Micheline Kirsch-Volders

Micheline Kirsch-Volders

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Micheline Kirsch-Volders

Publications by authors named "Micheline Kirsch-Volders"

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Validity of the Lymphocyte Cytokinesis-Block Micronucleus Assay (L-CBMN) as biomarker for human exposure to chemicals with different modes of action: A synthesis of systematic reviews.

Mutat Res Genet Toxicol Environ Mutagen 2018 Dec 7;836(Pt A):47-52. Epub 2018 May 7.

Environmental Carcinogenesis Unit, Ospedale Policlinico San Martino, L.go Rosanna Benzi, 10 16132, Genova, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13835718183001
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http://dx.doi.org/10.1016/j.mrgentox.2018.05.010DOI Listing
December 2018

The lymphocyte cytokinesis block micronucleus test in human populations occupationally exposed to vinyl chloride: A systematic review and meta-analysis.

Mutat Res 2017 10 31;774:1-11. Epub 2017 Jul 31.

Laboratory for Cell Genetics, Faculty of Sciences and Bioengineering, Vrije Universiteit Brussel, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.mrrev.2017.07.003DOI Listing
October 2017

Towards a New Paradigm in Nano-Genotoxicology: Facing Complexity of Nanomaterials' Cellular Interactions and Effects.

Basic Clin Pharmacol Toxicol 2017 Sep 15;121 Suppl 3:23-29. Epub 2017 Mar 15.

Laboratory of Cell Genetics, Free University of Brussels (VUB), Brussels, Belgium.

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http://dx.doi.org/10.1111/bcpt.12698DOI Listing
September 2017

Biomonitoring of genotoxic effects for human exposure to nanomaterials: The challenge ahead.

Mutat Res Rev Mutat Res 2016 Apr-Jun;768:14-26. Epub 2016 Mar 4.

Laboratory of Cell Genetics, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.mrrev.2016.03.002DOI Listing
July 2017

Epigenetic memory in response to environmental stressors.

FASEB J 2017 06 9;31(6):2241-2251. Epub 2017 Mar 9.

Institute of Biology, Medicinal Chemistry, and Biotechnology, National Hellenic Research Foundation, Athens, Greece.

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http://dx.doi.org/10.1096/fj.201601059RRDOI Listing
June 2017

Molecular mechanisms by which in vivo exposure to exogenous chemical genotoxic agents can lead to micronucleus formation in lymphocytes in vivo and ex vivo in humans.

Mutat Res 2016 Oct - Dec;770(Pt A):12-25. Epub 2016 Jun 7.

Laboratory of Cell Genetics, Faculty of Science and Bio-Engineering, Free University of Brussels (VUB), Pleinlaan 2, 1050 Brussel, Belgium.

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http://dx.doi.org/10.1016/j.mrrev.2016.04.008DOI Listing
May 2017

Reprint of "Biomonitoring of genotoxic effects for human exposure to nanomaterials: The challenge ahead".

Mutat Res 2016 Oct - Dec;770(Pt A):204-216. Epub 2016 Nov 16.

Laboratory of Cell Genetics, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.mrrev.2016.11.001DOI Listing
May 2017

The ex vivo L-CBMN assay detects significant human exposure to butadiene.

Mutat Res 2016 Oct - Dec;770(Pt A):73-83. Epub 2016 Apr 6.

Laboratory for Cell Genetics, Faculty of Sciences and Bioengineering, Vrije Universiteit Brussel, Brussels, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.mrrev.2016.04.001DOI Listing
May 2017

Amorphous silica nanoparticles alter microtubule dynamics and cell migration.

Nanotoxicology 2015 17;9(6):729-36. Epub 2014 Oct 17.

Laboratory of Cell Genetics, Vrije Universiteit Brussel , Brussels , Belgium .

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http://dx.doi.org/10.3109/17435390.2014.969791DOI Listing
April 2016

Micronucleus frequency in Danish schoolchildren and their mothers from the DEMOCOPHES population.

