Publications by authors named "Miguel Angel Molina-Vila"

37Publications

RNA-Based Assay for Next-Generation Sequencing of Clinically Relevant Gene Fusions in Non-Small Cell Lung Cancer.

Authors:
Caterina De Luca Francesco Pepe Antonino Iaccarino Pasquale Pisapia Luisella Righi Angela Listì Lorenza Greco Gianluca Gragnano Severo Campione Gianfranco De Dominicis Fabio Pagni Roberta Sgariglia Mariantonia Nacchio Rossella Tufano Floriana Conticelli Elena Vigliar Claudio Bellevicine Diego Luigi Cortinovis Silvia Novello Miguel Angel Molina-Vila Rafael Rosell Giancarlo Troncone Umberto Malapelle

Cancers (Basel) 2021 Jan 4;13(1). Epub 2021 Jan 4.

Department of Public Health, University of Naples Federico II, 80131 Naples, Italy.

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January 2021

SRC and PIM1 as potential co-targets to overcome resistance in MET deregulated non-small cell lung cancer.

Authors:
Ilaria Attili Laura Bonanno Niki Karachaliou Jillian Wilhelmina Paulina Bracht Jordi Berenguer Carles Codony-Servat Jordi Codony-Servat Erika Aldeguer Ana Gimenez-Capitan Alessandro Dal Maso Matteo Fassan Imane Chaib Miguel Angel Molina-Vila Antonio Passaro Filippo de Marinis Giulia Pasello Valentina Guarneri Pier Franco Conte Rafael Rosell

Transl Lung Cancer Res 2020 Oct;9(5):1810-1821

Pangaea Oncology, Laboratory of Molecular Biology, Coyote Research Group, Quirón-Dexeus University Institute, Barcelona, Spain.

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October 2020

Anti-epidermal growth factor vaccine antibodies increase the antitumor activity of kinase inhibitors in ALK and RET rearranged lung cancer cells.

Authors:
Jordi Codony-Servat Silvia García-Roman Miguel Ángel Molina-Vila Jordi Bertran-Alamillo Santiago Viteri Erik d'Hondt Rafael Rosell

Transl Oncol 2021 Jan 23;14(1):100887. Epub 2020 Oct 23.

Instituto Oncológico Dr. Rosell (IOR), Quirón-Dexeus University Institute, Barcelona, Spain; Catalan Institute of Oncology, Badalona, Spain; Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Badalona, Spain.

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January 2021

Comprehensive cross-platform comparison of methods for non-invasive EGFR mutation testing: results of the RING observational trial.

Authors:
Atocha Romero Eloisa Jantus-Lewintre Beatriz García-Peláez Ana Royuela Amelia Insa Patricia Cruz Ana Collazo Javier Pérez Altozano Oscar Juan Vidal Pilar Diz Manuel Cobo Berta Hernández Sergio Vázquez Estevez Gretel Benítez Maria Guirado Margarita Majem Reyes Bernabé Ana Laura Ortega Ana Blasco Joaquim Bosch-Barrera Jose M Jurado Jorge García González Santiago Viteri Carlos Garcia Giron Bartomeu Massutí Ana Lopez Martín Alejandro Rodriguez-Festa Silvia Calabuig-Fariñas Miguel Ángel Molina-Vila Mariano Provencio

Mol Oncol 2021 Jan 13;15(1):43-56. Epub 2020 Nov 13.

Liquid Biopsy Laboratory, Biomedical Sciences Research Institute Puerta de Hierro-Majadahonda, Madrid, Spain.

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January 2021

Combination of gefitinib and olaparib versus gefitinib alone in EGFR mutant non-small-cell lung cancer (NSCLC): A multicenter, randomized phase II study (GOAL).

Authors:
Rosario Garcia-Campelo Oscar Arrieta Bartomeu Massuti Delvys Rodriguez-Abreu Ana Laura Ortega Granados Margarita Majem David Vicente Pilar Lianes Joaquim Bosch-Barrera Amelia Insa Manuel Dómine Noemí Reguart María Guirado María Ángeles Sala Sergio Vázquez-Estevez Reyes Bernabé Caro Ana Drozdowskyj Ana Verdú Niki Karachaliou Miguel Angel Molina-Vila Rafael Rosell

Lung Cancer 2020 12 3;150:62-69. Epub 2020 Oct 3.

