Michele Brignole

Michele Brignole

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Michele Brignole

Publications by authors named "Michele Brignole"

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Reproducibility of carotid sinus massage.

Pacing Clin Electrophysiol 2020 May 4. Epub 2020 May 4.

Dept of Cardiology, , Arrhythmology Centre and Syncope Unit, Ospedali del Tigullio, Lavagna, Italy.

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http://dx.doi.org/10.1111/pace.13934DOI Listing
May 2020

Adenosine and the Cardiovascular System: The Good and the Bad.

J Clin Med 2020 May 6;9(5). Epub 2020 May 6.

Department of Medicine and Surgery, University of Milano Bicocca, 20122 Milan, Italy.

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http://dx.doi.org/10.3390/jcm9051366DOI Listing
May 2020

Additional benefits of nonconventional modalities of cardiac resynchronization therapy using His bundle pacing.

J Cardiovasc Electrophysiol 2020 Mar 24;31(3):647-657. Epub 2020 Jan 24.

Department of Cardiology, Arrhythmia Centre, Ospedali del Tigullio, Lavagna, Genoa, Italy.

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http://dx.doi.org/10.1111/jce.14359DOI Listing
March 2020

Syncope in the Young Adult and in the Athlete: Causes and Clinical Work-up to Exclude a Life-Threatening Cardiac Disease.

J Cardiovasc Transl Res 2020 Mar 20. Epub 2020 Mar 20.

Faint&Fall Programme, IRCCS Istituto Auxologico Italiano, Milan, Italy.

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http://dx.doi.org/10.1007/s12265-020-09989-0DOI Listing
March 2020

Neuro-arrhythmology: a challenging field of action and research: a review from the Task Force of Neuro-arrhythmology of Italian Association of Arrhythmias and Cardiac Pacing.

J Cardiovasc Med (Hagerstown) 2019 Nov;20(11):731-744

Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena University Hospital, Modena, Italy.

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http://dx.doi.org/10.2459/JCM.0000000000000866DOI Listing
November 2019

ACC/AHA/HRS Versus ESC Guidelines for the Diagnosis and Management of Syncope: JACC Guideline Comparison.

J Am Coll Cardiol 2019 11;74(19):2410-2423

Department of Medicine, Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

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http://dx.doi.org/10.1016/j.jacc.2019.09.012DOI Listing
November 2019

Loss of His bundle capture due to repetitive non-re-entrant "ventriculohisian" synchrony.

J Cardiovasc Electrophysiol 2019 Sep 18;30(9):1710-1713. Epub 2019 Jun 18.

Department of Cardiology, Arrhythmology Centre, Ospedali del Tigullio, Lavagna, Italy.

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http://dx.doi.org/10.1111/jce.14011DOI Listing
September 2019

Efficacy of theophylline in patients with syncope without prodromes with normal heart and normal ECG.

Int J Cardiol 2019 08 22;289:70-73. Epub 2019 Mar 22.

Department of Cardiology, Hopital La Timone Adultes, Marseille, France; UMR MD2, Aix Marseille University, Institute of Biological research of the French Army (IRBA), Marseille, France.

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http://dx.doi.org/10.1016/j.ijcard.2019.03.043DOI Listing
August 2019

Reply to the letter of Satish R. Ray et al. of 28 August 2018.

Eur Heart J 2019 01;40(1):71

Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Leiden, the Netherlands.

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http://dx.doi.org/10.1093/eurheartj/ehy787DOI Listing
January 2019

[What's new in the 2018 ESC guidelines for the diagnosis and management of syncope?]

G Ital Cardiol (Rome) 2018 Dec;19(12):668-671

Dipartimento di Cardiologia, Centro Aritmologico, Ospedali del Tigullio, Lavagna (GE).

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http://dx.doi.org/10.1714/3027.30249DOI Listing
December 2018

Outreach syncope clinic managed by a nurse practitioner: Outcome and cost effectiveness.

J Telemed Telecare 2018 Sep 25;24(8):566-571. Epub 2017 Jul 25.

1 Division of Cardiovascular Medicine, University of Wisconsin, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1177/1357633X17718087DOI Listing
September 2018

Incidence and predictors of syncope recurrence after cardiac pacing in patients with carotid sinus syndrome.