Mutagenesis 2016 Jan 17;31(1):1-8. Epub 2015 Jul 17.

Laboratory of Cell Genetics), Faculty of Science and Bio-Engineering, Free University of Brussels (VUB), Pleinlaan 2, 1050 Brussel, Belgium.

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http://dx.doi.org/10.1093/mutage/gev054DOI Listing
January 2016

Outdoor air pollution exposures and micronuclei frequencies in lymphocytes from pregnant women and newborns in Crete, Greece (Rhea cohort).

Environ Res 2015 Nov 21;143(Pt A):170-6. Epub 2015 Oct 21.

Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.

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http://dx.doi.org/10.1016/j.envres.2015.10.011DOI Listing
November 2015

Morphological observation of embryoid bodies completes the in vitro evaluation of nanomaterial embryotoxicity in the embryonic stem cell test (EST).

Toxicol In Vitro 2015 Oct 17;29(7):1587-96. Epub 2015 Jun 17.

Laboratory of Cell Genetics, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussel, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.tiv.2015.06.015DOI Listing
October 2015

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Authors:
William H Goodson Leroy Lowe David O Carpenter Michael Gilbertson Abdul Manaf Ali Adela Lopez de Cerain Salsamendi Ahmed Lasfar Amancio Carnero Amaya Azqueta Amedeo Amedei Amelia K Charles Andrew R Collins Andrew Ward Anna C Salzberg Annamaria Colacci Ann-Karin Olsen Arthur Berg Barry J Barclay Binhua P Zhou Carmen Blanco-Aparicio Carolyn J Baglole Chenfang Dong Chiara Mondello Chia-Wen Hsu Christian C Naus Clement Yedjou Colleen S Curran Dale W Laird Daniel C Koch Danielle J Carlin Dean W Felsher Debasish Roy Dustin G Brown Edward Ratovitski Elizabeth P Ryan Emanuela Corsini Emilio Rojas Eun-Yi Moon Ezio Laconi Fabio Marongiu Fahd Al-Mulla Ferdinando Chiaradonna Firouz Darroudi Francis L Martin Frederik J Van Schooten Gary S Goldberg Gerard Wagemaker Gladys N Nangami Gloria M Calaf Graeme Williams Gregory T Wolf Gudrun Koppen Gunnar Brunborg H Kim Lyerly Harini Krishnan Hasiah Ab Hamid Hemad Yasaei Hideko Sone Hiroshi Kondoh Hosni K Salem Hsue-Yin Hsu Hyun Ho Park Igor Koturbash Isabelle R Miousse A Ivana Scovassi James E Klaunig Jan Vondráček Jayadev Raju Jesse Roman John Pierce Wise Jonathan R Whitfield Jordan Woodrick Joseph A Christopher Josiah Ochieng Juan Fernando Martinez-Leal Judith Weisz Julia Kravchenko Jun Sun Kalan R Prudhomme Kannan Badri Narayanan Karine A Cohen-Solal Kim Moorwood Laetitia Gonzalez Laura Soucek Le Jian Leandro S D'Abronzo Liang-Tzung Lin Lin Li Linda Gulliver Lisa J McCawley Lorenzo Memeo Louis Vermeulen Luc Leyns Luoping Zhang Mahara Valverde Mahin Khatami Maria Fiammetta Romano Marion Chapellier Marc A Williams Mark Wade Masoud H Manjili Matilde E Lleonart Menghang Xia Michael J Gonzalez Michalis V Karamouzis Micheline Kirsch-Volders Monica Vaccari Nancy B Kuemmerle Neetu Singh Nichola Cruickshanks Nicole Kleinstreuer Nik van Larebeke Nuzhat Ahmed Olugbemiga Ogunkua P K Krishnakumar Pankaj Vadgama Paola A Marignani Paramita M Ghosh Patricia Ostrosky-Wegman Patricia A Thompson Paul Dent Petr Heneberg Philippa Darbre Po Sing Leung Pratima Nangia-Makker Qiang Shawn Cheng R Brooks Robey Rabeah Al-Temaimi Rabindra Roy Rafaela Andrade-Vieira Ranjeet K Sinha Rekha Mehta Renza Vento Riccardo Di Fiore Richard Ponce-Cusi Rita Dornetshuber-Fleiss Rita Nahta Robert C Castellino Roberta Palorini Roslida Abd Hamid Sabine A S Langie Sakina E Eltom Samira A Brooks Sandra Ryeom Sandra S Wise Sarah N Bay Shelley A Harris Silvana Papagerakis Simona Romano Sofia Pavanello Staffan Eriksson Stefano Forte Stephanie C Casey Sudjit Luanpitpong Tae-Jin Lee Takemi Otsuki Tao Chen Thierry Massfelder Thomas Sanderson Tiziana Guarnieri Tove Hultman Valérian Dormoy Valerie Odero-Marah Venkata Sabbisetti Veronique Maguer-Satta W Kimryn Rathmell Wilhelm Engström William K Decker William H Bisson Yon Rojanasakul Yunus Luqmani Zhenbang Chen Zhiwei Hu

