Mihai G Netea

Mihai G Netea

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Mihai G Netea

Publications by authors named "Mihai G Netea"

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Differential effects of BCG vaccine on immune responses induced by vi polysaccharide typhoid fever vaccination: an explorative randomized trial.

Eur J Clin Microbiol Infect Dis 2020 Jun 17;39(6):1177-1184. Epub 2020 Feb 17.

Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, 6526, GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10096-020-03813-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225183PMC
June 2020

BCG-induced trained immunity: can it offer protection against COVID-19?

Nat Rev Immunol 2020 Jun;20(6):335-337

School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1038/s41577-020-0337-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212510PMC
June 2020

Borrelia burgdorferi hijacks cellular metabolism of immune cells: Consequences for host defense.

Ticks Tick Borne Dis 2020 May 3;11(3):101386. Epub 2020 Feb 3.

Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ttbdis.2020.101386DOI Listing
May 2020

Trained Immunity: Linking Obesity and Cardiovascular Disease across the Life-Course?

Trends Endocrinol Metab 2020 May 8;31(5):378-389. Epub 2020 Feb 8.

Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia; Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2020.01.008DOI Listing
May 2020

Considering BCG vaccination to reduce the impact of COVID-19.

Lancet 2020 05 30;395(10236):1545-1546. Epub 2020 Apr 30.

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands; Immunology and Metabolism, Life & Medical Sciences Institute, University of Bonn, Bonn, Germany.

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http://dx.doi.org/10.1016/S0140-6736(20)31025-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252177PMC
May 2020

β-Glucan Induces Protective Trained Immunity against Mycobacterium tuberculosis Infection: A Key Role for IL-1.

Cell Rep 2020 May;31(7):107634

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242907PMC
May 2020

Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection.

Cell 2020 05 4;181(5):969-977. Epub 2020 May 4.

Department of Medical Microbiology, University Medical Center Utrecht, University of Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.cell.2020.04.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196902PMC
May 2020

Acromegaly, inflammation and cardiovascular disease: a review.

Rev Endocr Metab Disord 2020 May 26. Epub 2020 May 26.

Department of Internal Medicine, Radboud University Medical Center Nijmegen, Geert Grooteplein Zuid 10, 6525, GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s11154-020-09560-xDOI Listing
May 2020

Sex-Specific Regulation of Inflammation and Metabolic Syndrome in Obesity.

Arterioscler Thromb Vasc Biol 2020 May 28:ATVBAHA120314508. Epub 2020 May 28.

From the Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands (R.t.H., I.C.L.v.d.M., K.S., R.A.-G., M.J., S.P.S., T.B., H.L., H.D., J.d.G., L.A.B.J., J.H.W.R., M.G.H., N.P.R.).

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http://dx.doi.org/10.1161/ATVBAHA.120.314508DOI Listing
May 2020

Roles of trained immunity in the pathogenesis of cholangiopathies: a novel therapeutic target.

Hepatology 2020 May 28. Epub 2020 May 28.

Jiangsu Key Laboratory of Immunity and Metabolism, Department of Pathogenic Biology and Immunology, Laboratory of Infection and Immunity, Xuzhou Medical University, Xuzhou, People's Republic of China.

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http://dx.doi.org/10.1002/hep.31395DOI Listing
May 2020

A Potential Role for Epigenetically Mediated Trained Immunity in Food Allergy.

iScience 2020 May 17;23(6):101171. Epub 2020 May 17.

Murdoch Children's Research Institute, and Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Flemington Road, Parkville, VIC 3052, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2020.101171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262566PMC
May 2020

Advances in understanding molecular regulation of innate immune memory.

Curr Opin Cell Biol 2020 Apr 25;63:68-75. Epub 2020 Jan 25.

Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, 6500HB, Nijmegen, the Netherlands; Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, 6525, GA, Nijmegen, the Netherlands; Department for Immunology & Metabolism, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.

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http://dx.doi.org/10.1016/j.ceb.2019.12.006DOI Listing
April 2020

New live attenuated tuberculosis vaccine MTBVAC induces trained immunity and confers protection against experimental lethal pneumonia.

PLoS Pathog 2020 Apr 2;16(4):e1008404. Epub 2020 Apr 2.

Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1371/journal.ppat.1008404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117655PMC
April 2020

Integrating GWAS with bulk and single-cell RNA-sequencing reveals a role for LY86 in the anti-Candida host response.

PLoS Pathog 2020 Apr 6;16(4):e1008408. Epub 2020 Apr 6.

Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1371/journal.ppat.1008408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7173933PMC
April 2020

Involvement of Lactate and Pyruvate in the Anti-Inflammatory Effects Exerted by Voluntary Activation of the Sympathetic Nervous System.

