Michele Baccarani

Michele Baccarani

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Michele Baccarani

Publications by authors named "Michele Baccarani"

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Chronic myeloid leukemia: the concepts of resistance and persistence and the relationship with the BCR-ABL1 transcript type.

Leukemia 2019 Aug 27. Epub 2019 Aug 27.

Institute of Hematology "Lorenzo and Ariosto Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine, S.Orsola-Malpighi University Hospital, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1038/s41375-019-0562-1DOI Listing
August 2019

The proportion of different BCR-ABL1 transcript types in chronic myeloid leukemia. An international overview.

Leukemia 2019 05 23;33(5):1173-1183. Epub 2019 Jan 23.

Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie (IBE), Ludwig-Maximilians-Universität München, Munich, Germany.

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http://www.nature.com/articles/s41375-018-0341-4
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http://dx.doi.org/10.1038/s41375-018-0341-4DOI Listing
May 2019

Physicians' attitude towards selection of second line therapy with nilotinib and dasatinib in chronic myeloid leukemia patients.

Health Qual Life Outcomes 2017 Oct 18;15(1):204. Epub 2017 Oct 18.

Italian Group for Adult Hematologic Diseases (GIMEMA), Data Center and Health Outcomes Research Unit, Rome, Italy.

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http://dx.doi.org/10.1186/s12955-017-0788-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648464PMC
October 2017

Systematic review and meta-analysis of standard-dose imatinib vs. high-dose imatinib and second generation tyrosine kinase inhibitors for chronic myeloid leukemia.

J Cancer Res Clin Oncol 2017 Jul 8;143(7):1311-1318. Epub 2017 Mar 8.

Medizinische Fakultaet Mannheim, Universität Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00432-017-2385-7DOI Listing
July 2017

New strategies in myelofibrosis: the evolving paradigm of disease pathogenesis, prognostication and treatment.

Hematol Oncol 2017 Jun 10;35(2):145-150. Epub 2016 Aug 10.

Department of Hematology and Oncology "L. and A. Seràgnoli", Sant'Orsola-Malpighi University Hospital, Via Massarenti 9, 40138, Bologna, Italy.

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http://dx.doi.org/10.1002/hon.2324DOI Listing
June 2017

Tyrosine kinase inhibitors in chronic myeloid leukaemia: which, when, for whom?

Nat Rev Clin Oncol 2017 03 18;14(3):141-154. Epub 2016 Oct 18.

Institute of Haematology and Medical Oncology Lorenzo ed Ariosto Seràgnoli, Department of Experimental, Diagnostic and Specialty Medicine, Bologna University School of Medicine, S.Orsola-Malpighi University Hospital, Via Massarenti 9, 40138 Bologna, Italy.

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http://dx.doi.org/10.1038/nrclinonc.2016.139DOI Listing
March 2017

Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia.

N Engl J Med 2017 03;376(10):917-927

From Abteilung Hämatologie-Onkologie, Universitätsklinikum Jena, Jena, Germany (A.H.); the Department of Medicine, University of Chicago, Chicago (R.A.L.); INSERM Centre d'Investigation Clinique 1402, Centre Hospitalier Universitaire de Poitiers, Poitiers, France (F.G.); Fred Hutchinson Cancer Research Center, Seattle (J.P.R.); Centre for Cancer Biology, SA Pathology, University of South Australia and University of Adelaide (S.B.), and the South Australian Health and Medical Research Institute and University of Adelaide (T.P.H.), Adelaide, SA, Australia; University of Bologna, Bologna, Italy (M.B.); the University of Utah Huntsman Cancer Institute, Salt Lake City (M.W.D.); the Hematology Department, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona (F.C.); Novartis, Basel, Switzerland (S.F., C.-E.O., H.D.M.); M.D. Anderson Cancer Center, Houston (H.K.); the University of Newcastle, Newcastle, United Kingdom (S.G.O.); and Knight Cancer Institute, Oregon Health and Science University and Howard Hughes Medical Institute, Portland (B.J.D.).

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http://dx.doi.org/10.1056/NEJMoa1609324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901965PMC
March 2017

Psychological well-being and social support in chronic myeloid leukemia patients receiving lifelong targeted therapies.

Support Care Cancer 2016 12 23;24(12):4887-4894. Epub 2016 Jul 23.

Department of Hematology-Oncology, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy.

