Publications by authors named "Miguel A Molina-Vila"

23Publications

Multiplex Detection of Clinically Relevant Mutations in Liquid Biopsies of Cancer Patients Using a Hybridization-Based Platform.

Authors:
Ana Giménez-Capitán Jillian Bracht Juan José García Núria Jordana-Ariza Beatriz García Mónica Garzón Clara Mayo-de-Las-Casas Santiago Viteri-Ramirez Alejandro Martinez-Bueno Andrés Aguilar Ivana-Gabriela Sullivan Eric Johnson Chung-Ying Huang Jay L Gerlach Sarah Warren Joseph M Beechem Cristina Teixidó Rafael Rosell Noemí Reguart Miguel A Molina-Vila

Clin Chem 2021 Jan 13. Epub 2021 Jan 13.

Pangaea Oncology, Laboratory of Oncology, Quirón Dexeus University Hospital, Barcelona, Spain.

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January 2021

RNA-Based Multiplexing Assay for Routine Testing of Fusion and Splicing Variants in Cytological Samples of NSCLC Patients.

Authors:
Cristina Aguado Ana Giménez-Capitán Ruth Román Sonia Rodríguez Núria Jordana-Ariza Andrés Aguilar Carlos Cabrera-Gálvez Carlos Rivas-Corredor Pilar Lianes Santiago Viteri Irene Moya Miguel A Molina-Vila

Diagnostics (Basel) 2020 Dec 23;11(1). Epub 2020 Dec 23.

Laboratorio de Oncología, Pangaea Oncology, Hospital Quirón Dexeus, 08028 Barcelona, Spain.

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December 2020

Multiplex RNA-based detection of clinically relevant MET alterations in advanced non-small cell lung cancer.

Authors:
Cristina Aguado Cristina Teixido Ruth Román Roxana Reyes Ana Giménez-Capitán Elba Marin Carlos Cabrera Nuria Viñolas Sergi Castillo Silvia Muñoz Ainara Arcocha Laura López-Vilaró Ivana Sullivan Erika Aldeguer Sonia Rodríguez Irene Moya Santiago Viteri Andrés Felipe Cardona Ramon Palmero Cristina Sainz Miguel Mesa-Guzmán Maria D Lozano Andrés Aguilar-Hernández Alejandro Martínez-Bueno María González-Cao Elena Gonzalvo William P J Leenders Rafael Rosell Luis M Montuenga Aleix Prat Miguel A Molina-Vila Noemi Reguart

Mol Oncol 2020 Nov 25. Epub 2020 Nov 25.

Translational Genomics and Targeted Therapeutics in Solid Tumors, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS).

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November 2020

Predictive molecular pathology in the time of coronavirus disease (COVID-19) in Europe.

Authors:
Umberto Malapelle Pasquale Pisapia Antonino Iaccarino Massimo Barberis Claudio Bellevicine Hans Brunnström Dario de Biase Giovanna De Maglio Kajsa Ericson Lindquist Matteo Fassan Gabriella Fontanini Elisa Gruppioni Paul Hofman Sabine Merkelbach-Bruse Miguel A Molina Vila Anaïs Pujals Ida Rapa Luisella Righi Rafael Rosell Oliver Schildgen Verena Schildgen Fernando C Schmitt Giovanni Tallini Sara Vander Borght Elena Vigliar Marco Volante Svenja Wagener-Ryczek Birgit Weynand Giancarlo Troncone

J Clin Pathol 2020 Jul 31. Epub 2020 Jul 31.

Department of Public Health, University of Naples Federico II, Naples, Italy

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July 2020

Assessment of the Feasibility and Safety of Durvalumab for Treatment of Solid Tumors in Patients With HIV-1 Infection: The Phase 2 DURVAST Study.

Authors:
Maria Gonzalez-Cao Teresa Morán Judith Dalmau Javier Garcia-Corbacho Jillian W P Bracht Reyes Bernabe Oscar Juan Javier de Castro Remei Blanco Ana Drozdowskyj Jordi Argilaguet Andreas Meyerhans Julia Blanco Julia G Prado Jorge Carrillo Bonaventura Clotet Bartomeu Massuti Mariano Provencio Miguel A Molina-Vila Clara Mayo de Las Casa Monica Garzon Peng Cao Chung-Ying Huang Javier Martinez-Picado Rafael Rosell

JAMA Oncol 2020 07;6(7):1063-1067

Translational Cancer Research Unit, Instituto Oncológico Dr Rosell, Dexeus University Hospital, Barcelona, Spain.

