Mikael Huss

Mikael Huss

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Mikael Huss

Mikael Huss

Publications by authors named "Mikael Huss"

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Transcriptomes of Dravet syndrome iPSC derived GABAergic cells reveal dysregulated pathways for chromatin remodeling and neurodevelopment.

Neurobiol Dis 2019 Aug 21;132:104583. Epub 2019 Aug 21.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Biomedical Centre, Box 815, 751 08 Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.104583DOI Listing
August 2019

Identification of Salivary Microbiota and Its Association With Host Inflammatory Mediators in Periodontitis.

Front Cell Infect Microbiol 2019 21;9:216. Epub 2019 Jun 21.

Division of Periodontology, Department of Dental Medicine, Karolinska Institutet, Huddinge, Sweden.

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http://dx.doi.org/10.3389/fcimb.2019.00216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598052PMC
June 2019

A primer on deep learning in genomics.

Nat Genet 2019 01 26;51(1):12-18. Epub 2018 Nov 26.

Scripps Research Translational Institute, La Jolla, CA, USA.

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http://www.nature.com/articles/s41588-018-0295-5
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http://dx.doi.org/10.1038/s41588-018-0295-5DOI Listing
January 2019

Stationary and portable sequencing-based approaches for tracing wastewater contamination in urban stormwater systems.

Sci Rep 2018 08 9;8(1):11907. Epub 2018 Aug 9.

Science for Life Laboratory, Department of Gene Technology, School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41598-018-29920-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085348PMC
August 2018

Publisher Correction: Discovery of coding regions in the human genome by integrated proteogenomics analysis workflow.

Nat Commun 2018 05 8;9(1):1852. Epub 2018 May 8.

Department of Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Tomtebodavägen 23A, 171 65, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41467-018-04279-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940664PMC
May 2018

Discovery of coding regions in the human genome by integrated proteogenomics analysis workflow.

Nat Commun 2018 03 2;9(1):903. Epub 2018 Mar 2.

Department of Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Tomtebodavägen 23A, 171 65, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41467-018-03311-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834625PMC
March 2018

Erratum to: Identification of mutations, gene expression changes and fusion transcripts by whole transcriptome RNAseq in docetaxel resistant prostate cancer cells.

Springerplus 2016 8;5(1):2084. Epub 2016 Dec 8.

Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden ; Department of Clinical Oncology, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s40064-016-3759-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5143331PMC
December 2016

Identification of mutations, gene expression changes and fusion transcripts by whole transcriptome RNAseq in docetaxel resistant prostate cancer cells.

Springerplus 2016 24;5(1):1861. Epub 2016 Oct 24.

Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden ; Department of Clinical Oncology, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s40064-016-3543-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078122PMC
October 2016

Distinct transcription factor complexes act on a permissive chromatin landscape to establish regionalized gene expression in CNS stem cells.

Genome Res 2016 07 2;26(7):908-17. Epub 2016 May 2.

Ludwig Institute for Cancer Research, Karolinska Institutet, SE-171 77 Stockholm, Sweden; Department of Cell and Molecular Biology, Karolinska Institutet, SE-171 77 Stockholm, Sweden;

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http://dx.doi.org/10.1101/gr.203513.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937566PMC
July 2016

Cryptosporidium as a testbed for single cell genome characterization of unicellular eukaryotes.

BMC Genomics 2016 06 23;17:471. Epub 2016 Jun 23.

Department of Ecology and Genetics, Limnology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1186/s12864-016-2815-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4917956PMC
June 2016

The Human Gut Microbiome as a Transporter of Antibiotic Resistance Genes between Continents.

Antimicrob Agents Chemother 2015 Oct 10;59(10):6551-60. Epub 2015 Aug 10.

Laboratory for Molecular Infection Medicine Sweden, Department of Clinical Microbiology, Bacteriology, Umeå University, Umeå, Sweden

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http://dx.doi.org/10.1128/AAC.00933-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576037PMC
October 2015

Polymorphisms in DCDC2 and S100B associate with developmental dyslexia.

J Hum Genet 2015 Jul 16;60(7):399-401. Epub 2015 Apr 16.

1] Department of Biosciences and Nutrition, and Center for Innovative Medicine, Karolinska Institutet, Huddinge, Sweden [2] Science for Life Laboratory, Stockholm, Sweden [3] Molecular Neurology Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland [4] Folkhälsan Institute of Genetics, Helsinki, Finland.

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http://dx.doi.org/10.1038/jhg.2015.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4521290PMC
July 2015

Reprogramming of Yersinia from virulent to persistent mode revealed by complex in vivo RNA-seq analysis.

PLoS Pathog 2015 Jan 15;11(1):e1004600. Epub 2015 Jan 15.

Department of Molecular Biology, Umeå Centre for Microbial Research (UCMR), Umeå University, Umeå, Sweden; Department of Molecular Biology, Laboratory for Molecular Infection Medicine Sweden (MIMS), Umea University, Umeå, Sweden.

