Mihai G Netea

Mihai G Netea

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Mihai G Netea

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Immune memory characteristics of innate lymphoid cells.

Curr Opin Infect Dis 2019 Jun;32(3):196-203

Department for Immunology & Metabolism, Life and Medical Sciences Institute (LIMES).

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http://dx.doi.org/10.1097/QCO.0000000000000540DOI Listing
June 2019

Effect of PTEN inactivating germline mutations on innate immune cell function and thyroid cancer-induced macrophages in patients with PTEN hamartoma tumor syndrome.

Oncogene 2019 May 22;38(19):3743-3755. Epub 2019 Jan 22.

Department of Internal Medicine, Division of Endocrinology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41388-019-0685-xDOI Listing
May 2019

Cytokine profiles in patients with Q fever fatigue syndrome.

J Infect 2019 May 23;78(5):349-357. Epub 2019 Jan 23.

Radboud Expertise Center for Q Fever, Department of Internal Medicine, Division of Infectious Diseases, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, the Netherlands; Department of Internal Medicine, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, the Netherlands; Radboud Center for Infectious Diseases, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2019.01.006DOI Listing
May 2019

Immunometabolism orchestrates training of innate immunity in atherosclerosis.

Cardiovasc Res 2019 May 3. Epub 2019 May 3.

Department of Internal Medicine, Radboud University Medical Center Nijmegen, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvz107DOI Listing
May 2019

Nonspecific effects of BCG vaccine on viral infections.

Clin Microbiol Infect 2019 May 2. Epub 2019 May 2.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.

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http://dx.doi.org/10.1016/j.cmi.2019.04.020DOI Listing
May 2019

Contribution of Genetic and Clinical Risk Factors to Development of Candidemia in Patients Receiving Home Parenteral Nutrition.

JPEN J Parenter Enteral Nutr 2019 May 10. Epub 2019 May 10.

Intestinal Failure Unit, Department of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.1002/jpen.1604DOI Listing
May 2019

A possible role for mitochondrial-derived peptides humanin and MOTS-c in patients with Q fever fatigue syndrome and chronic fatigue syndrome.

J Transl Med 2019 May 14;17(1):157. Epub 2019 May 14.

Radboud Expertise Center for Q Fever, Department of Internal Medicine, Division of Infectious Diseases 463, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12967-019-1906-3DOI Listing
May 2019

Role of Glutamine Metabolism in Host Defense Against Mycobacterium tuberculosis Infection.

J Infect Dis 2019 Apr;219(10):1662-1670

Department of Internal Medicine, Radboud University Medical Center, Nijmegen.

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http://dx.doi.org/10.1093/infdis/jiy709DOI Listing
April 2019

Therapeutic targeting of trained immunity.

Nat Rev Drug Discov 2019 Apr 9. Epub 2019 Apr 9.

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.1038/s41573-019-0025-4DOI Listing
April 2019

A possible link between recurrent upper respiratory tract infections and lower cytokine production in patients with Q fever fatigue syndrome.

Eur J Immunol 2019 Apr 18. Epub 2019 Apr 18.

Radboud Expertise Center for Q fever, Department of Internal Medicine, Division of Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/eji.20184801
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http://dx.doi.org/10.1002/eji.201848012DOI Listing
April 2019

Association of hemoglobin A1C with circulating metabolites in Dutch with European, African Surinamese and Ghanaian background.

Nutr Diabetes 2019 Apr 30;9(1):15. Epub 2019 Apr 30.

Clinical Epidemiology, Biostatistics, and Bioinformatics, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41387-019-0082-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491479PMC
April 2019

The Potential Role of Trained Immunity in Autoimmune and Autoinflammatory Disorders.

Front Immunol 2018 20;9:298. Epub 2018 Feb 20.

Department of Internal Medicine, Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2018.00298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826224PMC
March 2019

T-Cell Lymphopenia in Patients with Advanced Thyroid Carcinoma Is Associated with Poor Prognosis.

