Publications by authors named "Michele De Palma"

90Publications

Tweaking the DNA of myeloid cells curbs cancer spread.

Nature 2020 03;579(7798):196-197

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http://dx.doi.org/10.1038/d41586-020-00481-yDOI Listing
March 2020

Biology and therapeutic targeting of tumour-associated macrophages.

J Pathol 2020 04 14;250(5):573-592. Epub 2020 Mar 14.

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology in Lausanne (EPFL), Lausanne, Switzerland.

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http://dx.doi.org/10.1002/path.5403DOI Listing
April 2020

A LIGHTning Strike to the Metastatic Niche.

Cell Rep 2020 01;30(3):599-601

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.01.027DOI Listing
January 2020

Engineering dendritic cell vaccines to improve cancer immunotherapy.

Nat Commun 2019 11 27;10(1):5408. Epub 2019 Nov 27.

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), CH-1015, Lausanne, Switzerland.

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http://dx.doi.org/10.1038/s41467-019-13368-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881351PMC
November 2019

Lymphoma Chemotherapy: Hungry Macrophages Strike the Final Blow.

Cancer Discov 2019 Jul;9(7):834-836

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

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http://dx.doi.org/10.1158/2159-8290.CD-19-0535DOI Listing
July 2019

Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles.

Cell Rep 2019 06;27(10):3062-3080.e11

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247193061
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http://dx.doi.org/10.1016/j.celrep.2019.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581796PMC
June 2019

Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer.

Cell Rep 2019 05;27(7):1967-1978.e4

Richard Dimbleby Department of Cancer Research, Randall Division & Division of Cancer Studies, Kings College London, London, UK; Breast Cancer Now Research Unit, King's College London, Guy's Hospital, London, UK; UCL Cancer Institute, University College London, London, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247193055
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http://dx.doi.org/10.1016/j.celrep.2019.04.076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527923PMC
May 2019

Macrophage interference on chemotherapy.

Nat Cell Biol 2019 Apr;21(4):411-412

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

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http://dx.doi.org/10.1038/s41556-019-0303-8DOI Listing
April 2019

Perivascular macrophages in health and disease.

Nat Rev Immunol 2018 11;18(11):689-702

Department of Oncology & Metabolism, University of Sheffield Medical School, Sheffield, UK.

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http://dx.doi.org/10.1038/s41577-018-0056-9DOI Listing
November 2018

Consensus guidelines for the use and interpretation of angiogenesis assays.

Angiogenesis 2018 08;21(3):425-532

Angiogenesis Laboratory, Department of Medical Oncology, VU University Medical Center, Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10456-018-9613-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237663PMC
August 2018

Periostin Limits Tumor Response to VEGFA Inhibition.

Cell Rep 2018 03;22(10):2530-2540

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.02.035DOI Listing
March 2018

EVIR: chimeric receptors that enhance dendritic cell cross-dressing with tumor antigens.

Nat Methods 2018 03 22;15(3):183-186. Epub 2018 Jan 22.

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

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http://dx.doi.org/10.1038/nmeth.4579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833950PMC
March 2018

Reprogramming Tumor Blood Vessels for Enhancing Immunotherapy.

Trends Cancer 2017 12 27;3(12):809-812. Epub 2017 Oct 27.

The Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.trecan.2017.10.002DOI Listing
December 2017

Microenvironmental regulation of tumour angiogenesis.

Nat Rev Cancer 2017 08 14;17(8):457-474. Epub 2017 Jul 14.

Department of Fundamental Oncology, Ludwig Institute for Cancer Research and Division of Experimental Pathology, University of Lausanne and University of Lausanne Hospital, 1066 Lausanne, Switzerland.

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http://dx.doi.org/10.1038/nrc.2017.51DOI Listing
August 2017

CD4 T Cell Activation and Vascular Normalization: Two Sides of the Same Coin?

Immunity 2017 05;46(5):773-775

Steele Laboratories for Tumor Biology, Department of Radiation Oncology, Harvard Medical School and Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.04.015DOI Listing
May 2017

Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade.

Sci Transl Med 2017 04;9(385)

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1126/scitranslmed.aak9670DOI Listing
April 2017

Origins of Brain Tumor Macrophages.

Authors:
Michele De Palma

Cancer Cell 2016 Dec;30(6):832-833

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.11.015DOI Listing
December 2016

Perivascular Macrophages Limit Permeability.

Arterioscler Thromb Vasc Biol 2016 11 15;36(11):2203-2212. Epub 2016 Sep 15.

