Miguel Pignatelli

Miguel Pignatelli

UNVERIFIED PROFILE

Are you Miguel Pignatelli?   Register this Author

Register author
Miguel Pignatelli

Miguel Pignatelli

Publications by authors named "Miguel Pignatelli"

Are you Miguel Pignatelli?   Register this Author

40Publications

894Reads

19Profile Views

Designing an intuitive web application for drug discovery scientists.

Drug Discov Today 2018 06 11;23(6):1169-1174. Epub 2018 Jan 11.

Open Targets, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK; European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.drudis.2018.01.032DOI Listing
June 2018

Transcription Factor Activities Enhance Markers of Drug Sensitivity in Cancer.

Cancer Res 2018 02 11;78(3):769-780. Epub 2017 Dec 11.

European Molecular Biology Laboratory - European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-17-1679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522379PMC
February 2018

Ensembl comparative genomics resources.

Database (Oxford) 2016 20;2016. Epub 2016 Feb 20.

European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SD, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/database/bav096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761110PMC
October 2016

ncRNA orthologies in the vertebrate lineage.

Database (Oxford) 2016 15;2016. Epub 2016 Mar 15.

European Molecular Biology Laboratory, European Bioinformatics Institute UCL Cancer Institute, University College London, London WC1E 6BT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/database/bav127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792531PMC
October 2016

TnT: a set of libraries for visualizing trees and track-based annotations for the web.

Bioinformatics 2016 08 22;32(16):2524-5. Epub 2016 Apr 22.

Centre for Therapeutic Target Validation and European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btw210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978938PMC
August 2016

The Ensembl REST API: Ensembl Data for Any Language.

Bioinformatics 2015 Jan 17;31(1):143-5. Epub 2014 Sep 17.

European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD and Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD and Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btu613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271150PMC
January 2015

Enhancer evolution across 20 mammalian species.

Cell 2015 Jan;160(3):554-66

University of Cambridge, Cancer Research UK Cambridge Institute, Robinson Way, Cambridge, CB2 0RE, UK; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2015.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313353PMC
January 2015

A comparative encyclopedia of DNA elements in the mouse genome.

Authors:
Feng Yue Yong Cheng Alessandra Breschi Jeff Vierstra Weisheng Wu Tyrone Ryba Richard Sandstrom Zhihai Ma Carrie Davis Benjamin D Pope Yin Shen Dmitri D Pervouchine Sarah Djebali Robert E Thurman Rajinder Kaul Eric Rynes Anthony Kirilusha Georgi K Marinov Brian A Williams Diane Trout Henry Amrhein Katherine Fisher-Aylor Igor Antoshechkin Gilberto DeSalvo Lei-Hoon See Meagan Fastuca Jorg Drenkow Chris Zaleski Alex Dobin Pablo Prieto Julien Lagarde Giovanni Bussotti Andrea Tanzer Olgert Denas Kanwei Li M A Bender Miaohua Zhang Rachel Byron Mark T Groudine David McCleary Long Pham Zhen Ye Samantha Kuan Lee Edsall Yi-Chieh Wu Matthew D Rasmussen Mukul S Bansal Manolis Kellis Cheryl A Keller Christapher S Morrissey Tejaswini Mishra Deepti Jain Nergiz Dogan Robert S Harris Philip Cayting Trupti Kawli Alan P Boyle Ghia Euskirchen Anshul Kundaje Shin Lin Yiing Lin Camden Jansen Venkat S Malladi Melissa S Cline Drew T Erickson Vanessa M Kirkup Katrina Learned Cricket A Sloan Kate R Rosenbloom Beatriz Lacerda de Sousa Kathryn Beal Miguel Pignatelli Paul Flicek Jin Lian Tamer Kahveci Dongwon Lee W James Kent Miguel Ramalho Santos Javier Herrero Cedric Notredame Audra Johnson Shinny Vong Kristen Lee Daniel Bates Fidencio Neri Morgan Diegel Theresa Canfield Peter J Sabo Matthew S Wilken Thomas A Reh Erika Giste Anthony Shafer Tanya Kutyavin Eric Haugen Douglas Dunn Alex P Reynolds Shane Neph Richard Humbert R Scott Hansen Marella De Bruijn Licia Selleri Alexander Rudensky Steven Josefowicz Robert Samstein Evan E Eichler Stuart H Orkin Dana Levasseur Thalia Papayannopoulou Kai-Hsin Chang Arthur Skoultchi Srikanta Gosh Christine Disteche Piper Treuting Yanli Wang Mitchell J Weiss Gerd A Blobel Xiaoyi Cao Sheng Zhong Ting Wang Peter J Good Rebecca F Lowdon Leslie B Adams Xiao-Qiao Zhou Michael J Pazin Elise A Feingold Barbara Wold James Taylor Ali Mortazavi Sherman M Weissman John A Stamatoyannopoulos Michael P Snyder Roderic Guigo Thomas R Gingeras David M Gilbert Ross C Hardison Michael A Beer Bing Ren

Nature 2014 Nov;515(7527):355-64

Ludwig Institute for Cancer Research and University of California, San Diego School of Medicine, 9500 Gilman Drive, La Jolla, California 92093, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature13992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266106PMC
November 2014

TreeFam v9: a new website, more species and orthology-on-the-fly.