Germans Trias i Pujol Research Institute and Hospital (IGTP), Badalona, Spain. Electronic address:

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December 2020

Precision medicine and its implementation in patients with NTRK fusion genes: perspective from developing countries.

Authors:
Andrés F Cardona Oscar Arrieta Alejandro Ruiz-Patiño Carolina Sotelo Nataly Zamudio-Molano Zyanya Lucia Zatarain-Barrón Luisa Ricaurte Luis Raez Marco Polo Peralta Álvarez Feliciano Barrón Leonardo Rojas Christian Rolfo Niki Karachaliou Miguel Angel Molina-Vila Rafael Rosell

Ther Adv Respir Dis 2020 Jan-Dec;14:1753466620938553

Germans Trias i Pujol Research Institute and Hospital (IGTP), Badalona, Catalunya, Spain.

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July 2020

Non-Small-Cell Lung Cancer Signaling Pathways, Metabolism, and PD-1/PD-L1 Antibodies.

Authors:
Mariacarmela Santarpia Andrés Aguilar Imane Chaib Andrés Felipe Cardona Sara Fancelli Fernando Laguia Jillian Wilhelmina Paulina Bracht Peng Cao Miguel Angel Molina-Vila Niki Karachaliou Rafael Rosell

Cancers (Basel) 2020 Jun 5;12(6). Epub 2020 Jun 5.

Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), 08916 Badalona, Spain.

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June 2020

Usefulness of Two Independent DNA and RNA Tissue-Based Multiplex Assays for the Routine Care of Advanced NSCLC Patients.

Authors:
Elba Marin Cristina Teixido Elena Carmona-Rocha Roxana Reyes Ainara Arcocha Nuria Viñolas MªCarmen Rodríguez-Mues Carlos Cabrera Marcelo Sánchez Ivan Vollmer Sergi Castillo Silvia Muñoz Ivana G Sullivan Adela Rodriguez Mireia Garcia Silvia Alos Pedro Jares Antonio Martinez Aleix Prat Miguel Ángel Molina-Vila Noemi Reguart

Cancers (Basel) 2020 Apr 30;12(5). Epub 2020 Apr 30.

Division of Medical Oncology, Hospital Clínic, 08036 Barcelona, Spain.

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April 2020

Evolution and Clinical Impact of EGFR Mutations in Circulating Free DNA in the BELIEF Trial.

Authors:
Miguel-Angel Molina-Vila Rolf A Stahel Urania Dafni Núria Jordana-Ariza Ariadna Balada-Bel Mónica Garzón-Ibáñez Beatriz García-Peláez Clara Mayo-de-Las-Casas Enriqueta Felip Alessandra Curioni Fontecedro Oliver Gautschi Solange Peters Bartomeu Massutí Ramon Palmero Santiago Ponce Aix Enric Carcereny Martin Früh Miklos Pless Sanjay Popat Sinead Cuffe Paolo Bidoli Roswitha Kammler Heidi Roschitzki-Voser Zoi Tsourti Niki Karachaliou Rafael Rosell

J Thorac Oncol 2020 03 5;15(3):416-425. Epub 2019 Dec 5.

Germans Trias i Pujol Research Institute and Hospital (IGTP), Badalona, Barcelona, Spain.

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March 2020

Targeting PKCι-PAK1 signaling pathways in EGFR and KRAS mutant adenocarcinoma and lung squamous cell carcinoma.

Authors:
Masaoki Ito Carles Codony-Servat Jordi Codony-Servat David Lligé Imane Chaib Xiaoyan Sun Jing Miao Rongwei Sun Xueting Cai Alberto Verlicchi Morihito Okada Miguel Angel Molina-Vila Niki Karachaliou Peng Cao Rafael Rosell

Cell Commun Signal 2019 10 28;17(1):137. Epub 2019 Oct 28.