Metabolites 2020 Apr 10;10(4). Epub 2020 Apr 10.

Department of Intensive Care Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Internal Mail 710 Geert Grooteplein 10, 6500HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.3390/metabo10040148DOI Listing
April 2020

Early Clearance of Mycobacterium tuberculosis: The INFECT Case Contact Cohort Study in Indonesia.

J Infect Dis 2020 Mar;221(8):1351-1360

Centre for International Health, Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand.

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http://dx.doi.org/10.1093/infdis/jiz168DOI Listing
March 2020

The role of Toll-like receptor 10 in modulation of trained immunity.

Immunology 2020 03 26;159(3):289-297. Epub 2019 Nov 26.

Department of Internal Medicine, Radboud Center for Infectious Diseases (RCI), Radboud Institute of Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/imm.13145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011636PMC
March 2020

A joint effort: The interplay between the innate and the adaptive immune system in Lyme arthritis.

Immunol Rev 2020 03 13;294(1):63-79. Epub 2020 Jan 13.

Department of Internal Medicine, Radboud Center for Infectious Diseases (RCI), Radboud Institute of Molecular Life Sciences (RIMLS), Radboud Institute of Health Sciences (RIHS), Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/imr.12837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065069PMC
March 2020

Contribution of Genetic and Clinical Risk Factors to Development of Candidemia in Patients Receiving Home Parenteral Nutrition.

JPEN J Parenter Enteral Nutr 2020 Feb 10;44(2):282-290. Epub 2019 May 10.

Intestinal Failure Unit, Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1002/jpen.1604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065185PMC
February 2020

Aldosterone induces trained immunity: the role of fatty acid synthesis.

Cardiovasc Res 2020 Feb;116(2):317-328

Department of Internal Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 8, 6525 GA, Nijmegen, The Netherlands.

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https://academic.oup.com/cardiovascres/advance-article/doi/1
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http://dx.doi.org/10.1093/cvr/cvz137DOI Listing
February 2020

Lesion size is associated with genetic polymorphisms in TLR1, TLR6, and TIRAP genes in patients with major abscesses and diabetic foot infections.

Eur J Clin Microbiol Infect Dis 2020 Feb 30;39(2):353-360. Epub 2019 Nov 30.

Faculty of Medicine and Life Sciences, Research Group of Immunology and Biochemistry, Hasselt University, Hasselt, Belgium.

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http://dx.doi.org/10.1007/s10096-019-03732-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010613PMC
February 2020

Licensed Bacille Calmette-Guérin (BCG) formulations differ markedly in bacterial viability, RNA content and innate immune activation.

Vaccine 2020 Feb 28;38(9):2229-2240. Epub 2020 Jan 28.

Precision Vaccines Program, Division of Infectious Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT & Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2019.11.060DOI Listing
February 2020

Biomarkers of inflammation and the etiology of sepsis.

Biochem Soc Trans 2020 02;48(1):1-14

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1042/BST20190029DOI Listing
February 2020

Interacting, Nonspecific, Immunological Effects of Bacille Calmette-Guérin and Tetanus-diphtheria-pertussis Inactivated Polio Vaccinations: An Explorative, Randomized Trial.

Clin Infect Dis 2020 Jan;70(3):455-463

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/cid/ciz246DOI Listing
January 2020

Trained immunity in organ transplantation.

Am J Transplant 2020 01 28;20(1):10-18. Epub 2019 Oct 28.

Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1111/ajt.15620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940521PMC
January 2020

Recurrent Vulvovaginal Candidiasis: An Immunological Perspective.

Microorganisms 2020 Jan 21;8(2). Epub 2020 Jan 21.

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.3390/microorganisms8020144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074770PMC
January 2020

Immune recognition of putative alien microbial structures: Host-pathogen interactions in the age of space travel.

PLoS Pathog 2020 01 30;16(1):e1008153. Epub 2020 Jan 30.

Department of Laboratory Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1371/journal.ppat.1008153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6991955PMC
January 2020

Current gaps in sepsis immunology: new opportunities for translational research.

Lancet Infect Dis 2019 12 17;19(12):e422-e436. Epub 2019 Oct 17.

Hospital Universitario Río Hortega, Valladolid, Spain; Group for Biomedical Research in Sepsis, Instituto de Investigación Biomédica de Salamanca, Salamanca, Spain; Centro de Investigación Biomedica En Red-Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(19)30567-5DOI Listing
December 2019

Impact of Historic Migrations and Evolutionary Processes on Human Immunity.

Trends Immunol 2019 12 27;40(12):1105-1119. Epub 2019 Nov 27.

Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, 6500HB Nijmegen, The Netherlands; Department for Genomics and Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany; Human Genomics Laboratory, Craiova University of Medicine and Pharmacy, Craiova, Romania.

