Mikiko Tohyama

Mikiko Tohyama

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Mikiko Tohyama

Mikiko Tohyama

Publications by authors named "Mikiko Tohyama"

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A case of woolly hair nevus, multiple linear pigmentation, and epidermal nevi with somatic HRAS p.G12S mutation.

Pediatr Dermatol 2019 May 12;36(3):368-371. Epub 2019 Mar 12.

Department of Biochemistry, Keio University School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/pde.13783DOI Listing
May 2019

A Case of Perforating Folliculitis Induced by Vemurafenib.

Acta Derm Venereol 2019 Feb;99(2):230-231

Department of Dermatology , Ehime University Graduate School of Medicine, 791-0295 Toon, Japan.

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http://www.medicaljournals.se/acta/content/abstract/10.2340/
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http://dx.doi.org/10.2340/00015555-3059DOI Listing
February 2019

Acquired Partial Lipodystrophy Associated with Anti-Mi-2 Antibody-positive Adult-onset Dermatomyositis.

Acta Derm Venereol 2019 Jan;99(1):95-96

Department of Dermatology , Ehime University Graduate School of Medicine, 791-0295 Toon, Japan.

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http://dx.doi.org/10.2340/00015555-3026DOI Listing
January 2019

The microbiome of the "sterile" pustules in palmoplantar pustulosis.

Exp Dermatol 2018 12;27(12):1372-1377

Department of Dermatology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime, Japan.

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http://doi.wiley.com/10.1111/exd.13791
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http://dx.doi.org/10.1111/exd.13791DOI Listing
December 2018

Heparinoid suppresses Der p-induced IL-1β production by inhibiting ERK and p38 MAPK pathways in keratinocytes.

Exp Dermatol 2018 09 28;27(9):981-988. Epub 2018 Jun 28.

Department of Dermatology, Ehime University Graduate School of Medicine, Toon City, Japan.

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http://dx.doi.org/10.1111/exd.13685DOI Listing
September 2018

Reduced-HMGB1 suppresses poly(I:C)-induced inflammation in keratinocytes.

J Dermatol Sci 2018 May 2;90(2):154-165. Epub 2018 Feb 2.

Department of Dermatology, Ehime University Graduate School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2018.01.007DOI Listing
May 2018

Case of thymoma-associated cutaneous graft-versus-host disease-like disease successfully improved by narrowband ultraviolet B phototherapy.

J Dermatol 2018 Apr 7;45(4):479-482. Epub 2017 Dec 7.

Department of Dermatology, Ehime University Graduate School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1111/1346-8138.14176DOI Listing
April 2018

Epidermal keratinocytes sense dsRNA via the NLRP3 inflammasome, mediating interleukin (IL)-1β and IL-18 release.

Exp Dermatol 2017 10 12;26(10):904-911. Epub 2017 May 12.

Department of Dermatology, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.

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http://dx.doi.org/10.1111/exd.13334DOI Listing
October 2017

Targeted exome sequencing and chromosomal microarray for the molecular diagnosis of nevoid basal cell carcinoma syndrome.

J Dermatol Sci 2017 Jun 11;86(3):206-211. Epub 2017 Mar 11.

Department of Dermatology, Tokushima University Graduate School of Medical Science, Tokushima, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2017.02.282DOI Listing
June 2017

Two cases of genital neutrophilic sebaceous adenitis.

J Dermatol 2016 Oct;43(10):1221-1223

Department of Dermatology, Ehime University Graduate School of Medicine, Ehime, Japan.

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http://doi.wiley.com/10.1111/1346-8138.13448
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http://dx.doi.org/10.1111/1346-8138.13448DOI Listing
October 2016

Bromoderma mimicking pyoderma gangrenosum caused by commercial sedatives.

J Dermatol 2016 May 28;43(5):564-6. Epub 2015 Oct 28.

Department of Dermatology, Ehime University Graduate School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1111/1346-8138.13162DOI Listing
May 2016

Case of palmoplantar pustulosis that developed with acute glomerulonephritis.

J Dermatol 2015 Jan 12;42(1):111-2. Epub 2014 Nov 12.

Department of Dermatology, Ehime University Graduate School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1111/1346-8138.12710DOI Listing
January 2015

Pressure sore-like ulcers on acneiform papules caused by EGFR inhibitors.

Int Wound J 2014 Oct 21;11(5):569-70. Epub 2013 Mar 21.

Department of Dermatology, Ehime University Graduate School of Medicine, Toon, Japan.

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http://dx.doi.org/10.1111/iwj.12070DOI Listing
October 2014

Infantile generalized pustular psoriasis: successful disease control with intermittent etretinate.

J Dermatol 2014 May;41(5):403-6

Department of Dermatology, Ehime University Graduate School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1111/1346-8138.12481DOI Listing
May 2014

Infantile inflammatory pseudotumor of the facial nerve as a complication of epidermal nevus syndrome with cholesteatoma.

Auris Nasus Larynx 2013 Dec 19;40(6):569-72. Epub 2013 Feb 19.

