Miguel A Sosa

Miguel A Gama Sosa

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Miguel A Sosa

Miguel A Gama Sosa

Publications by authors named "Miguel A Gama Sosa"

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1PubMed Central Citations

Blast-induced "PTSD": Evidence from an animal model.

Neuropharmacology 2019 02 15;145(Pt B):220-229. Epub 2018 Sep 15.

Department of Neurology, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY 10029, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY 10029, USA; Mount Sinai Alzheimer's Disease Research Center and the Ronald M. Loeb Center for Alzheimer's Disease, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Neurology Service, James J. Peters Department of Veterans Affairs Medical Center, 130 West Kingsbridge Road, Bronx, NY 10468, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2018.09.023DOI Listing
February 2019

Chronic post-traumatic stress disorder-related traits in a rat model of low-level blast exposure.

Behav Brain Res 2018 03 28;340:117-125. Epub 2016 Sep 28.

Department of Neurology, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY 10029, USA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY 10029, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY 10029, USA; Neurology Service, James J. Peters Department of Veterans Affairs Medical Center, 130 West Kingsbridge Road, Bronx, NY 10468, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2016.09.061DOI Listing
March 2018

Exposure to a Predator Scent Induces Chronic Behavioral Changes in Rats Previously Exposed to Low-level Blast: Implications for the Relationship of Blast-Related TBI to PTSD.

Front Neurol 2016 18;7:176. Epub 2016 Oct 18.

Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Neurology Service, James J. Peters Department of Veterans Affairs Medical Center, Bronx, NY, USA.

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http://dx.doi.org/10.3389/fneur.2016.00176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067529PMC
October 2016

Fibroblast growth factor rescues brain endothelial cells lacking presenilin 1 from apoptotic cell death following serum starvation.

Sci Rep 2016 07 22;6:30267. Epub 2016 Jul 22.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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http://dx.doi.org/10.1038/srep30267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957214PMC
July 2016

Presenilin 1 is necessary for neuronal, but not glial, EGFR expression and neuroprotection via γ-secretase-independent transcriptional mechanisms.

FASEB J 2015 Sep 18;29(9):3702-12. Epub 2015 May 18.

*Departments of Psychiatry and Neuroscience, Center for Molecular Biology and Genetics of Neurodegeneration, Icahn School of Medicine at Mount Sinai, New York, New York, USA; School of Medicine, University of Crete, Heraklion, Crete, Greece; and James J. Peters Department of Veterans Affairs Medical Center, General Medical Research Service, Bronx, New York, USA

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http://www.fasebj.org/content/29/9/3702.full.pdf
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http://www.fasebj.org/cgi/doi/10.1096/fj.15-270645
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http://dx.doi.org/10.1096/fj.15-270645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550373PMC
September 2015

Neuronal DNA Methylation Profiling of Blast-Related Traumatic Brain Injury.

J Neurotrauma 2015 Aug 7;32(16):1200-9. Epub 2015 May 7.

3 Friedman Brain Institute, Icahn School of Medicine at Mount Sinai , New York, New York.

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http://dx.doi.org/10.1089/neu.2014.3640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532898PMC
August 2015

Vascular and inflammatory factors in the pathophysiology of blast-induced brain injury.

Front Neurol 2015 16;6:48. Epub 2015 Mar 16.

Department of Neurotrauma, Operational and Undersea Medicine Directorate, Naval Medical Research Center , Silver Spring, MD , USA.

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http://dx.doi.org/10.3389/fneur.2015.00048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360816PMC
April 2015

Introduction of the human AVPR1A gene substantially alters brain receptor expression patterns and enhances aspects of social behavior in transgenic mice.

Dis Model Mech 2014 Aug 12;7(8):1013-22. Epub 2014 Jun 12.

Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA Friedman Brain Institute and Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA

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http://dmm.biologists.org/cgi/doi/10.1242/dmm.017053
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http://dx.doi.org/10.1242/dmm.017053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4107330PMC
August 2014

A critical role for human caspase-4 in endotoxin sensitivity.

J Immunol 2014 Jul 30;193(1):335-43. Epub 2014 May 30.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029; and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029

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http://dx.doi.org/10.4049/jimmunol.1303424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4066208PMC
July 2014

Presenilin-1 regulates the constitutive turnover of the fibronectin matrix in endothelial cells.

BMC Biochem 2012 Dec 21;13:28. Epub 2012 Dec 21.

Neurology Service, James J, Peters Department of Veterans Affairs Medical Center, Bronx, NY 10468, USA.

