Michelle A Rudek

Michelle A Rudek

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Michelle A Rudek

Michelle A Rudek

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Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian Cancer.

ACS Omega 2018 Sep 27;3(9):11917-11929. Epub 2018 Sep 27.

Department of Oncology, Department of Pathology, and Department of Gynecology and Obstetrics, The Johns Hopkins University, Baltimore, Maryland 21231, United States.

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http://pubs.acs.org/doi/10.1021/acsomega.8b01479
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http://dx.doi.org/10.1021/acsomega.8b01479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166221PMC
September 2018

Combination antiretroviral therapy accelerates immune recovery in patients with HIV-related lymphoma treated with EPOCH: a comparison within one prospective trial AMC034.

Leuk Lymphoma 2018 08 21;59(8):1851-1860. Epub 2017 Nov 21.

e Department of Medicine , Memorial Sloan-Kettering Cancer Center/Weill-Cornell Medical College , New York , NY , USA.

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http://dx.doi.org/10.1080/10428194.2017.1403597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962410PMC
August 2018

Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer.

PLoS Negl Trop Dis 2018 08 13;12(8):e0006728. Epub 2018 Aug 13.

Department of Medicine, Johns Hopkins University Center for Tuberculosis Research, Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0006728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107292PMC
August 2018

Sorafenib Dose Recommendation in Acute Myeloid Leukemia Based on Exposure-FLT3 Relationship.

Clin Transl Sci 2018 07 27;11(4):435-443. Epub 2018 Apr 27.

Center for Translational Medicine, University of Maryland Baltimore, Maryland, USA.

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http://dx.doi.org/10.1111/cts.12555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039208PMC
July 2018

The effect of an adenosine A agonist on intra-tumoral concentrations of temozolomide in patients with recurrent glioblastoma.

Fluids Barriers CNS 2018 Jan 15;15(1). Epub 2018 Jan 15.

Brain Cancer Program, Johns Hopkins University, David H. Koch Cancer Research Building II, 1550 Orleans Street, Room 1M16, Baltimore, MD, 21287, USA.

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http://dx.doi.org/10.1186/s12987-017-0088-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5767971PMC
January 2018

Modernizing Clinical Trial Eligibility Criteria: Recommendations of the American Society of Clinical Oncology-Friends of Cancer Research HIV Working Group.

J Clin Oncol 2017 Nov 2;35(33):3774-3780. Epub 2017 Oct 2.

Thomas S. Uldrick and Richard F. Little, National Cancer Institute, Bethesda; Gwynn Ison and Barry Miller, US Food and Drug Administration, Silver Spring; Michelle A. Rudek, Johns Hopkins University, Baltimore, MD; Ariela Noy, Memorial Sloan Kettering Cancer Center and Weill Medical College, New York, NY; Karl Schwartz, Patients Against Lymphoma, Riegelsville, PA; Suanna Bruinooge and Caroline Schenkel, ASCO, Alexandria, VA; Kieron Dunleavy, George Washington University, Washington, DC; Judy Wang, Florida Cancer Specialists and Research Institute, Sarasota, FL; and Jerome Zeldis, Sorrento Therapeutics, San Diego, CA.

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http://dx.doi.org/10.1200/JCO.2017.73.7338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793223PMC
November 2017

Adaptation to TKI Treatment Reactivates ERK Signaling in Tyrosine Kinase-Driven Leukemias and Other Malignancies.

Cancer Res 2017 10 18;77(20):5554-5563. Epub 2017 Sep 18.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819342PMC
October 2017

Entinostat: a promising treatment option for patients with advanced breast cancer.

Future Oncol 2017 Jun 9;13(13):1137-1148. Epub 2017 Mar 9.

Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.2217/fon-2016-0526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618943PMC
June 2017

Metformin Protects Cells from Mutant Huntingtin Toxicity Through Activation of AMPK and Modulation of Mitochondrial Dynamics.

Neuromolecular Med 2016 Dec 25;18(4):581-592. Epub 2016 May 25.

Division of Neurobiology, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 North Wolfe Street, CMSC 8-121, Baltimore, MD, 21287, USA.

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http://dx.doi.org/10.1007/s12017-016-8412-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112128PMC
December 2016

The Effect of Hepatic Impairment on Outcomes in Phase I Clinical Trials in Cancer Subjects.

Clin Cancer Res 2016 Nov 17;22(22):5472-5479. Epub 2016 May 17.

Investigational Drug Branch, Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, Maryland.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-0449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114163PMC
November 2016

Simultaneous quantitative determination of 5-aza-2'-deoxycytidine genomic incorporation and DNA demethylation by liquid chromatography tandem mass spectrometry as exposure-response measures of nucleoside analog DNA methyltransferase inhibitors.

