Mikkel H Schierup

Mikkel H Schierup

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Mikkel H Schierup

Mikkel H Schierup

Publications by authors named "Mikkel H Schierup"

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Association Mapping and Disease: Evolutionary Perspectives.

Methods Mol Biol 2019 ;1910:533-553

Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1007/978-1-4939-9074-0_17DOI Listing
January 2019

Transcriptome profiling of fetal Klinefelter testis tissue reveals a possible involvement of long non-coding RNAs in gonocyte maturation.

Hum Mol Genet 2018 02;27(3):430-439

Department of Growth and Reproduction, Copenhagen University Hospital (Rigshospitalet), DK-2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1093/hmg/ddx411DOI Listing
February 2018

Assembly and analysis of 100 full MHC haplotypes from the Danish population.

Genome Res 2017 09 3;27(9):1597-1607. Epub 2017 Aug 3.

Bioinformatics Research Centre, Aarhus University, 8000 Aarhus C., Denmark.

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http://dx.doi.org/10.1101/gr.218891.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580718PMC
September 2017

Nationwide Genomic Study in Denmark Reveals Remarkable Population Homogeneity.

Genetics 2016 Oct 17;204(2):711-722. Epub 2016 Aug 17.

Bioinformatics Research Centre, Aarhus University, 8000, Denmark Centre for Biocultural History, Aarhus University, 8000, Denmark.

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http://dx.doi.org/10.1534/genetics.116.189241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068857PMC
October 2016

A genomic history of Aboriginal Australia.

Nature 2016 Oct 21;538(7624):207-214. Epub 2016 Sep 21.

Centre for GeoGenetics, Natural History Museum of Denmark, University of Copenhagen, Øster Voldgade 5-7, 1350 Copenhagen, Denmark.

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http://dx.doi.org/10.1038/nature18299DOI Listing
October 2016

Demographic History of the Genus Pan Inferred from Whole Mitochondrial Genome Reconstructions.

Genome Biol Evol 2016 07 3;8(6):2020-30. Epub 2016 Jul 3.

Departament de Ciències Experimentals i de la Salut, Institut de Biologia Evolutiva (CSIC-UPF), Barcelona, Spain Catalan Institution of Research and Advanced Studies (ICREA), Passeig de Lluís Companys, Barcelona, Spain CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain

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http://dx.doi.org/10.1093/gbe/evw124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943195PMC
July 2016

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.

Am J Hum Genet 2015 Oct;97(4):576-92

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. Electronic address:

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http://biorxiv.org/content/biorxiv/early/2015/03/01/015859.f
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http://linkinghub.elsevier.com/retrieve/pii/S000292971500365
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http://dx.doi.org/10.1016/j.ajhg.2015.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596916PMC
October 2015

Strong Selective Sweeps on the X Chromosome in the Human-Chimpanzee Ancestor Explain Its Low Divergence.

PLoS Genet 2015 Aug 14;11(8):e1005451. Epub 2015 Aug 14.

Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark; Department of Bioscience, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1371/journal.pgen.1005451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537231PMC
August 2015

Unraveling recombination rate evolution using ancestral recombination maps.

Bioessays 2014 Sep 14;36(9):892-900. Epub 2014 Jul 14.

Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1002/bies.201400047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314685PMC
September 2014

Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population.

Eur J Hum Genet 2014 Aug 22;22(8):1040-5. Epub 2014 Jan 22.

1] Bioinformatics Research Centre, Aarhus University, C.F. Mollers Alle, 8000 Aarhus C, Denmark [2] Department of Bioscience, Aarhus University, Ny Munkegade, 8000 Aarhus C., Denmark.

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http://dx.doi.org/10.1038/ejhg.2013.282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350597PMC
August 2014

Great ape genetic diversity and population history.

Nature 2013 Jul 3;499(7459):471-5. Epub 2013 Jul 3.

Institut de Biologia Evolutiva, CSIC-Universitat Pompeu Fabra, PRBB, Doctor Aiguader 88, Barcelona, Catalonia 08003, Spain.

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http://dx.doi.org/10.1038/nature12228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822165PMC
July 2013

Association mapping and disease: evolutionary perspectives.

Methods Mol Biol 2012 ;856:275-91

deCODE Genetics, Reykjavik, Iceland.

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http://dx.doi.org/10.1007/978-1-61779-585-5_11DOI Listing
July 2012

Genomic determinants of protein evolution and polymorphism in Arabidopsis.

Genome Biol Evol 2011 16;3:1210-9. Epub 2011 Sep 16.

Department of Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Sweden.

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http://dx.doi.org/10.1093/gbe/evr094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296466PMC
April 2012

Comparative and demographic analysis of orang-utan genomes.

