Publications by authors named "Michelle Lockley"

32Publications

Response to: A multicentre retrospective cohort study of ovarian germ cell tumours: Evidence for chemotherapy de-escalation and alignment of paediatric and adult practice.

Eur J Cancer 2020 May 18;130:267-268. Epub 2020 Mar 18.

Barts Health NHS Trust, West Smithfield, London, EC1A 7BE, UK; University College Hospital, 235 Euston Road London, NW1 2BU, UK; Barts Cancer Institute, CRUK Barts Cancer Centre, Queen Mary University London Charterhouse Square, London EC1M 6BQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2020.02.003DOI Listing
May 2020

Ovarian germ cell tumour classification: views from the testis.

Histopathology 2020 Jan;76(1):25-36

Centre for Molecular Oncology, Barts Cancer Institute, Charterhouse Square, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1111/his.14016DOI Listing
January 2020

Mainstreamed genetic testing in ovarian cancer: patient experience of the testing process.

Int J Gynecol Cancer 2020 02 19;30(2):221-226. Epub 2019 Nov 19.

Department of Women's Cancer, UCL Elizabeth Garrett Anderson Institution for Women's Health, University College London, London, UK

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http://dx.doi.org/10.1136/ijgc-2019-000630DOI Listing
February 2020

Ovarian cancer in adolescents and young adults.

Pediatr Blood Cancer 2019 03 23;66(3):e27512. Epub 2018 Oct 23.

Department of Paediatrics and Child Health, University College London Hospital, London, UK.

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http://dx.doi.org/10.1002/pbc.27512DOI Listing
March 2019

Mainstreamed genetic testing for women with ovarian cancer: first-year experience.

J Med Genet 2019 03 13;56(3):195-198. Epub 2018 Mar 13.

Wessex Clinical Genetics Service, University Hospitals Southampton, Southampton, UK.

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http://dx.doi.org/10.1136/jmedgenet-2017-105140DOI Listing
March 2019

Haemorrhagic shock due to spontaneous splenic rupture in a patient subsequently diagnosed with advanced ovarian cancer.

J Obstet Gynaecol 2017 Feb 6;37(2):268-270. Epub 2016 Dec 6.

a Gynaecological Oncology Department , Royal London Hospital , Barts Health NHS Trust , London , United Kingdom.

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http://dx.doi.org/10.1080/01443615.2016.1244811DOI Listing
February 2017

CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma.

Cancer Res 2016 10 16;76(20):6118-6129. Epub 2016 Aug 16.

Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom. Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802386PMC
October 2016

RAD51 and BRCA2 Enhance Oncolytic Adenovirus Type 5 Activity in Ovarian Cancer.

Mol Cancer Res 2016 Jan 9;14(1):44-55. Epub 2015 Oct 9.

Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom. Institute of Cancer Sciences, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.1158/1541-7786.MCR-15-0188-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716290PMC
January 2016

Chemotherapy Response Score: Development and Validation of a System to Quantify Histopathologic Response to Neoadjuvant Chemotherapy in Tubo-Ovarian High-Grade Serous Carcinoma.

J Clin Oncol 2015 Aug 29;33(22):2457-63. Epub 2015 Jun 29.

Steffen Böhm, Asma Faruqi, Ian Said, Michelle Lockley, Elly Brockbank, Arjun Jeyarajah, Amanda Fitzpatrick, and Naveena Singh, Barts Health National Health Service Trust; Steffen Böhm, Michelle Lockley, Darren Ennis, and Thomas Dowe, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom; Jennifer L. Santos, Anna V. Tinker, and Nhu D. Le, British Columbia Cancer Agency; C. Blake Gilks, University of British Columbia, Vancouver, BC, Canada; and Linda S. Cook, University of New Mexico, Albuquerque, NM.

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http://jco.ascopubs.org/content/early/2015/06/24/JCO.2014.60
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.60.5212
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http://dx.doi.org/10.1200/JCO.2014.60.5212DOI Listing
August 2015

Adaptive immunity in cancer immunology and therapeutics.

Ecancermedicalscience 2014 2;8:441. Epub 2014 Jul 2.

Barts Cancer Institute, Queen Mary University of London Charterhouse Square, London EC1M 6BQ, UK.

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http://dx.doi.org/10.3332/ecancer.2014.441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096025PMC
July 2014

Endothelial cell junctional adhesion molecule C plays a key role in the development of tumors in a murine model of ovarian cancer.

FASEB J 2013 Oct 3;27(10):4244-53. Epub 2013 Jul 3.

2Centre for Microvascular Research, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M6BQ, UK.

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http://dx.doi.org/10.1096/fj.13-230441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819510PMC
October 2013

The peritoneal tumour microenvironment of high-grade serous ovarian cancer.

J Pathol 2012 Jun 18;227(2):136-45. Epub 2012 Apr 18.

Barts Cancer Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M6BQ, UK.

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http://doi.wiley.com/10.1002/path.4002
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http://dx.doi.org/10.1002/path.4002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609073PMC
June 2012

Genomic DNA damage and ATR-Chk1 signaling determine oncolytic adenoviral efficacy in human ovarian cancer cells.

J Clin Invest 2011 Apr 7;121(4):1283-97. Epub 2011 Mar 7.

Centre for Molecular Oncology and Imaging, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.

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http://dx.doi.org/10.1172/JCI43976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069766PMC
April 2011

Inhibition of the inflammatory cytokine TNF-α increases adenovirus activity in ovarian cancer via modulation of cIAP1/2 expression.

Mol Ther 2011 Mar 16;19(3):490-9. Epub 2010 Nov 16.

Centres for Molecular Oncology and Imaging, Institute of Cancer, Barts and The London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1038/mt.2010.247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048177PMC
March 2011

p21 Promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker.

Mol Cancer 2010 Jul 3;9:175. Epub 2010 Jul 3.

Centre for Molecular Oncology and Imaging, Institute of Cancer, Barts and the London School of Medicine, Queen Mary University of London, London EC1 M 6BQ, UK.

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http://dx.doi.org/10.1186/1476-4598-9-175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904726PMC
July 2010

Quantifying the activity of adenoviral E1A CR2 deletion mutants using renilla luciferase bioluminescence and 3'-deoxy-3'-[18F]fluorothymidine positron emission tomography imaging.

Cancer Res 2006 Sep;66(18):9178-85

Molecular Therapy and PET Oncology Research Group, Clinical Sciences Centre, Imperial College School of Medicine, London, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-1539DOI Listing
September 2006

Activity of the adenoviral E1A deletion mutant dl922-947 in ovarian cancer: comparison with E1A wild-type viruses, bioluminescence monitoring, and intraperitoneal delivery in icodextrin.

Cancer Res 2006 Jan;66(2):989-98

Cancer Research UK Molecular Oncology Unit, Barts and the London School of Medicine, Charterhouse Square, London EC1M 6BQ, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-2691DOI Listing
January 2006