Department of Otolaryngology, Ehime University School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1016/j.anl.2012.11.016DOI Listing
December 2013

Occupational trichloroethylene hypersensitivity syndrome: human herpesvirus 6 reactivation and rash phenotypes.

J Dermatol Sci 2013 Dec 16;72(3):218-24. Epub 2013 Jul 16.

Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jdermsci.2013.07.003DOI Listing
December 2013

High frequency of HLA B62 in fulminant type 1 diabetes with the drug-induced hypersensitivity syndrome.

J Clin Endocrinol Metab 2012 Dec 15;97(12):E2277-81. Epub 2012 Oct 15.

Department of Molecular and Genetic Medicine, Ehime University Graduate School of Medicine, To-on, Ehime, 791-0295 Japan.

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http://dx.doi.org/10.1210/jc.2012-2054DOI Listing
December 2012

Immunological mechanisms of epidermal damage in toxic epidermal necrolysis.

Curr Opin Allergy Clin Immunol 2012 Aug;12(4):376-82

Department of Dermatology, Ehime University Graduate School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1097/ACI.0b013e328355b865DOI Listing
August 2012

[Drug-induced hypersensitivity syndrome].

Authors:
Mikiko Tohyama

Nihon Rinsho 2012 Aug;70 Suppl 6:498-502

Department of Dermatology, Ehime University Graduate School of Medicine.

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August 2012

Interactions between myofibroblast differentiation and epidermogenesis in constructing human living skin equivalents.

J Dermatol Sci 2012 Jan 12;65(1):50-7. Epub 2011 Nov 12.

Department of Dermatology, Ehime University Graduate School of Medicine, Shitsukawa, Toon City, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2011.10.008DOI Listing
January 2012

Nuclear translocation of phosphorylated STAT3 regulates VEGF-A-induced lymphatic endothelial cell migration and tube formation.

Biochem Biophys Res Commun 2011 Sep 3;412(3):441-5. Epub 2011 Aug 3.

Department of Dermatology, Ehime University Graduate School of Medicine, Toon, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2011.07.111DOI Listing
September 2011

Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes.

J Allergy Clin Immunol 2011 Mar 26;127(3):806-14.e1-4. Epub 2011 Jan 26.

Department of Dermatology, Ehime University Graduate School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1016/j.jaci.2010.12.006DOI Listing
March 2011

New aspects of drug-induced hypersensitivity syndrome.

J Dermatol 2011 Mar;38(3):222-8

Department of Dermatology, Ehime University Graduate School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1111/j.1346-8138.2010.01176.xDOI Listing
March 2011

PPARγ mediates innate immunity by regulating the 1α,25-dihydroxyvitamin D3 induced hBD-3 and cathelicidin in human keratinocytes.

J Dermatol Sci 2010 Dec 23;60(3):179-86. Epub 2010 Oct 23.

Department of Dermatology, Ehime University School of Medicine, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2010.09.008DOI Listing
December 2010

Occupational trichloroethylene hypersensitivity syndrome with human herpesvirus-6 and cytomegalovirus reactivation.

Dermatology 2010 Aug 21;221(1):17-22. Epub 2010 Apr 21.

Department of Dermatology, Showa University School of Medicine, Tokyo, Japan.

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https://www.karger.com/Article/FullText/290775
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http://dx.doi.org/10.1159/000290775DOI Listing
August 2010

Living skin equivalents constructed using human amnions as a matrix.

J Dermatol Sci 2009 Dec 23;56(3):188-95. Epub 2009 Oct 23.

Department of Dermatology, Ehime University Graduate School of Medicine, Toon City, Ehime, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2009.09.009DOI Listing
December 2009

IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression.

Eur J Immunol 2009 Oct;39(10):2779-88

Department of Dermatology, Ehime University Graduate School of Medicine, Shitsukawa, Toon-city, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1002/eji.200939473DOI Listing
October 2009

[Drug-induced hypersensitivity syndrome and HHV-6 reactivation].

Uirusu 2009 Jun;59(1):23-30

Department of Dermatology, Ehime University Graduate School of Medicine.

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June 2009

Carbamazepine-induced drug-induced hypersensitivity syndrome in a 14-year-old Japanese boy.

Epilepsia 2008 Dec 17;49(12):2118-21. Epub 2008 Sep 17.

Department of Pediatrics, Ehime University Graduate School of Medicine, Toon, Ehime, Japan.

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http://dx.doi.org/10.1111/j.1528-1167.2008.01785.xDOI Listing
December 2008

The NF-kappaB, p38 MAPK and STAT1 pathways differentially regulate the dsRNA-mediated innate immune responses of epidermal keratinocytes.

Int Immunol 2008 Jul 19;20(7):901-9. Epub 2008 May 19.

Department of Dermatology, Ehime University Graduate School of Medicine, Toon-city, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1093/intimm/dxn048DOI Listing
July 2008

[Drug-induced hypersensitivity syndrome: DIHS].

Arerugi 2007 Nov;56(11):1346-50

Department of Dermatology, Ehime University Graduate School of Medicine.

