Publications by authors named "Michele Caraglia"

100Publications

Toll-like receptors and COVID-19: a two-faced story with an exciting ending.

Future Sci OA 2020 Jul 30;6(8):FSO605. Epub 2020 Jul 30.

Regional Reference Center for Rare Tumors, Department of Oncology & Hematology, AOU Federico II of Naples, Naples, Italy.

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http://dx.doi.org/10.2144/fsoa-2020-0091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7434222PMC
July 2020

miRNA profile is altered in a modified EAE mouse model of multiple sclerosis featuring cortical lesions.

Elife 2020 09 17;9. Epub 2020 Sep 17.

Bioanalysis and Pharmacology of Bioactive Lipids Research Group, Louvain Drug Research Institute, UCLouvain, Université catholique de Louvain, Bruxelles, Belgium.

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http://dx.doi.org/10.7554/eLife.56916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498263PMC
September 2020

Extracellular Vesicles: New Endogenous Shuttles for miRNAs in Cancer Diagnosis and Therapy?

Int J Mol Sci 2020 Sep 4;21(18). Epub 2020 Sep 4.

Department of Precision Medicine, University of Campania "L. Vanvitelli", 80138 Naples, Italy.

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http://dx.doi.org/10.3390/ijms21186486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555972PMC
September 2020

Hybrid lipid self-assembling nanoparticles for brain delivery of microRNA.

Int J Pharm 2020 Oct 2;588:119693. Epub 2020 Aug 2.

Department of Pharmacy, University Federico II of Naples, Via Domenico Montesano, 49, 80131 Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2020.119693DOI Listing
October 2020

MGMT Promoter Methylation as a Target In Metastatic Colorectal Cancer: Rapid Turnover and Use of Folates Alter its Study-Letter.

Clin Cancer Res 2020 Jul;26(13):3493-3494

Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy; Biogem Scarl, Institute of Genetic Research, Laboratory of Precision and Molecular Oncology, Ariano Irpino, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-3991DOI Listing
July 2020

Definition of miRNA Signatures of Nodal Metastasis in LCa: miR-449a Targets Notch Genes and Suppresses Cell Migration and Invasion.

Mol Ther Nucleic Acids 2020 Jun 21;20:711-724. Epub 2020 Apr 21.

Department of Precision Medicine, University of Campania "Luigi Vanvitelli," Naples, Italy; IRGS, Biogem, Molecular Oncology and Precision Medicine Laboratory, Via Camporeale, 83031 Ariano Irpino, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2020.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218231PMC
June 2020

Anti-Inflammatory Drugs as Anticancer Agents.

Int J Mol Sci 2020 Apr 9;21(7). Epub 2020 Apr 9.

Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.

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http://dx.doi.org/10.3390/ijms21072605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7177823PMC
April 2020

From single gene analysis to single cell profiling: a new era for precision medicine.

J Exp Clin Cancer Res 2020 Mar 5;39(1):48. Epub 2020 Mar 5.

Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples and Biogem Scarl, Institute of Genetic Research, Laboratory of Precision and Molecular Oncology, Ariano Irpino, Italy.

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http://dx.doi.org/10.1186/s13046-020-01549-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059661PMC
March 2020

Could PD-1/PDL1 immune checkpoints be linked to HLA signature?

Immunotherapy 2019 12 9;11(18):1523-1526. Epub 2019 Dec 9.

Medical Oncology Unit, AUO "MaterDomini" & "Magna Graecia" University, Catanzaro, Italy.

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http://dx.doi.org/10.2217/imt-2019-0160DOI Listing
December 2019

Salivary mir-27b Expression in Oral Lichen Planus Patients: A Series of Cases and a Narrative Review of Literature.

Curr Top Med Chem 2019 ;19(31):2816-2823

Department of Biochemistry, Biophysics and General Pathology, University of Campania "L. Vanvitelli", Via S.M. Costantinopoli 16, 80138 Naples, Italy.