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July 2020

Detection of somatic mutations in peritoneal lavages and plasma of endometrial cancer patients: A proof-of-concept study.

Authors:
Clara Mayo-de-Las-Casas Ana Velasco Douglas Sanchez Alejandro Martínez-Bueno Mónica Garzón-Ibáñez Sònia Gatius Maria Ruiz-Miró Xavier Gonzalez-Tallada Ivana Llordella Francesc Tresserra Sonia Rodríguez Erika Aldeguer Berta Roman-Canal Jordi Bertran-Alamillo Beatriz García-Peláez Rafael Rosell Miguel A Molina-Vila Xavier Matias-Guiu

Int J Cancer 2020 Jul 17;147(1):277-284. Epub 2020 Feb 17.

Department of Pathology, Hospital Universitari Arnau de Vilanova, IRBLLEIDA, Lleida, Spain.

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July 2020

Prospective detection of mutations in cerebrospinal fluid, pleural effusion, and ascites of advanced cancer patients to guide treatment decisions.

Authors:
Sergio Villatoro Clara Mayo-de-Las-Casas Núria Jordana-Ariza Santiago Viteri-Ramírez Mónica Garzón-Ibañez Irene Moya-Horno Beatriz García-Peláez María González-Cao Umberto Malapelle Ariadna Balada-Bel Alejandro Martínez-Bueno Raquel Campos Noemí Reguart Margarita Majem Remei Blanco Ana Blasco María J Catalán Xavier González Giancarlo Troncone Niki Karachaliou Rafael Rosell Miguel A Molina-Vila

Mol Oncol 2019 12 11;13(12):2633-2645. Epub 2019 Oct 11.

Laboratory of Oncology, Pangaea Oncology, Quirón Dexeus University Hospital, Barcelona, Spain.

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December 2019

Response to crizotinib in a non-small-cell lung cancer patient harboring an fusion with an atypical insertion.

Authors:
Cristina Aguado Maria-de-Los-Llanos Gil Zaira Yeste Ana Giménez-Capitán Cristina Teixidó Niki Karachaliou Santiago Viteri Rafael Rosell Miguel A Molina-Vila

Onco Targets Ther 2018 1;11:1117-1120. Epub 2018 Mar 1.

Laboratory of Oncology, Pangaea Oncology.

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March 2018

Early evolution of BRAFV600 status in the blood of melanoma patients correlates with clinical outcome and identifies patients refractory to therapy.

Authors:
Maria Gonzalez-Cao Clara Mayo de Las Casas Nuria Jordana Ariza Jose L Manzano Miguel Á Molina-Vila Virtudes Soriano Teresa Puertolas Ariadna Balada Ainara Soria Margarita Majem Clara Montagut Eva Muñoz Delvys Rodriguez-Abreu Elisabeth Perez Almudena Garcia Javier Cortes Ana Drozdowskyj Niki Karachaliou Rafael Rosell

Melanoma Res 2018 06;28(3):195-203

Laboratory of Oncology, Institute of Oncology Dr Rosell (IOR), University Hospital Quirón Dexeus.

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June 2018

Consistency and reproducibility of next-generation sequencing and other multigene mutational assays: A worldwide ring trial study on quantitative cytological molecular reference specimens.

Authors:
Umberto Malapelle Clara Mayo-de-Las-Casas Miguel A Molina-Vila Rafael Rosell Spasenija Savic Michel Bihl Lukas Bubendorf Manuel Salto-Tellez Dario de Biase Giovanni Tallini David H Hwang Lynette M Sholl Rajyalakshmi Luthra Birgit Weynand Sara Vander Borght Edoardo Missiaglia Massimo Bongiovanni Daniel Stieber Philippe Vielh Fernando Schmitt Alessandra Rappa Massimo Barberis Francesco Pepe Pasquale Pisapia Nicola Serra Elena Vigliar Claudio Bellevicine Matteo Fassan Massimo Rugge Carlos E de Andrea Maria D Lozano Fulvio Basolo Gabriella Fontanini Yuri E Nikiforov Suzanne Kamel-Reid Gilda da Cunha Santos Marina N Nikiforova Sinchita Roy-Chowdhuri Giancarlo Troncone

Cancer Cytopathol 2017 Aug 5;125(8):615-626. Epub 2017 May 5.