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http://dx.doi.org/10.1016/j.it.2019.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106516PMC
December 2019

Deletion of haematopoietic Dectin-2 or CARD9 does not protect from atherosclerosis development under hyperglycaemic conditions.

Diab Vasc Dis Res 2020 Jan-Feb;17(1):1479164119892140. Epub 2019 Dec 23.

Department of Internal Medicine and Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1177/1479164119892140DOI Listing
December 2019

Trained immunity confers broad-spectrum protection against bacterial infections.

J Infect Dis 2019 Dec 31. Epub 2019 Dec 31.

Infectious Diseases Service, Department of Medicine, Lausanne University Hospital and University of Lausanne, Epalinges, Switzerland.

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http://dx.doi.org/10.1093/infdis/jiz692DOI Listing
December 2019

Bromodomain inhibitor I-BET151 suppresses immune responses during fungal-immune interaction.

Eur J Immunol 2019 11 21;49(11):2044-2050. Epub 2019 Jun 21.

Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, 6500HB, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1002/eji.201848081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899658PMC
November 2019

Sixteen-Week Physical Activity Intervention in Subjects With Increased Cardiometabolic Risk Shifts Innate Immune Function Towards a Less Proinflammatory State.

J Am Heart Assoc 2019 11 18;8(21):e013764. Epub 2019 Oct 18.

Department of Internal Medicine Radboud Institute for Molecular Life Sciences (RIMLS) Radboud University Medical Center Nijmegen The Netherlands.

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http://dx.doi.org/10.1161/JAHA.119.013764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898840PMC
November 2019

Hard to Remember: Long-Term Functional Defects in Myeloid Cells and Wound Repair After Sepsis.

Authors:
Mihai G Netea

Arterioscler Thromb Vasc Biol 2019 11 23;39(11):2205-2206. Epub 2019 Oct 23.

From the Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen Medical Centre, The Netherlands (M.G.N.).

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http://dx.doi.org/10.1161/ATVBAHA.119.313281DOI Listing
November 2019

BCG vaccination is associated with reduced malaria prevalence in children under the age of 5 years in sub-Saharan Africa.

BMJ Glob Health 2019 14;4(6):e001862. Epub 2019 Nov 14.

Department of Internal Medicine, Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1136/bmjgh-2019-001862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861070PMC
November 2019

Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration.

Cell Oncol (Dordr) 2019 Oct 14;42(5):691-703. Epub 2019 Jun 14.

Department of Internal Medicine (463), Division of Endocrinology, Radboud University Medical Center, Geert Grooteplein Zuid 8, 6525, GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s13402-019-00457-9DOI Listing
October 2019

Targeting innate immunity for tuberculosis vaccination.

J Clin Invest 2019 09;129(9):3482-3491

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.1172/JCI128877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715374PMC
September 2019

β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32.

Cell Rep 2019 Sep;28(10):2659-2672.e6

Radboud Institute for Molecular Sciences (RILMS), Department of Internal Medicine and Radboud Center of Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, the Netherlands; Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Goiás, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.08.004DOI Listing
September 2019

Functional Annotation of Genetic Loci Associated With Sepsis Prioritizes Immune and Endothelial Cell Pathways.

Front Immunol 2019 14;10:1949. Epub 2019 Aug 14.

University of Groningen, University Medical Center Groningen, Genetics Department, Groningen, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2019.01949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6703137PMC
August 2019

Therapeutic targeting of trained immunity.

Nat Rev Drug Discov 2019 07;18(7):553-566

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.1038/s41573-019-0025-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069501PMC
July 2019

A possible link between recurrent upper respiratory tract infections and lower cytokine production in patients with Q fever fatigue syndrome.

Eur J Immunol 2019 07 9;49(7):1015-1022. Epub 2019 May 9.

Radboud Expertise Center for Q fever, Department of Internal Medicine, Division of Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/eji.20184801
Publisher Site
http://dx.doi.org/10.1002/eji.201848012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163623PMC
July 2019

Immunometabolism orchestrates training of innate immunity in atherosclerosis.

Cardiovasc Res 2019 07;115(9):1416-1424

Department of Internal Medicine, Radboud University Medical Center Nijmegen, Geert Grooteplein Zuid 8, GA, HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvz107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910162PMC
July 2019

Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia.

Cell Metab 2019 07 13;30(1):1-2. Epub 2019 Jun 13.

Department of Internal Medicine, and Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen 6525GA, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.05.014DOI Listing
July 2019

Predicting bacterial infection outcomes using single cell RNA-sequencing analysis of human immune cells.

Nat Commun 2019 07 22;10(1):3266. Epub 2019 Jul 22.

Department of Biological Regulation, Weizmann Institute of Science, 7610001, Rehovot, Israel.