Authors:
Devin P Locke LaDeana W Hillier Wesley C Warren Kim C Worley Lynne V Nazareth Donna M Muzny Shiaw-Pyng Yang Zhengyuan Wang Asif T Chinwalla Pat Minx Makedonka Mitreva Lisa Cook Kim D Delehaunty Catrina Fronick Heather Schmidt Lucinda A Fulton Robert S Fulton Joanne O Nelson Vincent Magrini Craig Pohl Tina A Graves Chris Markovic Andy Cree Huyen H Dinh Jennifer Hume Christie L Kovar Gerald R Fowler Gerton Lunter Stephen Meader Andreas Heger Chris P Ponting Tomas Marques-Bonet Can Alkan Lin Chen Ze Cheng Jeffrey M Kidd Evan E Eichler Simon White Stephen Searle Albert J Vilella Yuan Chen Paul Flicek Jian Ma Brian Raney Bernard Suh Richard Burhans Javier Herrero David Haussler Rui Faria Olga Fernando Fleur Darré Domènec Farré Elodie Gazave Meritxell Oliva Arcadi Navarro Roberta Roberto Oronzo Capozzi Nicoletta Archidiacono Giuliano Della Valle Stefania Purgato Mariano Rocchi Miriam K Konkel Jerilyn A Walker Brygg Ullmer Mark A Batzer Arian F A Smit Robert Hubley Claudio Casola Daniel R Schrider Matthew W Hahn Victor Quesada Xose S Puente Gonzalo R Ordoñez Carlos López-Otín Tomas Vinar Brona Brejova Aakrosh Ratan Robert S Harris Webb Miller Carolin Kosiol Heather A Lawson Vikas Taliwal André L Martins Adam Siepel Arindam Roychoudhury Xin Ma Jeremiah Degenhardt Carlos D Bustamante Ryan N Gutenkunst Thomas Mailund Julien Y Dutheil Asger Hobolth Mikkel H Schierup Oliver A Ryder Yuko Yoshinaga Pieter J de Jong George M Weinstock Jeffrey Rogers Elaine R Mardis Richard A Gibbs Richard K Wilson

Nature 2011 Jan;469(7331):529-33

The Genome Center at Washington University, Washington University School of Medicine, 4444 Forest Park Avenue, Saint Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1038/nature09687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3060778PMC
January 2011

Insertion and deletion processes in recent human history.

PLoS One 2010 Jan 19;5(1):e8650. Epub 2010 Jan 19.

Bioinformatics Research Center, C. F. Møllers Alle, Arhus, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008650PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808225PMC
January 2010

Increased rate of human mutations where DNA and RNA polymerases collide.

Trends Genet 2009 Dec 23;25(12):523-7. Epub 2009 Oct 23.

Department of Genetics and Ecology, Aarhus University, Denmark.

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http://dx.doi.org/10.1016/j.tig.2009.10.002DOI Listing
December 2009

Ancestral population genomics: the coalescent hidden Markov model approach.

Genetics 2009 Sep 6;183(1):259-74. Epub 2009 Jul 6.

Bioinformatics Research Center, Aarhus University, C. F. Møllers Alle 8, Bldg. 1110, DK-8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1534/genetics.109.103010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746150PMC
September 2009

Recent speciation of Capsella rubella from Capsella grandiflora, associated with loss of self-incompatibility and an extreme bottleneck.

Proc Natl Acad Sci U S A 2009 Mar 23;106(13):5246-51. Epub 2009 Mar 23.

Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1073/pnas.0808012106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659713PMC
March 2009

Local phylogeny mapping of quantitative traits: higher accuracy and better ranking than single-marker association in genomewide scans.

Genetics 2009 Feb 8;181(2):747-53. Epub 2008 Dec 8.

Bioinformatics Research Center, University of Aarhus, DK-8000 Arhus C, Denmark.

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http://dx.doi.org/10.1534/genetics.108.092643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644962PMC
February 2009

RNA exosome depletion reveals transcription upstream of active human promoters.

Science 2008 Dec 4;322(5909):1851-4. Epub 2008 Dec 4.

Centre for mRNP Biogenesis and Metabolism, Department of Molecular Biology, C. F. Møllers Alle, Building 1130, Aarhus University, Denmark.

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http://dx.doi.org/10.1126/science.1164096DOI Listing
December 2008

Selection at work in self-incompatible Arabidopsis lyrata. II. Spatial distribution of S haplotypes in Iceland.

Genetics 2008 Oct 9;180(2):1051-9. Epub 2008 Sep 9.

Department of Ecology and Genetics, Institute of Biology, University of Aarhus, 8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1534/genetics.108.088799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2567355PMC
October 2008

Repeated adaptive introgression at a gene under multiallelic balancing selection.

PLoS Genet 2008 Aug 29;4(8):e1000168. Epub 2008 Aug 29.

Université des Sciences et Technologies de Lille 1, Laboratoire Génétique et Evolution des Populations Végétales, CNRS UMR 8016, France.

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http://dx.doi.org/10.1371/journal.pgen.1000168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2517234PMC
August 2008

When gametophytic self-incompatibility meets gynodioecy.

Genet Res (Camb) 2008 Feb;90(1):27-35

Institute of Biological Sciences, Department of Ecology and Genetics and Bioinformatics Research Center, University of Aarhus, Aarhus, Denmark.

