Mihaela M Mocanu

Mihaela M Mocanu

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Mihaela M Mocanu

Mihaela M Mocanu

Publications by authors named "Mihaela M Mocanu"

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Dipeptidyl peptidase-4 inhibitors and GLP-1 reduce myocardial infarct size in a glucose-dependent manner.

Cardiovasc Diabetol 2013 Oct 22;12:154. Epub 2013 Oct 22.

The Hatter Cardiovascular Institute, UCL Institute of Cardiovascular Science and NIHR University College London Hospitals Biomedical Research Centre, 67 Chenies Mews, London WC1E 6HX, UK.

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http://dx.doi.org/10.1186/1475-2840-12-154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815626PMC
October 2013

Cardioprotection in the aging, diabetic heart: the loss of protective Akt signalling.

Cardiovasc Res 2013 Sep 30;99(4):694-704. Epub 2013 May 30.

The Hatter Cardiovascular Institute, University College London, UK.

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http://dx.doi.org/10.1093/cvr/cvt140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746954PMC
September 2013

Glimepiride treatment facilitates ischemic preconditioning in the diabetic heart.

J Cardiovasc Pharmacol Ther 2013 May 21;18(3):263-9. Epub 2012 Dec 21.

The Hatter Cardiovascular Institute, University College London Hospital and Medical School, London, UK.

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http://dx.doi.org/10.1177/1074248412468945DOI Listing
May 2013

Chronic metformin associated cardioprotection against infarction: not just a glucose lowering phenomenon.

Cardiovasc Drugs Ther 2013 Feb;27(1):5-16

The Hatter Cardiovascular Institute, Institute of Cardiovascular Science, UCL, London, UK.

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http://dx.doi.org/10.1007/s10557-012-6425-xDOI Listing
February 2013

The Akt1 isoform is an essential mediator of ischaemic preconditioning.

J Cell Mol Med 2012 Aug;16(8):1739-49

The Hatter Cardiovascular Institute, The Institute of Cardiovascular Science, University College London, London, UK.

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http://dx.doi.org/10.1111/j.1582-4934.2011.01491.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822687PMC
August 2012

The diabetic heart: too sweet for its own good?

Cardiol Res Pract 2012 22;2012:845698. Epub 2012 Feb 22.

The Hatter Cardiovascular Institute, University College London, 67 Chenies Mews, London, WC1E 6HX, UK.

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http://dx.doi.org/10.1155/2012/845698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3296224PMC
August 2012

Retrograde heart perfusion: the Langendorff technique of isolated heart perfusion.

J Mol Cell Cardiol 2011 Jun 6;50(6):940-50. Epub 2011 Mar 6.

The Hatter Cardiovascular Institute, University College London Hospital and Medical School, 67 Chenies Mews, London WC1E 6HX, UK.

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http://dx.doi.org/10.1016/j.yjmcc.2011.02.018DOI Listing
June 2011

Enhancing AMPK activation during ischemia protects the diabetic heart against reperfusion injury.

Am J Physiol Heart Circ Physiol 2011 Jun 18;300(6):H2123-34. Epub 2011 Mar 18.

Hatter Cardiovascular Institute, Univ. College London Hospitals, 67 Chenies Mews, London, WC1E 6HX, UK.

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http://dx.doi.org/10.1152/ajpheart.00707.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119096PMC
June 2011

Failure of the adipocytokine, resistin, to protect the heart from ischemia-reperfusion injury.

J Cardiovasc Pharmacol Ther 2011 Mar 23;16(1):63-71. Epub 2010 Dec 23.

The Hatter Cardiovascular Institute, University College London Hospital and Medical School, London, UK.

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http://journals.sagepub.com/doi/10.1177/1074248410382232
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http://dx.doi.org/10.1177/1074248410382232DOI Listing
March 2011

Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction.

Cardiovasc Drugs Ther 2010 Feb;24(1):25-32

The Hatter Cardiovascular Institute, University College London Hospitals and Medical School, UK.