From the Department of Human Genetics (H.H.), Department of Molecular, Cell and Developmental Biology (J.J.M., C.M.W., R.D.F., A.I.M., S.Z., M.L.I.-A.), Molecular Biology Institute (M.L.I.-A.), and Jonsson Comprehensive Cancer Center (M.L.I.-A.), University of California, Los Angeles; Institute for Bioengineering (IBI) (E.G., M.A.S.) and The Swiss Institute for Experimental Cancer Research (ISREC) (M.L.S., C.B., M.A.S., M.D.P., M.L.I.-A.), School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Switzerland; and Institute for Molecular Engineering and Ben May Department of Cancer Research, University of Chicago, IL (W.W.K., M.A.S.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5083209PMC
http://dx.doi.org/10.1161/ATVBAHA.116.307592DOI Listing
November 2016

DICERing macrophages for reprogramming TAMs.

Cell Cycle 2016 12 5;15(23):3149-3150. Epub 2016 Aug 5.

a Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL) , 1015 Lausanne , Switzerland.

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http://dx.doi.org/10.1080/15384101.2016.1216927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5176149PMC
December 2016

Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity.

Nat Cell Biol 2016 07 13;18(7):790-802. Epub 2016 Jun 13.

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1038/ncb3371DOI Listing
July 2016

Targeting Macrophages Sensitizes Chronic Lymphocytic Leukemia to Apoptosis and Inhibits Disease Progression.

Cell Rep 2016 Feb 11;14(7):1748-1760. Epub 2016 Feb 11.

Unit of Lymphoid Malignancies, Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy; Vita-Salute San Raffaele University, 20132 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.01.042DOI Listing
February 2016

The role of the immune system in cancer: From mechanisms to clinical applications.

Authors:
Michele De Palma

Biochim Biophys Acta 2016 Jan;1865(1):1-2

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2016.01.004DOI Listing
January 2016

Cancer Metastasis: Perivascular Macrophages Under Watch.

Cancer Discov 2015 Sep;5(9):906-8

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0819DOI Listing
September 2015

Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2.

Cell Rep 2015 Feb 19;10(7):1066-81. Epub 2015 Feb 19.

Department of Cancer Biology, Metastasis Research Center, University of Texas MD Anderson Cancer Center, Houston, TX 77054, USA; Division of Matrix Biology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.01.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342328PMC
February 2015

miR-135a Inhibits Cancer Stem Cell-Driven Medulloblastoma Development by Directly Repressing Arhgef6 Expression.

Stem Cells 2015 May;33(5):1377-89

Neural Stem Cell Biology Unit, Division of Regenerative Medicine, Stem Cells and Gene Therapy, Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1002/stem.1958DOI Listing
May 2015

A niche role for periostin and macrophages in glioblastoma.

Nat Cell Biol 2015 Feb;17(2):107-9

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1038/ncb3095DOI Listing
February 2015

Assessing metastasis risk after pre-operative anti-angiogenic therapy.

EMBO Mol Med 2014 Dec;6(12):1515-7

The Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.

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http://dx.doi.org/10.15252/emmm.201404640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287970PMC
December 2014

Cancer: Metastasis risk after anti-macrophage therapy.

Nature 2014 Nov 22;515(7525):46-7. Epub 2014 Oct 22.

Swiss Institute for Experimental Cancer Research, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1038/nature13931DOI Listing
November 2014

Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells.

Cell Rep 2014 Sep 21;8(5):1432-46. Epub 2014 Aug 21.

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.07.035DOI Listing
September 2014

Role of angiopoietin-2 in adaptive tumor resistance to VEGF signaling blockade.

Cell Rep 2014 Aug 31;8(3):696-706. Epub 2014 Jul 31.

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.06.059DOI Listing
August 2014

Micromanaging restenosis by therapeutic inhibition of miR-92a.

Cardiovasc Res 2014 Sep 31;103(4):432-4. Epub 2014 Jul 31.

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne 1015, Switzerland

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http://dx.doi.org/10.1093/cvr/cvu178DOI Listing
September 2014

Micromanaging restenosis by therapeutic inhibition of miR-92a.

Cardiovasc Res 2014 Sep 31;103(4):432-4. Epub 2014 Jul 31.

Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne 1015, Switzerland

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http://dx.doi.org/10.1093/cvr/cvu178DOI Listing
September 2014

A new twist on radiation oncology: low-dose irradiation elicits immunostimulatory macrophages that unlock barriers to tumor immunotherapy.

Cancer Cell 2013 Nov;24(5):559-61

The Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL), 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.ccr.2013.10.019DOI Listing
November 2013

A role for angiopoietin-2 in organ-specific metastasis.

Cell Rep 2013 Aug;4(4):621-3

The Swiss Institute for Experimental Cancer Research ISREC, School of Life Sciences, Swiss Federal Institute of Technology Lausanne EPFL, 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.celrep.2013.07.034DOI Listing
August 2013

TIE2-expressing monocytes/macrophages regulate revascularization of the ischemic limb.