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http://dx.doi.org/10.1186/1471-2091-13-28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556133PMC
December 2012

Acute blast injury reduces brain abeta in two rodent species.

Front Neurol 2012 21;3:177. Epub 2012 Dec 21.

Research and Development Service, James J. Peters Department of Veterans Affairs Medical Center Bronx, NY, USA ; Department of Psychiatry, Mount Sinai School of Medicine New York, NY, USA ; Friedman Brain Institute, Mount Sinai School of Medicine New York, NY, USA.

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http://dx.doi.org/10.3389/fneur.2012.00177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527696PMC
December 2012

Blast exposure induces post-traumatic stress disorder-related traits in a rat model of mild traumatic brain injury.

J Neurotrauma 2012 Nov 27;29(16):2564-75. Epub 2012 Aug 27.

Neurology Service, James J. Peters Department of Veterans Affairs Medical Center, Bronx, New York 10468, USA.

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http://dx.doi.org/10.1089/neu.2012.2510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495123PMC
November 2012

Modeling human neurodegenerative diseases in transgenic systems.

Hum Genet 2012 Apr 14;131(4):535-63. Epub 2011 Dec 14.

Research and Development Service, James J. Peters Department of Veterans Affairs Medical Center, Bronx, NY 10468, USA.

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http://link.springer.com/10.1007/s00439-011-1119-1
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http://dx.doi.org/10.1007/s00439-011-1119-1DOI Listing
April 2012

PERIPHERAL MYELIN PROTEIN-22 IS EXPRESSED IN CNS MYELIN.

Transl Neurosci 2010 Dec;1(4):282-285

Research and Development, James J. Peters Department of Veterans Affairs Medical Center, Bronx, New York 10468, USA.

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http://dx.doi.org/10.2478/v10134-010-0038-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093192PMC
December 2010

Presenilin-1 regulates induction of hypoxia inducible factor-1α: altered activation by a mutation associated with familial Alzheimer's disease.

Mol Neurodegener 2010 Sep 23;5:38. Epub 2010 Sep 23.

Neurology Service, James J Peters Department of Veterans Affairs Medical Center, Bronx, NY 10468, USA.

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http://dx.doi.org/10.1186/1750-1326-5-38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955646PMC
September 2010

Transgenic mouse models of Alzheimer's disease.

Mt Sinai J Med 2010 Jan-Feb;77(1):69-81

Neurology Service, James J. Peters Department of Veterans Affairs Medical Center, Bronx, NY, USA.

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http://dx.doi.org/10.1002/msj.20159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925685PMC
April 2010

Presenilin transgenic mice as models of Alzheimer's disease.

Brain Struct Funct 2010 Mar 18;214(2-3):127-43. Epub 2009 Nov 18.

Neurology Service (3E16), James J. Peters Department of Veterans Affairs Medical Center, 130 West Kingsbridge Road, Bronx, NY, 10468, USA.

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http://dx.doi.org/10.1007/s00429-009-0227-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527905PMC
March 2010

Animal transgenesis: an overview.

Brain Struct Funct 2010 Mar 25;214(2-3):91-109. Epub 2009 Nov 25.

Department of Psychiatry, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY, 10029, USA.

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http://dx.doi.org/10.1007/s00429-009-0230-8DOI Listing
March 2010

Pepsin pretreatment allows collagen IV immunostaining of blood vessels in adult mouse brain.

J Neurosci Methods 2007 Jun 25;163(1):76-82. Epub 2007 Feb 25.

Department of Psychiatry, Box 1230, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.jneumeth.2007.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1931483PMC
June 2007

Research update: neurogenesis in adult brain and neuropsychiatric disorders.

Mt Sinai J Med 2006 Nov;73(7):931-40

Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA.

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November 2006

Altered ultrasonic vocalization in mice with a disruption in the Foxp2 gene.

Proc Natl Acad Sci U S A 2005 Jul 27;102(27):9643-8. Epub 2005 Jun 27.

Molecular Cardiology Research Center, Department of Medicine, University of Pennsylvania Medical Center, 956 Biomedical Research Building II/III, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1073/pnas.0503739102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160518PMC
July 2005

Neural progenitor cells do not differentiate prematurely in presenilin-1 null mutant mice.

Neurosci Lett 2004 Nov;371(2-3):249-54

Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/j.neulet.2004.09.038DOI Listing
November 2004

Human midsized neurofilament subunit induces motor neuron disease in transgenic mice.

Exp Neurol 2003 Nov;184(1):408-19

Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1016/s0014-4886(03)00206-1DOI Listing
November 2003