Michiel van der Flier

Michiel van der Flier

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Michiel van der Flier

Michiel van der Flier

Publications by authors named "Michiel van der Flier"

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41Publications

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Limited Innovations After More Than 65 Years of Immunoglobulin Replacement Therapy: Potential of IgA- and IgM-Enriched Formulations to Prevent Bacterial Respiratory Tract Infections.

Front Immunol 2018 23;9:1925. Epub 2018 Aug 23.

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Nijmegen, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2018.01925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115500PMC
September 2019

Biosynthetic homeostasis and resilience of the complement system in health and infectious disease.

EBioMedicine 2019 Jul 29;45:303-313. Epub 2019 Jun 29.

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands; Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.ebiom.2019.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642076PMC
July 2019

Common Genetic Variants in the Complement System and their Potential Link with Disease Susceptibility and Outcome of Invasive Bacterial Infection.

J Innate Immun 2020 3;12(2):131-141. Epub 2019 Jul 3.

Section Paediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Nijmegen, The Netherlands,

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http://dx.doi.org/10.1159/000500545DOI Listing
July 2019

Pharmacokinetics, Short-term Safety and Efficacy of the Approved Once-daily Darunavir/Ritonavir Dosing Regimen in HIV-infected Children.

Pediatr Infect Dis J 2018 10;37(10):1008-1010

Department of Pediatrics, Division of Infectious Diseases and Immunology, Erasmus MC University Medical Center-Sophia Children's Hospital, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1097/INF.0000000000001964DOI Listing
October 2018

Streptococcus pneumoniae PspC Subgroup Prevalence in Invasive Disease and Differences in Contribution to Complement Evasion.

Infect Immun 2018 04 22;86(4). Epub 2018 Mar 22.

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands

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http://dx.doi.org/10.1128/IAI.00010-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865030PMC
April 2018

Topical vancomycin reduces the cerebrospinal fluid shunt infection rate: A retrospective cohort study.

PLoS One 2018 9;13(1):e0190249. Epub 2018 Jan 9.

Department of Internal Medicine, and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190249PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760031PMC
February 2018

IgM Augments Complement Bactericidal Activity with Serum from a Patient with a Novel CD79a Mutation.

J Clin Immunol 2018 02 15;38(2):185-192. Epub 2018 Jan 15.

Section Pediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10875-017-0474-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840230PMC
February 2018

In vivo and in vitro palatability testing of a new paediatric formulation of valaciclovir.

Br J Clin Pharmacol 2017 12 20;83(12):2789-2797. Epub 2017 Sep 20.

Institute of Medical Sciences, Infection, Immunity and Inflammation Research Group; Aberdeen Fungal Group, University of Aberdeen, UK.

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http://dx.doi.org/10.1111/bcp.13396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698570PMC
December 2017

Ataxia-telangiectasia: recommendations for multidisciplinary treatment.

Dev Med Child Neurol 2017 07 20;59(7):680-689. Epub 2017 Mar 20.

Department of Neurology, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/dmcn.13424DOI Listing
July 2017

Ataxia-telangiectasia: Immunodeficiency and survival.

Clin Immunol 2017 05 24;178:45-55. Epub 2017 Jan 24.

Department of Neurology - Pediatric Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.clim.2017.01.009DOI Listing
May 2017

A versatile assay to determine bacterial and host factors contributing to opsonophagocytotic killing in hirudin-anticoagulated whole blood.

Sci Rep 2017 02 8;7:42137. Epub 2017 Feb 8.

Laboratory of Pediatric Infectious Diseases, Radboud Center for Infectious Diseases, Radboud university medical center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/srep42137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296863PMC
February 2017

Alternative pathway regulation by factor H modulates Streptococcus pneumoniae induced proinflammatory cytokine responses by decreasing C5a receptor crosstalk.

Cytokine 2016 12 6;88:281-286. Epub 2016 Oct 6.

Laboratory of Pediatric Infectious Diseases, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboudumc, 6525 GA Nijmegen, The Netherlands; Pediatric Infectious Diseases and Immunology, Department of Pediatrics, Radboudumc, 6525 GA Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2016.09.025DOI Listing
December 2016

Complement Factor H Serum Levels Determine Resistance to Pneumococcal Invasive Disease.

J Infect Dis 2016 06 21;213(11):1820-7. Epub 2016 Jan 21.

Laboratory of Pediatric Infectious Diseases Division of Pediatric Infectious Diseases and Immunology, Department of Pediatrics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/infdis/jiw029DOI Listing
June 2016

Protein-losing enteropathy in camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome.

Pediatr Rheumatol Online J 2016 May 25;14(1):32. Epub 2016 May 25.

Department of Paediatrics, Radboud University Nijmegen Medical Centre, Radboud umc. Geert Grooteplein Zuid 10, Nijmegen, 6525 GA, The Netherlands.

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http://dx.doi.org/10.1186/s12969-016-0093-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880819PMC
May 2016

Compound heterozygous mutations in the C6 gene of a child with recurrent infections.