Carcinogenesis 2015 Jun;36 Suppl 1:S254-96

Department of Surgery, The Ohio State University College of Medicine, The James Comprehensive Cancer Center, Columbus, OH 43210, USA.

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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://www.ilcambiamento.it/files/carcinogenesi.pdf
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http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
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http://dx.doi.org/10.1093/carcin/bgv039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480130PMC
June 2015

The effect of dietary estimates calculated using food frequency questionnaires on micronuclei formation in European pregnant women: a NewGeneris study.

Mutagenesis 2014 Nov 8;29(6):393-400. Epub 2014 Oct 8.

Laboratory of Cell Genetics, Faculty of Science and Bio-engineering, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium, National Hellenic Research Foundation, Institute of Biology, Medicinal Chemistry and Biotechnology, Vassileos Constantinou Avenue 48, 11635 Athens, Greece, Division of Medical Science, School of Life Science, University of Bradford, Bradford, West Yorkshire, BD7 1DP, UK, Department of Histology and Department of Social Medicine, School of Medicine, University of Crete, PO Box 2208, 71003 Heraklion, Greece, Centre for Research in Environmental Epidemiology (CREAL), Dr. Aiguader 88, 08003 Barcelona, Spain, Grup de Mutagenesi, Departament de Genetica i de Microbiologia, Universitat Autonoma de Barcelona, Placa Civica, 08193 Cerdanyola del Vallès, Ellaterra, Spain, Hospital del Mar Medical Research Institute, Dr. Aiguader 88, 08003 Barcelona, Spain, Division of Environmental Medicine, Norwegian Institute of Public Health, PO Box 4404 Nydalen, 0403 Oslo, Norway, Department of Public Health, University of Copenhagen, Norregade 10, 1165 Copenhagen, Denmark, Laboratory of Antropogenetics, Faculty of Science and Bio-engineering, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium, Epidemiology, Biostatistics, and Clinical Trials, IRCCS AOU San Martino-IST-National Cancer Research Institute, R. Benzi 10, 16132 Genoa, Italy, Department of Toxicogenomics, University of Maastricht, Minderbroedersberg 4-6, 6211 LK Maastricht, the Netherlands, Municipal Institute of Medical Research, Dr. Aiguader 88, 08003 Barcelona, Spain, CIBER Epidemiologia y Salud Pública (CIBERESP), Casanova 143, 08036 Barcelona, Spain and National School of Public Health, Alexandras Avenue 196, 11521 Athens, Greece.