Int J Cardiol 2018 Sep;266:119-123

Syncope Unit, Geriatric Intensive Care Medicine, University of Florence and Azienda Ospedaliero Universitaria Careggi, Florence, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2018.03.144DOI Listing
September 2018

The benefit of pacemaker therapy in patients with neurally mediated syncope and documented asystole: a meta-analysis of implantable loop recorder studies.

Europace 2018 08;20(8):1362-1366

Department of Cardiology, University of Florence, AOU Careggi, Viale Pieraccini 6, Florence, Italy.

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http://dx.doi.org/10.1093/europace/eux321DOI Listing
August 2018

Emerging concepts in diagnosis and treatment of syncope by pacing.

Trends Cardiovasc Med 2018 08 13;28(6):421-426. Epub 2018 Feb 13.

Division of Cardiology, University of Wisconsin, Madison, WI.

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http://dx.doi.org/10.1016/j.tcm.2018.01.009DOI Listing
August 2018

The pathophysiology of the vasovagal response.

Heart Rhythm 2018 06 12;15(6):921-929. Epub 2017 Dec 12.

Departments of Pediatrics, Physiology, and Medicine, New York Medical College, Valhalla, New York.

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http://dx.doi.org/10.1016/j.hrthm.2017.12.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984661PMC
June 2018

[Do we need syncope units? : Experience from Bolzano, South Tyrol (Italy)].

Herzschrittmacherther Elektrophysiol 2018 Jun 14;29(2):199-203. Epub 2018 May 14.

Department of Cardiology, Ospedali Tigullio, 16033, Lavagna, Italien.

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http://dx.doi.org/10.1007/s00399-018-0561-3DOI Listing
June 2018

Adenosine hypersensitivity and atrioventricular block.

Herzschrittmacherther Elektrophysiol 2018 Jun 29;29(2):166-170. Epub 2018 May 29.

Service de Cardiologie, CHU La Timone, 13005, Marseille, France.

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http://dx.doi.org/10.1007/s00399-018-0570-2DOI Listing
June 2018

Theophylline as an adjunct to control malignant ventricular arrhythmia associated with early repolarization.

Pacing Clin Electrophysiol 2018 05 7;41(5):444-446. Epub 2017 Dec 7.

Service de Cardiologie-Rythmologie, CHU la Timone, Marseille, France.

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http://doi.wiley.com/10.1111/pace.13240
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http://dx.doi.org/10.1111/pace.13240DOI Listing
May 2018

Psychogenic pseudosyncope: Not always a diagnosis of exclusion.

Pacing Clin Electrophysiol 2018 05 31;41(5):480-486. Epub 2018 Mar 31.

Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

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http://dx.doi.org/10.1111/pace.13316DOI Listing
May 2018

Migration of an 'injectable' loop recorder in the dorsal pleural cavity.

Europace 2018 01;20(1):24

Departments of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, via don Bosco 24, 16033, Lavagna, Italy.

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http://dx.doi.org/10.1093/europace/eux222DOI Listing
January 2018

Syncope and paroxysmal atrioventricular block.

J Arrhythm 2017 Dec 8;33(6):562-567. Epub 2017 May 8.

Arrhythmology Center, Department of Cardiology, Ospedali del Tigullio, 16033 Lavagna, Italy.

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http://dx.doi.org/10.1016/j.joa.2017.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728706PMC
December 2017

Temporal Relationship of Asystole to Onset of Transient Loss of Consciousness in Tilt-Induced Reflex Syncope.

JACC Clin Electrophysiol 2017 12 13;3(13):1592-1598. Epub 2017 Sep 13.

Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Leiden, the Netherlands.

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http://dx.doi.org/10.1016/j.jacep.2017.07.006DOI Listing
December 2017

Ventricular fibrillation and long-QT syndrome due to panhypopituitarism.

J Cardiovasc Med (Hagerstown) 2017 10;18(10):833-834

aDepartment of Cardiology bDepartment of Radiology cDepartment of Neurology dDepartment of Biochemistry, Ospedali del Tigullio, Lavagna, Italy.

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http://dx.doi.org/10.2459/JCM.0000000000000531DOI Listing
October 2017

Vasovagal syncope with asystole: the role of cardiac pacing.

Clin Auton Res 2017 Aug 1;27(4):245-251. Epub 2017 Jul 1.

BIOTRONIK Italy S.p.A., Vimodrone, Italy.

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http://dx.doi.org/10.1007/s10286-017-0441-7DOI Listing
August 2017

Clinical Characteristics and Outcome of Patients with Situational Syncope Compared to Patients with Vasovagal Syncope.