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http://dx.doi.org/10.1038/s41467-019-11257-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646406PMC
July 2019

Immune memory characteristics of innate lymphoid cells.

Curr Opin Infect Dis 2019 06;32(3):196-203

Department for Immunology & Metabolism, Life and Medical Sciences Institute (LIMES).

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http://dx.doi.org/10.1097/QCO.0000000000000540DOI Listing
June 2019

The influence of neonatal Bacille Calmette-Guérin (BCG) immunisation on heterologous vaccine responses in infants.

Vaccine 2019 06 29;37(28):3735-3744. Epub 2019 May 29.

Department of Paediatrics, The University of Melbourne, Parkville, Australia; Infectious Diseases Research Group, Murdoch Children's Research Institute, Parkville, Australia; Infectious Diseases Unit, The Royal Children's Hospital Melbourne, Parkville, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2019.03.016DOI Listing
June 2019

Metabolic Adaptation Sets the Fate of Regulatory Macrophages.

Cell Metab 2019 06;29(6):1240-1242

Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein Zuid 8, 6525GA Nijmegen, the Netherlands; Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131193025
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http://dx.doi.org/10.1016/j.cmet.2019.05.012DOI Listing
June 2019

Itaconate as an immune modulator.

Aging (Albany NY) 2019 06;11(12):3898-3899

Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, 6500HB Nijmegen, the Netherlands.

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http://dx.doi.org/10.18632/aging.102057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629002PMC
June 2019

Effect of PTEN inactivating germline mutations on innate immune cell function and thyroid cancer-induced macrophages in patients with PTEN hamartoma tumor syndrome.

Oncogene 2019 05 22;38(19):3743-3755. Epub 2019 Jan 22.

Department of Internal Medicine, Division of Endocrinology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41388-019-0685-xDOI Listing
May 2019

Cytokine profiles in patients with Q fever fatigue syndrome.

J Infect 2019 05 23;78(5):349-357. Epub 2019 Jan 23.

Radboud Expertise Center for Q Fever, Department of Internal Medicine, Division of Infectious Diseases, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, the Netherlands; Department of Internal Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, the Netherlands; Radboud Center for Infectious Diseases, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2019.01.006DOI Listing
May 2019

Predictive value of ex-vivo drug-inhibited cytokine production for clinical response to biologic DMARD therapy in rheumatoid arthritis.

Clin Exp Rheumatol 2019 May-Jun;37(3):367-372. Epub 2019 Feb 7.

Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, the Netherlands.

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May 2019

A possible role for mitochondrial-derived peptides humanin and MOTS-c in patients with Q fever fatigue syndrome and chronic fatigue syndrome.

J Transl Med 2019 05 14;17(1):157. Epub 2019 May 14.

Radboud Expertise Center for Q Fever, Department of Internal Medicine, Division of Infectious Diseases 463, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12967-019-1906-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518812PMC
May 2019

Association of hemoglobin A1C with circulating metabolites in Dutch with European, African Surinamese and Ghanaian background.

Nutr Diabetes 2019 04 30;9(1):15. Epub 2019 Apr 30.

Clinical Epidemiology, Biostatistics, and Bioinformatics, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41387-019-0082-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491479PMC
April 2019

Opposite effects of Vaccinia and modified Vaccinia Ankara on trained immunity.

Eur J Clin Microbiol Infect Dis 2019 Mar 5;38(3):449-456. Epub 2019 Feb 5.

Department of Internal Medicine, Radboud University Medical Centre, Geert Grooteplein-Zuid 10, 6525GA, Nijmegen, The Netherlands.

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http://link.springer.com/10.1007/s10096-018-03449-z
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http://dx.doi.org/10.1007/s10096-018-03449-zDOI Listing
March 2019

Innate and Adaptive Immune Memory: an Evolutionary Continuum in the Host's Response to Pathogens.

Cell Host Microbe 2019 01;25(1):13-26

Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, 53115 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.12.006DOI Listing
January 2019

The fecal and mucosal microbiome in acute appendicitis patients: an observational study.

Future Microbiol 2019 01 21;14:111-127. Epub 2019 Jan 21.

Department of Infectious Diseases & Immunity, Jessa Hospital, Hasselt, Belgium.

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http://dx.doi.org/10.2217/fmb-2018-0203DOI Listing
January 2019

Trained Immunity Characteristics Are Associated With Progressive Cerebral Small Vessel Disease.

Stroke 2018 12;49(12):2910-2917

From the Department of Internal Medicine, Radboud University Medical Center Behaviour, (M.P.N., L.A.B.J., M.G.N., N.P.R.), Nijmegen, the Netherlands.

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http://dx.doi.org/10.1161/STROKEAHA.118.023192DOI Listing
December 2018