Nucleic Acids Res 2014 Jan 4;42(Database issue):D922-5. Epub 2013 Nov 4.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK and European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkt1055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965059PMC
January 2014

Comparison of different assembly and annotation tools on analysis of simulated viral metagenomic communities in the gut.

BMC Genomics 2014 Jan 18;15:37. Epub 2014 Jan 18.

Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunidad Valencia (FISABIO)-Salud Pública, Avenida de Cataluña 21, 46020 Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-15-37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901335PMC
January 2014

The oral metagenome in health and disease.

ISME J 2012 Jan 30;6(1):46-56. Epub 2011 Jun 30.

Department of Genomics and Health, Center for Advanced Research in Public Health, Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ismej.2011.85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246241PMC
January 2012

Evaluating the fidelity of de novo short read metagenomic assembly using simulated data.

PLoS One 2011 23;6(5):e19984. Epub 2011 May 23.

Unitat Mixta d'Investigació en Genòmica i Salut, Centre Superior d'Investigació en Salut Pública/UVEG-Institut Cavanilles, Valencia, Spain.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019984PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100316PMC
October 2011

Genome sequence of Lactococcus garvieae UNIUD074, isolated in Italy from a lactococcosis outbreak.

J Bacteriol 2011 Jul 20;193(14):3684-5. Epub 2011 May 20.

Área de Microbiología, Departamento de Biología Funcional, Facultad de Medicina, IUBA, Universidad de Oviedo, 33006 Oviedo, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JB.05210-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133331PMC
July 2011

Metatranscriptomic approach to analyze the functional human gut microbiota.

PLoS One 2011 Mar 8;6(3):e17447. Epub 2011 Mar 8.

Unidad Mixta de Investigación en Genómica y Salud-Centro Superior Investigación en Salud Pública (Generalitat Valenciana)/Instituto Cavanilles de Biodiversidad y Biología Evolutiva (Universitat de València), València, Spain.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017447PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050895PMC
March 2011

Environmental distribution of prokaryotic taxa.

BMC Microbiol 2010 Mar 22;10:85. Epub 2010 Mar 22.

Unidad Mixta de Investigación en Genómica y Salud, Centro Superior de Investigación en Salud Pública (CSISP) y Universidad de Valencia (Instituto Cavanilles de Biodiversidad y Biología Evolutiva), 46020 Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2180-10-85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850351PMC
March 2010

The human CD6 gene is transcriptionally regulated by RUNX and Ets transcription factors in T cells.

Mol Immunol 2009 Jul 14;46(11-12):2226-35. Epub 2009 May 14.

Servei d'Immunologia, Hospital Clínic Universitari de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Facultat de Medicina, Universitat de Barcelona, Villarroel 170, 08036 Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molimm.2009.04.018DOI Listing
July 2009

CROC: finding chromosomal clusters in eukaryotic genomes.

Bioinformatics 2009 Jun 23;25(12):1552-3. Epub 2009 Apr 23.

Instituto Cavanilles of Biodiversity and Evolutionary Biology, University of Valencia, Apdo, Valencia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btp248DOI Listing
June 2009

EnvDB, a database for describing the environmental distribution of prokaryotic taxa.

Environ Microbiol Rep 2009 Jun 29;1(3):191-7. Epub 2009 Apr 29.

Instituto Cavanilles de Biodiversidad y Biología Evolutiva, Universidad de Valencia, Polígono La Coma s/n, 46980 Paterna (Valencia), Spain. Centro Superior de Investigación en Salud Pública (CSISP), Dirección General de Salud Pública, C/San Vicente 83, 46007 Valencia, Spain. CIBER en Epidemiología y Salud Pública (CIBER-ESP), Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1758-2229.2009.00030.xDOI Listing
June 2009

Conserved chromosomal clustering of genes governed by chromatin regulators in Drosophila.

Genome Biol 2008 10;9(9):R134. Epub 2008 Sep 10.

Departament de Genètica and Institut de Biomedicina de la Universitat de Barcelona, Universitat de Barcelona, Barcelona, Catalonia, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/gb-2008-9-9-r134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592712PMC
January 2009

15-deoxy-Delta-12,14-prostaglandin J2 induces programmed cell death of breast cancer cells by a pleiotropic mechanism.

Carcinogenesis 2005 Jan 14;26(1):81-92. Epub 2004 Oct 14.

Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Arturo Duperier, 4, 28029, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgh308DOI Listing
January 2005

The transcription factor early growth response factor-1 (EGR-1) promotes apoptosis of neuroblastoma cells.

Biochem J 2003 Aug;373(Pt 3):739-46

Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Científicas-Universidad Autónoma, 28029 Madrid, Spain.

View Article

Download full-text PDF

Source
http://biochemj.org/lookup/doi/10.1042/bj20021918
Publisher Site
http://dx.doi.org/10.1042/BJ20021918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1223559PMC
August 2003

Enhancement of BRCA1 gene expression by the peroxisome proliferator-activated receptor gamma in the MCF-7 breast cancer cell line.

Oncogene 2003 Aug;22(35):5446-50

Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.onc.1206824DOI Listing
August 2003

CCAAT/enhancer-binding protein beta plays a regulatory role in differentiation and apoptosis of neuroblastoma cells.

J Biol Chem 2002 Feb 3;277(7):5460-7. Epub 2001 Dec 3.

Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Cientificas-Universidad Autónoma de Madrid, 28029-Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M108761200DOI Listing
February 2002