J Chromatogr B Analyt Technol Biomed Life Sci 2016 Jun 21;1022:38-45. Epub 2016 Mar 21.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA; Department of Oncology, School of Medicine, Johns Hopkins University, 1650 Orleans Street, Baltimore, MD, 21231 USA; Division of Clinical Pharmacology, Department of Medicine, School of Medicine, Johns Hopkins University, 1650 Orleans Street, Baltimore, MD, 21231 USA. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2016.03.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866886PMC
June 2016

Brief Report: A Phase 1b/Pharmacokinetic Trial of PTC299, a Novel PostTranscriptional VEGF Inhibitor, for AIDS-Related Kaposi's Sarcoma: AIDS Malignancy Consortium Trial 059.

J Acquir Immune Defic Syndr 2016 May;72(1):52-7

*Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, WA;†Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center, Seattle, WA;‡Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR;§The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD;‖Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC;¶Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC; and#Division of Medical Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1097/QAI.0000000000000918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838493PMC
May 2016

Corrigendum to "Quantification of 5-azacytidine in plasma by electrospray tandem mass spectrometry coupled with high-performance liquid chromatography" [J. Chromatogr. B 813(1) (2004) 81-88].

J Chromatogr B Analyt Technol Biomed Life Sci 2016 May 25;1020:167. Epub 2016 Mar 25.

Division of Experimental Therapeutics, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Bunting-Blaustein Cancer Research Building, 1650 Orleans Street, Room 1M87, Baltimore, MD 21231, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2016.03.018DOI Listing
May 2016

A robust and rapid liquid chromatography tandem mass spectrometric method for the quantitative analysis of 5-azacytidine.

Biomed Chromatogr 2016 Mar 17;30(3):494-6. Epub 2015 Aug 17.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/bmc.3562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713385PMC
March 2016

The effect of regadenoson-induced transient disruption of the blood-brain barrier on temozolomide delivery to normal rat brain.

J Neurooncol 2016 Feb 1;126(3):433-9. Epub 2015 Dec 1.

Brain Cancer Program, Johns Hopkins University, David H. Koch Cancer Research Building II, 1550 Orleans Street, Room 1M16, Baltimore, MD, 21287, USA.

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http://dx.doi.org/10.1007/s11060-015-1998-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733584PMC
February 2016

Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs.

Oncotarget 2016 Feb;7(6):7268-79

Center for Stem Cell Biology & Regenerative Medicine, Departments of Pediatrics and Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.18632/oncotarget.6896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872784PMC
February 2016

Human hepatocyte assessment of imatinib drug-drug interactions - complexities in clinical translation.

Br J Clin Pharmacol 2015 Nov 19;80(5):1097-108. Epub 2015 Sep 19.

Department of Pharmaceutical Sciences, School of Pharmacy, Pittsburgh, PA.

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http://dx.doi.org/10.1111/bcp.12723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631182PMC
November 2015

Preclinical assessment of the interactions between the antiretroviral drugs, ritonavir and efavirenz, and the tyrosine kinase inhibitor erlotinib.

Cancer Chemother Pharmacol 2015 Oct 2;76(4):813-9. Epub 2015 Sep 2.

The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 1650 Orleans Street, Bunting-Blaustein Cancer Research Bldg. Room 1M52, Baltimore, MD, 21231-1000, USA.

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http://link.springer.com/content/pdf/10.1007%2Fs00280-015-28
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http://link.springer.com/10.1007/s00280-015-2856-y
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http://dx.doi.org/10.1007/s00280-015-2856-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577782PMC
October 2015

Brain Penetration and Efficacy of Different Mebendazole Polymorphs in a Mouse Brain Tumor Model.

Clin Cancer Res 2015 Aug 10;21(15):3462-3470. Epub 2015 Apr 10.

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526400PMC
August 2015

Targeting DDX3 with a small molecule inhibitor for lung cancer therapy.

EMBO Mol Med 2015 May;7(5):648-69

Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

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http://dx.doi.org/10.15252/emmm.201404368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492822PMC
May 2015

Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma.

Neuro Oncol 2015 Jan 22;17(1):70-80. Epub 2014 Jul 22.

Department of Neurosurgery (R.T.W., J.A., A.M., I.Z., L.H., A.J., H.B., M.H.-C., K.L.M., H.B., B.M.T.); Departments of Oncology, Ophthalmology, and Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland (H.B.); Division of Chemical Therapeutics, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland (M.A.R., M.Z.).

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http://dx.doi.org/10.1093/neuonc/nou143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483048PMC
January 2015

Potential interactions between HIV drugs, ritonavir and efavirenz and anticancer drug, nilotinib--a study in primary cultures of human hepatocytes that is applicable to HIV patients with cancer.

J Clin Pharmacol 2014 Nov 27;54(11):1272-9. Epub 2014 May 27.

Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1002/jcph.333DOI Listing
November 2014

A phase II study of the gamma secretase inhibitor RO4929097 in patients with previously treated metastatic pancreatic adenocarcinoma.

Invest New Drugs 2014 Aug 27;32(4):739-45. Epub 2014 Mar 27.

Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 1650 Orleans St. CRB1-4M08, Baltimore, MD, 21287, USA,

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http://dx.doi.org/10.1007/s10637-014-0083-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292847PMC
August 2014

Combination antiretroviral therapy (cART) component ritonavir significantly alters docetaxel exposure.

Cancer Chemother Pharmacol 2014 Apr 2;73(4):729-36. Epub 2014 Feb 2.

The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 1650 Orleans Street, Room 1M52, Baltimore, MD, 21231-1000, USA,

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http://dx.doi.org/10.1007/s00280-014-2399-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968228PMC
April 2014

Phase II trial of imatinib in AIDS-associated Kaposi's sarcoma: AIDS Malignancy Consortium Protocol 042.

J Clin Oncol 2014 Feb 30;32(5):402-8. Epub 2013 Dec 30.

Henry B. Koon and Zhenghe Wang, Case Comprehensive Cancer Center, Case Western Reserve University; Kord Honda, University Hospitals; Cleveland, OH; Susan E. Krown, Ariela Noy, Memorial Sloan-Kettering Cancer Center, New York, NY; Jeannette Y. Lee, University of Arkansas for Medical Sciences, Little Rock, AR; Suthee Rapisuwon, Georgetown University Medical Center, Washington, DC; David Aboulafia, Virginia Mason Medical Center, Seattle, WA; Erin G. Reid, University of California San Diego Moores Cancer Center, San Diego, CA; Michelle A. Rudek, Johns Hopkins University, Baltimore, MD; Bruce J Dezube, Beth Israel Deaconess Medical Center, Boston, MA.

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http://dx.doi.org/10.1200/JCO.2012.48.6365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912327PMC
February 2014

Bioanalytical method for evaluating the pharmacokinetics of the GCP-II inhibitor 2-phosphonomethyl pentanedioic acid (2-PMPA).

J Pharm Biomed Anal 2014 Jan 30;88:162-9. Epub 2013 Aug 30.

Brain Science Institute, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.jpba.2013.08.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891469PMC
January 2014

A targeting modality for destruction of RNA polymerase I that possesses anticancer activity.

Cancer Cell 2014 Jan;25(1):77-90

Molecular Cancer Biology Program and Centre for Drug Research, University of Helsinki, Helsinki 00014, Finland; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA; Department of Oncology and The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2013.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930145PMC
January 2014

A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer.

Cancer Cell 2013 Dec;24(6):791-805

Department of Oncology, The Johns Hopkins University, Baltimore, MD 21231, USA; Department of Pathology, The Johns Hopkins University, Baltimore, MD 21231, USA; Department of Gynecology and Obstetrics, The Johns Hopkins University, Baltimore, MD 21231, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2013.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881268PMC
December 2013

A glutamate receptor antagonist, S-4-carboxyphenylglycine (S-4-CPG), inhibits vasospasm after subarachnoid hemorrhage in haptoglobin 2-2 mice [corrected].

Neurosurgery 2013 Oct;73(4):719-28; discussion 729

Department of †Neurosurgery; ‡Oncology Center-Chemical Therapeutics, The Johns Hopkins University School of Medicine, Baltimore, Maryland; §Technion Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

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http://dx.doi.org/10.1227/NEU.0000000000000080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461079PMC
October 2013

Ritonavir and efavirenz significantly alter the metabolism of erlotinib--an observation in primary cultures of human hepatocytes that is relevant to HIV patients with cancer.

Drug Metab Dispos 2013 Oct 2;41(10):1843-51. Epub 2013 Aug 2.

Department of Pharmaceutical Sciences and Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania (V.C.P., R.V.); Molecular Therapeutics Drug Discovery program, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania (R.A.P., S.M.C., J.H.B.); Division of Pathology, Department of Laboratory Medicine, Karolinska Institutet and Hospital, Stockholm, Sweden (R.G., S.C.S.); and The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland (M.A.R.).

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http://dx.doi.org/10.1124/dmd.113.052100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781374PMC
October 2013

Thioridazine lacks bactericidal activity in an animal model of extracellular tuberculosis.

J Antimicrob Chemother 2013 Jun 5;68(6):1327-30. Epub 2013 Mar 5.

Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1093/jac/dkt037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654222PMC
June 2013

Phase I pharmacokinetic and pharmacodynamic study of cetuximab, irinotecan and sorafenib in advanced colorectal cancer.