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http://dx.doi.org/10.1093/mutage/geu052DOI Listing
November 2014

Benzo[a]pyrene-induced cell cycle arrest in HepG2 cells is associated with delayed induction of mitotic instability.

Mutat Res 2014 Nov 19;769:59-68. Epub 2014 Jul 19.

Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation, Athens, Greece.

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http://dx.doi.org/10.1016/j.mrfmmm.2014.07.004DOI Listing
November 2014

Fluorescence in situ hybridization (FISH) technique for the micronucleus test.

Methods Mol Biol 2013 ;1044:237-44

Laboratorium voor Cellulaire Genetica, Vrije Universiteit Brussel, Brussels, Belgium.

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http://dx.doi.org/10.1007/978-1-62703-529-3_12DOI Listing
February 2014

Micronuclei in cord blood lymphocytes and associations with biomarkers of exposure to carcinogens and hormonally active factors, gene polymorphisms, and gene expression: the NewGeneris cohort.

Environ Health Perspect 2014 Feb 19;122(2):193-200. Epub 2013 Nov 19.

Epidemiology, Biostatistics, and Clinical Trials, Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Azienda Ospedaliera Universitaria (AOU) San Martino-Istituto Nazionale per la Ricerca sul Cancro (IST), Genoa, Italy.

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http://ehp.niehs.nih.gov/wp-content/uploads/121/11/ehp.12063
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http://ehp.niehs.nih.gov/1206324
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http://dx.doi.org/10.1289/ehp.1206324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3914866PMC
February 2014

Lower nucleotide excision repair capacity in newborns compared to their mothers: a pilot study.

Reprod Toxicol 2014 Jan 20;43:67-71. Epub 2013 Nov 20.

Laboratory of Cell Genetics, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussel, Belgium.

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http://dx.doi.org/10.1016/j.reprotox.2013.11.002DOI Listing
January 2014

Hard-metal (WC-Co) particles trigger a signaling cascade involving p38 MAPK, HIF-1α, HMOX1, and p53 activation in human PBMC.

Arch Toxicol 2013 Feb 28;87(2):259-68. Epub 2012 Sep 28.

Laboratorium voor Cellulaire Genetica, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussel, Belgium.

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http://link.springer.com/10.1007/s00204-012-0943-y
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http://dx.doi.org/10.1007/s00204-012-0943-yDOI Listing
February 2013

Preterm newborns show slower repair of oxidative damage and paternal smoking associated DNA damage.

Mutagenesis 2012 Sep 2;27(5):573-80. Epub 2012 May 2.

Laboratory of Cell Genetics, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussel, Belgium.

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http://dx.doi.org/10.1093/mutage/ges022DOI Listing
September 2012

Assessment of side-effects by Ludox TMA silica nanoparticles following a dietary exposure on the bumblebee Bombus terrestris.

Nanotoxicology 2012 Aug 15;6(5):554-61. Epub 2011 Jun 15.

Laboratory of Cellular Genetics, Department of Biology, Faculty of Science and Bioengineering Sciences, Free University of Brussels, Brussels, Belgium.

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http://dx.doi.org/10.3109/17435390.2011.590905DOI Listing
August 2012

Miniaturized flow cytometry-based in vitro primary human lymphocyte micronucleus assay-validation study.

Environ Mol Mutagen 2012 May 19;53(4):260-70. Epub 2012 Mar 19.

Genetic toxicology and Safety Pharmacology, Preclinical Safety, Novartis Institutes for Biomedical Research, Basel, Switzerland.

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http://doi.wiley.com/10.1002/em.21690
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http://dx.doi.org/10.1002/em.21690DOI Listing
May 2012

Oxidative stress induced by pure and iron-doped amorphous silica nanoparticles in subtoxic conditions.

Chem Res Toxicol 2012 Apr 13;25(4):828-37. Epub 2012 Mar 13.