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November 2007

[Drug-induced hypersensitivity syndrome].

Nihon Rinsho 2007 Oct;65 Suppl 8:341-3

Department of Dermatology, Ehime University Graduate School of Medicine.

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October 2007

CXCL16 is a novel mediator of the innate immunity of epidermal keratinocytes.

Int Immunol 2007 Sep;19(9):1095-102

Department of Dermatology, Ehime University School of Medicine, Shitsukawa, Toon-city, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1093/intimm/dxm083DOI Listing
September 2007

SOCS1-negative feedback of STAT1 activation is a key pathway in the dsRNA-induced innate immune response of human keratinocytes.

J Invest Dermatol 2006 Jul 20;126(7):1574-81. Epub 2006 Apr 20.

Department of Dermatology, Ehime University School of Medicine, Toon-city, Ehime, Japan.

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http://dx.doi.org/10.1038/sj.jid.5700294DOI Listing
July 2006

Bone morphogenetic protein-2 modulates Wnt and frizzled expression and enhances the canonical pathway of Wnt signaling in normal keratinocytes.

J Dermatol Sci 2006 May 24;42(2):111-9. Epub 2006 Jan 24.

Department of Dermatology, Ehime University School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2005.12.011DOI Listing
May 2006

Human herpesvirus 6 impairs differentiation of monocytes to dendritic cells.

Exp Hematol 2006 May;34(5):642-53

First Department of Internal Medicine, Ehime University School of Medicine Shitsukawa, Toon, Ehime, Japan.

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http://dx.doi.org/10.1016/j.exphem.2006.02.001DOI Listing
May 2006

[HHV-6 and drug-induced hypersensitivity syndrome].

Nihon Rinsho 2006 Mar;64 Suppl 3:476-9

Department of Dermatology, Ehime University School of Medicine.

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March 2006

Microbubble-enhanced ultrasound for gene transfer into living skin equivalents.

J Dermatol Sci 2005 Nov 18;40(2):105-14. Epub 2005 Aug 18.

Department of Dermatology, Ehime University School of Medicine, Shitsukawa, Toon, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2005.07.001DOI Listing
November 2005

dsRNA-mediated innate immunity of epidermal keratinocytes.

Biochem Biophys Res Commun 2005 Sep;335(2):505-11

Department of Dermatology, Ehime University School of Medicine, Shitsukawa, Toon-city, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2005.07.105DOI Listing
September 2005

A case of histopathologically typical toxic epidermal necrolysis despite no visible blisters or erosive lesions.

J Dermatol 2005 Aug;32(8):654-60

Division of Dermatology, Kinan Hospital, Mihama, Japan.

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August 2005

SOCS3/CIS3 negative regulation of STAT3 in HGF-induced keratinocyte migration.

Biochem Biophys Res Commun 2005 Feb;327(1):100-5

Department of Dermatology, Ehime University School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2004.11.145DOI Listing
February 2005

TGF-beta is not involved in early phase growth inhibition of keratinocytes by 1alpha,25(OH)2vitamin D3.

J Dermatol Sci 2004 Oct;36(1):41-50

Department of Dermatology, Ehime University School of Medicine, Onsengun, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2004.07.002DOI Listing
October 2004

Transcriptional downregulation of DC-SIGN in human herpesvirus 6-infected dendritic cells.

J Gen Virol 2004 Sep;85(Pt 9):2639-42

First Department of Internal Medicine and Department of Dermatology, Ehime University School of Medicine, Shigenobu, Ehime 791-0295, Japan.

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http://dx.doi.org/10.1099/vir.0.80095-0DOI Listing
September 2004

Human herpes virus 6 encephalitis in allopurinol-induced hypersensitivity syndrome.

Acta Derm Venereol 2003 ;83(2):128-31

Division of Dermatology, Clinical Molecular Medicine, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

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http://dx.doi.org/10.1080/00015550310007481DOI Listing
September 2003

Human herpesvirus 6 and drug allergy.

Curr Opin Allergy Clin Immunol 2003 Aug;3(4):255-60

Department of Dermatology, Ehime University School of Medicine, Ehime, Japan.

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http://dx.doi.org/10.1097/01.all.0000083949.99396.afDOI Listing
August 2003

Lack of evidence for TARC/CCL17 production by normal human keratinocytes in vitro.

J Dermatol Sci 2003 Feb;31(1):37-42

Department of Dermatology, Ehime University School of Medicine, Shitsukawa, Shigenobucho, Onsengun, Ehime 791-0295, Japan.

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February 2003

Differential effects of desmoglein 1 and desmoglein 3 on desmosome formation.

J Invest Dermatol 2002 Dec;119(6):1231-6

Department of Dermatology, School of Medicine, Ehime University, Ehime, Japan.

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http://dx.doi.org/10.1046/j.1523-1747.2002.19648.xDOI Listing
December 2002

Drug hypersensitivity syndrome and human herpesvirus 6 reactivation.

Arch Dermatol 2002 Feb;138(2):268-9

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February 2002