Publications by authors named "Miguel A Japón"

42Publications

p53 and FBXW7: Sometimes Two Guardians Are Worse than One.

Cancers (Basel) 2020 Apr 16;12(4). Epub 2020 Apr 16.

Departamento de Microbiología, Facultad de Biología, Universidad de Sevilla, E-41012 Sevilla, Spain.

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http://dx.doi.org/10.3390/cancers12040985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225930PMC
April 2020

E-cadherin expression is associated with somatostatin analogue response in acromegaly.

J Cell Mol Med 2019 05 6;23(5):3088-3096. Epub 2019 Mar 6.

Unidad de Gestión de Endocrinología y Nutrición, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain.

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http://dx.doi.org/10.1111/jcmm.13851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484433PMC
May 2019

Association between dopamine and somatostatin receptor expression and pharmacological response to somatostatin analogues in acromegaly.

J Cell Mol Med 2018 03 21;22(3):1640-1649. Epub 2017 Dec 21.

Unidad de Gestión de Endocrinología y Nutrición, Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Sevilla, Spain.

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http://dx.doi.org/10.1111/jcmm.13440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824369PMC
March 2018

Both p62/SQSTM1-HDAC6-dependent autophagy and the aggresome pathway mediate CDK1 degradation in human breast cancer.

Sci Rep 2017 08 30;7(1):10078. Epub 2017 Aug 30.

Departamento de Microbiología, Facultad de Biología, Universidad de Sevilla, Seville, E-41012, Spain.

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http://dx.doi.org/10.1038/s41598-017-10506-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577189PMC
August 2017

Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer.

Oncotarget 2016 Aug;7(33):52751-52765

Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.

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http://dx.doi.org/10.18632/oncotarget.10481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288146PMC
August 2016

Loss of PKCδ Induces Prostate Cancer Resistance to Paclitaxel through Activation of Wnt/β-Catenin Pathway and Mcl-1 Accumulation.

Mol Cancer Ther 2016 07 13;15(7):1713-25. Epub 2016 Apr 13.

Instituto de Biomedicina de Sevilla (IBIS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Spain. Department of Pathology, Hospital Universitario Virgen del Rocío, Seville, Spain.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0951DOI Listing
July 2016

In1-ghrelin splicing variant is overexpressed in pituitary adenomas and increases their aggressive features.

Sci Rep 2015 Mar 4;5:8714. Epub 2015 Mar 4.

Department of Cell Biology, Physiology and Immunology, University of Cordoba, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Hospital Universitario Reina Sofia; CIBER Fisiopatología de la Obesidad y Nutrición; and Campus de Excelencia Internacional Agroalimentario (ceiA3), 14014 Córdoba, Spain.

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http://dx.doi.org/10.1038/srep08714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649711PMC
March 2015

Somatotropinomas, but not nonfunctioning pituitary adenomas, maintain a functional apoptotic RET/Pit1/ARF/p53 pathway that is blocked by excess GDNF.

Endocrinology 2014 Nov 19;155(11):4329-40. Epub 2014 Aug 19.

Centre for Investigations in Medicine of the USC (E.D.-R., A.R.G.-G., M.G.-L., C.D., C.V.A.), University of Santiago de Compostela, Santiago de Compostela, Spain 15782; Department of Endocrinology (I.B.), University Hospital (University Hospital of Santiago de Compostela), Instituto de Investigación Sanitaria, Santiago de Compostela, Spain 15706; Departments of Cell Biology, Physiology, and Immunology (A.I.-C., E.G.-P., R.M.L., J.P.C.), and Morphological Sciences (L.J.-R.), University of Cordoba, and Reina Sofia University Hospital (P.B., M.A.G.), Maimonides Institute for Research in Biomedicine of Cordoba, Córdoba, Spain 14014; Departments of Endocrinology and Pathology (A.L., M.A.J., A.S., E.V.), Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla, University of Sevilla, Sevilla, Spain 41013; Department of Endocrinology (F.J.T.), Hospital Virgen de la Victoria, and Department of Endocrinology (J.A.G.-A.), Hospital Carlos Haya, Malaga, Spain 29010; and CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn) 15706, spain (A.I.-C., F.J.T., P.B., I.B., C.D., R.M.L., J.P.C., C.V.A.), Spain 15706.

