechnology, PL 56, FIN-00014 University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1261/rna.036715.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677248PMC
March 2013

Requirement of TFIIH kinase subunit Mat1 for RNA Pol II C-terminal domain Ser5 phosphorylation, transcription and mRNA turnover.

Nucleic Acids Res 2011 Jul 8;39(12):5025-35. Epub 2011 Mar 8.

Institute of Biotechnology, University of Helsinki, PO Box 56 Viikinkaari 9, 00014 University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1093/nar/gkr107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130277PMC
July 2011

Functional genomics of life history variation in a butterfly metapopulation.

Mol Ecol 2011 May 17;20(9):1813-28. Epub 2011 Mar 17.

Department of Biology, 208 Mueller Lab, Pennsylvania State University, University Park, PA 16802, USA.

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http://dx.doi.org/10.1111/j.1365-294X.2011.05062.xDOI Listing
May 2011

Genetics. Minor splicing, disrupted.

Science 2011 Apr;332(6026):184-5

Institute of Biotechnology, Program in Genome Biology, PL 56 (Viikinkaari 9), University of Helsinki, 00014 Helsinki, Finland.

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http://dx.doi.org/10.1126/science.1205503DOI Listing
April 2011

Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs.

Dev Biol 2010 Apr 25;340(2):355-68. Epub 2010 Jan 25.

Institute of Biotechnology, Developmental Biology Program, PO Box 56, University of Helsinki, FIN-00014, Helsinki, Finland.

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http://linkinghub.elsevier.com/retrieve/pii/S001216061000036
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http://dx.doi.org/10.1016/j.ydbio.2010.01.019DOI Listing
April 2010

An ancient mechanism for splicing control: U11 snRNP as an activator of alternative splicing.

Mol Cell 2010 Mar;37(6):821-33

Institute of Biotechnology, University of Helsinki, Helsinki FIN-00014, Finland.

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http://dx.doi.org/10.1016/j.molcel.2010.02.014DOI Listing
March 2010

Nucleotide polymorphism at a gene (Pgi) under balancing selection in a butterfly metapopulation.

Mol Biol Evol 2010 Feb 30;27(2):267-81. Epub 2009 Sep 30.

Department of Biological and Environmental Sciences, University of Helsinki, Finland.

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http://mbe.oxfordjournals.org/content/27/2/267.full.pdf
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http://mbe.oxfordjournals.org/cgi/doi/10.1093/molbev/msp227
Publisher Site
http://dx.doi.org/10.1093/molbev/msp227DOI Listing
February 2010

Weight and nutrition affect pre-mRNA splicing of a muscle gene associated with performance, energetics and life history.

J Exp Biol 2008 Dec;211(Pt 23):3653-60

Department of Biology, 208 Mueller Laboratory, Pennsylvania State University, University Park, PA 16802, USA.

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http://dx.doi.org/10.1242/jeb.023903DOI Listing
December 2008

Minor spliceosome components are predominantly localized in the nucleus.

Proc Natl Acad Sci U S A 2008 Jun 16;105(25):8655-60. Epub 2008 Jun 16.

Institute of Biotechnology, PL 56 (Viikinkaari 9), and Institute of Biomedicine, Biomedicum Helsinki, PL 63 (Haartmaninkatu 8), University of Helsinki, FIN-00014, Helsinki, Finland.

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http://dx.doi.org/10.1073/pnas.0803646105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2438382PMC
June 2008

The U11-48K protein contacts the 5' splice site of U12-type introns and the U11-59K protein.

Mol Cell Biol 2008 May 17;28(10):3548-60. Epub 2008 Mar 17.

Institute of Biotechnology, PL 56 Viikinkaari 9, 00014 University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1128/MCB.01928-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423181PMC
May 2008

Transcriptional co-activator protein p100 interacts with snRNP proteins and facilitates the assembly of the spliceosome.

Nucleic Acids Res 2007 18;35(13):4485-94. Epub 2007 Jun 18.

Department of Immunology, Tianjin Medical University, Heping District Qixiangtai Road No.22, 300070 Tianjin, PR China.

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http://dx.doi.org/10.1093/nar/gkm470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1935017PMC
August 2007

The abundance of the spliceosomal snRNPs is not limiting the splicing of U12-type introns.

RNA 2006 Oct 6;12(10):1883-92. Epub 2006 Sep 6.

Institute of Biotechnology, Program on Developmental Biology, PL56 (Viikinkaari 9), 00014 University of Helsinki, Finland.

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http://dx.doi.org/10.1261/rna.213906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1581978PMC
October 2006

Proximity of the U12 snRNA with both the 5' splice site and the branch point during early stages of spliceosome assembly.

Mol Cell Biol 2005 Jun;25(12):4813-25

Institute of Biotechnology, Program on Developmental Biology, PL56 (Viikinkaari 9), 00014 University of Helsinki, Finland.

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http://dx.doi.org/10.1128/MCB.25.12.4813-4825.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140575PMC
June 2005

Identification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in Drosophila.

Proc Natl Acad Sci U S A 2004 Jun 21;101(26):9584-9. Epub 2004 Jun 21.

Department of Cellular Biochemistry, Max Planck Institute of Biophysical Chemistry, 37077 Goettingen, Germany.

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http://dx.doi.org/10.1073/pnas.0403400101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC470718PMC
June 2004

[RNA--the original chemistry of life].

Duodecim 2002 ;118(23):2419-22

Biotekniikan Instituutti PL 56, 00014 Helsingin yliopisto.

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March 2003

Nonspecific nucleoside triphosphatase P4 of double-stranded RNA bacteriophage phi6 is required for single-stranded RNA packaging and transcription.

J Virol 2002 Oct;76(20):10122-7

Department of Biosciences. Institute of Biotechnology, Viikki Biocenter, FIN-00014 University of Helsinki, Finland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC136547PMC
http://dx.doi.org/10.1128/jvi.76.20.10122-10127.2002DOI Listing
October 2002

Branchpoint selection in the splicing of U12-dependent introns in vitro.

RNA 2002 May;8(5):579-86

Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University, New Haven, Connecticut 06536, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1370279PMC
http://dx.doi.org/10.1017/s1355838202028029DOI Listing
May 2002