Pacing Clin Electrophysiol 2017 May 23;40(5):591-595. Epub 2017 Mar 23.

Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

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http://dx.doi.org/10.1111/pace.13069DOI Listing
May 2017

Stop vasodepressor drugs in reflex syncope: a randomised controlled trial.

Heart 2017 03 23;103(6):449-455. Epub 2016 Sep 23.

Department of Cardiology, Arrhythmologic Center, Ospedali del Tigullio, Lavagna, Italy.

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http://dx.doi.org/10.1136/heartjnl-2016-309865DOI Listing
March 2017

Mechanism of syncope without prodromes with normal heart and normal electrocardiogram.

Heart Rhythm 2017 02 14;14(2):234-239. Epub 2016 Sep 14.

Department of Cardiology, Timone University Hospital, Marseille, France.

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http://dx.doi.org/10.1016/j.hrthm.2016.08.046DOI Listing
February 2017

The Role of the Baroreflex in Tilt Table Testing: Outcome and Type of Response.

JACC Clin Electrophysiol 2016 12 22;2(7):812-817. Epub 2016 Jun 22.

Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. Electronic address:

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http://dx.doi.org/10.1016/j.jacep.2016.05.001DOI Listing
December 2016

Long-Term Results After Single and Multiple Procedures of Ablation of Ventricular Tachycardia.

J Cardiovasc Electrophysiol 2016 Nov 25;27(11):1319-1324. Epub 2016 Aug 25.

Arrhythmology Centre, Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy.

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http://dx.doi.org/10.1111/jce.13061DOI Listing
November 2016

Syncope in patients paced for atrioventricular block.

Europace 2016 Nov 6;18(11):1735-1739. Epub 2016 Feb 6.

Arrhythmologic Centre, Department of Cardiology, Ospedali del Tigullio, Lavagna 16033, Italy

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http://dx.doi.org/10.1093/europace/euv425DOI Listing
November 2016

Long-Term Outcome of Patients with Bifascicular Block and Unexplained Syncope Following Cardiac Pacing.

Pacing Clin Electrophysiol 2016 Oct 22;39(10):1126-1131. Epub 2016 Sep 22.

Division of Cardiovascular Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

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http://dx.doi.org/10.1111/pace.12946DOI Listing
October 2016

The pathophysiologic mechanisms associated with hypotensive susceptibility.

Clin Auton Res 2016 08 20;26(4):261-8. Epub 2016 Jun 20.

Division of Cardiovascular Medicine, School of Medicine and Public Health, University of Wisconsin, H4/534 Clinical Science Center, 600 Highland Avenue, Madison, WI, 53792-3248, USA.

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http://dx.doi.org/10.1007/s10286-016-0362-xDOI Listing
August 2016

Finally, a Drug Proves to Be Effective Against Vasovagal Syncope!: But Not in All Patients.

Authors:
Michele Brignole

J Am Coll Cardiol 2016 07;68(1):10-2

Arrhythmologic Center & Syncope Unit, Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.03.595DOI Listing
July 2016

Efficacy of theophylline in patients affected by low adenosine syncope.

Heart Rhythm 2016 05 9;13(5):1151-1154. Epub 2015 Dec 9.

UMR MD2, Aix Marseille University, Marseille, France; Institute of Biological research of the French Army (IRBA), Marseille, France.

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http://www.sciencedirect.com/science/article/pii/S1547527115
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http://linkinghub.elsevier.com/retrieve/pii/S154752711501531
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http://dx.doi.org/10.1016/j.hrthm.2015.12.016DOI Listing
May 2016

Hyperoxia Improves Hemodynamic Status During Head-up Tilt Testing in Healthy Volunteers: A Randomized Study.

Medicine (Baltimore) 2016 Feb;95(8):e2876

From the UMR-MD2, Dysoxie Suractivité, Institut de Recherche Biomédicale des Armées (IRBA) & Aix-Marseille Université, Faculté de Médecine Nord, Marseille, France (JF, GC, J-CR, FJ, J-CD, RG, AB); Laboratoire HandiBio EA 4322, Université du Sud Toulon Var, La Garde, France (OG); Laboratoire de biomécanique appliquée, Aix Marseille Université, Faculté de Médecine Nord, Marseille, France (ML); and Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy (MB).

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http://dx.doi.org/10.1097/MD.0000000000002876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779018PMC
February 2016

Pacing for neurally-mediated syncope: How to decide?

