Publications by authors named "Mike E Robbins"

42Publications

Pathology of fractionated whole-brain irradiation in rhesus monkeys ( Macaca mulatta ).

Radiat Res 2015 Mar 17;183(3):367-74. Epub 2015 Feb 17.

a Department of Pathology/Comparative Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina.

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http://dx.doi.org/10.1667/RR13898.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467778PMC
March 2015

Impact of breathing 100% oxygen on radiation-induced cognitive impairment.

Radiat Res 2014 Nov 22;182(5):580-5. Epub 2014 Oct 22.

a  Department of Radiation Oncology, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157.

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http://dx.doi.org/10.1667/RR13643.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4321947PMC
November 2014

Differential activation of catalase expression and activity by PPAR agonists: implications for astrocyte protection in anti-glioma therapy.

Redox Biol 2013 26;1:70-9. Epub 2013 Jan 26.

Department of Radiation Oncology, Free Radical and Radiation Biology, Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA 52242, USA ; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1016/j.redox.2012.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757675PMC
May 2015

Angiotensin-(1-7) prevents radiation-induced inflammation in rat primary astrocytes through regulation of MAP kinase signaling.

Free Radic Biol Med 2013 Dec 3;65:1060-1068. Epub 2013 Sep 3.

Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA; Department of Radiation Oncology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA; Brain Tumor Center of Excellence, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2013.08.183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879043PMC
December 2013

The PPARδ agonist GW0742 inhibits neuroinflammation, but does not restore neurogenesis or prevent early delayed hippocampal-dependent cognitive impairment after whole-brain irradiation.

Free Radic Biol Med 2013 Aug 14;61:1-9. Epub 2013 Mar 14.

Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA; Brain Tumor Center of Excellence, Comprehensive Cancer Center, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA; Department of Radiation Oncology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2013.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884086PMC
August 2013

Molecular pathways: radiation-induced cognitive impairment.

Clin Cancer Res 2013 May 6;19(9):2294-300. Epub 2013 Feb 6.

Department of Radiation Oncology and Cancer Biology, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-2903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642233PMC
May 2013

Radiation-induced cognitive impairment--from bench to bedside.

Neuro Oncol 2012 Sep;14 Suppl 4:iv37-44

Department of Radiation Oncology, Brain Tumor Center of Excellence, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1093/neuonc/nos196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480242PMC
September 2012

Behavioral paradigms to evaluate PPAR modulation in animal models of brain injury.

Methods Mol Biol 2013 ;952:325-36

Departments of Radiation Oncology and Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC, USA.

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http://link.springer.com/10.1007/978-1-62703-155-4_24
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http://dx.doi.org/10.1007/978-1-62703-155-4_24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795415PMC
March 2013

Radiation-induced brain injury: A review.

Front Oncol 2012 19;2:73. Epub 2012 Jul 19.

Department of Radiation Oncology, Wake Forest School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.3389/fonc.2012.00073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400082PMC
August 2012

Chronic administration of the angiotensin-converting enzyme inhibitor, ramipril, prevents fractionated whole-brain irradiation-induced perirhinal cortex-dependent cognitive impairment.

Radiat Res 2012 Jul 12;178(1):46-56. Epub 2012 Jun 12.

Department of Molecular Medicine and Translational Science, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422865PMC
http://dx.doi.org/10.1667/rr2731.1DOI Listing
July 2012

Imaging radiation-induced normal tissue injury.

Radiat Res 2012 Apr 21;177(4):449-66. Epub 2012 Feb 21.

Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733443PMC
http://dx.doi.org/10.1667/rr2530.1DOI Listing
April 2012

Neuroprotective Mechanisms of PPARδ: Modulation of Oxidative Stress and Inflammatory Processes.

PPAR Res 2011 29;2011:373560. Epub 2011 Oct 29.

Department of Cancer Biology, Comprehensive Cancer Center, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1155/2011/373560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205692PMC
August 2012

Specific issues in small animal dosimetry and irradiator calibration.

Int J Radiat Biol 2011 Oct;87(10):1001-10

Department of Radiology, Duke University, Durham, NC 27157, USA.

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http://dx.doi.org/10.3109/09553002.2011.556178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646294PMC
October 2011

A model for assessing cognitive impairment after fractionated whole-brain irradiation in nonhuman primates.

Radiat Res 2011 Apr 28;175(4):519-25. Epub 2011 Jan 28.

Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

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http://www.bioone.org/doi/10.1667/RR2497.1
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http://dx.doi.org/10.1667/RR2497.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747826PMC
April 2011

Effects of the AT1 receptor antagonist L-158,809 on microglia and neurogenesis after fractionated whole-brain irradiation.

Radiat Res 2010 Jan;173(1):49-61

Program in Neuroscience, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1010, USA.

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http://www.bioone.org/doi/10.1667/RR1821.1
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http://dx.doi.org/10.1667/RR1821.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811039PMC
January 2010

The PPARalpha agonist fenofibrate preserves hippocampal neurogenesis and inhibits microglial activation after whole-brain irradiation.