Laboratory of Cellular and Molecular Biology, Institute for Health Science Research Germans Trias i Pujol (IGTP), Badalona, Spain.

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October 2019

Hsp90 inhibitors enhance the antitumoral effect of osimertinib in parental and osimertinib-resistant non-small cell lung cancer cell lines.

Authors:
Jordi Codony-Servat Santiago Viteri Carles Codony-Servat Masaoki Ito Jillian Willhelmina Paulina Bracht Jordi Berenguer Imane Chaib Miguel Angel Molina-Vila Niki Karachaliou Rafael Rosell

Transl Lung Cancer Res 2019 Aug;8(4):340-351

Instituto Oncológico Dr. Rosell (IOR), Quirón-Dexeus University Institute, Barcelona, Spain.

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August 2019

Mutations Classes I, II, and III in NSCLC Patients Included in the SLLIP Trial: The Need for a New Pre-Clinical Treatment Rationale.

Authors:
Jillian Wilhelmina Paulina Bracht Niki Karachaliou Trever Bivona Richard B Lanman Iris Faull Rebecca J Nagy Ana Drozdowskyj Jordi Berenguer Manuel Fernandez-Bruno Miguel Angel Molina-Vila Rafael Rosell

Cancers (Basel) 2019 Sep 17;11(9). Epub 2019 Sep 17.

Pangaea Oncology, Laboratory of Molecular Biology, Quirón-Dexeus University Institute, 08028 Barcelona, Spain.

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September 2019

Consistency and reproducibility of next-generation sequencing in cytopathology: A second worldwide ring trial study on improved cytological molecular reference specimens.

Authors:
Pasquale Pisapia Umberto Malapelle Gianluca Roma Sonika Saddar Qi Zheng Francesco Pepe Dario Bruzzese Elena Vigliar Claudio Bellevicine Rajyalakshmi Luthra Yuri E Nikiforov Clara Mayo-de-Las-Casas Miguel Angel Molina-Vila Rafael Rosell Michel Bihl Spasenija Savic Lukas Bubendorf Dario de Biase Giovanni Tallini David H Hwang Lynette M Sholl Sara Vander Borght Birgit Weynand Daniel Stieber Philippe Vielh Alessandra Rappa Massimo Barberis Matteo Fassan Massimo Rugge Carlos E De Andrea Maria D Lozano Cristiana Lupi Gabriella Fontanini Fernando Schmitt Catherine I Dumur Bettina Bisig Massimo Bongiovanni Sabine Merkelbach-Bruse Reinhard Büttner Marina N Nikiforova Sinchita Roy-Chowdhuri Giancarlo Troncone

Cancer Cytopathol 2019 05 25;127(5):285-296. Epub 2019 Apr 25.

Department of Public Health, University of Naples Federico II, Naples, Italy.

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May 2019

AURKB as a target in non-small cell lung cancer with acquired resistance to anti-EGFR therapy.

Authors:
Jordi Bertran-Alamillo Valérie Cattan Marie Schoumacher Jordi Codony-Servat Ana Giménez-Capitán Frédérique Cantero Mike Burbridge Sonia Rodríguez Cristina Teixidó Ruth Roman Josep Castellví Silvia García-Román Carles Codony-Servat Santiago Viteri Andrés-Felipe Cardona Niki Karachaliou Rafael Rosell Miguel-Angel Molina-Vila

Nat Commun 2019 04 18;10(1):1812. Epub 2019 Apr 18.

Laboratory of Oncology, Pangaea Oncology, Quiron Dexeus University Hospital, 08028, Barcelona, Spain.

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April 2019

Clinical Benefit From BRAF/MEK Inhibition in a Double Non-V600E BRAF Mutant Lung Adenocarcinoma: A Case Report.

Authors:
Roxana Reyes Clara Mayo-de-Las-Casas Cristina Teixidó Carlos Cabrera Elba Marín Ivan Vollmer Pedro Jares Mónica Garzón Miguel Ángel Molina-Vila Noemí Reguart

Clin Lung Cancer 2019 05 4;20(3):e219-e223. Epub 2019 Mar 4.