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http://dx.doi.org/10.2174/1568026619666191121144407DOI Listing
February 2020

Correction to: Cell communication and signaling: how to turn bad language into positive one.

J Exp Clin Cancer Res 2019 Oct 25;38(1):425. Epub 2019 Oct 25.

Experimental Oncology Lab, CRS Development of Biomolecular Therapies, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

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http://dx.doi.org/10.1186/s13046-019-1431-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814022PMC
October 2019

A Hydroquinone-Based Derivative Elicits Apoptosis and Autophagy via Activating a ROS-Dependent Unfolded Protein Response in Human Glioblastoma.

Int J Mol Sci 2019 Aug 6;20(15). Epub 2019 Aug 6.

Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", via L. De Crecchio 7, 80138 Naples, Italy.

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http://dx.doi.org/10.3390/ijms20153836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696486PMC
August 2019

Urotensin II receptor expression in patients with ulcerative colitis: a pilot study.

Minerva Gastroenterol Dietol 2020 Mar 9;66(1):23-28. Epub 2019 Jul 9.

Department of Precision Medicine, Luigi Vanvitelli University of Campania, Naples, Italy.

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http://dx.doi.org/10.23736/S1121-421X.19.02602-3DOI Listing
March 2020

Mitochondria as playmakers of apoptosis, autophagy and senescence.

Semin Cell Dev Biol 2020 02 27;98:139-153. Epub 2019 Jun 27.

Department of Precision Medicine, University of Campania "Luigi Vanvitelli", 80138, Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2019.05.022DOI Listing
February 2020

PYK2 promotes HER2-positive breast cancer invasion.

J Exp Clin Cancer Res 2019 May 22;38(1):210. Epub 2019 May 22.

The John van Geest Cancer Research Centre, School of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham, NG11 8NS, UK.

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http://dx.doi.org/10.1186/s13046-019-1221-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532260PMC
May 2019

Cell communication and signaling: how to turn bad language into positive one.

J Exp Clin Cancer Res 2019 Mar 13;38(1):128. Epub 2019 Mar 13.

Experimental Oncology Lab, CRS Development of Biomolecular Therapies, Orthopaedic Rizzoli Institute, Bologna, Italy.

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https://jeccr.biomedcentral.com/articles/10.1186/s13046-019-
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http://dx.doi.org/10.1186/s13046-019-1122-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417210PMC
March 2019

Targeting Autophagy to Overcome Human Diseases.

Int J Mol Sci 2019 Feb 8;20(3). Epub 2019 Feb 8.

National Center for Drug Research and Evaluation, National Institute of Health, Viale Regina Elena, 00161 Rome, Italy.

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http://dx.doi.org/10.3390/ijms20030725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387456PMC
February 2019

CheckMate 141 trial: all that glitters is not gold.

Expert Opin Biol Ther 2019 03 21;19(3):169-171. Epub 2019 Jan 21.

e Department of Precision Medicine , University of Campania "L. Vanvitelli" , Naples and Biogem , Avellino Italy.

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http://dx.doi.org/10.1080/14712598.2019.1570498DOI Listing
March 2019

Oral and Oropharyngeal squamous cell carcinoma: prognostic and predictive parameters in the etiopathogenetic route.

Expert Rev Anticancer Ther 2019 02 15;19(2):105-119. Epub 2019 Jan 15.

a Pathology Unit, Mental and Physical Health and Preventive Medicine Department , Università degli Studi della Campania 'Luigi Vanvitelli' , Naples , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14737140.2019.1
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http://dx.doi.org/10.1080/14737140.2019.1561288DOI Listing
February 2019

AdoMet triggers apoptosis in head and neck squamous cancer by inducing ER stress and potentiates cell sensitivity to cisplatin.

J Cell Physiol 2019 08 21;234(8):13277-13291. Epub 2018 Dec 21.

