Publications by authors named "Michel Mittelbronn"

100Publications

Cetuximab-Mediated Protection from Hypoxia- Induced Cell Death: Implications for Therapy Sequence in Colorectal Cancer.

Cancers (Basel) 2020 Oct 20;12(10). Epub 2020 Oct 20.

Dr. Senckenberg Institute of Neurooncology, University Hospital Frankfurt, Goethe University, 60528 Frankfurt am Main, Germany.

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http://dx.doi.org/10.3390/cancers12103050DOI Listing
October 2020

Linking epigenetic signature and metabolic phenotype in IDH mutant and IDH wildtype diffuse glioma.

Neuropathol Appl Neurobiol 2020 Oct 20. Epub 2020 Oct 20.

Neurological Institute (Edinger-Institute), University Hospital, Goethe University Frankfurt am Main, Frankfurt, Germany.

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http://dx.doi.org/10.1111/nan.12669DOI Listing
October 2020

Cholinergic innervation and ganglion cell distribution in Hirschsprung's disease.

BMC Pediatr 2020 Aug 24;20(1):399. Epub 2020 Aug 24.

Institute of Neurology (Edinger Institute), Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.1186/s12887-020-02299-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445925PMC
August 2020

High density DNA methylation array is a reliable alternative for PCR-based analysis of the MGMT promoter methylation status in glioblastoma.

Pathol Res Pract 2020 Jan 11;216(1):152728. Epub 2019 Nov 11.

Institute of Neurology (Edinger Institute), Goethe University, Frankfurt, Germany; NORLUX Neuro-Oncology Laboratory, Luxembourg Institute of Health (LIH), Luxembourg; Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Luxembourg; National Center of Pathology (NCP), Laboratoire national de santé (LNS), Dudelange, Luxembourg; Luxembourg Centre of Neuropathology (LCNP), Luxembourg. Electronic address:

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http://dx.doi.org/10.1016/j.prp.2019.152728DOI Listing
January 2020

Delay in diagnosing patients with right-sided glioblastoma induced by hemispheric-specific clinical presentation.

J Neurooncol 2020 Jan 11;146(1):63-69. Epub 2019 Nov 11.

Department of Neurology, Goethe University, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s11060-019-03335-4DOI Listing
January 2020

Mistletoe-Based Drugs Work in Synergy with Radio-Chemotherapy in the Treatment of Glioma and in Glioblastoma Bearing Mice.

Evid Based Complement Alternat Med 2019 3;2019:1376140. Epub 2019 Jul 3.

Molecular Neurooncology, Hertie Institute for Clinical Brain Research and Center Neurology, University of Tübingen, Otfried-Müller-Str. 27, 72076 Tübingen, Germany.

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https://www.hindawi.com/journals/ecam/2019/1376140/
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http://dx.doi.org/10.1155/2019/1376140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636536PMC
July 2019

Therapeutic Targeting of Stat3 Using Lipopolyplex Nanoparticle-Formulated siRNA in a Syngeneic Orthotopic Mouse Glioma Model.

Cancers (Basel) 2019 Mar 8;11(3). Epub 2019 Mar 8.

Experimental Neurosurgery, Department of Neurosurgery, Neuroscience Center, Goethe University Hospital, 60528 Frankfurt am Main, Germany.

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http://dx.doi.org/10.3390/cancers11030333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468565PMC
March 2019

Pontine tumor in a neonate: case report and analysis of the current literature.

J Neurosurg Pediatr 2019 Feb 15:1-7. Epub 2019 Feb 15.

1Pediatric Hematology and Oncology, Goethe University; Departments of.

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http://dx.doi.org/10.3171/2018.10.PEDS18215DOI Listing
February 2019

The physiological mTOR complex 1 inhibitor DDIT4 mediates therapy resistance in glioblastoma.

Br J Cancer 2019 03 12;120(5):481-487. Epub 2019 Feb 12.

Dr. Senckenberg Institute of Neurooncology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.

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http://www.nature.com/articles/s41416-018-0368-3
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http://dx.doi.org/10.1038/s41416-018-0368-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461855PMC
March 2019

Adjuvant Therapy Using Mistletoe Containing Drugs Boosts the T-Cell-Mediated Killing of Glioma Cells and Prolongs the Survival of Glioma Bearing Mice.

