Publications by authors named "Michel Georges"

100Publications

The Polygenic and Monogenic Basis of Blood Traits and Diseases.

Authors:
Dragana Vuckovic Erik L Bao Parsa Akbari Caleb A Lareau Abdou Mousas Tao Jiang Ming-Huei Chen Laura M Raffield Manuel Tardaguila Jennifer E Huffman Scott C Ritchie Karyn Megy Hannes Ponstingl Christopher J Penkett Patrick K Albers Emilie M Wigdor Saori Sakaue Arden Moscati Regina Manansala Ken Sin Lo Huijun Qian Masato Akiyama Traci M Bartz Yoav Ben-Shlomo Andrew Beswick Jette Bork-Jensen Erwin P Bottinger Jennifer A Brody Frank J A van Rooij Kumaraswamy N Chitrala Peter W F Wilson Hélène Choquet John Danesh Emanuele Di Angelantonio Niki Dimou Jingzhong Ding Paul Elliott Tõnu Esko Michele K Evans Stephan B Felix James S Floyd Linda Broer Niels Grarup Michael H Guo Qi Guo Andreas Greinacher Jeff Haessler Torben Hansen Joanna M M Howson Wei Huang Eric Jorgenson Tim Kacprowski Mika Kähönen Yoichiro Kamatani Masahiro Kanai Savita Karthikeyan Fotios Koskeridis Leslie A Lange Terho Lehtimäki Allan Linneberg Yongmei Liu Leo-Pekka Lyytikäinen Ani Manichaikul Koichi Matsuda Karen L Mohlke Nina Mononen Yoshinori Murakami Girish N Nadkarni Kjell Nikus Nathan Pankratz Oluf Pedersen Michael Preuss Bruce M Psaty Olli T Raitakari Stephen S Rich Benjamin A T Rodriguez Jonathan D Rosen Jerome I Rotter Petra Schubert Cassandra N Spracklen Praveen Surendran Hua Tang Jean-Claude Tardif Mohsen Ghanbari Uwe Völker Henry Völzke Nicholas A Watkins Stefan Weiss Na Cai Kousik Kundu Stephen B Watt Klaudia Walter Alan B Zonderman Kelly Cho Yun Li Ruth J F Loos Julian C Knight Michel Georges Oliver Stegle Evangelos Evangelou Yukinori Okada David J Roberts Michael Inouye Andrew D Johnson Paul L Auer William J Astle Alexander P Reiner Adam S Butterworth Willem H Ouwehand Guillaume Lettre Vijay G Sankaran Nicole Soranzo

Cell 2020 Sep;182(5):1214-1231.e11

Human Genetics, Wellcome Sanger Institute, Hinxton, CB10 1SA, UK; National Institute for Health Research Blood and Transplant Research Unit (NIHR BTRU) in Donor Health and Genomics, University of Cambridge, Cambridge, CB1 8RN, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK; Department of Haematology, University of Cambridge, Cambridge, CB2 0PT, UK. Electronic address:

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September 2020

Genetic architecture of individual variation in recombination rate on the X chromosome in cattle.

Heredity (Edinb) 2020 Nov 10;125(5):304-316. Epub 2020 Jul 10.

Unit of Animal Genomics, GIGA-R and Faculty of Veterinary Medicine, University of Liège, Liège, Belgium.

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November 2020

SNP-based quantitative deconvolution of biological mixtures: application to the detection of cows with subclinical mastitis by whole-genome sequencing of tank milk.

Genome Res 2020 Aug 26;30(8):1201-1207. Epub 2020 Jun 26.

Unit of Animal Genomics, GIGA Institute & Faculty of Veterinary Medicine, University of Liège, 4000 Liège, Belgium.

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August 2020

Public health burden of pre-diabetes and diabetes in Luxembourg: finding from the 2013-2015 European Health Examination Survey.

BMJ Open 2019 01 21;9(1):e022206. Epub 2019 Jan 21.

Epidemiology and Public Health Research Unit, Department of Population Health, Luxembourg Institute of Health, Strassen, Luxembourg.

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January 2019

Harnessing genomic information for livestock improvement.

Nat Rev Genet 2019 03;20(3):135-156

Queensland Alliance for Agriculture and Food Innovation (QAAFI), Queensland Bioscience Precinct, The University of Queensland, Brisbane, Queensland, Australia.

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March 2019

Study design and characteristics of the Luxembourg European Health Examination Survey (EHES-LUX).

BMC Public Health 2018 Oct 11;18(1):1169. Epub 2018 Oct 11.

Epidemiology and Public Health Research Unit, Department of Population Health, Luxembourg Institute of Health, Strassen, Luxembourg.

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October 2018

Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 09;50(9):1343

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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September 2018

Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.