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http://dx.doi.org/10.1007/s10557-010-6222-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874156PMC
February 2010

Metformin prevents myocardial reperfusion injury by activating the adenosine receptor.

J Cardiovasc Pharmacol 2009 May;53(5):373-8

The Hatter Cardiovascular Institute, University College London Medical School, London, United Kingdom.

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http://dx.doi.org/10.1097/FJC.0b013e31819fd4e7DOI Listing
May 2009

Letter to the editor: "Zinc and cardioprotection: the missing link".

Am J Physiol Heart Circ Physiol 2009 Jan;296(1):H233-4; author reply H235

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http://dx.doi.org/10.1152/ajpheart.00985.2008DOI Listing
January 2009

Mitochondrial PINK1--a novel cardioprotective kinase?

Cardiovasc Drugs Ther 2008 Dec 30;22(6):507-8. Epub 2008 Sep 30.

The Hatter Cardiovascular Institute, University College London Hospital and Medical School, 67 Chenies Mews, London WC1E 6HX, UK.

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http://dx.doi.org/10.1007/s10557-008-6136-5DOI Listing
December 2008

Ischemia-reperfusion injury and cardioprotection: investigating PTEN, the phosphatase that negatively regulates PI3K, using a congenital model of PTEN haploinsufficiency.

Basic Res Cardiol 2008 Nov 5;103(6):560-8. Epub 2008 Jul 5.

The Hatter Cardiovascular Institute, University College London Hospital and Medical School, 67 Chenies Mews, London, WC1E 6HX, UK.

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http://dx.doi.org/10.1007/s00395-008-0735-yDOI Listing
November 2008

Metformin protects the ischemic heart by the Akt-mediated inhibition of mitochondrial permeability transition pore opening.

Basic Res Cardiol 2008 May 13;103(3):274-84. Epub 2007 Dec 13.

The Hatter Cardiovascular Institute, University College London Hospitals, London, WC1E 6HX, UK.

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http://dx.doi.org/10.1007/s00395-007-0691-yDOI Listing
May 2008

Myocardial ischaemia-reperfusion injury is attenuated by intact glucagon like peptide-1 (GLP-1) in the in vitro rat heart and may involve the p70s6K pathway.

Cardiovasc Drugs Ther 2007 Aug;21(4):253-6

The Hatter Institute and Centre for Cardiology, University College London Hospital & Medical School, Grafton Way, London, WC1E, UK.

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http://dx.doi.org/10.1007/s10557-007-6030-6DOI Listing
August 2007

A potential role for PTEN in the diabetic heart.

Cardiovasc Drugs Ther 2006 Aug;20(4):319-21

The Hatter Cardiovascular Institute, University College London Hospital and Medical School, Chenies Mew, London, WC1E 6HX, UK.

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http://dx.doi.org/10.1007/s10557-006-8876-4DOI Listing
August 2006

Pioglitazone mimics preconditioning in the isolated perfused rat heart: a role for the prosurvival kinases PI3K and P42/44MAPK.

J Cardiovasc Pharmacol 2005 Dec;46(6):817-22

The Hatter Institute and Centre for Cardiology, University College London Hospitals and Medical School, London, United Kingdom.

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http://dx.doi.org/10.1097/01.fjc.0000188365.07635.57DOI Listing
December 2005

Preconditioning the diabetic heart: the importance of Akt phosphorylation.

Diabetes 2005 Aug;54(8):2360-4

The Hatter Institute and Centre for Cardiology, University College London Hospitals, Grafton Way, London, WC1E 6DB, UK.

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http://dx.doi.org/10.2337/diabetes.54.8.2360DOI Listing
August 2005

Failure to protect the myocardium against ischemia/reperfusion injury after chronic atorvastatin treatment is recaptured by acute atorvastatin treatment: a potential role for phosphatase and tensin homolog deleted on chromosome ten?

J Am Coll Cardiol 2005 Apr;45(8):1287-91

Hatter Institute and Centre for Cardiology, University College London Hospital and Medical School, London, United Kingdom.