Evid Based Complement Alternat Med 2018 27;2018:3928572. Epub 2018 Aug 27.

Molecular Neuro-Oncology, Hertie Institute for Clinical Brain Research and Center Neurology, University of Tübingen, Otfried-Müller-Str. 27, 72076 Tübingen, Germany.

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https://www.hindawi.com/journals/ecam/2018/3928572/
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http://dx.doi.org/10.1155/2018/3928572DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6129785PMC
August 2018

Microglia in Health and Disease: A Unique Immune Cell Population.

Front Immunol 2018 15;9:1779. Epub 2018 Aug 15.

School of Biological Sciences, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.3389/fimmu.2018.01779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104119PMC
September 2019

EGFL7 enhances surface expression of integrin αβ to promote angiogenesis in malignant brain tumors.

EMBO Mol Med 2018 09;10(9)

Molecular Signal Transduction Laboratories, Institute for Microscopic Anatomy and Neurobiology, Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn), University Medical Center of the Johannes Gutenberg University, Mainz, Germany

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http://dx.doi.org/10.15252/emmm.201708420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127886PMC
September 2018

Pre- and early postoperative GFAP serum levels in glioma and brain metastases.

J Neurooncol 2018 Sep 24;139(3):541-546. Epub 2018 May 24.

Department of Neurosurgery, University Hospital, Goethe University Frankfurt, 60528, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s11060-018-2898-1DOI Listing
September 2018

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature26000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093218PMC
March 2018

New MR perfusion features in primary central nervous system lymphomas: pattern and prognostic impact.

J Neurol 2018 Mar 30;265(3):647-658. Epub 2018 Jan 30.

Institute of Neuroradiology, Goethe-University Hospital Frankfurt, Schleusenweg 2-16, 60528, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s00415-018-8737-7DOI Listing
March 2018

An advanced glioma cell invasion assay based on organotypic brain slice cultures.

BMC Cancer 2018 01 30;18(1):103. Epub 2018 Jan 30.

Division of Signal Transduction and Growth Control, DKFZ/ZMBH Alliance, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s12885-018-4007-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789681PMC
January 2018

Suppression of oxidative phosphorylation confers resistance against bevacizumab in experimental glioma.

J Neurochem 2018 02 8;144(4):421-430. Epub 2018 Jan 8.

Dr Senckenberg Institute of Neurooncology, Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.1111/jnc.14264DOI Listing
February 2018

Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway.

Mol Cell 2017 Nov;68(4):786-796.e6

Institute of Biochemistry II, Medical School Goethe University, Frankfurt, Germany; Munich Cluster for Systems Neurology, Medical Faculty, Ludwig-Maximilians-Universität München, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.10.029DOI Listing
November 2017

ASA404, a vascular disrupting agent, as an experimental treatment approach for brain tumors.

Oncol Lett 2017 Nov 28;14(5):5443-5451. Epub 2017 Aug 28.

Institute of Neurology (Edinger-Institute), Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.3892/ol.2017.6832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652230PMC
November 2017

Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors.

Int J Oncol 2017 Aug 21;51(2):702-714. Epub 2017 Jun 21.

Molecular Neuro-Oncology, Hertie Institute for Clinical Brain Research and Center Neurology, University of Tübingen, D-72076 Tübingen, Germany.

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http://dx.doi.org/10.3892/ijo.2017.4051DOI Listing
August 2017

Bevacizumab for Patients with Recurrent Gliomas Presenting with a Gliomatosis Cerebri Growth Pattern.

Int J Mol Sci 2017 Mar 29;18(4). Epub 2017 Mar 29.

Dr. Senckenberg Institute of Neurooncology, Goethe University, 60528 Frankfurt, Germany.

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http://dx.doi.org/10.3390/ijms18040726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412312PMC
March 2017

Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function.

Circulation 2017 Jul 28;136(1):65-79. Epub 2017 Mar 28.