Department of Public Health, University of Naples Federico II, Naples, Italy.

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August 2017

Erlotinib and bevacizumab in patients with advanced non-small-cell lung cancer and activating EGFR mutations (BELIEF): an international, multicentre, single-arm, phase 2 trial.

Authors:
Rafael Rosell Urania Dafni Enriqueta Felip Alessandra Curioni-Fontecedro Oliver Gautschi Solange Peters Bartomeu Massutí Ramon Palmero Santiago Ponce Aix Enric Carcereny Martin Früh Miklos Pless Sanjay Popat Athanasios Kotsakis Sinead Cuffe Paolo Bidoli Adolfo Favaretto Patrizia Froesch Noemí Reguart Javier Puente Linda Coate Fabrice Barlesi Daniel Rauch Michael Thomas Carlos Camps Jose Gómez-Codina Margarita Majem Rut Porta Riyaz Shah Emer Hanrahan Roswitha Kammler Barbara Ruepp Manuela Rabaglio Marie Kassapian Niki Karachaliou Rachel Tam David S Shames Miguel A Molina-Vila Rolf A Stahel

Lancet Respir Med 2017 05 10;5(5):435-444. Epub 2017 Apr 10.

University Hospital Zurich, Clinic of Oncology, Zurich, Switzerland; Swiss Group of Clinical Cancer Research, Bern, Switzerland. Electronic address:

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May 2017

Identification of , , and Fusions by a Multiplexed mRNA-Based Assay in Formalin-Fixed, Paraffin-Embedded Samples from Advanced Non-Small-Cell Lung Cancer Patients.

Authors:
Noemí Reguart Cristina Teixidó Ana Giménez-Capitán Laia Paré Patricia Galván Santiago Viteri Sonia Rodríguez Vicente Peg Erika Aldeguer Nuria Viñolas Jordi Remon Niki Karachaliou Esther Conde Fernando Lopez-Rios Ernest Nadal Sabine Merkelbach-Bruse Reinhard Büttner Rafael Rosell Miguel A Molina-Vila Aleix Prat

Clin Chem 2017 03 10;63(3):751-760. Epub 2017 Jan 10.

Medical Oncology, Hospital Clínic, Barcelona, Spain.

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March 2017

Liquid Biopsy in Non-Small Cell Lung Cancer.

Authors:
Miguel A Molina-Vila Clara Mayo-de-Las-Casas Ana Giménez-Capitán Núria Jordana-Ariza Mónica Garzón Ariadna Balada Sergi Villatoro Cristina Teixidó Beatriz García-Peláez Cristina Aguado María José Catalán Raquel Campos Ana Pérez-Rosado Jordi Bertran-Alamillo Alejandro Martínez-Bueno María-de-Los-Llanos Gil María González-Cao Xavier González Daniela Morales-Espinosa Santiago Viteri Niki Karachaliou Rafael Rosell

Front Med (Lausanne) 2016 23;3:69. Epub 2016 Dec 23.

Instituto Oncológico Dr Rosell, Quirón Dexeus University Hospital, Barcelona, Spain; Cancer Biology and Precision Medicine Program, Catalan Institute of Oncology, Germans Trias i Pujol Health Sciences Institute and Hospital, Badalona, Spain.

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December 2016

Coexistence of EGFR T790M mutation and common activating mutations in pretreatment non-small cell lung cancer: A systematic review and meta-analysis.

Authors:
Li-Yang Chen Miguel A Molina-Vila Sheng-Yuan Ruan Kang-Yi Su Wei-Yu Liao Kai-Lun Yu Chao-Chi Ho Jin-Yuan Shih Chong-Jen Yu James Chih-Hsin Yang Rafael Rosell Pan-Chyr Yang

Lung Cancer 2016 Apr 30;94:46-53. Epub 2016 Jan 30.

National Taiwan University, 1 Roosevelt Road Sec. 4, Taipei 100, Taiwan.

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April 2016

cfDNA analysis from blood in melanoma.