Oncologist 2019 Mar 3;24(3):e106-e110. Epub 2019 Jan 3.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

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http://theoncologist.alphamedpress.org/lookup/doi/10.1634/th
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http://dx.doi.org/10.1634/theoncologist.2018-0422DOI Listing
March 2019

Opposite effects of Vaccinia and modified Vaccinia Ankara on trained immunity.

Eur J Clin Microbiol Infect Dis 2019 Mar 5;38(3):449-456. Epub 2019 Feb 5.

Department of Internal Medicine, Radboud University Medical Centre, Geert Grooteplein-Zuid 10, 6525GA, Nijmegen, The Netherlands.

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http://link.springer.com/10.1007/s10096-018-03449-z
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http://dx.doi.org/10.1007/s10096-018-03449-zDOI Listing
March 2019

INTERACTING NON-SPECIFIC IMMUNOLOGICAL EFFECTS OF BCG AND Tdapf VACCINATIONS: AN EXPLORATIVE RANDOMIZED TRIAL.

Clin Infect Dis 2019 03 28. Epub 2019 Mar 28.

Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/cid/ciz246DOI Listing
March 2019

Long-term reprogramming of the innate immune system.

J Leukoc Biol 2019 Feb 12;105(2):329-338. Epub 2018 Jul 12.

Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://doi.wiley.com/10.1002/JLB.MR0318-104R
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http://dx.doi.org/10.1002/JLB.MR0318-104RDOI Listing
February 2019

Induction of innate immune memory: the role of cellular metabolism.

Curr Opin Immunol 2019 Feb 19;56:10-16. Epub 2018 Sep 19.

Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein Zuid 8, 6525GA Nijmegen, The Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany; Human Genomics Laboratory, Craiova University of Medicine and Pharmacy, Craiova, Romania. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2018.09.001DOI Listing
February 2019

PTEN Hamartoma Tumor Syndrome and Immune Dysregulation.

Transl Oncol 2019 Feb 30;12(2):361-367. Epub 2018 Nov 30.

Department of Human Genetics, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525, GA, Nijmegen, The Netherlands; Radboud Institute for Molecular Life Sciences, Geert Grooteplein Zuid 28, 6525, GA, Nijmegen, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19365233183047
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http://dx.doi.org/10.1016/j.tranon.2018.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277246PMC
February 2019

Predictive value of ex-vivo drug-inhibited cytokine production for clinical response to biologic DMARD therapy in rheumatoid arthritis.

Clin Exp Rheumatol 2019 Feb 7. Epub 2019 Feb 7.

Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, the Netherlands.

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February 2019

The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.

Cell Metab 2019 Jan 4;29(1):211-220.e5. Epub 2018 Oct 4.

Department of Internal Medicine (463) and Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen 6500 HB, the Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany; Human Genomics Laboratory, Craiova University of Medicine and Pharmacy, Craiova, Romania.

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https://linkinghub.elsevier.com/retrieve/pii/S15504131183056
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http://dx.doi.org/10.1016/j.cmet.2018.09.003DOI Listing
January 2019

Innate and Adaptive Immune Memory: an Evolutionary Continuum in the Host's Response to Pathogens.

Cell Host Microbe 2019 01;25(1):13-26

Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany; PRECISE Platform for Single Cell Genomics and Epigenomics at the German Center for Neurodegenerative Diseases and the University of Bonn, 53115 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.12.006DOI Listing
January 2019

The fecal and mucosal microbiome in acute appendicitis patients: an observational study.

Future Microbiol 2019 01 21;14:111-127. Epub 2019 Jan 21.

Department of Infectious Diseases & Immunity, Jessa Hospital, Hasselt, Belgium.

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http://dx.doi.org/10.2217/fmb-2018-0203DOI Listing
January 2019

Firing Up Glycolysis: BCG Vaccination Effects on Type 1 Diabetes Mellitus.