From Institute for Cardiovascular Physiology (M.S.L., C.F., I.J., M.J.M., J.E., F.M., R.P.B.), Functional Proteomics, SFB 815 Core Unit, Faculty of Medicine (F.M.R., J.H., I.W.), Institute of Vascular Signalling (J.H.), Institute of Cardiovascular Regeneration (P.H. Y.P., S.U., K.S., R.A.B., S.D.), Department of Neurosurgery (T.M.F.), Pharmazentrum Frankfurt, Institute of General Pharmacology and Toxicology (K.D.), Goethe University, Germany; ECCPS Bioinformatics and Sequencing Facility (J.P., S.G., C.K., M.L.) and Department of Lung Development and Remodeling (C.V., S.S.P.), Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany; Institute of Neurology (K.H.P., M.M., K.D.); Department of Vascular and Endovascular Surgery, Klinikum Rechts der Isar, Technical University Munich, Germany (L.M.); Luxembourg Centre of Neuropathology (M.M.); Laboratoire National de Santé, Dudelange, Luxembourg (M.M.); Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette (M.M.); NORLUX Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health (M.M.); Cardiovascular Innovation Institute, University of Louisville, KY (S.U.); Department of Internal Medicine, Member of the German Center for Lung Research (DZL), Justus-Liebig University, Giessen, Germany (R.T.S., N.W., S.S.P.); Department of Medicine, Duke University and Durham VA Medical Center, NC (F.J.M.); and German Center of Cardiovascular Research (DZHK), Partner Site RheinMain, Frankfurt, Germany (M.S.L., C.F., I.J., J.H., J.E., P.H., F.M., Y.P., K.H.P., K.S., I.W., R.A.B., S.D., R.P.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491227PMC
July 2017

Secondary Glioblastoma: Molecular and Clinical Factors That Affect Outcome After Malignant Progression of a Lower Grade Tumor.

World Neurosurg 2017 Jun 2;102:49-55. Epub 2017 Mar 2.

Department of Neurosurgery, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.wneu.2017.02.104DOI Listing
June 2017

Viscumins functionally modulate cell motility-associated gene expression.

Int J Oncol 2017 Feb 3;50(2):684-696. Epub 2017 Jan 3.

Molecular Neuro-Oncology, Hertie Institute for Clinical Brain Research and Center Neurology, University of Tübingen, D-72076 Tübingen, Germany.

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https://www.spandidos-publications.com/10.3892/ijo.2017.3838
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http://dx.doi.org/10.3892/ijo.2017.3838DOI Listing
February 2017

Identification of intestinal ganglioneuromatosis leads to early diagnosis of MEN2B: role of rectal biopsy.

J Pediatr Surg 2017 Jul 17;52(7):1161-1165. Epub 2016 Nov 17.

Department of Pediatric Surgery and Pediatric Urology, Goethe University Hospital, Frankfurt, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jpedsurg.2016.10.054DOI Listing
July 2017

Brain invasion in otherwise benign meningiomas does not predict tumor recurrence.

Acta Neuropathol 2016 09 27;132(3):479-81. Epub 2016 Jul 27.

Edinger Institute, Institute of Neurology, Goethe University Frankfurt, 60528, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s00401-016-1598-1DOI Listing
September 2016

The Cytosolic NADPH Oxidase Subunit NoxO1 Promotes an Endothelial Stalk Cell Phenotype.

Arterioscler Thromb Vasc Biol 2016 08 9;36(8):1558-65. Epub 2016 Jun 9.

From the Institute for Cardiovascular Physiology (R.P.B., S.H., C.S., I.J., B.R., F.R., O.L., F.M., J.E., K.S.), Pharmazentrum Frankfurt (J.E.), Institute for Biochemistry II (A.N.), and Neurological Institute (Edinger Institute) (C.P., M.M.), Goethe University, Frankfurt, Germany; Department of Physiology, Medical Faculty, TU Dresden, Dresden, Germany (I.K.); Justus-Liebig Universität Giessen, Giessen, Germany (N.W.); and German Center for Cardiovascular Research (DZHK), Partner Site RheinMain, Frankfurt, Germany (R.P.B., C.S., I.J., F.R., O.L., F.M., K.S.).

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http://dx.doi.org/10.1161/ATVBAHA.116.307132DOI Listing
August 2016

Pbx1 is required for adult subventricular zone neurogenesis.