Unit for Lung Toxicology, Katholieke Universiteit Leuven, Herestraat 49, O&N1-706, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1021/tx200361vDOI Listing
April 2012

Cytogenetic methods in human biomonitoring: principles and uses.

Methods Mol Biol 2012 ;817:305-34

Vrije Universiteit Brussel, Brussels, Belgium.

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http://dx.doi.org/10.1007/978-1-61779-421-6_15DOI Listing
March 2012

In vitro primary human lymphocyte flow cytometry based micronucleus assay: simultaneous assessment of cell proliferation, apoptosis and MN frequency.

Mutagenesis 2011 Nov 26;26(6):763-70. Epub 2011 Jul 26.

Genetic Toxicology and Safety Pharmacology, Preclinical Safety, Novartis Institutes for Biomedical Research, Werk Klybeck, Klybeckstrasse 141, CH-4057 Basel, Switzerland.

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http://dx.doi.org/10.1093/mutage/ger044DOI Listing
November 2011

Maternal and gestational factors and micronucleus frequencies in umbilical blood: the NewGeneris Rhea cohort in Crete.

Environ Health Perspect 2011 Oct 27;119(10):1460-5. Epub 2011 May 27.

Laboratory of Cell Genetics, Faculty of Science and Bio-engineering, Vrije Universiteit Brussel, Brussels, Belgium.

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http://dx.doi.org/10.1289/ehp.1003246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3230441PMC
October 2011

STrengthening the reporting of OBservational studies in Epidemiology-Molecular Epidemiology (STROBE-ME): an extension of the STROBE statement.

Eur J Epidemiol 2011 Oct 29;26(10):797-810. Epub 2011 Oct 29.

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St Mary's Campus Norfolk Place, W2 1PG London, UK.

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http://dx.doi.org/10.1007/s10654-011-9622-1DOI Listing
October 2011

The in vitro MN assay in 2011: origin and fate, biological significance, protocols, high throughput methodologies and toxicological relevance.

Arch Toxicol 2011 Aug 3;85(8):873-99. Epub 2011 May 3.

Laboratorium voor Cellulaire Genetica, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.

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http://dx.doi.org/10.1007/s00204-011-0691-4DOI Listing
August 2011

A flow cytometry based in vitro micronucleus assay in TK6 cells--validation using early stage pharmaceutical development compounds.

Environ Mol Mutagen 2011 Jun 20;52(5):363-72. Epub 2010 Oct 20.

Novartis Institutes for Biomedical Research, Preclinical Safety, Genetic Toxicology and Safety Pharmacology, Basel, Switzerland.

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http://dx.doi.org/10.1002/em.20632DOI Listing
June 2011

Micronucleus assay and labeling of centromeres with FISH technique.

Methods Mol Biol 2011 ;691:115-36

Laboratorium voor Cellulaire Genetica, Vrije Universiteit Brussel, Brussels, Belgium.

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http://dx.doi.org/10.1007/978-1-60761-849-2_7DOI Listing
February 2011

Methodological approaches influencing cellular uptake and cyto-(geno) toxic effects of nanoparticles.

J Biomed Nanotechnol 2011 Feb;7(1):3-5

Laboratory for Cellular Genetics, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.

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http://dx.doi.org/10.1166/jbn.2011.1172DOI Listing
February 2011

Genetic polymorphisms of genes involved in DNA repair and metabolism influence micronucleus frequencies in human peripheral blood lymphocytes.

Mutagenesis 2011 Jan;26(1):33-42

CSIRO Food and Nutritional Sciences, Gate 13, Kintore Avenue, PO Box 10041, Adelaide, South Australia 5000, Australia.

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http://dx.doi.org/10.1093/mutage/geq076DOI Listing
January 2011

Automated image analysis of micronuclei by IMSTAR for biomonitoring.

Mutagenesis 2011 Jan;26(1):163-8

Laboratorium voor Cellulaire Genetica, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.