Trends Endocrinol Metab 2018 12 13;29(12):813-814. Epub 2018 Oct 13.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Department for Genomics and Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10432760183016
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http://dx.doi.org/10.1016/j.tem.2018.10.001DOI Listing
December 2018

Trained Immunity Characteristics Are Associated With Progressive Cerebral Small Vessel Disease.

Stroke 2018 Dec;49(12):2910-2917

From the Department of Internal Medicine, Radboud University Medical Center Behaviour, (M.P.N., L.A.B.J., M.G.N., N.P.R.), Nijmegen, the Netherlands.

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http://dx.doi.org/10.1161/STROKEAHA.118.023192DOI Listing
December 2018

H4:IC31 Vaccine or BCG Revaccination for Tuberculosis.

N Engl J Med 2018 11;379(20):1969

Radboud University Medical Center, Nijmegen, the Netherlands

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http://www.nejm.org/doi/10.1056/NEJMc1811046
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http://dx.doi.org/10.1056/NEJMc1811046DOI Listing
November 2018

Trained Immunity and Local Innate Immune Memory in the Lung.

Cell 2018 Nov;175(6):1463-1465

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183149
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http://dx.doi.org/10.1016/j.cell.2018.11.007DOI Listing
November 2018

The causes and consequences of variation in human cytokine production in health.

Curr Opin Immunol 2018 10 15;54:50-58. Epub 2018 Jun 15.

The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Boston, MA 02114, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2018.05.012DOI Listing
October 2018

Non-specific effects of vaccines: Current evidence and potential implications.

Semin Immunol 2018 10 11;39:35-43. Epub 2018 Jul 11.

Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.smim.2018.06.002DOI Listing
October 2018

The impact of sex hormones on BCG-induced trained immunity.

J Leukoc Biol 2018 09;104(3):573-578

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/JLB.5MA0118-027RDOI Listing
September 2018

T Cell Metabolism Has Evolved to Tolerate Tuberculosis.

Cell Metab 2018 Sep;28(3):332-333

Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, the Netherlands; Department of Genomics and Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.08.015DOI Listing
September 2018

The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis.

Cell Host Microbe 2018 09;24(3):364-378.e6

Lineberger Comprehensive Cancer Center, UNC-Chapel Hill, Chapel Hill, NC, USA; Department of Genetics, UNC-Chapel Hill, Chapel Hill, NC, USA; Department of Microbiology and Immunology, UNC-Chapel Hill, Chapel Hill, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161752PMC
September 2018

Be aware, innate immune cells remember.

Aging (Albany NY) 2018 Sep;10(9):2218-2219

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.18632/aging.101552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188483PMC
September 2018

Genetic variant in IL-32 is associated with the ex vivo cytokine production of anti-TNF treated PBMCs from rheumatoid arthritis patients.

Sci Rep 2018 Sep 19;8(1):14050. Epub 2018 Sep 19.

Department of Internal Medicine, Radboud Centre for Infectious Diseases (RCI) and Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-018-32485-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145899PMC
September 2018

Getting to the marrow of trained immunity.

Epigenomics 2018 09;10(9):1151-1154

Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.2217/epi-2018-0098DOI Listing
September 2018

Induction of Trained Innate Immunity in Human Monocytes by Bovine Milk and Milk-Derived Immunoglobulin G.

Nutrients 2018 Sep 27;10(10). Epub 2018 Sep 27.

Cell Biology and Immunology, Wageningen University, Wageningen, P.O. Box 338, 6708 WD Wageningen, The Netherlands.

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http://dx.doi.org/10.3390/nu10101378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213000PMC
September 2018

A role for TLR10 in obesity and adipose tissue morphology.

Cytokine 2018 08 23;108:205-212. Epub 2018 Apr 23.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Nutrition, Metabolism and Genomics Group, Division of Human Nutrition, Wageningen University, Wageningen, The Netherlands.

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http://dx.doi.org/10.1016/j.cyto.2018.03.021DOI Listing
August 2018

Trained immunity as a novel therapeutic strategy.