Development 2016 07 25;143(13):2281-91. Epub 2016 May 25.

Institute of Neurology (Edinger Institute), J. W. Goethe University Medical School, German Cancer Consortium (DKTK), Heinrich-Hoffmann Str. 7, Frankfurt D-60528, Germany

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http://dx.doi.org/10.1242/dev.128033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958316PMC
July 2016

Prognostic factors in recurrent glioblastoma patients treated with bevacizumab.

J Neurooncol 2016 08 18;129(1):93-100. Epub 2016 May 18.

Dr. Senckenberg Institute of Neurooncology, University Hospital Frankfurt, Goethe University, Schleusenweg 2-16, 60528, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s11060-016-2144-7DOI Listing
August 2016

Downstream effects of plectin mutations in epidermolysis bullosa simplex with muscular dystrophy.

Acta Neuropathol Commun 2016 04 27;4(1):44. Epub 2016 Apr 27.

Institute of Neuropathology, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1186/s40478-016-0314-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847350PMC
April 2016

Immature teratoma of the tectum mesencephali with histopathological detection of rudimentary eye anlage in a 3-year-old boy: Report of a rare case.

Neuropathology 2016 Dec 25;36(6):556-560. Epub 2016 Apr 25.

Department of Neurosurgery, University Hospital, Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.1111/neup.12306DOI Listing
December 2016

C5b-9 deposits on endomysial capillaries in non-dermatomyositis cases.

Neuromuscul Disord 2016 Apr-May;26(4-5):283-91. Epub 2016 Mar 3.

Edinger Institute, Institute of Neurology, University of Frankfurt am Main, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nmd.2016.02.014DOI Listing
January 2017

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups.

Neuro Oncol 2016 06 28;18(6):790-6. Epub 2016 Jan 28.

Institute of Neuropathology, University Hospital Münster, Münster, Germany (C.T., V.R., A.J., W.P., M.H.); Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany (M.S.); Core Facility Genomics of the Medical Faculty Münster, Münster, Germany (A.W.); Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (S.H., U.K.); Department of Neuropathology, Institute for Pathology and Neuropathology, University of Tübingen, Tübingen, Germany (R.B.); Faculty of Medicine, Institute of Neuropathology, University of Duisburg-Essen, Essen, Germany (K.K.); Department of Neuropathology, Klinikum Bremen-Mitte, Bremen, Germany (M.B.); Institute of Neurology (Edinger Institute), Goethe University, Frankfurt, Germany (M.M.); Institute of Neuropathology, University of Bonn Medical Center, Bonn, Germany (T.P.); Department of Neuropathology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany (J.F.); Department of Neuropathology, Institute of Pathology, University of Würzburg, and Comprehensive Cancer Center Mainfranken (CCCM), Würzburg, Germany (C.M.M.); Department of Neuropathology, Sainte-Anne Hospital, Paris, France (P.V.); 2nd Department of Paediatrics, Semmelweis University, Budapest, Hungary (P.H.); Department of Hematopathology, Molecular Diagnostic Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (A.O.); Children's Brain Tumour Research Centre, School of Medicine, Queen's Medical Centre, University of Nottingham, Nottingham, UK (R.G.G.); Department of Pediatric Hematology Oncology and Blood and Marrow Transplantation, Cleveland Clinic Children's Hospital, Cleveland, Ohio (J.E.W.); Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany (A.K., A.v.D., D.C.); Clinical Cooperation Unit Neuropathology, German Research Center (DKFZ), Heidelberg, Germany (A.K., A.v.D., D.C.); German Cancer Consortium (DKTK), German Cancer Research Ce

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http://dx.doi.org/10.1093/neuonc/nov322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864264PMC
June 2016

Autophagy-associated proteins BAG3 and p62 in testicular cancer.

Oncol Rep 2016 Mar 22;35(3):1629-35. Epub 2015 Dec 22.

Department of Urology, Goethe University Frankfurt/Main, Germany.

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http://dx.doi.org/10.3892/or.2015.4505DOI Listing
March 2016

Comparative transcriptomics reveals similarities and differences between astrocytoma grades.

BMC Cancer 2015 Dec 16;15:952. Epub 2015 Dec 16.