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http://dx.doi.org/10.1093/mutage/geq063DOI Listing
January 2011

In vitro genotoxicity testing using the micronucleus assay in cell lines, human lymphocytes and 3D human skin models.

Mutagenesis 2011 Jan;26(1):177-84

Laboratorium voor Cellulaire Genetica, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.

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http://dx.doi.org/10.1093/mutage/geq068DOI Listing
January 2011

Potential thresholds for genotoxic effects by micronucleus scoring.

Mutagenesis 2011 Jan;26(1):199-204

Novartis Institutes for Biomedical Research, Translational Sciences, Preclinical Safety, Genetic Toxicology and Safety Pharmacology, Klybeckstrasse 141, CH-4057 Basel, Switzerland.

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http://dx.doi.org/10.1093/mutage/geq089DOI Listing
January 2011

The HUMN and HUMNxL international collaboration projects on human micronucleus assays in lymphocytes and buccal cells--past, present and future.

Mutagenesis 2011 Jan;26(1):239-45

Department of Nutritional Genomics and DNA Damage Diagnostics, Commonwealth Scientific and Industrial Research Organisation Food and Nutritional Sciences, Adelaide BC, South Australia 5000, Australia.

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http://dx.doi.org/10.1093/mutage/geq051DOI Listing
January 2011

Induction of chromosome malsegregation by nanomaterials.

Biochem Soc Trans 2010 Dec;38(6):1691-7

Laboratory for Cell Genetics, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.

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http://dx.doi.org/10.1042/BST0381691DOI Listing
December 2010

Phenotyping for DNA repair capacity.

Mutat Res 2010 Oct 15;705(2):107-29. Epub 2010 May 15.

Laboratorium voor Cellulaire Genetica, Vrije Universiteit Brussel, Belgium.

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http://dx.doi.org/10.1016/j.mrrev.2010.05.002DOI Listing
October 2010

Special issue on in vitro MN trial.

Mutat Res 2010 Oct 21;702(2):132-4. Epub 2010 Jul 21.

School of Medicine, University of Wales-Swansea, Swansea, United Kingdom.

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http://dx.doi.org/10.1016/j.mrgentox.2010.07.004DOI Listing
October 2010

Dedication to the memory of Prof. James M. Parry.

Mutat Res 2010 Oct 2;702(2):131. Epub 2010 Aug 2.

Laboratory of Cell Genetics, Free University of Brussels, Pleinlaan 2, Brussels, Belgium.

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http://dx.doi.org/10.1016/j.mrgentox.2010.07.009DOI Listing
October 2010

Flow cytometry peripheral blood micronucleus test in vivo: determination of potential thresholds for aneuploidy induced by spindle poisons.

Environ Mol Mutagen 2010 May;51(4):278-84

Genetic Toxicology and Safety Pharmacology, Preclinical Safety, Novartis Institutes for BioMedical Research, Basel, Switzerland.

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http://dx.doi.org/10.1002/em.20542DOI Listing
May 2010

An aphidicolin-block nucleotide excision repair assay measuring DNA incision and repair capacity.

Mutagenesis 2010 Jan 20;25(1):25-32. Epub 2009 Oct 20.

Laboratory of Cell Genetics, Vrije Universiteit Brussel, Brussel, Belgium.

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http://dx.doi.org/10.1093/mutage/gep039DOI Listing
January 2010

Buccal micronucleus cytome assay.

Nat Protoc 2009 7;4(6):825-37. Epub 2009 May 7.

CSIRO Human Nutrition, Adelaide, South Australia.

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http://dx.doi.org/10.1038/nprot.2009.53DOI Listing
September 2009

Size-dependent cytotoxicity of monodisperse silica nanoparticles in human endothelial cells.

Small 2009 Apr;5(7):846-53

Laboratory of Lung Toxicology, Katholieke Universiteit Leuven, Herestraat 49, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1002/smll.200800461DOI Listing
April 2009

Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: toxicological aspects.