Department of Precision Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1002/jcp.28000DOI Listing
August 2019

Chitosan-coated liposomes loaded with butyric acid demonstrate anticancer and anti-inflammatory activity in human hepatoma HepG2 cells.

Oncol Rep 2019 Mar 13;41(3):1476-1486. Epub 2018 Dec 13.

Internal Medicine and Hepatology Division, Department of Medicine, University of Medicine of Salerno, Salerno, I-80123 Naples, Italy.

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http://dx.doi.org/10.3892/or.2018.6932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365699PMC
March 2019

Oxidative stress in chronic lymphocytic leukemia: still a matter of debate.

Leuk Lymphoma 2019 04 20;60(4):867-875. Epub 2018 Sep 20.

d Laboratory of Preclinical and Translational Research , IRCCS-CROB, Referral Cancer Center of Basilicata , Rionero in Vulture , Italy.

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http://dx.doi.org/10.1080/10428194.2018.1509317DOI Listing
April 2019

Aryl hydrocarbon receptor, a tumor grade‑associated marker of oral cancer, is directly downregulated by polydatin: A pilot study.

Oncol Rep 2018 Sep 10;40(3):1435-1442. Epub 2018 Jul 10.

Department of Clinical and Experimental Medicine, University of Foggia, I-71122 Foggia, Italy.

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http://dx.doi.org/10.3892/or.2018.6555DOI Listing
September 2018

Anti-Cancer and Radio-Sensitizing Effects of Curcumin in Nasopharyngeal Carcinoma.

Curr Pharm Des 2018 ;24(19):2121-2128

Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad 9177948564, Iran.

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http://dx.doi.org/10.2174/1381612824666180522105202DOI Listing
October 2019

Autophagy induction by trehalose: Molecular mechanisms and therapeutic impacts.

J Cell Physiol 2018 09 16;233(9):6524-6543. Epub 2018 Apr 16.

Neurogenic inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

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http://dx.doi.org/10.1002/jcp.26583DOI Listing
September 2018

Structural Characterization of Self-Assembling Hybrid Nanoparticles for Bisphosphonate Delivery in Tumors.

Mol Pharm 2018 03 20;15(3):1258-1265. Epub 2018 Feb 20.

Department of Pharmacy , University of Naples Federico II , Via Domenico Montesano 49 , 80131 Naples , Italy.

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http://dx.doi.org/10.1021/acs.molpharmaceut.7b01085DOI Listing
March 2018

Regulatory T Cells and Their Prognostic Relevance in Hematologic Malignancies.

J Immunol Res 2017 21;2017:1832968. Epub 2017 Dec 21.

Centre of Excellence for Biomedical Research, Department of Internal Medicine, IRCCS Azienda Ospedaliero Universitaria San Martino-IST-Istituto Nazionale per la Ricerca sul Cancro, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1155/2017/1832968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752970PMC
August 2018

Ipilimumab for the treatment of metastatic prostate cancer.

Expert Opin Biol Ther 2018 02 28;18(2):205-213. Epub 2017 Dec 28.

a Department of Biochemistry, Biophysics and General Pathology , University of Campania "L. Vanvitelli" , Naples , Italy.

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http://dx.doi.org/10.1080/14712598.2018.1420777DOI Listing
February 2018

Testicular cancer from diagnosis to epigenetic factors.

Oncotarget 2017 Nov 18;8(61):104654-104663. Epub 2017 Sep 18.

Progetto ONCONET 2.0, Linea progettuale 14 per l'implementazione della prevenzione e diagnosi precoce del tumore alla prostata e testicolo, Regione Campania, Italy.

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http://dx.doi.org/10.18632/oncotarget.20992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732834PMC
November 2017

Dickkopf homolog 3 (DKK3): A candidate for detection and treatment of cancers?

J Cell Physiol 2018 06 15;233(6):4595-4605. Epub 2018 Jan 15.