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http://dx.doi.org/10.1371/journal.ppat.1004600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295882PMC
January 2015

The human skeletal muscle transcriptome: sex differences, alternative splicing, and tissue homogeneity assessed with RNA sequencing.

FASEB J 2014 Oct 11;28(10):4571-81. Epub 2014 Jul 11.

Department of Physiology and Pharmacology, Karolinska Institutet, Solna, Sweden;

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http://dx.doi.org/10.1096/fj.14-255000DOI Listing
October 2014

Assessment of whole genome amplification for sequence capture and massively parallel sequencing.

PLoS One 2014 7;9(1):e84785. Epub 2014 Jan 7.

Science for Life Laboratory, School of Biotechnology, Division of Gene Technology, Royal Institute of Technology, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0084785PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883664PMC
September 2014

The network organization of cancer-associated protein complexes in human tissues.

Sci Rep 2013 ;3:1583

Department of Mathematics, Logistical Engineering University, Chongqing, China.

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http://dx.doi.org/10.1038/srep01583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620901PMC
June 2014

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

Authors:
Catherine A Brownstein Alan H Beggs Nils Homer Barry Merriman Timothy W Yu Katherine C Flannery Elizabeth T DeChene Meghan C Towne Sarah K Savage Emily N Price Ingrid A Holm Lovelace J Luquette Elaine Lyon Joseph Majzoub Peter Neupert David McCallie Peter Szolovits Huntington F Willard Nancy J Mendelsohn Renee Temme Richard S Finkel Sabrina W Yum Livija Medne Shamil R Sunyaev Ivan Adzhubey Christopher A Cassa Paul I W de Bakker Hatice Duzkale Piotr Dworzyński William Fairbrother Laurent Francioli Birgit H Funke Monica A Giovanni Robert E Handsaker Kasper Lage Matthew S Lebo Monkol Lek Ignaty Leshchiner Daniel G MacArthur Heather M McLaughlin Michael F Murray Tune H Pers Paz P Polak Soumya Raychaudhuri Heidi L Rehm Rachel Soemedi Nathan O Stitziel Sara Vestecka Jochen Supper Claudia Gugenmus Bernward Klocke Alexander Hahn Max Schubach Mortiz Menzel Saskia Biskup Peter Freisinger Mario Deng Martin Braun Sven Perner Richard J H Smith Janeen L Andorf Jian Huang Kelli Ryckman Val C Sheffield Edwin M Stone Thomas Bair E Ann Black-Ziegelbein Terry A Braun Benjamin Darbro Adam P DeLuca Diana L Kolbe Todd E Scheetz Aiden E Shearer Rama Sompallae Kai Wang Alexander G Bassuk Erik Edens Katherine Mathews Steven A Moore Oleg A Shchelochkov Pamela Trapane Aaron Bossler Colleen A Campbell Jonathan W Heusel Anne Kwitek Tara Maga Karin Panzer Thomas Wassink Douglas Van Daele Hela Azaiez Kevin Booth Nic Meyer Michael M Segal Marc S Williams Gerard Tromp Peter White Donald Corsmeier Sara Fitzgerald-Butt Gail Herman Devon Lamb-Thrush Kim L McBride David Newsom Christopher R Pierson Alexander T Rakowsky Aleš Maver Luca Lovrečić Anja Palandačić Borut Peterlin Ali Torkamani Anna Wedell Mikael Huss Andrey Alexeyenko Jessica M Lindvall Måns Magnusson Daniel Nilsson Henrik Stranneheim Fulya Taylan Christian Gilissen Alexander Hoischen Bregje van Bon Helger Yntema Marcel Nelen Weidong Zhang Jason Sager Lu Zhang Kathryn Blair Deniz Kural Michael Cariaso Greg G Lennon Asif Javed Saloni Agrawal Pauline C Ng Komal S Sandhu Shuba Krishna Vamsi Veeramachaneni Ofer Isakov Eran Halperin Eitan Friedman Noam Shomron Gustavo Glusman Jared C Roach Juan Caballero Hannah C Cox Denise Mauldin Seth A Ament Lee Rowen Daniel R Richards F Anthony San Lucas Manuel L Gonzalez-Garay C Thomas Caskey Yu Bai Ying Huang Fang Fang Yan Zhang Zhengyuan Wang Jorge Barrera Juan M Garcia-Lobo Domingo González-Lamuño Javier Llorca Maria C Rodriguez Ignacio Varela Martin G Reese Francisco M De La Vega Edward Kiruluta Michele Cargill Reece K Hart Jon M Sorenson Gholson J Lyon David A Stevenson Bruce E Bray Barry M Moore Karen Eilbeck Mark Yandell Hongyu Zhao Lin Hou Xiaowei Chen Xiting Yan Mengjie Chen Cong Li Can Yang Murat Gunel Peining Li Yong Kong Austin C Alexander Zayed I Albertyn Kym M Boycott Dennis E Bulman Paul M K Gordon A Micheil Innes Bartha M Knoppers Jacek Majewski Christian R Marshall Jillian S Parboosingh Sarah L Sawyer Mark E Samuels Jeremy Schwartzentruber Isaac S Kohane David M Margulies

Genome Biol 2014 Mar 25;15(3):R53. Epub 2014 Mar 25.