Institute for Clinical Genetics, Faculty of Medicine Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1186/s12885-015-1939-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682229PMC
December 2015

ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma.

J Natl Cancer Inst 2016 May 6;108(5). Epub 2015 Dec 6.

Affiliations of authors:Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main , Germany (CZ, SG, KS, WSW); German Cancer Consortium (DKTK), partner site Frankfurt/Mainz , Germany (CZ, MCB, JPS, WSW); German Cancer Research Center (DKFZ), Heidelberg , Germany (CZ, MCB); Institute for Neurooncology (MCB, JPS), Edinger Institute (LJ, PZ, PNH, MM), Department of Neurology (PZ), and Institute of Neuroradiology (EH), Goethe University, Frankfurt am Main , Germany ; Institute for Transfusion Medicine, German Red Cross Blood Donation Service North-East and Medical Faculty Carl Gustav Carus, TU Dresden , Dresden , Germany (TT).

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http://dx.doi.org/10.1093/jnci/djv375DOI Listing
May 2016

Differential expression of vascular endothelial growth factor A, its receptors VEGFR-1, -2, and -3 and co-receptors neuropilin-1 and -2 does not predict bevacizumab response in human astrocytomas.

Neuro Oncol 2016 Feb 30;18(2):173-83. Epub 2015 Nov 30.

Institute of Neurology (Edinger Institute), Goethe University, Frankfurt, Germany (P.B., A.-E.B., M.D., P.Z., K.H., L.M., K.H.P., P.N.H., M.Mi.); Department of Neurosurgery, Goethe University, Frankfurt, Germany (K.F., V.S.); Dr. Senckenberg Institute of Neurooncology, University of Frankfurt am Main, Frankfurt am Main, Germany (K.F., O.B., J.P.S.); Department of Neuroradiology, University of Frankfurt am Main, Frankfurt am Main, Germany (E.H.); Department of Neurosurgery, University Hospital, Freiburg, Germany (M.Ma.); Cancer Consortium (DKTK), Heidelberg, Germany (O.B., J.P.S., K.H.P, P.N.H., M.Mi.); German Cancer Research Center (DKFZ), Heidelberg, Germany (O.B., J.P.S., K.H.P., P.N.H., M.Mi.); Department of Pathology, University of Heidelberg, Heidelberg, Germany (B.G.).

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http://dx.doi.org/10.1093/neuonc/nov288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724185PMC
February 2016

Prospective evaluation of serum glial fibrillary acidic protein (GFAP) as a diagnostic marker for glioblastoma.

J Neurooncol 2016 Jan 30;126(2):361-9. Epub 2015 Oct 30.

Department of Neurology, Goethe-University, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s11060-015-1978-8DOI Listing
January 2016

Genetic Alterations in Gliosarcoma and Giant Cell Glioblastoma.

Brain Pathol 2016 07 16;26(4):517-22. Epub 2015 Dec 16.

Section of Molecular Pathology, International Agency for Research on Cancer, F-69372, Lyon, France.

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http://dx.doi.org/10.1111/bpa.12328DOI Listing
July 2016

IκBζ, an atypical member of the inhibitor of nuclear factor kappa B family, is induced by γ-irradiation in glioma cells, regulating cytokine secretion and associated with poor prognosis.

Int J Oncol 2015 Nov 14;47(5):1971-80. Epub 2015 Sep 14.

Hertie Institute for Clinical Brain Research and Center Neurology, Molecular Neurology, Karl Eberhards University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.3892/ijo.2015.3159DOI Listing
November 2015

Alterations in the NF2/LATS1/LATS2/YAP Pathway in Schwannomas.

J Neuropathol Exp Neurol 2015 Oct;74(10):952-9

From the International Agency for Research on Cancer, Lyon, France (JEO, TO, KS, MF, GD, JM, FCK, HO); Institute of Neurology (Edinger Institute), Goethe-University Frankfurt, Frankfurt/Main, Germany (MM); and Department of Neurosurgery (BB) and Institute of Neuropathology (WP), University Hospital Munster, Munster, Germany.