Nat Genet 2018 08 16;50(8):1072-1080. Epub 2018 Jul 16.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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August 2018

CCDC88B is required for pathogenesis of inflammatory bowel disease.

Nat Commun 2017 10 13;8(1):932. Epub 2017 Oct 13.

McGill Center for the Study of Complex Traits, Department of Human Genetics, Department of Biochemistry, McGill University, 3649 Sir William Osler Promenade, Montreal, QC, Canada, H3G 0B1.

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October 2017

Genome-Wide Copy Number Variation Scan Identifies Complement Component C4 as Novel Susceptibility Gene for Crohn's Disease.

Inflamm Bowel Dis 2016 Mar;22(3):505-15

*Department of Clinical and Experimental Medicine, TARGID, KU Leuven, Leuven, Belgium; †Department of Electrical Engineering (ESAT), STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, KU Leuven, Leuven, Belgium; ‡iMinds Department of Medical Information Technologies, KU Leuven, Leuven, Belgium; §Department of Human Genetics, KU Leuven, Leuven, Belgium; ‖Department of Gastroenterology, Ghent University Hospital, Gent, Belgium; ¶Erasmus Hospital, Free University of Brussels, Department of Gastroenterology, Brussels, Belgium; **Unit of Animal Genomics, Groupe Interdisciplinaire de Genoproteomique Appliquee (GIGA-R) and Faculty of Veterinary Medicine, University of Liege, Liege, Belgium; ††Division of Gastroenterology, Centre Hospitalier Universitaire, Université de Liege, Liège, Belgium; ‡‡Division of Gastroenterology, UZ Leuven, Leuven, Belgium; and §§Department of Electrical Engineering and Computer Science, Bioinformatics-Statistical Genetics, Montefiore Institute, Universty of Liège, Liège, Belgium.

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March 2016

Reverse genetic screen for loss-of-function mutations uncovers a frameshifting deletion in the melanophilin gene accountable for a distinctive coat color in Belgian Blue cattle.

Anim Genet 2016 Feb 19;47(1):110-3. Epub 2015 Nov 19.

GIGA-R and Faculty of Veterinary Medicine, University of Liège, 1 avenue de l'hôpital, 4000 Liège, Belgium.

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February 2016

Ectopic Expression of Retrotransposon-Derived PEG11/RTL1 Contributes to the Callipyge Muscular Hypertrophy.

PLoS One 2015 16;10(10):e0140594. Epub 2015 Oct 16.

Unit of Animal Genomics, GIGA Research Center and Faculty of Veterinary Medicine, University of Liège, 1 Avenue de l'Hôpital, Liège, Belgium.

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June 2016

A stop-gain in the laminin, alpha 3 gene causes recessive junctional epidermolysis bullosa in Belgian Blue cattle.

Anim Genet 2015 Oct 15;46(5):566-70. Epub 2015 Sep 15.

Unit of Animal Genomics, GIGA-R and Faculty of Veterinary Medicine, University of Liège, Liège, Belgium.

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October 2015

On the use of the transmission disequilibrium test to detect pseudo-autosomal variants affecting traits with sex-limited expression.

Anim Genet 2015 Aug 21;46(4):395-402. Epub 2015 May 21.

Unit of Animal Genomics, GIGA-R & Faculty of Veterinary Medicine, University of Liège, Bd de Colonster B43, 4000, Liège, Belgium.

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August 2015

LINKPHASE3: an improved pedigree-based phasing algorithm robust to genotyping and map errors.

Bioinformatics 2015 May 7;31(10):1677-9. Epub 2015 Jan 7.

Unit of Animal Genomics, GIGA-R, University of Liège (B34), 1 avenue de l'Hôpital, B-4000, Liège, Belgium.

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May 2015

Experimental evaluation does not reveal a direct effect of microRNA from the callipyge locus on DLK1 expression.

BMC Genomics 2014 Oct 30;15:944. Epub 2014 Oct 30.

Unit of Animal Genomics, GIGA-R & Faculty of Veterinary Medicine, University of Liège (B34), 1 Avenue de l'Hôpital, 4000 Liège, Belgium.

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October 2014

Selection in action: dissecting the molecular underpinnings of the increasing muscle mass of Belgian Blue Cattle.

BMC Genomics 2014 Sep 17;15:796. Epub 2014 Sep 17.

Unit of Animal Genomics, GIGA-R & Faculty of Veterinary Medicine, University of Liège - B34 (+1), Avenue de l'Hôpital 1, Liège B-4000, Belgium.

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September 2014

Towards sequence-based genomic selection of cattle.

Authors:
Michel Georges

Nat Genet 2014 Aug;46(8):807-9

Unit of Animal Genomics, Groupe Interdisciplinaire de Génoprotéomique Appliquée-Research (GIGA-R) and Faculty of Veterinary Medicine, University of Liège, Liège, Belgium.