Mol Immunol 2014 Apr 30;58(2):201-5. Epub 2013 Dec 30.

Department of Pediatric Infectious Diseases & Immunology (HP 804), Radboud University Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands; Nijmegen Institute for Infection, Immunity and Inflammation (HP 804), Radboud University Medical Centre, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2013.11.023DOI Listing
April 2014

Clinical spectrum of LIG4 deficiency is broadened with severe dysmaturity, primordial dwarfism, and neurological abnormalities.

Hum Mutat 2013 Dec 18;34(12):1611-4. Epub 2013 Sep 18.

Department of Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands; Department of Pediatrics, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/humu.22436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910166PMC
December 2013

Expression of human CEACAM1 in transgenic mice limits the Opa-specific immune response against meningococcal outer membrane vesicles.

Vaccine 2013 Nov 6;31(47):5585-93. Epub 2013 Aug 6.

Institute for Translational Vaccinology (InTraVacc), Antonie van Leeuwenhoeklaan 9, 3720 AL Bilthoven, The Netherlands; Department of Infectious Diseases and Immunology, Utrecht University, 3584 CL Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2013.07.069DOI Listing
November 2013

Decreased expression of serum and microvascular vascular endothelial growth factor receptor-2 in meningococcal sepsis*.

Pediatr Crit Care Med 2013 Sep;14(7):682-5

1Department of Pediatrics, Radboud University Medical Centre, Nijmegen, The Netherlands. 2The Nijmegen Institute for Infection, Inflammation, and Immunity, Radboud University Medical Centre, Nijmegen, The Netherlands. 3Department of Immunology, Erasmus Medical Centre, Rotterdam, The Netherlands. 4Department of Dermatology, Erasmus Medical Centre, Rotterdam, The Netherlands. 5Pediatric Intensive Care Unit, University Medical Centre Utrecht, Utrecht, The Netherlands. 6Department of Pediatric Infectious Diseases and Immunology, Erasmus Medical Centre, Rotterdam, The Netherlands. 7Pediatric Intensive Care Unit, Erasmus Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/PCC.0b013e3182917ccbDOI Listing
September 2013

Absolute lymphocyte count predicts the response to new influenza virus H1N1 vaccination in pediatric cancer patients.

Clin Vaccine Immunol 2013 Jan 21;20(1):118-21. Epub 2012 Nov 21.

Department of Pediatric Hematology and Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1128/CVI.00585-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535770PMC
January 2013

The comparison of the performance of two screening strategies identifying newly-diagnosed HIV during pregnancy.

Eur J Public Health 2011 Oct 4;21(5):632-7. Epub 2010 Nov 4.

Department of Obstetrics, Academic Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/eurpub/ckq157DOI Listing
October 2011

[Congenital toxoplasmosis: severe ocular and neurological complications].

Ned Tijdschr Geneeskd 2011 ;155(18):A2853

Canisius-Wilhelmina Ziekenhuis, Afd. Kindergeneeskunde, Nijmegen, the Netherlands.

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September 2011

Opa+ and Opa- isolates of Neisseria meningitidis and Neisseria gonorrhoeae induce sustained proliferative responses in human CD4+ T cells.

Infect Immun 2009 Nov 31;77(11):5170-80. Epub 2009 Aug 31.

Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1128/IAI.00355-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2772550PMC
November 2009

Fatal Aspergillus rhinosinusitis during induction chemotherapy in a child with acute lymphoblastic leukemia.

J Pediatr Hematol Oncol 2009 May;31(5):367-9

Department of Pediatrics, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1097/MPH.0b013e3181983c71DOI Listing
May 2009

Pharmacokinetics of lopinavir in HIV type-1-infected children taking the new tablet formulation once daily.

Antivir Ther 2008 ;13(8):1087-90

Department of Pediatric Infectious Diseases and Immunology, Erasmus Medical Centre, Sophia Children's Hospital, Rotterdam, The Netherlands.

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April 2009

Plasma vascular endothelial growth factor in severe sepsis.

Shock 2005 Jan;23(1):35-8

Wilhelmina Children's Hospital, University Medical Center, Utrecht, The Netherlands.

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http://dx.doi.org/10.1097/01.shk.0000150728.91155.41DOI Listing
January 2005

Intrathecal production and secretion of vascular endothelial growth factor during Cryptococcal Meningitis.

J Infect Dis 2004 Oct 18;190(7):1310-7. Epub 2004 Aug 18.

Department of Acute Medicine and Infectious Diseases and Eijkman-Winkler Institute for Microbiology, University Medical Center Utrecht, The Netherlands.

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http://dx.doi.org/10.1086/423849DOI Listing
October 2004

Vascular endothelial growth factor and blood-brain barrier disruption in tuberculous meningitis.

Pediatr Infect Dis J 2004 Jul;23(7):608-13

Eijkman-Winkler Institute, Department of Medicine, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1097/01.inf.0000131634.57368.45DOI Listing
July 2004