Int J Radiat Oncol Biol Phys 2009 Nov;75(3):870-7

Department of Cancer Biology, Comprehensive Cancer Center, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2009.06.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2789462PMC
November 2009

Role of PPARs in Radiation-Induced Brain Injury.

PPAR Res 2010 17;2010:234975. Epub 2009 Sep 17.

Department of Cancer Biology, Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1155/2010/234975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748193PMC
July 2011

Inflammation and chronic oxidative stress in radiation-induced late normal tissue injury: therapeutic implications.

Curr Med Chem 2009 ;16(2):130-43

Department of Radiation Oncology and Brain Tumor Center of Excellence, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.2174/092986709787002790DOI Listing
March 2009

The AT1 receptor antagonist, L-158,809, prevents or ameliorates fractionated whole-brain irradiation-induced cognitive impairment.

Int J Radiat Oncol Biol Phys 2009 Feb 10;73(2):499-505. Epub 2008 Dec 10.

Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2008.09.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631653PMC
February 2009

PPARalpha ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-kappaB and AP-1 pathways.

Free Radic Biol Med 2008 Dec 17;45(12):1695-704. Epub 2008 Sep 17.

Department of Cancer Biology, Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2008.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648135PMC
December 2008

Decreasing peroxiredoxin II expression decreases glutathione, alters cell cycle distribution, and sensitizes glioma cells to ionizing radiation and H(2)O(2).

Free Radic Biol Med 2008 Oct 27;45(8):1178-89. Epub 2008 Jul 27.

Department of Radiation Oncology and Brain Tumor Center of Excellence, Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2008.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628750PMC
October 2008

NADPH oxidase mediates radiation-induced oxidative stress in rat brain microvascular endothelial cells.

Free Radic Biol Med 2008 Sep 30;45(6):929-38. Epub 2008 Jun 30.

Department of Radiation Oncology, and Brain Tumor Center of Excellence, Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2008.06.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2603423PMC
September 2008

Aging-dependent changes in the radiation response of the adult rat brain.

Int J Radiat Oncol Biol Phys 2008 Mar 31;70(3):826-34. Epub 2007 Dec 31.

Program in Neuroscience, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2007.10.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2268759PMC
March 2008

Quantitative in vivo proton MR spectroscopic evaluation of the irradiated rat brain.

J Magn Reson Imaging 2007 Dec;26(6):1590-5

MR Molecular Imaging Lab, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1059, USA.

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http://dx.doi.org/10.1002/jmri.21095DOI Listing
December 2007

Knocking out peroxisome proliferator-activated receptor (PPAR) alpha inhibits radiation-induced apoptosis in the mouse kidney through activation of NF-kappaB and increased expression of IAPs.

Radiat Res 2007 May;167(5):581-91

Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1667/RR0814.1DOI Listing
May 2007

Inhibiting catalase activity sensitizes 36B10 rat glioma cells to oxidative stress.

Free Radic Biol Med 2007 Mar 15;42(6):787-97. Epub 2006 Dec 15.

Section of Radiation Biology, Department of Radiation Oncology, and Brain Tumor Center of Excellence, Comprehensive Cancer Center, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.freeradbiomed.2006.11.032DOI Listing
March 2007

Administration of the peroxisomal proliferator-activated receptor gamma agonist pioglitazone during fractionated brain irradiation prevents radiation-induced cognitive impairment.

Int J Radiat Oncol Biol Phys 2007 Jan;67(1):6-9

Department of Radiation Oncology, Brain Tumor Center of Excellence, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2006.09.036DOI Listing
January 2007

Pathogenic role of the renin-angiotensin system in modulating radiation-induced late effects.

Int J Radiat Oncol Biol Phys 2006 Jan;64(1):6-12

Department of Radiation Oncology, Brain Tumor Center of Excellence, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2005.08.033DOI Listing
January 2006

The management of radiation-induced brain injury.

Cancer Treat Res 2006 ;128:7-22

Department of Radiation Oncology, Comprehensive Cancer Center of Wake Forest University School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1007/0-387-25354-8_2DOI Listing
February 2006

Radiation-induced up-regulation of Mmp2 involves increased mRNA stability, redox modulation, and MAPK activation.

Radiat Res 2004 Apr;161(4):418-29

Department of Radiation Oncology, Brain Tumor Center of Wake Forest University, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1667/3155DOI Listing
April 2004

Radiation nephropathy.

Semin Nephrol 2003 Sep;23(5):486-99

Medical College of Wisconsin, Milwaukee, WI, USA.

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http://dx.doi.org/10.1016/s0270-9295(03)00093-7DOI Listing
September 2003

Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter.

Mol Endocrinol 2002 Dec;16(12):2793-801

Free Radical and Radiation Biology Program, University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1210/me.2002-0020DOI Listing
December 2002

Radiation-induced kidney injury: a role for chronic oxidative stress?

Micron 2002 ;33(2):133-41

Free Radical and Radiation Biology Program, Department of Radiology, The University of Iowa, B-180 ML, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1016/s0968-4328(01)00006-3DOI Listing
January 2002