Publications by authors named "Michela Deleidi"

30Publications

Redefining Microglial Identity in Health and Disease at Single-Cell Resolution.

Trends Mol Med 2020 Sep 29. Epub 2020 Sep 29.

German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany; Department of Neurodegenerative Diseases, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2020.09.001DOI Listing
September 2020

Insights into GBA Parkinson's disease pathology and therapy with induced pluripotent stem cell model systems.

Neurobiol Dis 2019 07 31;127:1-12. Epub 2019 Jan 31.

German Center for Neurodegenerative Diseases (DZNE), 72076 Tübingen, Germany; Center of Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, 72076 Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.01.023DOI Listing
July 2019

The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson's Disease.

Cell Rep 2018 06;23(10):2976-2988

German Center for Neurodegenerative Diseases (DZNE), Helmholtz Association, Tübingen 72076, Germany; Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen 72076, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.05.009DOI Listing
June 2018

The GBAP1 pseudogene acts as a ceRNA for the glucocerebrosidase gene GBA by sponging miR-22-3p.

Sci Rep 2017 10 5;7(1):12702. Epub 2017 Oct 5.

Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini, Pieve Emanuele, Milan, 20090, Italy.

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http://dx.doi.org/10.1038/s41598-017-12973-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629250PMC
October 2017

Mitochondrial Antigen Presentation: A Vacuolar Path to Autoimmunity in Parkinson's Disease.

Trends Immunol 2016 11 13;37(11):719-721. Epub 2016 Sep 13.

German Centre for Neurodegenerative Diseases (DZNE) Tübingen within the Helmholtz Association, Tübingen, Germany; Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.it.2016.08.016DOI Listing
November 2016

Genome editing in pluripotent stem cells: research and therapeutic applications.

Biochem Biophys Res Commun 2016 05 27;473(3):665-74. Epub 2016 Feb 27.

Department of Microbiology and Immunology, School of Medicine and Biomedical Sciences, University at Buffalo, New York, USA.

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http://dx.doi.org/10.1016/j.bbrc.2016.02.113DOI Listing
May 2016

Immune aging, dysmetabolism, and inflammation in neurological diseases.

Front Neurosci 2015 3;9:172. Epub 2015 Jun 3.

Department of Internal Medicine II, Center for Medical Research, University of Tübingen Tübingen, Germany.

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http://dx.doi.org/10.3389/fnins.2015.00172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453474PMC
June 2015

Successful function of autologous iPSC-derived dopamine neurons following transplantation in a non-human primate model of Parkinson's disease.

Cell Stem Cell 2015 Mar 26;16(3):269-74. Epub 2015 Feb 26.

Neuroregeneration Research Institute, McLean Hospital and Harvard Medical School, Belmont, MA 02478, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2015.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462124PMC
March 2015

Concise review: modeling multiple sclerosis with stem cell biological platforms: toward functional validation of cellular and molecular phenotypes in inflammation-induced neurodegeneration.

Stem Cells Transl Med 2015 Mar 15;4(3):252-60. Epub 2015 Jan 15.

Multiple Sclerosis Center and Laboratory for Neural Stem Cells, Departments of Neurology and Neuroscience, The Ohio State University College of Medicine Wexner Medical Center, Columbus, Ohio, USA; Department of Neurodegenerative Diseases and German Center for Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany; Department of Neurology and Immunobiology, Yale School of Medicine, New Haven, Connecticut, USA; Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA; Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya, Institut de Recerca Vall d'Hebron, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain

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http://dx.doi.org/10.5966/sctm.2014-0133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339849PMC
March 2015

iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis.

Nat Commun 2014 Jun 6;5:4028. Epub 2014 Jun 6.

1] Department of Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE), Tübingen 72076, Germany [2] Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen 72076, Germany.

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http://dx.doi.org/10.1038/ncomms5028DOI Listing
June 2014

Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis.

PLoS One 2013 24;8(6):e68519. Epub 2013 Jun 24.

Emmy Noether-Group for Stem Cell Biology, Department of Molecular Embryology, Institute of Anatomy and Cell Biology, University of Freiburg, Freiburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0068519PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691147PMC
February 2014

The role of inflammation in sporadic and familial Parkinson's disease.

Cell Mol Life Sci 2013 Nov 12;70(22):4259-73. Epub 2013 May 12.

German Center for Neurodegenerative Diseases (DZNE), Otfried-Müller. Str 27, 72076, Tübingen, Germany,

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http://dx.doi.org/10.1007/s00018-013-1352-yDOI Listing
November 2013

Protein clearance mechanisms of alpha-synuclein and amyloid-Beta in lewy body disorders.

Int J Alzheimers Dis 2012 22;2012:391438. Epub 2012 Oct 22.

German Center for Neurodegenerative Diseases (DZNE), University of Tuebingen, 72076 Tuebingen, Germany.

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http://dx.doi.org/10.1155/2012/391438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485523PMC
November 2012

Viral and inflammatory triggers of neurodegenerative diseases.

Sci Transl Med 2012 Feb;4(121):121ps3

Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/scitranslmed.3003492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982831PMC
February 2012

Oct4-induced reprogramming is required for adult brain neural stem cell differentiation into midbrain dopaminergic neurons.

PLoS One 2011 31;6(5):e19926. Epub 2011 May 31.

Center for Neuroregeneration Research, Harvard Medical School/McLean Hospital, Belmont, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019926PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3104995PMC
October 2011

Development of histocompatible primate-induced pluripotent stem cells for neural transplantation.

Stem Cells 2011 Jul;29(7):1052-63

Center for Neuroregeneration Research, Harvard Medical School/McLean Hospital, Belmont, Massachusetts 02478, USA.

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http://dx.doi.org/10.1002/stem.662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340906PMC
July 2011

The Toll-like receptor-3 agonist polyinosinic:polycytidylic acid triggers nigrostriatal dopaminergic degeneration.

J Neurosci 2010 Dec;30(48):16091-101

Center for Neuroregeneration Research, Harvard Medical School/McLean Hospital, Belmont, Massachusetts, 02478, USA.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.2400-10.2
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http://dx.doi.org/10.1523/JNEUROSCI.2400-10.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075577PMC
December 2010

Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid.

Mol Cell Neurosci 2010 Nov 24;45(3):258-66. Epub 2010 Jul 24.

Neuroregeneration Laboratories, Harvard Medical School/McLean Hospital, NINDS Udall Parkinson's Disease Research Center of Excellence, 115 Mill Street, Belmont, MA 02478, USA.

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http://dx.doi.org/10.1016/j.mcn.2010.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945816PMC
November 2010

Neural stem cells and their use as therapeutic tool in neurological disorders.

Brain Res Brain Res Rev 2005 Apr 20;48(2):211-9. Epub 2005 Jan 20.

Department of Neuroscience, San Raffaele Scientific Institute, Neuroimmunology Unit-DIBIT, Milano, Italy.

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http://dx.doi.org/10.1016/j.brainresrev.2004.12.011DOI Listing
April 2005