Biotechnology Research Center, Mashhad University of Medical Sciences, Pharmaceutical Technology Institute, Mashhad, Iran.

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http://dx.doi.org/10.1002/jcp.26313DOI Listing
June 2018

Determination of miRNAs from Cancer Stem Cells Using a Low Density Array Platform.

Methods Mol Biol 2018 ;1692:149-156

Department of Biochemistry, Biophysics and General Pathology, University of Campania "Luigi Vanvitelli", Via L. De Crecchio 7, Naples, 80138, Italy.

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http://dx.doi.org/10.1007/978-1-4939-7401-6_14DOI Listing
June 2018

UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism.

Free Radic Biol Med 2017 12 27;113:176-189. Epub 2017 Sep 27.

Department of Neuroscience, Biomedicine and Movement, Biochemistry Section, University of Verona, Verona, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2017.09.022DOI Listing
December 2017

Vascular endothelial growth factor: An important molecular target of curcumin.

Crit Rev Food Sci Nutr 2019 25;59(2):299-312. Epub 2017 Sep 25.

e Biotechnology Research Center , Mashhad University of Medical Sciences , Mashhad , Iran.

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http://dx.doi.org/10.1080/10408398.2017.1366892DOI Listing
July 2019

FOLFOXIRI in metastatic colorectal cancer: A criticism from its native land.

Cancer Lett 2017 11 24;408:71-72. Epub 2017 Aug 24.

Department of Abdominal Oncology, National Cancer Institute of Naples, Istituto Nazionale Tumori di Napoli, IRCCS "G. Pascale", Via Mariano Semmola, 80131, Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.08.025DOI Listing
November 2017

Non-coding RNAs as a new dawn in tumor diagnosis.

Semin Cell Dev Biol 2018 06 29;78:37-50. Epub 2017 Jul 29.

Department of Biochemistry, Biophysics and General Pathology, University of Campania "Luigi Vanvitelli", Via L. De Crecchio 7, 80138 Naples, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2017.07.035DOI Listing
June 2018

S-Adenosylmethionine-mediated apoptosis is potentiated by autophagy inhibition induced by chloroquine in human breast cancer cells.

J Cell Physiol 2018 Feb 22;233(2):1370-1383. Epub 2017 Jun 22.

Department of Biochemistry, Biophysics and General Pathology, University of Campania "Luigi Vanvitelli," Naples, Italy.

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http://dx.doi.org/10.1002/jcp.26015DOI Listing
February 2018

The novel role of pyrvinium in cancer therapy.

J Cell Physiol 2018 04 20;233(4):2871-2881. Epub 2017 Jun 20.

Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

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http://doi.wiley.com/10.1002/jcp.26006
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http://dx.doi.org/10.1002/jcp.26006DOI Listing
April 2018

Fasting inhibits hepatic stellate cells activation and potentiates anti-cancer activity of Sorafenib in hepatocellular cancer cells.

J Cell Physiol 2018 Feb 11;233(2):1202-1212. Epub 2017 Jul 11.

Center for Translational Medicine (CTM), International Clinical Research Center (ICRC), St. Anne's University Hospital, Brno, Czech Republic.

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http://dx.doi.org/10.1002/jcp.25987DOI Listing
February 2018

Hepatocarcinoma: genetic and epigenetic features.

Minerva Gastroenterol Dietol 2018 Mar 11;64(1):14-27. Epub 2017 Apr 11.

Department of Biochemistry, Biophysics and General Pathology, University of Campania "L. Vanvitelli", Naples, Italy -

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http://dx.doi.org/10.23736/S1121-421X.17.02408-4DOI Listing
March 2018

Naturally occurring anti-cancer agents targeting EZH2.

Cancer Lett 2017 08 18;400:325-335. Epub 2017 Mar 18.

Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad 9177948564, Iran. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.03.020DOI Listing
August 2017

Measurement of Autophagy by Flow Cytometry.