Invest New Drugs 2013 Apr 22;31(2):345-54. Epub 2012 May 22.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Bunting-Blaustein Cancer Research Bldg, Room 1M52, 1650 Orleans Street, Baltimore, MD 21231-1000, USA.

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http://dx.doi.org/10.1007/s10637-012-9820-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674958PMC
April 2013

Plasma protein binding of sorafenib, a multi kinase inhibitor: in vitro and in cancer patients.

Invest New Drugs 2012 Dec 17;30(6):2096-102. Epub 2011 Nov 17.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Bunting-Blaustein Cancer Research Bldg, Room 1M52, Baltimore, MD 21231-1000, USA.

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http://dx.doi.org/10.1007/s10637-011-9767-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652000PMC
December 2012

Integrated preclinical and clinical development of S-trans, trans-Farnesylthiosalicylic Acid (FTS, Salirasib) in pancreatic cancer.

Invest New Drugs 2012 Dec 1;30(6):2391-9. Epub 2012 May 1.

Department of Medical Oncology, Skip Viragh Center for Pancreatic Cancer Research and Patient Care, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Bunting- Blaustein Cancer Research Building, Room 4M09, Baltimore, MD 21231, USA.

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http://link.springer.com/10.1007/s10637-012-9818-6
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http://dx.doi.org/10.1007/s10637-012-9818-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557459PMC
December 2012

Reversible disulfide formation of the glutamate carboxypeptidase II inhibitor E2072 results in prolonged systemic exposures in vivo.

Drug Metab Dispos 2012 Dec 4;40(12):2315-23. Epub 2012 Sep 4.

NeuroTranslational Drug Discovery Program, Brain Science Institute, Johns Hopkins School of Medicine, Baltimore, MD, USA.

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http://dmd.aspetjournals.org/cgi/doi/10.1124/dmd.112.046821
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http://dx.doi.org/10.1124/dmd.112.046821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500546PMC
December 2012

The rising challenge of non-AIDS-defining cancers in HIV-infected patients.

Clin Infect Dis 2012 Nov 9;55(9):1228-35. Epub 2012 Jul 9.

Division of Hematology/Oncology, Georgetown University Medical Center, 3800 Reservoir Rd NW, Washington, DC 20007, USA.

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http://dx.doi.org/10.1093/cid/cis613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529613PMC
November 2012

The impact of bevacizumab on temozolomide concentrations in intracranial U87 gliomas.

Cancer Chemother Pharmacol 2012 Jul 27;70(1):129-39. Epub 2012 May 27.

Department of Neurosurgery, Tel-Aviv Medical Center, Tel Aviv, Israel.

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http://dx.doi.org/10.1007/s00280-012-1867-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4005329PMC
July 2012

Phase I and pharmacokinetic study of COL-3 in patients with recurrent high-grade gliomas.

J Neurooncol 2011 Nov 6;105(2):375-81. Epub 2011 May 6.

Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1007/s11060-011-0602-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197967PMC
November 2011

Bisphosphonamidate clodronate prodrug exhibits potent anticancer activity in non-small-cell lung cancer cells.

J Med Chem 2011 Oct 9;54(19):6647-56. Epub 2011 Sep 9.

Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, WBSB 305, Baltimore, Maryland 21201, United States.

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http://dx.doi.org/10.1021/jm200521aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188694PMC
October 2011

The optimal dose of prophylactic intravenous naloxone in ameliorating opioid-induced side effects in children receiving intravenous patient-controlled analgesia morphine for moderate to severe pain: a dose finding study.

Anesth Analg 2011 Oct 2;113(4):834-42. Epub 2011 Sep 2.

Department of Anesthesiology and Critical Care Medicine, Division of Pediatric Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, 600 North Wolfe St., Blalock 904, Baltimore, MD 21287, USA.

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https://insights.ovid.com/crossref?an=00000539-201110000-000
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461032PMC
http://dx.doi.org/10.1213/ANE.0b013e31822c9a44DOI Listing
October 2011

Use of antineoplastic agents in patients with cancer who have HIV/AIDS.

Lancet Oncol 2011 Sep 12;12(9):905-12. Epub 2011 May 12.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1016/S1470-2045(11)70056-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3343721PMC
September 2011

Quantitation of sorafenib and its active metabolite sorafenib N-oxide in human plasma by liquid chromatography-tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2010 Nov 9;878(29):3033-8. Epub 2010 Sep 9.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15700232100055
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http://dx.doi.org/10.1016/j.jchromb.2010.08.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2956857PMC
November 2010

Castration-dependent pharmacokinetics of docetaxel in patients with prostate cancer.

J Clin Oncol 2010 Oct 20;28(30):4562-7. Epub 2010 Sep 20.

St Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1200/JCO.2010.30.7025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974340PMC
October 2010