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http://dx.doi.org/10.1016/j.jacc.2005.01.021DOI Listing
April 2005

Atorvastatin and myocardial reperfusion injury: new pleiotropic effect implicating multiple prosurvival signaling.

J Cardiovasc Pharmacol 2005 Mar;45(3):247-52

Hatter Institute and Centre for Cardiology, University College London Hospitals and Medical School, London, United Kingdom.

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http://dx.doi.org/10.1097/01.fjc.0000154376.82445.06DOI Listing
March 2005

Ischemic preconditioning protects by activating prosurvival kinases at reperfusion.

Am J Physiol Heart Circ Physiol 2005 Feb 9;288(2):H971-6. Epub 2004 Sep 9.

The Hatter Institute, University College London Hospital, London, United Kingdom.

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http://www.physiology.org/doi/10.1152/ajpheart.00374.2004
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http://dx.doi.org/10.1152/ajpheart.00374.2004DOI Listing
February 2005

Glucagon-like peptide 1 can directly protect the heart against ischemia/reperfusion injury.

Diabetes 2005 Jan;54(1):146-51

The Hatter Institute for Cardiovascular Studies, University College London Hospital and Medical School, Grafton Way, London WC1E, UK.

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http://dx.doi.org/10.2337/diabetes.54.1.146DOI Listing
January 2005

Glucagon like peptide-1 is protective against myocardial ischemia/reperfusion injury when given either as a preconditioning mimetic or at reperfusion in an isolated rat heart model.

Cardiovasc Drugs Ther 2005 Jan;19(1):9-11

The Hatter Institute and Centre for Cardiology, University College London Hospital & Medical School, London, UK.

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http://dx.doi.org/10.1007/s10557-005-6892-4DOI Listing
January 2005

Heat shock protein 27 protects the heart against myocardial infarction.

Basic Res Cardiol 2004 Nov 13;99(6):392-4. Epub 2004 Jul 13.

The Hatter Institute and Centre for Cardiology, Universitiy College London Hospitals and Medical School London, Grafton Way, London WC1E 6DB, UK.

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http://dx.doi.org/10.1007/s00395-004-0483-6DOI Listing
November 2004

Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway.

Circ Res 2004 Aug 8;95(3):230-2. Epub 2004 Jul 8.

The Hatter Institute and Centre for Cardiology, University College London Hospital, London, UK.

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http://dx.doi.org/10.1161/01.RES.0000138303.76488.feDOI Listing
August 2004

Cross-talk between the survival kinases during early reperfusion: its contribution to ischemic preconditioning.

Cardiovasc Res 2004 Aug;63(2):305-12

The Hatter Institute and Centre for Cardiology, University College London Hospital, and Medical School, Grafton Way, London WC1E 6DB, UK.

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https://academic.oup.com/cardiovascres/article-lookup/doi/10
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http://dx.doi.org/10.1016/j.cardiores.2004.04.011DOI Listing
August 2004

p53 down-regulation: a new molecular mechanism involved in ischaemic preconditioning.

FEBS Lett 2003 Dec;555(2):302-6

The Hatter Institute and Centre for Cardiology, University College London Medical School, London WC1E 6DB, UK.

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http://dx.doi.org/10.1016/s0014-5793(03)01260-2DOI Listing
December 2003

Adenosine A(3) receptor activation protects the myocardium from reperfusion/reoxygenation injury.

Am J Physiol Heart Circ Physiol 2002 Oct;283(4):H1307-13

The Hatter Institute for Cardiovascular Studies, Division of Cardiology, University College London Hospitals and Medical School, United Kingdom.

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http://www.physiology.org/doi/10.1152/ajpheart.00851.2001
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http://dx.doi.org/10.1152/ajpheart.00851.2001DOI Listing
October 2002

PI3 kinase and not p42/p44 appears to be implicated in the protection conferred by ischemic preconditioning.

J Mol Cell Cardiol 2002 Jun;34(6):661-8

The Hatter Institute for Cardiovascular Studies, University College London Hospital and Medical School, London, UK.

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http://dx.doi.org/10.1006/jmcc.2002.2006DOI Listing
June 2002