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http://dx.doi.org/10.1007/s00520-016-3344-6DOI Listing
December 2016

Nilotinib against high dose imatinib for salvage therapy of chronic myeloid leukaemia.

Lancet Haematol 2016 12;3(12):e554-e555

University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1016/S2352-3026(16)30170-3DOI Listing
December 2016

Impact of dose intensity of ponatinib on selected adverse events: Multivariate analyses from a pooled population of clinical trial patients.

Leuk Res 2016 09 22;48:84-91. Epub 2016 Jul 22.

ARIAD Pharmaceuticals, Inc., 26 Landsdowne Street, Cambridge, MA, 02139-4234, USA. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2016.07.007DOI Listing
September 2016

Management of pregnant chronic myeloid leukemia patients.

Expert Rev Hematol 2016 Aug 7;9(8):781-91. Epub 2016 Jul 7.

b Department of Hematology & Oncology 'L. and A. Seràgnoli' , S.Orsola-Malpighi University Hospital , Bologna , Italy.

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http://dx.doi.org/10.1080/17474086.2016.1205479DOI Listing
August 2016

Assessment of Minimal Residual Disease in Standard-Risk AML.

N Engl J Med 2016 08;375(6):e9

University of Bologna, Bologna, Italy

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http://dx.doi.org/10.1056/NEJMc1603847DOI Listing
August 2016

Cost-effectiveness of Tyrosine Kinase Inhibitor Treatment Strategies for Chronic Myeloid Leukemia in Chronic Phase After Generic Entry of Imatinib in the United States.

J Natl Cancer Inst 2016 Jul 4;108(7). Epub 2016 Mar 4.

Affiliations of authors:Department of Health Policy and Management, Johns Hopkins University , Baltimore, MD (WVP); Department of Medicine (RAL) and Departments of Pediatrics and of Public Health Sciences (RMC), University of Chicago, Chicago, IL; Eshelman School of Pharmacy and Gillings School of Global Public Health, Lineberger Comprehensive Cancer Center , and Cecil G. Sheps Center for Health Services Research, University of North Carolina , Chapel Hill, NC (SBD); Department of Haematology, Hammersmith Hospital, Imperial College , London , UK (JFA); Department of Medicine (RH, SS) and Department of Hematology and Oncology (MCM), University of Heidelberg, Mannheim, Germany; Department of Haematology and Oncology, S. Orsola-Malpighi University Hospital (MB), and Department of Hematology, "L. e A. Seragnoli" (GM), University of Bologna , Bologna , Italy ; Department of Haematology and Oncology, University Hospital , Jena , Germany (EE); INSERM Centre d'Investigation Clinique (CIC) 1402, CHU de Poitiers, Poitiers, France (JG, FG); Laboratoire d'Hematologie, Universite Victor Segalen, Bordeaux, Pessac, France (FXM); Department of Internal Medicine, Hematology and Oncology, University Hospital Brno , Brno , Czech Republic (JM); Department of Hematology and Oncology, University Hospital Leipzig , Leipzig , Germany (DN); Barbara Ann Karmanos Cancer Institute, Wayne State University , Detroit, MI (CAS); Department of Medicine, Weill Cornell Medical Center , New York, NY (RTS); Uppsala University , Uppsala , Sweden (BS).

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http://dx.doi.org/10.1093/jnci/djw003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948567PMC
July 2016

Final 5-Year Study Results of DASISION: The Dasatinib Versus Imatinib Study in Treatment-Naïve Chronic Myeloid Leukemia Patients Trial.

J Clin Oncol 2016 07 23;34(20):2333-40. Epub 2016 May 23.

Jorge E. Cortes and Hagop M. Kantarjian The University of Texas MD Anderson Cancer Center, Houston, TX; Neil P. Shah, University of California San Francisco School of Medicine, San Francisco, CA; Brigid Bradley-Garelik and George Manos, Bristol-Myers Squibb, Princeton, NJ; Giuseppe Saglio, University of Turin, Turin; Michele Baccarani, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy; Jiří Mayer, University Hospital Brno and Central European Institute of Technology, Masaryk University, Brno, Czech Republic; Concepción Boqué, Institut Català d'Oncologia, Hospital Duran i Reynals, L'Hospitalet, Barcelona, Spain; Charles Chuah, Singapore General Hospital, Duke-National University of Singapore Medical School, Singapore; Luis Casanova, Instituto Nacional de Enfermedades Neoplásicas, Lima, Perú;and Andreas Hochhaus, Universitätsklinikum Jena, Jena, Germany.