EMBO Mol Med 2013 Jun 7;5(6):858-69. Epub 2013 May 7.

Academic Department of Surgery, Cardiovascular Division, King's College London, Biomedical Research Centre at Guy's & St Thomas' NHS Foundation Trust and King's College London, UK.

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http://dx.doi.org/10.1002/emmm.201302752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779448PMC
June 2013

Reciprocal interactions between endothelial cells and macrophages in angiogenic vascular niches.

Exp Cell Res 2013 Jul 28;319(11):1626-34. Epub 2013 Mar 28.

The Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL), 1015 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2013.03.026DOI Listing
July 2013

Macrophage regulation of tumor responses to anticancer therapies.

Cancer Cell 2013 Mar;23(3):277-86

The Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL), CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.ccr.2013.02.013DOI Listing
March 2013

MicroRNA-mediated control of macrophages and its implications for cancer.

Trends Immunol 2013 Jul 13;34(7):350-9. Epub 2013 Mar 13.

The Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL), 1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.it.2013.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700601PMC
July 2013

TIE2-expressing monocytes: a novel cellular biomarker for hepatocellular carcinoma?

Hepatology 2013 Apr 6;57(4):1294-6. Epub 2013 Mar 6.

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http://dx.doi.org/10.1002/hep.26025DOI Listing
April 2013

miR-511-3p modulates genetic programs of tumor-associated macrophages.

Cell Rep 2012 Feb 9;1(2):141-54. Epub 2012 Feb 9.

Angiogenesis and Tumor Targeting Unit, and HSR-TIGET, Division of Regenerative Medicine, San Raffaele Institute, 20132-Milan, Italy.

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http://dx.doi.org/10.1016/j.celrep.2011.12.005DOI Listing
February 2012

Circulating endothelial progenitors and tumor resistance to vascular-targeting therapies.

Cancer Discov 2012 May;2(5):395-7

The Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0137DOI Listing
May 2012

Partners in crime: VEGF and IL-4 conscript tumour-promoting macrophages.

Authors:
Michele De Palma

J Pathol 2012 May 22;227(1):4-7. Epub 2012 Mar 22.

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http://dx.doi.org/10.1002/path.4008DOI Listing
May 2012

The biology of personalized cancer medicine: facing individual complexities underlying hallmark capabilities.

Mol Oncol 2012 Apr 4;6(2):111-27. Epub 2012 Feb 4.

The Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Swiss Federal Institute of Technology Lausanne (EPFL), CH-1015 Lausanne, Switzerland.

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http://dx.doi.org/10.1016/j.molonc.2012.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528366PMC
April 2012

Transplanted neural stem/precursor cells instruct phagocytes and reduce secondary tissue damage in the injured spinal cord.

Brain 2012 Feb 23;135(Pt 2):447-60. Epub 2012 Jan 23.

Dept of Clinical Neurosciences, Cambridge Centre for Brain Repair and Cambridge Stem Cell Initiative, University of Cambridge, E.D. Adrian Building, Forvie Site, Robinson Way, Cambridge CB2 0PY, UK.

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http://dx.doi.org/10.1093/brain/awr339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558737PMC
February 2012

Regulation of macrophage arginase expression and tumor growth by the Ron receptor tyrosine kinase.

J Immunol 2011 Sep 1;187(5):2181-92. Epub 2011 Aug 1.

Graduate Program in Pathobiology, Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA 16802, USA.

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http://dx.doi.org/10.4049/jimmunol.1003460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042865PMC
September 2011

The interplay between macrophages and angiogenesis in development, tissue injury and regeneration.

Int J Dev Biol 2011 ;55(4-5):495-503

San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1387/ijdb.103227snDOI Listing
November 2011

Angiopoietin-2 TIEs up macrophages in tumor angiogenesis.

Clin Cancer Res 2011 Aug 16;17(16):5226-32. Epub 2011 May 16.

Angiogenesis and Tumor Targeting Unit, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-0171DOI Listing
August 2011

Macrophage regulation of tumor angiogenesis: implications for cancer therapy.

Mol Aspects Med 2011 Apr 1;32(2):123-45. Epub 2011 May 1.

Angiogenesis and Tumor Targeting Unit, and HSR-TIGET, San Raffaele Scientific Institute, 20132 Milan, Italy.

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http://dx.doi.org/10.1016/j.mam.2011.04.005DOI Listing
April 2011

Cancer: Macrophages limit chemotherapy.

Nature 2011 Apr;472(7343):303-4

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http://dx.doi.org/10.1038/472303aDOI Listing
April 2011

Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis.

Cancer Res 2010 Oct 21;70(19):7500-13. Epub 2010 Sep 21.

Neural Stem Cell Biology Unit, Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-2353DOI Listing
October 2010

A double agent in cancer: deciphering macrophage roles in human tumors.