Chem Res Toxicol 2008 Sep 18;21(9):1698-705. Epub 2008 Jul 18.

Industrial Toxicology and Occupational Medicine Unit, Université Catholique de LouVain, Brussels, Belgium.

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http://dx.doi.org/10.1021/tx800101pDOI Listing
September 2008

Nominal and effective dosimetry of silica nanoparticles in cytotoxicity assays.

Toxicol Sci 2008 Jul 8;104(1):155-62. Epub 2008 Apr 8.

Industrial Toxicology and Occupational Medicine Unit, Université Catholique de Louvain, Avenue E. Mounier 53.02, 1200 Brussels, Belgium.

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http://dx.doi.org/10.1093/toxsci/kfn072DOI Listing
July 2008

Genomic analysis suggests higher susceptibility of children to air pollution.

Carcinogenesis 2008 May 10;29(5):977-83. Epub 2008 Mar 10.

Department of Health Risk Analysis and Toxicology, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands.

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http://dx.doi.org/10.1093/carcin/bgn065DOI Listing
May 2008

In vitro expression of hard metal dust (WC-Co)--responsive genes in human peripheral blood mononucleated cells.

Toxicol Appl Pharmacol 2008 Mar 13;227(2):299-312. Epub 2007 Nov 13.

Vrije Universiteit Brussel, Laboratorium voor Cellulaire Genetica, Pleinlaan 2, B-1050 Brussel, Belgium.

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http://linkinghub.elsevier.com/retrieve/pii/S0041008X0700499
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http://dx.doi.org/10.1016/j.taap.2007.11.002DOI Listing
March 2008

Mitotic checkpoints and the maintenance of the chromosome karyotype.

Mutat Res 2008 Mar 12;651(1-2):3-13. Epub 2007 Nov 12.

Vrije Universiteit Brussel, Laboratorium voor Cellulaire Genetica, Pleinlaan 2, 1050 Brussels, Belgium.

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http://ac.els-cdn.com/S1383571807003233/1-s2.0-S138357180700
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http://linkinghub.elsevier.com/retrieve/pii/S138357180700323
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http://dx.doi.org/10.1016/j.mrgentox.2007.10.020DOI Listing
March 2008

Survival of aneuploid, micronucleated and/or polyploid cells: crosstalk between ploidy control and apoptosis.

Mutat Res 2008 Mar 9;651(1-2):30-9. Epub 2007 Nov 9.

Vrije Universiteit Brussel, Laboratorium voor Cellulaire Genetica, Pleinlaan 2, 1050 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.mrgentox.2007.10.016DOI Listing
March 2008

Clastogenic and aneugenic effects of multi-wall carbon nanotubes in epithelial cells.

Carcinogenesis 2008 Feb 3;29(2):427-33. Epub 2008 Jan 3.

Unité de toxicologie industrielle et médecine du travail, Université catholique de Louvain, Avenue Mounier, 53.02, 1200 Bruxelles, Belgium.

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http://dx.doi.org/10.1093/carcin/bgm243DOI Listing
February 2008

hOGG1(326), XRCC1(399) and XRCC3(241) polymorphisms influence micronucleus frequencies in human lymphocytes in vivo.

Mutagenesis 2008 Jan 29;23(1):35-41. Epub 2007 Oct 29.

Laboratorium voor Cellulaire Genetica, Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussel, Belgium.

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http://dx.doi.org/10.1093/mutage/gem040DOI Listing
January 2008

Genetic susceptibility of newborn daughters to oxidative stress.

Toxicol Lett 2007 Jul 25;172(1-2):68-84. Epub 2007 May 25.

Laboratory of Cell Genetics, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.toxlet.2007.05.014DOI Listing
July 2007

Comparison of the peripheral blood micronucleus test using flow cytometry in rat and mouse exposed to aneugens after single-dose applications.