Authors:
Miguel A Molina-Vila Clara Mayo de-Las-Casas Jordi Bertran-Alamillo Nuria Jordana-Ariza María González-Cao Rafael Rosell

Ann Transl Med 2015 Nov;3(20):309

1 Laboratory of Oncology/Pangaea Biotech S.L, Hospital Quiron Dexeus, Barcelona, Spain ; 2 Translational Cancer Research Unit, Instituto Oncológico Dr Rosell, Quirón Dexeus University Hospital, Barcelona, Spain ; 3 Catalan Institute of Oncology, Hospital Germans Trias i Pujol Badalona, Barcelona, Spain.

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November 2015

BRAF mutation analysis in circulating free tumor DNA of melanoma patients treated with BRAF inhibitors.

Authors:
Maria Gonzalez-Cao Clara Mayo-de-Las-Casas Miguel A Molina-Vila Leticia De Mattos-Arruda Eva Muñoz-Couselo Jose L Manzano Javier Cortes Jose P Berros Ana Drozdowskyj Miguel Sanmamed Alvaro Gonzalez Carlos Alvarez Santiago Viteri Niki Karachaliou Salvador Martin Algarra Jordi Bertran-Alamillo Nuria Jordana-Ariza Rafael Rosell

Melanoma Res 2015 Dec;25(6):486-95

aTranslational Cancer Research Unit, Instituto Oncológico Dr Rosell, Quirón Dexeus University Hospital bPangaea Biotech S.L cHospital Vall d'Hebron dCatalan Institute of Oncology, Hospital Germans Trias i Pujol Badalona eMORe Foundation, Barcelona fHospital Central Asturias, Oviedo gPivotal SL, Madrid hCUN, Pamplona, Spain.

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December 2015

Kin-Driver: a database of driver mutations in protein kinases.

Authors:
Franco L Simonetti Cristian Tornador Nuria Nabau-Moretó Miguel A Molina-Vila Cristina Marino-Buslje

Database (Oxford) 2014 19;2014:bau104. Epub 2014 Nov 19.

Fundación Instituto Leloir, Av. Patricias Argentinas 435. C1405BWE, Buenos Aires, Argentina, Pompeu Fabra University (UPF), Dept. de Tecnologies de la Informació i les Comunicacions. Tanger 122-140 08018, Barcelona, Spain, Computational Genomics Laboratory, Genetics Department, Institut de Biologia Universitat de Barcelona (IBUB), Facultat de Biologia, Av Diagonal 645 and Breakthrough Cancer Research Unit, Dexeus University Hospital, Sabino Arana 5-19, Barcelona, Spain.

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July 2015

Nondisruptive p53 mutations are associated with shorter survival in patients with advanced non-small cell lung cancer.

Authors:
Miguel A Molina-Vila Jordi Bertran-Alamillo Amaya Gascó Clara Mayo-de-las-Casas María Sánchez-Ronco Laia Pujantell-Pastor Laura Bonanno Adolfo G Favaretto Andrés F Cardona Alain Vergnenègre Margarita Majem Bartomeu Massuti Teresa Morán Enric Carcereny Santiago Viteri Rafael Rosell

Clin Cancer Res 2014 Sep 2;20(17):4647-59. Epub 2014 Apr 2.

Hospital Germans Trias i Pujol, Badalona; Molecular Oncology Research Foundation (MORe), Barcelona;

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September 2014

Activating mutations cluster in the "molecular brake" regions of protein kinases and do not associate with conserved or catalytic residues.

Authors:
Miguel A Molina-Vila Nuria Nabau-Moretó Cristian Tornador Amit J Sabnis Rafael Rosell Xavier Estivill Trever G Bivona Cristina Marino-Buslje

Hum Mutat 2014 Mar 8;35(3):318-28. Epub 2014 Jan 8.

Breakthrough Cancer Research Unit, Dexeus University Hospital, Barcelona, Spain.

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March 2014

Impact of the new EGF receptor and ALK testing guideline on personalized lung cancer medicine.

Authors:
Miguel A Molina-Vila Cristina Teixidó Carlota Costa

Per Med 2013 Jul;10(5):415-417

Breakthrough Cancer Research Unit, Pangaea Biotech, Quiron Dexeus University Hospital, Barcelona, Spain.

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July 2013