Nat Med 2010 Aug;16(8):861-2

UCL Institute of Ophthalmology, University College London, London, UK.

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http://dx.doi.org/10.1038/nm0810-861DOI Listing
August 2010

Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions.

Cancer Res 2010 Jul 8;70(13):5270-80. Epub 2010 Jun 8.

Academic Unit of Inflammation and Tumour Targeting, University of Sheffield Medical School, Sheffield, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-0012DOI Listing
July 2010

Antagonizing metastasis.

Nat Biotechnol 2010 Apr;28(4):331-2

San Raffaele Telethon Institute for Gene Therapy and Vita Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1038/nbt0410-331DOI Listing
April 2010

Elusive identities and overlapping phenotypes of proangiogenic myeloid cells in tumors.

Am J Pathol 2010 Apr 18;176(4):1564-76. Epub 2010 Feb 18.

Medical School, University of Sheffield, Sheffield, S10 2RX, UK.

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http://dx.doi.org/10.2353/ajpath.2010.090786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843445PMC
April 2010

Tie2-expressing monocytes (TEMs): novel targets and vehicles of anticancer therapy?

Biochim Biophys Acta 2009 Aug 10;1796(1):5-10. Epub 2009 Apr 10.

Angiogenesis and Tumor Targeting Research Unit, San Raffaele Scientific Institute, via Olgettina, 58, 20132 Milan, Italy; San Raffaele-Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, via Olgettina, 58, 20132 Milan, Italy.

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http://dx.doi.org/10.1016/j.bbcan.2009.04.001DOI Listing
August 2009

Pancreatic-type acinar cell carcinoma of the stomach beneath a focus of pancreatic metaplasia of the gastric mucosa.

Hum Pathol 2009 May 13;40(5):746-9. Epub 2009 Jan 13.

Section of Anatomic Pathology, Department of Oncology and Hematology, University of Bologna, Bellaria Hospital, 40139 Bologna, Italy.

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http://dx.doi.org/10.1016/j.humpath.2008.10.006DOI Listing
May 2009

Tie2-expressing monocytes: regulation of tumor angiogenesis and therapeutic implications.

Trends Immunol 2007 Dec 5;28(12):519-24. Epub 2007 Nov 5.

Angiogenesis and Tumor Targeting Research Unit and San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, Via Olgettina, Milan, Italy.

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http://dx.doi.org/10.1016/j.it.2007.09.004DOI Listing
December 2007

Tie2-expressing monocytes and tumor angiogenesis: regulation by hypoxia and angiopoietin-2.

Cancer Res 2007 Sep;67(18):8429-32

Tumor Targeting Group, Academic Unit of Pathology, The Sir Henry Wellcome Laboratories for Medical Research, University of Sheffield Medical School, Sheffield, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-1684DOI Listing
September 2007

Role of haematopoietic cells and endothelial progenitors in tumour angiogenesis.

Biochim Biophys Acta 2006 Aug 27;1766(1):159-66. Epub 2006 Jun 27.

Angiogenesis and Tumour Targeting Research Unit, San Raffaele Scientific Institute, via Olgettina, 58, 20132 Milan, Italy.

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http://dx.doi.org/10.1016/j.bbcan.2006.06.003DOI Listing
August 2006

Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells.

Blood 2005 Mar 12;105(6):2307-15. Epub 2004 Nov 12.

San Raffaele-Telethon Institute for Gene Therapy (HSR-TIGET), via Olgettina 58, 20132, Milan, Italy.

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http://dx.doi.org/10.1182/blood-2004-03-0798DOI Listing
March 2005

In vivo targeting of tumor endothelial cells by systemic delivery of lentiviral vectors.

Hum Gene Ther 2003 Aug;14(12):1193-206

Laboratory for Gene Transfer and Therapy, IRCC, Institute for Cancer Research and Treatment, University of Turin Medical School, 10060 Candiolo (Turin), Italy.

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http://dx.doi.org/10.1089/104303403322168028DOI Listing
August 2003

Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells.

Nat Med 2003 Jun 12;9(6):789-95. Epub 2003 May 12.

Laboratory for Gene Transfer and Therapy, IRCC, Institute for Cancer Research and Treatment, University of Torino Medical School, Strada Provinciale 142, 10060 Candiolo, Torino, Italy.

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http://dx.doi.org/10.1038/nm871DOI Listing
June 2003

Transduction of a gene expression cassette using advanced generation lentiviral vectors.

Methods Enzymol 2002 ;346:514-29

Institute for Cancer Research and Treatment, Laboratory for Gene Transfer and Therapy, University of Torino Medical School, 10060 Candiolo, Torino, Italy.

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http://dx.doi.org/10.1016/s0076-6879(02)46074-0DOI Listing
April 2002