Authors:
Michele Brignole

Cardiol J 2014 ;21(6):601-5

Arrhythmologic Center, Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy.

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http://dx.doi.org/10.5603/CJ.2014.0092DOI Listing
January 2016

Syncope and Idiopathic (Paroxysmal) AV Block.

Cardiol Clin 2015 Aug;33(3):441-7

Laboratory of Biochemistry and Molecular Biology, Timone University Hospital, Unité Mixte de Recherche Ministere de la Defense, Aix Marseille Université, Boulevard P Dramard, Marseille 13015, France.

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http://dx.doi.org/10.1016/j.ccl.2015.04.012DOI Listing
August 2015

Twenty-eight years of research permit reinterpretation of tilt-testing: hypotensive susceptibility rather than diagnosis.

Eur Heart J 2014 Sep 30;35(33):2211-2. Epub 2014 Jun 30.

Ospedali del Tigullio, Lavagna, GE, Italy.

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http://dx.doi.org/10.1093/eurheartj/ehu255DOI Listing
September 2014

Additional diagnostic value of implantable loop recorder in patients with initial diagnosis of real or apparent transient loss of consciousness of uncertain origin.

Europace 2014 Aug 25;16(8):1226-30. Epub 2014 Mar 25.

Dipartimento di Cardiologia, Ospedali del Tigullio, Centro Aritmologico, Lavagna, Italia Syncope Unit, Cardiologia e Medicina Geriatrica, AOU Careggi e Università di Firenze, Firenze, Italia.

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http://dx.doi.org/10.1093/europace/euu051DOI Listing
August 2014

Purinergic profile of fainting divers is different from patients with vasovagal syncope.

Int J Cardiol 2014 Jul 24;174(3):741-3. Epub 2014 Apr 24.

UMR MD2, AMU, Faculty of Medicine, Marseille, France; IRBA, France; Laboratory of Biochemistry, Timone University Hospital, AP-HM, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01675273140074
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http://dx.doi.org/10.1016/j.ijcard.2014.04.090DOI Listing
July 2014

Clinical context and outcome of carotid sinus syndrome diagnosed by means of the 'method of symptoms'.

Europace 2014 Jun 20;16(6):928-34. Epub 2013 Sep 20.

Arrhythmologic Centre and Syncope Unit, Department of Cardiology, Ospedali del Tigullio, Via Don Bobbio 25, 16033 Lavagna, Italy

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http://dx.doi.org/10.1093/europace/eut283DOI Listing
June 2014

Assessment of the vasodepressor reflex in carotid sinus syndrome.

Circ Arrhythm Electrophysiol 2014 Jun 24;7(3):505-10. Epub 2014 Apr 24.

From the Department of Cardiology, Arrhythmologic Center, Ospedali del Tigullio, Lavagna, Italy (D.S., R.M., D.O., A.S., F.C., P.D., M.B.); and Department of Internal Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands (W.W.).

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http://dx.doi.org/10.1161/CIRCEP.113.001093DOI Listing
June 2014

Risk of syncope during work.

Europace 2014 Feb 9;16(2):289-92. Epub 2013 Aug 9.

Divisione Cardiologia, Ospedale Villa Scassi, Genova ASL 3, Via Scassi, 1, 16100 Genova, Italy.

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http://dx.doi.org/10.1093/europace/eut247DOI Listing
February 2014

Syncope without prodromes in patients with normal heart and normal electrocardiogram: a distinct entity.

J Am Coll Cardiol 2013 Sep 27;62(12):1075-1080. Epub 2013 Jun 27.

Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2013.05.060DOI Listing
September 2013

2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: the Task Force on cardiac pacing and resynchronization therapy of the European Society of Cardiology (ESC). Developed in collaboration with the European Heart Rhythm Association (EHRA).

Eur Heart J 2013 Aug 24;34(29):2281-329. Epub 2013 Jun 24.

Department of Cardiology, Ospedali del Tigullio, Via Don Bobbio 25, IT-16033 Lavagna, (GE) Italy.

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http://dx.doi.org/10.1093/eurheartj/eht150DOI Listing
August 2013

Vagally mediated atrioventricular block: pathophysiology and diagnosis.

Heart 2013 Jul 2;99(13):904-8. Epub 2013 Jan 2.

Department of Medicine, Section of Cardiology, Ospedale Privato Quisisana, Viale Cavour 128, 44121 Ferrara, Italy.