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http://dx.doi.org/10.1210/en.2014-1034DOI Listing
November 2014

Prostate cancer cell response to paclitaxel is affected by abnormally expressed securin PTTG1.

Mol Cancer Ther 2014 Oct 13;13(10):2372-83. Epub 2014 Aug 13.

Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío, CSIC, Universidad de Sevilla, Seville, Spain. Department of Pathology, Hospital Universitario Virgen del Rocío, Seville, Spain.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0405DOI Listing
October 2014

SCF(FBXW7α) modulates the intra-S-phase DNA-damage checkpoint by regulating Polo like kinase-1 stability.

Oncotarget 2014 Jun;5(12):4370-83

Departamento de Microbiología, Facultad de Biología, Universidad de Sevilla. Apartado de correos 1095. 41080-Sevilla, Spain.

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http://www.oncotarget.com/fulltext/2021
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147330PMC
http://dx.doi.org/10.18632/oncotarget.2021DOI Listing
June 2014

Prognostic value of CtIP/RBBP8 expression in breast cancer.

Cancer Med 2013 Dec 3;2(6):774-83. Epub 2013 Oct 3.

Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Av. Americo Vespucio s/n, Sevilla, 41092, Spain.

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http://doi.wiley.com/10.1002/cam4.141
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http://dx.doi.org/10.1002/cam4.141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892382PMC
December 2013

A single mutation in Securin induces chromosomal instability and enhances cell invasion.

Eur J Cancer 2013 Jan 18;49(2):500-10. Epub 2012 Jul 18.

Departamento de Microbiología, Facultad de Biología, Universidad de Sevilla, Sevilla, Spain.

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http://dx.doi.org/10.1016/j.ejca.2012.06.024DOI Listing
January 2013

Downregulation of protein tyrosine phosphatase PTPL1 alters cell cycle and upregulates invasion-related genes in prostate cancer cells.

Clin Exp Metastasis 2012 Apr 25;29(4):349-58. Epub 2012 Jan 25.

Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Avenida Manuel Siurot s/n, 41013 Seville, Spain.

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http://link.springer.com/10.1007/s10585-012-9455-7
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http://dx.doi.org/10.1007/s10585-012-9455-7DOI Listing
April 2012

Paclitaxel sensitivity of breast cancer cells requires efficient mitotic arrest and disruption of Bcl-xL/Bak interaction.

Breast Cancer Res Treat 2012 Jun 11;133(3):917-28. Epub 2011 Nov 11.

Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Avenida Manuel Siurot s/n, Seville 41013, Spain.

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http://dx.doi.org/10.1007/s10549-011-1864-9DOI Listing
June 2012

Craniopharyngiomas express embryonic stem cell markers (SOX2, OCT4, KLF4, and SOX9) as pituitary stem cells but do not coexpress RET/GFRA3 receptors.

J Clin Endocrinol Metab 2012 Jan 26;97(1):E80-7. Epub 2011 Oct 26.

Instituto de Investigaciones Sanitarias & Centro de Investigaciones Médicas de la USC (IDIS-CIMUS), Department of Physiology, School of Medicine, University of Santiago de Compostela (USC), E-15782 Santiago de Compostela, Spain.

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http://dx.doi.org/10.1210/jc.2011-2187DOI Listing
January 2012

Differential expression of THOC1 and ALY mRNP biogenesis/export factors in human cancers.

BMC Cancer 2011 Feb 17;11:77. Epub 2011 Feb 17.

Centro Andaluz de Biología Molecular y Medicina Regenerativa CABIMER, Universidad de Sevilla-CSIC, Av, Américo Vespucio s/n, 41092 Sevilla, Spain.

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http://dx.doi.org/10.1186/1471-2407-11-77DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050854PMC
February 2011

Immunohistochemical expression of Hsp60 correlates with tumor progression and hormone resistance in prostate cancer.

Urology 2010 Oct 12;76(4):1017.e1-6. Epub 2010 Aug 12.

Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.

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http://dx.doi.org/10.1016/j.urology.2010.05.045DOI Listing
October 2010

Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation.