Methods Mol Biol 2017 ;1553:209-216

Department of Biochemistry, Biophysics and General Pathology, Second University of Naples, Via L. De Crecchio, 7, Naples, 80138, Italy.

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http://dx.doi.org/10.1007/978-1-4939-6756-8_16DOI Listing
February 2018

The Role of Target Therapy in the Treatment of Gastrointestinal Noncolorectal Cancers: Clinical Impact and Cost Consideration.

Curr Cancer Drug Targets 2018 ;18(5):430-441

Medical Oncology, Abdominal Department, National Cancer Institute G. Pascale Foundation, Napoli, Italy.

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http://dx.doi.org/10.2174/1568009617666170208162058DOI Listing
August 2019

Immunotherapy of colorectal cancer: new perspectives after a long path.

Immunotherapy 2016 11;8(11):1281-1292

Medical Oncology Unit & Medical Oncology Unit, AUO 'Materdomini', Magna Grecia University, Catanzaro, Italy.

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http://dx.doi.org/10.2217/imt-2016-0089DOI Listing
November 2016

MicroRNA-125a-5p Is a Downstream Effector of Sorafenib in Its Antiproliferative Activity Toward Human Hepatocellular Carcinoma Cells.

J Cell Physiol 2017 Jul 16;232(7):1907-1913. Epub 2017 Feb 16.

Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania "L. Vanvitelli", Caserta, Italy.

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http://doi.wiley.com/10.1002/jcp.25744
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http://dx.doi.org/10.1002/jcp.25744DOI Listing
July 2017

Impact of curcumin on the regulation of microRNAs in colorectal cancer.

Expert Rev Gastroenterol Hepatol 2017 Feb 9;11(2):99-101. Epub 2016 Dec 9.

d Neurogenic Inflammation Research Center , Mashhad University of Medical Sciences , Mashhad , Iran.

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http://dx.doi.org/10.1080/17474124.2017.1268528DOI Listing
February 2017

Tissue transglutaminase (TG2) is involved in the resistance of cancer cells to the histone deacetylase (HDAC) inhibitor vorinostat.

Amino Acids 2017 03 19;49(3):517-528. Epub 2016 Oct 19.

Experimental Pharmacology Unit, Istituto Nazionale Tumori Fondazione G. Pascale-IRCCS, 80131, Naples, Italy.

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http://dx.doi.org/10.1007/s00726-016-2338-5DOI Listing
March 2017

The strange connection between epidermal growth factor receptor tyrosine kinase inhibitors and dapsone: from rash mitigation to the increase in anti-tumor activity.

Curr Med Res Opin 2016 11 11;32(11):1839-1848. Epub 2016 Aug 11.

a Department of Biochemistry, Biophysics and General Pathology , Second University of Naples , Naples , Italy.

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http://dx.doi.org/10.1080/03007995.2016.1211522DOI Listing
November 2016

Pembrolizumab: the value of PDL1 biomarker in head and neck cancer.

Expert Opin Biol Ther 2016 09 21;16(9):1075-8. Epub 2016 Jul 21.

c Merck Sharp Dohme , Department of Oncology , Milan , Italy.

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http://dx.doi.org/10.1080/14712598.2016.1211635DOI Listing
September 2016

Erratum to: The methyl donor S-adenosylmethionine potentiates doxorubicin effects on apoptosis of hormone-dependent breast cancer cell lines.

Endocrine 2016 09;53(3):875

Department of Biochemistry, Biophysics and General Pathology, Second University of Naples, Via L. De Crecchio 7, Naples, 80138, Italy.

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http://dx.doi.org/10.1007/s12020-016-1001-yDOI Listing
September 2016

Erratum to: PI3K/Akt/mTOR signaling in medullary thyroid cancer: a promising molecular target for cancer therapy.

Endocrine 2016 09;53(3):874

Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1007/s12020-016-1000-zDOI Listing
September 2016