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http://pdfs.journals.lww.com/jneuropath/2015/10000/Alteratio
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http://jnen.oxfordjournals.org/lookup/doi/10.1097/NEN.000000
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http://dx.doi.org/10.1097/NEN.0000000000000238DOI Listing
October 2015

Expression Profile of Sonic Hedgehog Pathway Members in the Developing Human Fetal Brain.

Biomed Res Int 2015 21;2015:494269. Epub 2015 Jul 21.

Edinger Institute, Institute of Neurology, Goethe University Frankfurt, 60528 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1155/2015/494269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523658PMC
May 2016

Comprehensive diagnostics in a case of hereditary diffuse leukodystrophy with spheroids.

BMC Neurol 2015 Jul 4;15:103. Epub 2015 Jul 4.

Dr. Senckenberg Institute of Neurooncology, University Hospital Frankfurt, Goethe University, Schleusenweg 2-16, 60528, Frankfurt, Germany.

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http://dx.doi.org/10.1186/s12883-015-0368-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491230PMC
July 2015

Towards an unbiased, collaborative effort to reach evidence about the presence of human cytomegalovirus in glioblastoma (and other tumors).

Neuro Oncol 2015 Jul;17(7):1039

Centre for Molecular Processing and School of Biosciences, University of Kent, Canterbury, United Kingdom (M.M.); Neurological Institute (Edinger Institute), Goethe University, Frankfurt am Main, Germany (M.M.); Institute of Medical Virology, Goethe University, Frankfurt am Main, Germany (J.C.).

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http://dx.doi.org/10.1093/neuonc/nov048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762008PMC
July 2015

Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors.

PLoS One 2015 19;10(5):e0127123. Epub 2015 May 19.

German Cancer Consortium (DKTK), Heidelberg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany; Senckenberg Institute of Neurooncology, University of Frankfurt am Main, Frankfurt am Main, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127123PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437987PMC
April 2016

Combination of Intraoperative Magnetic Resonance Imaging and Intraoperative Fluorescence to Enhance the Resection of Contrast Enhancing Gliomas.

Neurosurgery 2015 Jul;77(1):16-22; discussion 22

*Department of Neurosurgery, Goethe-University, Frankfurt, Germany; ‡Institute of Neurology (Edinger-Institute), Goethe-University, Frankfurt, Germany; §Institute of Neuroradiology, Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.1227/NEU.0000000000000729DOI Listing
July 2015

Melanoma brain metastasis is independent of lactate dehydrogenase A expression.

Neuro Oncol 2015 Oct 19;17(10):1374-85. Epub 2015 Mar 19.

Department of Biomedicine, University of Bergen, Bergen, Norway (T.S., H.E., K.O.S., S.H., E.H., C.B.R., R.Bj., F.T.); Department of Clinical Medicine, University of Bergen, Bergen, Norway (T.S., M.L.-J.); Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway (T.S., M.L.-J.); Edinger-Institute (Neurological Institute), Goethe-University Medical School, Frankfurt am Main, Germany (P.N.H., M.M.); Center for Nuclear Medicine/PET, Department of Oncology and Medical Physics, Haukeland University Hospital, Bergen, Norway (K.E.F.); Department of Dermatology, University Medical Center, Tübingen, Germany (B.W.); Department of Immunology, University of Tübingen, Tübingen, Germany (B.W.); Department of Neuropathology, Institute for Pathology and Neuropathology, University of Tübingen, Tübingen, Germany (R.Be.); Department of Diagnostic and Interventional Neuroradiology, University of Tübingen, Tübingen, Germany (B.B.); NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg (R.Bj.).

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http://dx.doi.org/10.1093/neuonc/nov040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578581PMC
October 2015

Intramedullary Solitary Fibrous Tumor--A Benign Form of Hemangiopericytoma? Case Report and Review of the Literature.

World Neurosurg 2015 Jul 6;84(1):189.e7-189.e12. Epub 2015 Mar 6.

Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1016/j.wneu.2015.02.036DOI Listing
July 2015

Multifactorial modulation of susceptibility to l-lysine in an animal model of glutaric aciduria type I.

Biochim Biophys Acta 2015 May 2;1852(5):768-77. Epub 2015 Jan 2.

Department of General Pediatrics, Division of Inherited Metabolic Diseases, University Children's Hospital Heidelberg, D-69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2014.12.022DOI Listing
May 2015