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http://dx.doi.org/10.1017/S0016672307009007DOI Listing
February 2008

Genomic relationships and speciation times of human, chimpanzee, and gorilla inferred from a coalescent hidden Markov model.

PLoS Genet 2007 Feb 30;3(2):e7. Epub 2006 Nov 30.

Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, United States of America.

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https://dx.plos.org/10.1371/journal.pgen.0030007
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http://dx.doi.org/10.1371/journal.pgen.0030007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1802818PMC
February 2007

Whole genome association mapping by incompatibilities and local perfect phylogenies.

BMC Bioinformatics 2006 Oct 16;7:454. Epub 2006 Oct 16.

Department of Statistics, University of Oxford, UK.

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http://dx.doi.org/10.1186/1471-2105-7-454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1624851PMC
October 2006

GeneRecon--a coalescent based tool for fine-scale association mapping.

Bioinformatics 2006 Sep 21;22(18):2317-8. Epub 2006 Apr 21.

Bioinformatics Research Center, University of Aarhus Høegh-Guldbergs Gade 10, DK-8000 Arhus C, Denmark.

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http://dx.doi.org/10.1093/bioinformatics/btl153DOI Listing
September 2006

The effective size of the Icelandic population and the prospects for LD mapping: inference from unphased microsatellite markers.

Eur J Hum Genet 2006 Sep 31;14(9):1044-53. Epub 2006 May 31.

Bioinformatics Research Center, University of Aarhus, Høegh-Guldbergs Gade 10, DK-8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1038/sj.ejhg.5201669DOI Listing
September 2006

The transition to self-compatibility in Arabidopsis thaliana and evolution within S-haplotypes over 10 Myr.

Mol Biol Evol 2006 Sep 16;23(9):1741-50. Epub 2006 Jun 16.

Ecology and Genetics, Institute of Biological Sciences, University of Aarhus, Denmark.

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http://dx.doi.org/10.1093/molbev/msl042DOI Listing
September 2006

Long-term stability and effective population size in North Sea and Baltic Sea cod (Gadus morhua).

Mol Ecol 2006 Feb;15(2):321-31

Department of Inland Fisheries, Danish Institute for Fisheries Research, DK-8600 Silkeborg, Denmark.

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http://dx.doi.org/10.1111/j.1365-294X.2005.02777.xDOI Listing
February 2006

Selection at work in self-incompatible Arabidopsis lyrata: mating patterns in a natural population.

Genetics 2006 Jan 12;172(1):477-84. Epub 2005 Sep 12.

Department of Ecology and Genetics, Institute of Biological Sciences, University of Aarhus, 8000 Aarhus C., Denmark.

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http://dx.doi.org/10.1534/genetics.105.045682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456200PMC
January 2006

Evidence of recombination among early-vaccination era measles virus strains.

BMC Evol Biol 2005 Oct 6;5:52. Epub 2005 Oct 6.

Bioinformatics Research Center (BiRC), University of Aarhus, Hoegh Guldbergs Gade 10, DK-8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1186/1471-2148-5-52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262704PMC
October 2005

CoaSim: a flexible environment for simulating genetic data under coalescent models.

BMC Bioinformatics 2005 Oct 14;6:252. Epub 2005 Oct 14.

Bioinformatics Research Center, University of Aarhus, Høegh Guldbergsgade 10, 8000 Arhus C, Denmark.

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http://dx.doi.org/10.1186/1471-2105-6-252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1274299PMC
October 2005

Haplotype structure of the stigmatic self-incompatibility gene in natural populations of Arabidopsis lyrata.

Mol Biol Evol 2003 Nov 27;20(11):1741-53. Epub 2003 Jun 27.

Institute of Cell, Animal and Population Biology, University of Edinburgh, Ashworth Laboratories, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1093/molbev/msg170DOI Listing
November 2003

Relative roles of mutation and recombination in generating allelic polymorphism at an MHC class II locus in Peromyscus maniculatus.

Genet Res 2003 Oct;82(2):89-99

Plant Sciences Department, MSU Bozeman, Bozeman, MT 59717, USA.

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http://dx.doi.org/10.1017/s0016672303006347DOI Listing
October 2003

Diversity and linkage of genes in the self-incompatibility gene family in Arabidopsis lyrata.

Genetics 2003 Aug;164(4):1519-35

Institute of Cell, Animal and Population Biology, University of Edinburgh, Ashworth Laboratories, King's Buildings, West Mains Road, Edinburgh EH9 3JT, Scotland, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462643PMC
August 2003

MATE AVAILABILITY AND FECUNDITY SELECTION IN MULTI-ALLELIC SELF-INCOMPATIBILITY SYSTEMS IN PLANTS.

Evolution 1998 Feb;52(1):19-29

Department of Ecology and Genetics, University of Aarhus, DK-8000, Aarhus C., Denmark.

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http://dx.doi.org/10.1111/j.1558-5646.1998.tb05134.xDOI Listing
February 1998