Mutagenesis 2007 Mar 6;22(2):129-34. Epub 2007 Feb 6.

Safety Profiling and Assessment, Exploratory Development, Novartis Pharma AG, MUT-2881.5.44, CH4002 Basel, Switzerland.

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http://dx.doi.org/10.1093/mutage/gel066DOI Listing
March 2007

Dose-dependent influence of genetic polymorphisms on DNA damage induced by styrene oxide, ethylene oxide and gamma-radiation.

Toxicology 2006 Feb 28;219(1-3):220-9. Epub 2005 Dec 28.

Katholieke Universiteit Leuven (K.U.L.), Laboratorium Voor Arbeidshygiëne en Toxicologie, Kapucijnenvoer 35/6, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.tox.2005.11.021DOI Listing
February 2006

Human population studies with cytogenetic biomarkers: review of the literature and future prospectives.

Environ Mol Mutagen 2005 Mar-Apr;45(2-3):258-70

Unit of Environmental Epidemiology and Biostatistics, National Cancer Research Institute, Genoa, Italy.

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http://dx.doi.org/10.1002/em.20115DOI Listing
June 2005

Influence of caspase activity on micronuclei detection: a possible role for caspase-3 in micronucleation.

Mutagenesis 2005 May 7;20(3):173-9. Epub 2005 Apr 7.

Vrije Universiteit Brussel, Laboratorium voor Cellulaire Genetica, Pleinlaan 2, B-1050 Brussel, Belgium.

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http://dx.doi.org/10.1093/mutage/gei025DOI Listing
May 2005

Influence of genetic polymorphisms on biomarkers of exposure and genotoxic effects in styrene-exposed workers.

Environ Mol Mutagen 2004 ;44(4):293-303

Katholieke Universiteit Leuven, Laboratorium voor Arbeidshygiëne en-Toxicologie, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1002/em.20069DOI Listing
December 2004

Evaluation of the apoptogenic potential of hard metal dust (WC-Co), tungsten carbide and metallic cobalt.

Toxicol Lett 2004 Dec;154(1-2):23-34

Laboratorium voor Cellulaire Genetica, Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussel, Belgium.

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http://dx.doi.org/10.1016/j.toxlet.2004.06.009DOI Listing
December 2004

Are genetic polymorphisms in OGG1, XRCC1 and XRCC3 genes predictive for the DNA strand break repair phenotype and genotoxicity in workers exposed to low dose ionising radiations?

Mutat Res 2004 Nov;556(1-2):169-81

Laboratory for Cell Genetics, Department of Biology, Free University of Brussels, Pleinlaan 2, B-1050 Brussels, Belgium.

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http://dx.doi.org/10.1016/j.mrfmmm.2004.08.002DOI Listing
November 2004

Cobalt and antimony: genotoxicity and carcinogenicity.

Mutat Res 2003 Dec;533(1-2):135-52

Laboratorium voor Cellulaire Genetica, Vrije Universiteit Brussel, Pleinlaan 2, Brussel 1050, Belgium.

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http://dx.doi.org/10.1016/j.mrfmmm.2003.07.012DOI Listing
December 2003

In vivo genotoxicity of hard metal dust: induction of micronuclei in rat type II epithelial lung cells.

Carcinogenesis 2003 Nov 29;24(11):1793-800. Epub 2003 Aug 29.

Vrije Universiteit Brussel, Laboratorium voor Cellulaire Genetica, Pleinlaan 2, 1050 Brussels, Belgium.

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http://dx.doi.org/10.1093/carcin/bgg146DOI Listing
November 2003

Indirect mechanisms of genotoxicity.

Toxicol Lett 2003 Apr;140-141:63-74

Laboratory for Cell Genetics, Vrije Universiteit Brussel, Pleinlaan 2, B-1050, Brussels, Belgium.

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http://dx.doi.org/10.1016/s0378-4274(02)00498-8DOI Listing
April 2003