Publications by authors named "Michele Cea"

71Publications

The Novel Phosphatidylinositol-3-Kinase (PI3K) Inhibitor Alpelisib Effectively Inhibits Growth of PTEN-Haploinsufficient Lipoma Cells.

Cancers (Basel) 2019 Oct 17;11(10). Epub 2019 Oct 17.

Pediatric Research Center, University Hospital for Children and Adolescents, Leipzig University, 04103 Leipzig, Germany.

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October 2019

Nutrients in the Prevention of Alzheimer's Disease.

Oxid Med Cell Longev 2019 4;2019:9874159. Epub 2019 Sep 4.

Department of Internal Medicine and Medical Specialties, Section of Geriatrics, IRCCS Ospedale Policlinico San Martino, Genova, Italy.

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March 2020

SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells.

FASEB J 2019 03 4;33(3):3704-3717. Epub 2018 Dec 4.

Section of Biochemistry, Department of Experimental Medicine, Center for Excellence in Biomedical Research (CEBR), University of Genoa, Genoa, Italy.

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March 2019

SIRT6 inhibitors with salicylate-like structure show immunosuppressive and chemosensitizing effects.

Bioorg Med Chem 2017 10 19;25(20):5849-5858. Epub 2017 Sep 19.

Department of Experimental Medicine, Section of Biochemistry, University of Genoa, V.le Benedetto XV 1, 16132 Genoa, Italy; CEBR, University of Genova, V.le Benedetto XV, 7, 16132 Genoa, Italy. Electronic address:

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October 2017

Do Cancer Drugs Counteract Neurodegeneration? Repurposing for Alzheimer's Disease.

J Alzheimers Dis 2017 ;55(4):1295-1306

Section of Geriatrics, Department of Internal Medicine and Medical Specialties (DIMI), University of Genoa, Genoa, Italy.

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February 2018

Targeting Inflammation in Primary Cardiovascular Prevention.

Curr Pharm Des 2016 ;22(37):5662-5675

First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, 6 viale Benedetto XV, 16132 Genoa, Italy.

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December 2017

Exploiting tumor vulnerabilities: NAD(+)-depleting agents combined with anti-tumor drugs as innovative strategy to treat hematological malignancies.

Expert Rev Anticancer Ther 2016 09 22;16(9):897-8. Epub 2016 Jul 22.

a Chair of Hematology, Department of Medicine (DiMI) , University of Genoa, AOU, I.R.C.C.S. San Martino -IST , Genova , Italy.

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September 2016

Evaluation of prognostic indices in elderly hospitalized patients.

Geriatr Gerontol Int 2017 Jun 15;17(6):1015-1021. Epub 2016 Jun 15.

Section of Geriatrics, Department of Internal Medicine and Medical Specialties (DIMI), University of Genoa, Genoa, Italy.

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June 2017

APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment.

Blood 2016 06 28;127(25):3225-36. Epub 2016 Apr 28.

The Jerome Lipper Multiple Myeloma Center, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA; Department of Medicine, Harvard Medical School, Boston, MA;

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June 2016

Biological Insights into Myeloma and Other B Cell Malignancies.

Biomed Res Int 2016 16;2016:5218093. Epub 2016 Feb 16.

Washington University, Saint Louis, MO 63108, USA.

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December 2016

Mechanisms and Clinical Applications of Genome Instability in Multiple Myeloma.

Biomed Res Int 2015 22;2015:943096. Epub 2015 Oct 22.

Hematology Unit, Department of Internal Medicine (DiMI), University of Genoa, IRCCS AOU San Martino-IST, 1600 Genoa, Italy.

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August 2016

Role of genotype-based approach in the clinical management of adult acute myeloid leukemia with normal cytogenetics.

Leuk Res 2014 Jun 18;38(6):649-59. Epub 2014 Mar 18.

Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Department of Hematology and Oncology, I.R.C.C.S. A.O.U. San Martino-IST, Genoa, Italy. Electronic address:

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June 2014

Chronic myeloid leukemia: reaching for the cure.

Curr Cancer Drug Targets 2013 Sep;13(7):709-10

Department of Internal Medicine University of Genoa V.le Benedetto XV 6, 16132 Genoa Italy.

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September 2013

New insights into biology of chronic myeloid leukemia: implications in therapy.

Curr Cancer Drug Targets 2013 Sep;13(7):711-23

Department of Medical Oncology, Dana-Farber Cancer Institute, M551, 450 Brookline Avenue, Boston, MA 02115, USA.

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September 2013

Intracellular NAD⁺ depletion enhances bortezomib-induced anti-myeloma activity.

Blood 2013 Aug 3;122(7):1243-55. Epub 2013 Jul 3.

LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

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August 2013

Intracellular NAD(+) depletion induces autophagic death in multiple myeloma cells.

Autophagy 2013 Mar;9(3):410-2

LeBow Institute for Myeloma Therapeutics and Jerome Lipper Center for Multiple Myeloma Research, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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March 2013

New insights into the treatment of multiple myeloma with histone deacetylase inhibitors.

Curr Pharm Des 2013 ;19(4):734-44

Department of Medical Oncology, Dana-Farber Cancer Institute, M551, 450 Brookline Avenue, Boston, MA 02115, USA.

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July 2013

Synthesis of new oxathiazinane dioxides and their in vitro cancer cell growth inhibitory activity.

Bioorg Med Chem Lett 2010 Sep 10;20(17):5353-6. Epub 2009 Sep 10.

Laboratory of Glycochemistry and Asymmetric Synthesis, Swiss Institute of Technology (EPFL), Lausanne, Switzerland.

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September 2010

Monoclonal antibodies for non-Hodgkin's lymphoma: state of the art and perspectives.

Clin Dev Immunol 2010 6;2010:428253. Epub 2011 Mar 6.

Department of Internal Medicine, University of Genoa, Room 221, V.le Benedetto XV 6, 16132 Genoa, Italy.

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July 2011

Calciphylaxis in a patient with POEMS syndrome without renal failure and/or hyperparathyroidism. A case report.

Ann Ital Med Int 2004 Oct-Dec;19(4):283-7

Dipartimento di Scienze Biomediche e Oncologia Umana, Università degli Studi di Bari.

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March 2005