Mol Biol Cell 2009 Jul 28;20(14):3353-62. Epub 2009 May 28.

Centro Andaluz de Biología Molecular y Medicina Regenerativa, CABIMER-CSIC, 41092 Sevilla, Spain.

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http://dx.doi.org/10.1091/mbc.e08-09-0965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2710844PMC
July 2009

Methylation alterations are not a major cause of PTTG1 misregulation.

BMC Cancer 2008 Apr 21;8:110. Epub 2008 Apr 21.

Service of General Surgery-B, Hospital Universitario 12 de Octubre, Madrid, 28041, Spain.

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http://dx.doi.org/10.1186/1471-2407-8-110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2377271PMC
April 2008

Clinicopathological correlations of Bcl-xL and Bax expression in differentiated thyroid carcinoma.

Clin Endocrinol (Oxf) 2008 Feb 4;68(2):190-7. Epub 2007 Sep 4.

Endocrinology Unit, Hospital Universitario Virgen del Rocio, Seville, Spain.

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http://dx.doi.org/10.1111/j.1365-2265.2007.03018.xDOI Listing
February 2008

Bcl-xL is overexpressed in hormone-resistant prostate cancer and promotes survival of LNCaP cells via interaction with proapoptotic Bak.

Endocrinology 2006 Oct 22;147(10):4960-7. Epub 2006 Jun 22.

Department of Pathology, Hospitales Universitarios Virgen del Rocío, Avenida Manuel Siurot s/n, Seville 41013, Spain.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2006-0502DOI Listing
October 2006

Prognostic significance of human pituitary tumor-transforming gene immunohistochemical expression in differentiated thyroid cancer.

J Clin Endocrinol Metab 2006 Apr 17;91(4):1404-9. Epub 2006 Jan 17.

Department of Pathology, Hospital Universitario Virgen del Rocío, Avenida Manuel Siurot s/n, Seville 41013, Spain.

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http://dx.doi.org/10.1210/jc.2005-2532DOI Listing
April 2006

Securin is a target of the UV response pathway in mammalian cells.

Mol Cell Biol 2004 Apr;24(7):2720-33

Departamento de Microbiología, Facultad de Biología, Universidad de Sevilla, 41013 Seville Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC371137PMC
http://dx.doi.org/10.1128/mcb.24.7.2720-2733.2004DOI Listing
April 2004

Bone involvement and abcess formation by neutrophil-rich CD30+ anaplastic large-cell lymphoma mimicking skeletal infection in an AIDS patient.

J Infect 2003 Jul;47(1):73-6

Servicio de Medicina Interna, Hospital Universitario de Valme, Carretera de Cádiz s/n, Sevilla, Spain.

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http://dx.doi.org/10.1016/s0163-4453(03)00005-7DOI Listing
July 2003

Evaluation of germline sequence variants of GFRA1, GFRA2, and GFRA3 genes in a cohort of Spanish patients with sporadic medullary thyroid cancer.

Thyroid 2002 Nov;12(11):1017-22

Unidad de Genética Médica y Diagnóstico Prenatal, Hospitales Universitarios Virgen del Rocío, Sevilla, Spain.

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http://dx.doi.org/10.1089/105072502320908367DOI Listing
November 2002

Expression of hpttg proto-oncogene in lymphoid neoplasias.

Oncogene 2002 Nov;21(53):8173-7

Department of Pathology, Hospital Universitario Virgen del Rocío, Seville, 41013 Spain.

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http://dx.doi.org/10.1038/sj.onc.1205954DOI Listing
November 2002

Primary lymphoma of the central nervous system and HTLV-I infection.

Haematologia (Budap) 2002 ;31(4):365-7

Department of Internal Medicine, Virgen del Rocío University Hospital, Seville, Spain.

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http://dx.doi.org/10.1163/15685590160141404DOI Listing
November 2002

Glial-derived neurotropic factor and RET gene expression in normal human anterior pituitary cell types and in pituitary tumors.

J Clin Endocrinol Metab 2002 Apr;87(4):1879-84

Department of Pathology, Hospital Universitario Virgen del Rocío, 41013 Sevilla, Spain.

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http://dx.doi.org/10.1210/jcem.87.4.8383DOI Listing
April 2002