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http://dx.doi.org/10.1200/JCO.2015.64.8899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118045PMC
July 2016

Tyrosine kinase inhibitors in Ph+ acute lymphoblastic leukaemia: facts and perspectives.

Ann Hematol 2016 Apr 19;95(5):681-93. Epub 2016 Feb 19.

Department of Hematology/Oncology "L. and A. Seràgnoli", S. Orsola-Malpighi University Hospital, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1007/s00277-016-2617-yDOI Listing
April 2016

Compound mutations in BCR-ABL1 are not major drivers of primary or secondary resistance to ponatinib in CP-CML patients.

Blood 2016 Feb 24;127(6):703-12. Epub 2015 Nov 24.

Department of Genetics and Molecular Pathology, SA Pathology, Centre for Cancer Biology, School of Medicine and School of Molecular and Biomedical Science, University of Adelaide, Adelaide, Australia; and School of Pharmacy and Medical Science, University of South Australia, Adelaide, Australia.

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http://dx.doi.org/10.1182/blood-2015-08-660977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760131PMC
February 2016

Molecular monitoring and mutations in chronic myeloid leukemia: how to get the most out of your tyrosine kinase inhibitor.

Am Soc Clin Oncol Educ Book 2014 :167-75

From the Department of Hematology-Oncology 'L. and A. Seràgnoli', and the Department of Experimental, Diagnostic, and Specialty Medicine, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.14694/EdBook_AM.2014.34.167DOI Listing
November 2015

Managing children with chronic myeloid leukaemia.

Br J Haematol 2015 Jun 27;169(5):759-60. Epub 2014 Nov 27.

ELN and GIMEMA CML Working Parties, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1111/bjh.13250DOI Listing
June 2015

Bortezomib-based therapy for mantle-cell lymphoma.

N Engl J Med 2015 06;372(23):2270

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http://dx.doi.org/10.1056/NEJMc1504240DOI Listing
June 2015

A review of the European LeukemiaNet recommendations for the management of CML.

Ann Hematol 2015 Apr 27;94 Suppl 2:S141-7. Epub 2015 Mar 27.

Department of Hematology and Oncology "L. and A. Seràgnoli", University of Bologna, S. Orsola-Malpighi University Hospital, Bologna, Italy.

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http://dx.doi.org/10.1007/s00277-015-2322-2DOI Listing
April 2015

A risk prediction score for invasive mold disease in patients with hematological malignancies.

PLoS One 2013 26;8(9):e75531. Epub 2013 Sep 26.

Institute of Hematology, Department of Hematology and Clinical Oncology, "Lorenzo e Ariosto Seràgnoli" S'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0075531PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784450PMC
July 2014

Current management of CML patients: Summary of the Italian Consensus Meeting held in Rome, April 11-12, 2013.

Crit Rev Oncol Hematol 2014 Jun 17;90(3):181-9. Epub 2013 Dec 17.

Division of Hematology and Internal Medicine, Department of Clinical and Biological Sciences of the University of Turin, Orbassano, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2013.12.010DOI Listing
June 2014

Definition and treatment of resistance to tyrosine kinase inhibitors in chronic myeloid leukemia.

Expert Rev Hematol 2014 Jun 25;7(3):397-406. Epub 2014 Mar 25.

Department of Hematology and Oncology "L. and A. Seràgnoli", Bologna, Italy.

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http://dx.doi.org/10.1586/17474086.2014.900432DOI Listing
June 2014

First-line treatment of newly diagnosed elderly patients with chronic myeloid leukemia: current and emerging strategies.

Drugs 2014 Apr;74(6):627-43

Institute of Hematology "L. e A. Seragnòli", Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, S.Orsola-Malpighi Hospital, Via Massarenti 9, 40138, Bologna, Italy,

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http://dx.doi.org/10.1007/s40265-014-0207-7DOI Listing
April 2014

Molecular monitoring.

Curr Hematol Malig Rep 2014 Mar;9(1):1-8

Department of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology "L. e A. Seràgnoli", University of Bologna, Via Massarenti 9, 40138, Bologna, Italy,

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http://dx.doi.org/10.1007/s11899-013-0192-zDOI Listing
March 2014

Treatment recommendations for chronic myeloid leukemia.

Mediterr J Hematol Infect Dis 2014 Jan 2;6(1):e2014005. Epub 2014 Jan 2.