Curr Opin Pharmacol 2018 08 24;41:52-58. Epub 2018 Apr 24.

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.coph.2018.04.007DOI Listing
August 2018

Intracellular Alarmins: Hidden dangers signals crucial for cancer, host defense and inflammatory processes.

Semin Immunol 2018 08 26;38:1-2. Epub 2018 Oct 26.

Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Medical Center, 6525GA Nijmegen, the Netherlands; Human Genomics Laboratory, Craiova University of Medicine and Pharmacy, 200349 Craiova, Romania; Department for Immunology & Metabolism, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.

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http://dx.doi.org/10.1016/j.smim.2018.10.007DOI Listing
August 2018

Female-Specific Association Between Variants on Chromosome 9 and Self-Reported Diagnosis of Irritable Bowel Syndrome.

Gastroenterology 2018 07 5;155(1):168-179. Epub 2018 Apr 5.

Unit of Gastrointestinal Genetics, Department of Gastrointestinal and Liver Diseases, Biodonostia Health Research Institute, San Sebastián, Spain; Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden; Unit of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden; Ikerbasque, Basque Science Foundation, Bilbao, Spain. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183040
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http://dx.doi.org/10.1053/j.gastro.2018.03.064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035117PMC
July 2018

Environmental Signals Influencing Myeloid Cell Metabolism and Function in Diabetes.

Trends Endocrinol Metab 2018 07 19;29(7):468-480. Epub 2018 May 19.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands; Nutrition, Metabolism and Genomics Group, Division of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2018.04.008DOI Listing
July 2018

Interferon-γ and CXCL10 responses related to complaints in patients with Q fever fatigue syndrome.

Eur J Clin Microbiol Infect Dis 2018 Jul 26;37(7):1385-1391. Epub 2018 May 26.

Radboud Expertise Center for Q fever, Department of Internal Medicine, Division of Infectious Diseases 463, Radboud University Medical Center, P.O. Box 9101, 6500, HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10096-018-3265-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015096PMC
July 2018

Short-Term Hypoxia Dampens Inflammation in vivo via Enhanced Adenosine Release and Adenosine 2B Receptor Stimulation.

EBioMedicine 2018 Jul 4;33:144-156. Epub 2018 Jul 4.

Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, the Netherlands; Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085583PMC
July 2018

Host Genetic Signatures of Susceptibility to Fungal Disease.

Curr Top Microbiol Immunol 2018 Jul 25. Epub 2018 Jul 25.

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus de Gualtar, 4710-057, Braga, Portugal.

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http://dx.doi.org/10.1007/82_2018_113DOI Listing
July 2018

The mineralocorticoid receptor as a modulator of innate immunity and atherosclerosis.

Cardiovasc Res 2018 Jun;114(7):944-953

Department of Internal Medicine, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvy092DOI Listing
June 2018

Remembering Pathogen Dose: Long-Term Adaptation in Innate Immunity.

Trends Immunol 2018 06 30;39(6):438-445. Epub 2018 Apr 30.

Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.it.2018.04.001DOI Listing
June 2018

DNA methylation in childhood asthma: an epigenome-wide meta-analysis.

Lancet Respir Med 2018 05 26;6(5):379-388. Epub 2018 Feb 26.

GRIAC research institute Groningen, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands; Department of Pediatric Pulmonology and Pediatric Allergy, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(18)30052-3DOI Listing
May 2018

Innate immune memory: An evolutionary perspective.

Immunol Rev 2018 05;283(1):21-40

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/imr.12647DOI Listing
May 2018

Antifungal immune responses: emerging host-pathogen interactions and translational implications.

Genome Med 2018 05 25;10(1):39. Epub 2018 May 25.

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, 6525 GA, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s13073-018-0553-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968547PMC
May 2018

Differential Cytokine Induction by the Species of Cryptococcus gattii Complex.

Infect Immun 2018 04 22;86(4). Epub 2018 Mar 22.

Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia, Brazil

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http://dx.doi.org/10.1128/IAI.00958-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865019PMC
April 2018

Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses.

Diabetologia 2018 04 14;61(4):942-953. Epub 2018 Jan 14.

Nutrition, Metabolism and Genomics Group, Division of Human Nutrition, Wageningen University, Wageningen, the Netherlands.

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http://link.springer.com/10.1007/s00125-017-4526-6
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http://dx.doi.org/10.1007/s00125-017-4526-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448980PMC
April 2018

Is non-response to fluconazole maintenance therapy for recurrent Candida vaginitis related to sensitization to atopic reactions?

Am J Reprod Immunol 2018 04 22;79(4):e12811. Epub 2018 Feb 22.

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/aji.12811DOI Listing
April 2018

Physiological and Genetic Adaptations to Diving in Sea Nomads.

Cell 2018 04;173(3):569-580.e15

Centre for GeoGenetics, University of Copenhagen, Copenhagen 1350, Denmark; Department of Zoology, University of Cambridge, Cambridge, CB2 3EJ, UK; Wellcome Trust, Sanger Institute, Hinxton CB10 1SA, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.03.054DOI Listing
April 2018

Trained Innate Immunity as a Novel Mechanism Linking Infection and the Development of Atherosclerosis.

Circ Res 2018 Mar 24;122(5):664-669. Epub 2018 Jan 24.

From the Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands (J.L., S.B., L.A.B.J., M.G.N., N.P.R.); Department of Medical Genetics, University of Medicine and Pharmacy, Iuliu Haţieganu, Cluj-Napoca, Romania (L.A.B.J.); Department for Genomics & Immunoregulation, Life and Medical Sciences Institute, University of Bonn, Germany (M.G.N.); Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia (D.P.B.); and Department of Pediatrics, University of Melbourne, Parkville, Victoria, Australia (D.P.B.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.312465DOI Listing
March 2018

Role of glutathione metabolism in host defense against infection.

Proc Natl Acad Sci U S A 2018 03 14;115(10):E2320-E2328. Epub 2018 Feb 14.

Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1720833115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877983PMC
March 2018

Are histones real pathogenic agents in sepsis?

Nat Rev Immunol 2018 Feb 27;18(2):148. Epub 2017 Dec 27.

Department of Internal Medicine, and the Center for Infectious Diseases, Radboud University Medical Center, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, Netherlands.

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http://dx.doi.org/10.1038/nri.2017.157DOI Listing
February 2018

Cutting Edge: Induces Trained Innate Immunity.

J Immunol 2018 02 12;200(4):1243-1248. Epub 2018 Jan 12.

Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605;

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http://dx.doi.org/10.4049/jimmunol.1701010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927587PMC
February 2018

Identification of Discriminating Metabolic Pathways and Metabolites in Human PBMCs Stimulated by Various Pathogenic Agents.

Front Physiol 2018 27;9:139. Epub 2018 Feb 27.

Department of Experimental Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fphys.2018.00139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835230PMC
February 2018

The role of the interleukin-1 family in trained immunity.

Immunol Rev 2018 01;281(1):28-39

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/imr.12617DOI Listing
January 2018

BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity.

Cell Host Microbe 2018 Jan;23(1):89-100.e5

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2017.12.010DOI Listing
January 2018

Metabolic Induction of Trained Immunity through the Mevalonate Pathway.

Cell 2018 01;172(1-2):135-146.e9

Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.11.025DOI Listing
January 2018

Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.

Cell 2018 01;172(1-2):162-175.e14

Institute of Innate Immunity, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany; Department of Infectious Diseases & Immunology, UMass Medical School, Worcester, MA 01605, USA; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, 7491 Trondheim, Norway; German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324559PMC
January 2018

Patient Susceptibility to Candidiasis-A Potential for Adjunctive Immunotherapy.

J Fungi (Basel) 2018 Jan 9;4(1). Epub 2018 Jan 9.

Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.3390/jof4010009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872312PMC
January 2018