Department of Medical Oncology, Hospital Clínic, Barcelona, Spain; Translational Genomics and Targeted Therapeutics in Solid Tumors, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Electronic address:

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May 2019

Ubiquinol-cytochrome C reductase core protein II promotes tumorigenesis by facilitating p53 degradation.

Authors:
Yingyan Han Peng Wu Zhi Wang Zeyu Zhang Shujuan Sun Jia Liu Song Gong Peipei Gao Tomoo Iwakuma Miguel Angel Molina-Vila Benjamin Ping-Chi Chen Yu Zhang Teng Ji Qingqing Mo Pingbo Chen Junbo Hu Shixuan Wang Jianfeng Zhou Hua Lu Qinglei Gao

EBioMedicine 2019 Feb 20;40:92-105. Epub 2019 Jan 20.

Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. Electronic address:

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February 2019

Comutation and exclusion analysis in human tumors: A tool for cancer biology studies and for rational selection of multitargeted therapeutic approaches.

Authors:
Soledad Ochoa Elizabeth Martínez-Pérez Diego Javier Zea Miguel Angel Molina-Vila Cristina Marino-Buslje

Hum Mutat 2019 04 25;40(4):413-425. Epub 2019 Jan 25.

Fundación Instituto Leloir, Avda. Patricias Argentinas 435, Buenos Aires, Argentina.

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April 2019

Anti-Epidermal Growth Factor Vaccine Antibodies Enhance the Efficacy of Tyrosine Kinase Inhibitors and Delay the Emergence of Resistance in EGFR Mutant Lung Cancer Cells.

Authors:
Jordi Codony-Servat Silvia García-Roman Miguel Ángel Molina-Vila Jordi Bertran-Alamillo Ana Giménez-Capitán Santiago Viteri Andrés F Cardona Erik D'Hondt Niki Karachaliou Rafael Rosell

J Thorac Oncol 2018 09 8;13(9):1324-1337. Epub 2018 May 8.

Instituto Oncológico Dr. Rosell (IOR), Quirón-Dexeus University Institute, Barcelona, Spain; Catalan Institute of Oncology and Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Badalona, Spain.

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September 2018

Quantification and localization of oncogenic receptor tyrosine kinase variant transcripts using molecular inversion probes.

Authors:
Corina N A M van den Heuvel Arvid I Das Tessa de Bitter Femke Simmer Thomas Wurdinger Miguel Angel Molina-Vila William P J Leenders

Sci Rep 2018 05 4;8(1):7072. Epub 2018 May 4.

Department of Biochemistry, Radboud Institute for Molecular Life Sciences, University Medical Centre, Nijmegen, 6525 GA, The Netherlands.

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May 2018

RNA Analysis as a Tool to Determine Clinically Relevant Gene Fusions and Splice Variants.

Authors:
Cristina Teixidó Ana Giménez-Capitán Miguel Ángel Molina-Vila Vicente Peg Niki Karachaliou Alejandra Rodríguez-Capote Josep Castellví Rafael Rosell

Arch Pathol Lab Med 2018 Apr;142(4):474-479

From the Department of Pathology, Hospital Clínic, Barcelona, Spain (Dr Teixidó); Translational Genomics and Targeted Therapeutics in Solid Tumors, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain (Dr Teixidó); Pangaea Oncology, Oncology Laboratory, Dexeus University Hospital - Quirónsalud Group, Barcelona, Spain (Ms Giménez-Capitán and Drs Molina-Vila, Peg, Karachaliou, Castellví, and Rosell); the Department of Pathology, Hospital Universitario Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain (Drs Peg and Castellví); Morphological Sciences Department, Universitat Autònoma de Barcelona, Barcelona, Spain (Drs Peg and Castellví); Institute of Oncology Rosell (IOR), University Hospital Sagrat Cor and Quirónsalud Group, Barcelona, Spain (Drs Karachaliou and Rosell); the Department of Medical Oncology, Canarias University Hospital, San Cristóbal de La Laguna, Tenerife, Spain (Dr Rodríguez-Capote); and Cancer Biology & Precision Medicine Program, Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Badalona, Spain (Dr Rosell).

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April 2018