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http://dx.doi.org/10.1186/gb-2014-15-3-r53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073084PMC
March 2014

HiRIEF LC-MS enables deep proteome coverage and unbiased proteogenomics.

Nat Methods 2014 Jan 17;11(1):59-62. Epub 2013 Nov 17.

Department of Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden.

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http://www.nature.com/articles/nmeth.2732
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http://dx.doi.org/10.1038/nmeth.2732DOI Listing
January 2014

Evidence of a functional estrogen receptor in parathyroid adenomas.

J Clin Endocrinol Metab 2012 Dec 28;97(12):4631-9. Epub 2012 Sep 28.

Department of Molecular Medicine and Surgery, Karolinska University Hospital, Cancer Centrum Karolinska, R8:04, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1210/jc.2012-2484DOI Listing
December 2012

Validation of whole genome amplification for analysis of the p53 tumor suppressor gene in limited amounts of tumor samples.

Biochem Biophys Res Commun 2012 Aug 27;425(2):379-83. Epub 2012 Jul 27.

Science for Life Laboratory, School of Biotechnology, Division of Gene Technology, Royal Institute of Technology, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.bbrc.2012.07.101DOI Listing
August 2012

A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity.

Nature 2010 Nov 17;468(7321):316-20. Epub 2010 Oct 17.

Gene Regulation Laboratory, Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672.

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http://dx.doi.org/10.1038/nature09531DOI Listing
November 2010

Introduction into the analysis of high-throughput-sequencing based epigenome data.

Authors:
Mikael Huss

Brief Bioinform 2010 Sep 10;11(5):512-23. Epub 2010 May 10.

Genome Institute of Singapore.

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http://dx.doi.org/10.1093/bib/bbq014DOI Listing
September 2010

Q&A: ChIP-seq technologies and the study of gene regulation.

BMC Biol 2010 May 14;8:56. Epub 2010 May 14.

Genome Institute of Singapore, 60 Biopolis Street, Number 02-01, Genome, Singapore 138672.

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http://bmcbiol.biomedcentral.com/articles/10.1186/1741-7007-
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http://dx.doi.org/10.1186/1741-7007-8-56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871264PMC
May 2010

The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells.

Cell Stem Cell 2010 Feb 21;6(2):167-74. Epub 2010 Jan 21.

Gene Regulation Laboratory, Genome Institute of Singapore, Singapore 138672, Singapore.

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http://dx.doi.org/10.1016/j.stem.2009.12.009DOI Listing
February 2010

Simple cellular and network control principles govern complex patterns of motor behavior.

Proc Natl Acad Sci U S A 2009 Nov 9;106(47):20027-32. Epub 2009 Nov 9.

School of Computer Science and Communication, Royal Institute of Technology, AlbaNova University Center, S-106 91 Stockholm, Sweden.

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http://dx.doi.org/10.1073/pnas.0906722106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785286PMC
November 2009

An experimentally constrained computational model of NMDA oscillations in lamprey CPG neurons.

J Comput Neurosci 2008 Aug 15;25(1):108-21. Epub 2007 Dec 15.

School of Computer Science and Communication, Royal Institute of Technology, 100 44, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s10827-007-0067-1DOI Listing
August 2008

Comment on "Regularizing capacity of metabolic networks".

Phys Rev E Stat Nonlin Soft Matter Phys 2008 Feb 4;77(2 Pt 1):023901; discussion 023902. Epub 2008 Feb 4.

Department of Computer Science, University of New Mexico, Albuquerque, NM 87131, USA.

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http://dx.doi.org/10.1103/PhysRevE.77.023901DOI Listing
February 2008

Roles of ionic currents in lamprey CpG neurons: a modeling study.

J Neurophysiol 2007 Apr 7;97(4):2696-711. Epub 2007 Feb 7.

School of Computer Science and Communication, Royal Institute of Technology, Stockholm, Sweden.

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http://dx.doi.org/10.1152/jn.00528.2006DOI Listing
April 2007

Role-similarity based functional prediction in networked systems: application to the yeast proteome.

J R Soc Interface 2005 Sep;2(4):327-33

Department of Physics, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1098/rsif.2005.0046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1578265PMC
September 2005

Subnetwork hierarchies of biochemical pathways.

Bioinformatics 2003 Mar;19(4):532-8

Department of Theoretical Physics, Umea, 901 87 Umea, Sweden.

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http://dx.doi.org/10.1093/bioinformatics/btg033DOI Listing
March 2003