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http://dx.doi.org/10.1136/heartjnl-2012-303220DOI Listing
July 2013

Standardized care pathway versus conventional approach in the management of patients presenting with faint at the University of Utah.

Pacing Clin Electrophysiol 2013 Feb 25;36(2):152-62. Epub 2012 Oct 25.

Division of Geriatrics, University of Utah Medical Center, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1111/pace.12033DOI Listing
February 2013

Key challenges in the current management of syncope.

Nat Rev Cardiol 2012 Oct 17;9(10):590-8. Epub 2012 Jul 17.

ICCH Building, 59-61 North Wharf Road, London W2 1LA, UK.

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http://dx.doi.org/10.1038/nrcardio.2012.102DOI Listing
October 2012

ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC.

Eur J Heart Fail 2012 Aug;14(8):803-69

Glasgow G12 8QQ, UK.

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http://eurheartj.oxfordjournals.org/content/ehj/33/14/1787.f
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http://doi.wiley.com/10.1093/eurjhf/hfs105
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http://dx.doi.org/10.1093/eurjhf/hfs105DOI Listing
August 2012

Restoring sinus rhythm results in blood pressure reduction in patients with persistent atrial fibrillation and a history of hypertension.

J Cardiovasc Electrophysiol 2012 Jul 11;23(7):722-6. Epub 2012 Apr 11.

Division of Geriatrics, University of Utah, Medical Center, Salt Lake City, Utah 84132, USA.

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http://dx.doi.org/10.1111/j.1540-8167.2011.02280.xDOI Listing
July 2012

New concepts in the assessment of syncope.

J Am Coll Cardiol 2012 May;59(18):1583-91

Arrhythmologic Centre and Syncope Unit, Ospedali del Tigullio, Lavagna, Italy.

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http://dx.doi.org/10.1016/j.jacc.2011.11.056DOI Listing
May 2012

Additional diagnostic value of very prolonged observation by implantable loop recorder in patients with unexplained syncope.

J Cardiovasc Electrophysiol 2012 Jan 21;23(1):67-71. Epub 2011 Jul 21.

Arrhythmologic Center, Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy.

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http://doi.wiley.com/10.1111/j.1540-8167.2011.02133.x
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http://dx.doi.org/10.1111/j.1540-8167.2011.02133.xDOI Listing
January 2012

Syncope in the emergency department: comparison of standardized admission criteria with clinical practice.

Europace 2011 Nov 14;13(11):1632-8. Epub 2011 Jul 14.

Division of Cardiology, Medical Center, University of Utah, Salt Lake City, UT 84132, USA.

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http://dx.doi.org/10.1093/europace/eur201DOI Listing
November 2011

Syncope due to idiopathic paroxysmal atrioventricular block: long-term follow-up of a distinct form of atrioventricular block.

J Am Coll Cardiol 2011 Jul 12;58(2):167-73. Epub 2011 May 12.

Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy.

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http://dx.doi.org/10.1016/j.jacc.2010.12.045DOI Listing
July 2011

Underevaluation of cardiovascular risk factors in patients with nonaccidental falls.

J Prim Care Community Health 2011 Jul 17;2(3):173-80. Epub 2011 May 17.

University of Utah Medical Center, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1177/2150131911405212DOI Listing
July 2011

Effect of clinical triggers on positive responses to tilt-table testing potentiated with nitroglycerin or clomipramine.

Am J Cardiol 2011 Jun 21;107(11):1693-7. Epub 2011 Mar 21.

Arrhythmologic Centre, Department of Cardiology, Ospedali del Tigullio, Lavagna, Italy.

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http://dx.doi.org/10.1016/j.amjcard.2011.01.057DOI Listing
June 2011

Effectiveness of remote monitoring in the management of syncope and palpitations.

Europace 2011 Mar 17;13(3):431-7. Epub 2011 Jan 17.

Department of Cardiology, Centro Aritmologico e Syncope Unit, Ospedali del Tigullio, 16033 Lavagna, Italy.

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http://dx.doi.org/10.1093/europace/euq503DOI Listing
March 2011

[2010 AIAC Guidelines for the management and treatment of atrial fibrillation].

G Ital Cardiol (Rome) 2011 Jan;12(1 Suppl 1):7-69

Dipartimento Cardiovascolare, Centro Aritmologico eper la Fibrillazione Atriale, Ospedale dell'Angelo, Mestre-Venezia.

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January 2011