Institute of Hematology "L. and A. Seràgnoli", Department of Specialty, Diagnostic and Experimental Medicine, University of Bologna, S.Orsola-Malpighi University Hospital, Bologna, Italy.

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http://dx.doi.org/10.4084/MJHID.2014.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894838PMC
January 2014

A critical history of chromic myeloid leukemia.

Mediterr J Hematol Infect Dis 2014 Jan 2;6(1):e2014010. Epub 2014 Jan 2.

University of Naples "Federico II" and CEINGE Biotecnologie Avanzate, Naples, Italy.

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http://dx.doi.org/10.4084/MJHID.2014.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894841PMC
January 2014

Impact of comorbidities on the treatment of chronic myeloid leukemia with tyrosine-kinase inhibitors.

Expert Rev Hematol 2013 Oct 2;6(5):563-74. Epub 2013 Oct 2.

Department of Experimental, Diagnostic and Specialty Medicine, S.Orsola-Malpighi Hospital, University of Bologna, Institute of Hematology "L. e A. Seragnòli", Bologna, Italy.

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http://dx.doi.org/10.1586/17474086.2013.837279DOI Listing
October 2013

Nilotinib population pharmacokinetics and exposure-response analysis in patients with imatinib-resistant or -intolerant chronic myeloid leukemia.

Eur J Clin Pharmacol 2013 Apr 5;69(4):813-23. Epub 2012 Oct 5.

HRB Clinical Research Facility, Galway, and Trinity College, National University of Ireland, Dublin, Ireland.

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http://dx.doi.org/10.1007/s00228-012-1385-4DOI Listing
April 2013

Decreased expression of indoleamine 2,3-dioxygenase 1 in dendritic cells contributes to impaired regulatory T cell development in immune thrombocytopenia.

Ann Hematol 2013 Jan 31;92(1):67-78. Epub 2012 Aug 31.

Institute of Hematology, Department of Hematology and Oncological Sciences L. e A. Seràgnoli, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1007/s00277-012-1556-5DOI Listing
January 2013

Advances in treatment of chronic myeloid leukemia with tyrosine kinase inhibitors: the evolving role of Bcr-Abl mutations and mutational analysis.

Pharmacogenomics 2012 Aug;13(11):1271-84

Department of Hematology/Oncology L. e A. Seragnoli, S. Orsola-Malpighi Hospital, Via Massarenti 9, 40138, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.2217/pgs.12.103DOI Listing
August 2012

Cytogenetic and molecular predictors of outcome in acute lymphocytic leukemia: recent developments.

Curr Hematol Malig Rep 2012 Jun;7(2):133-43

Department of Hematology and Oncological Sciences L. and A. Seràgnoli, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1007/s11899-012-0122-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3342501PMC
June 2012

Romiplostim as early treatment of immune thrombocytopenia with severe immunodeficiency.

Hematol Rep 2012 May 26;4(2):e10. Epub 2012 Jun 26.

Department of Hematology and Oncology L. e A. Seràgnoli, St. Orsola-Malpighi Hospital, University of Bologna;

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http://www.pagepress.org/journals/index.php/hr/article/view/
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http://dx.doi.org/10.4081/hr.2012.e10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401131PMC
May 2012

Long-term results of thalidomide and dexamethasone (thal-dex) as therapy of first relapse in multiple myeloma.

Ann Hematol 2012 Mar 8;91(3):419-26. Epub 2011 Sep 8.

"Seràgnoli" Institute of Hematology, Bologna University School of Medicine, Bologna, Italy.

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http://dx.doi.org/10.1007/s00277-011-1320-2DOI Listing
March 2012

Computed tomographic pulmonary angiography for diagnosis of invasive mold diseases in patients with hematological malignancies.

Clin Infect Dis 2012 Mar 4;54(5):610-6. Epub 2012 Feb 4.

Institute of Hematology Lorenzo e Ariosto Seràgnoli, Department of Hematology and Oncology, Sant'Orsola-Malpighi Hospital, University of Bologna, Italy.

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http://dx.doi.org/10.1093/cid/cir861DOI Listing
March 2012

Imatinib in chronic myeloid leukemia elderly patients.

Aging (Albany NY) 2011 Dec;3(12):1125-6

Department of Hematology and Clinical Oncology "Seràgnoli", S.Orsola-Malpighi Hospital, University of Bologna, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273892PMC
http://dx.doi.org/10.18632/aging.100420DOI Listing
December 2011