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August 2014

A genome scan conducted in a multigenerational pedigree with convergent strabismus supports a complex genetic determinism.

PLoS One 2013 23;8(12):e83574. Epub 2013 Dec 23.

Unit of Animal Genomics, GIGA-R & Faculty of Veterinary Medicine, University of Liège (B34), Liège, Belgium.

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March 2015

Deep sequencing reveals abundant noncanonical retroviral microRNAs in B-cell leukemia/lymphoma.

Proc Natl Acad Sci U S A 2013 Feb 23;110(6):2306-11. Epub 2013 Jan 23.

Unit of Animal Genomics, Groupe Interdisciplinaire Génoprotéomique Appliquée, Université de Liège, 4000 Liège, Belgium.

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February 2013

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors:
Luke Jostins Stephan Ripke Rinse K Weersma Richard H Duerr Dermot P McGovern Ken Y Hui James C Lee L Philip Schumm Yashoda Sharma Carl A Anderson Jonah Essers Mitja Mitrovic Kaida Ning Isabelle Cleynen Emilie Theatre Sarah L Spain Soumya Raychaudhuri Philippe Goyette Zhi Wei Clara Abraham Jean-Paul Achkar Tariq Ahmad Leila Amininejad Ashwin N Ananthakrishnan Vibeke Andersen Jane M Andrews Leonard Baidoo Tobias Balschun Peter A Bampton Alain Bitton Gabrielle Boucher Stephan Brand Carsten Büning Ariella Cohain Sven Cichon Mauro D'Amato Dirk De Jong Kathy L Devaney Marla Dubinsky Cathryn Edwards David Ellinghaus Lynnette R Ferguson Denis Franchimont Karin Fransen Richard Gearry Michel Georges Christian Gieger Jürgen Glas Talin Haritunians Ailsa Hart Chris Hawkey Matija Hedl Xinli Hu Tom H Karlsen Limas Kupcinskas Subra Kugathasan Anna Latiano Debby Laukens Ian C Lawrance Charlie W Lees Edouard Louis Gillian Mahy John Mansfield Angharad R Morgan Craig Mowat William Newman Orazio Palmieri Cyriel Y Ponsioen Uros Potocnik Natalie J Prescott Miguel Regueiro Jerome I Rotter Richard K Russell Jeremy D Sanderson Miquel Sans Jack Satsangi Stefan Schreiber Lisa A Simms Jurgita Sventoraityte Stephan R Targan Kent D Taylor Mark Tremelling Hein W Verspaget Martine De Vos Cisca Wijmenga David C Wilson Juliane Winkelmann Ramnik J Xavier Sebastian Zeissig Bin Zhang Clarence K Zhang Hongyu Zhao Mark S Silverberg Vito Annese Hakon Hakonarson Steven R Brant Graham Radford-Smith Christopher G Mathew John D Rioux Eric E Schadt Mark J Daly Andre Franke Miles Parkes Severine Vermeire Jeffrey C Barrett Judy H Cho

Nature 2012 Nov;491(7422):119-24

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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November 2012

Genetic variants in REC8, RNF212, and PRDM9 influence male recombination in cattle.

PLoS Genet 2012 26;8(7):e1002854. Epub 2012 Jul 26.

Unit of Animal Genomics, GIGA-R and Faculty of Veterinary Medicine, University of Liège, Liège, Belgium.

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January 2013

A splice site variant in the bovine RNF11 gene compromises growth and regulation of the inflammatory response.

PLoS Genet 2012 15;8(3):e1002581. Epub 2012 Mar 15.

Unit of Animal Genomics, GIGA-R, Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium.

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September 2012

LUPA: a European initiative taking advantage of the canine genome architecture for unravelling complex disorders in both human and dogs.

Vet J 2011 Aug 12;189(2):155-9. Epub 2011 Jul 12.

Unit of Animal Genomics, GIGA-R and Faculty of Veterinary Medicine, University of Liège, Avenue de l'Hôpital 1, 4000 Liège, Belgium.

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August 2011

Results of a haplotype-based GWAS for recurrent laryngeal neuropathy in the horse.

Mamm Genome 2011 Oct 23;22(9-10):613-20. Epub 2011 Jun 23.

Unit of Animal Genetics, GIGA-Research, Faculty of Veterinary Medicine, University of Liège, 1 avenue de l'hôpital, B-4000 Liège, Belgium.

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October 2011

Variants modulating the expression of a chromosome domain encompassing PLAG1 influence bovine stature.

Nat Genet 2011 May 24;43(5):405-13. Epub 2011 Apr 24.

Unit of Animal Genomics, Interdisciplinary Institute of Applied Genomics (GIGA-R) and Faculty of Veterinary Medicine, University of Liège (B34), Liège, Belgium.

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May 2011

Improved risk prediction for Crohn's disease with a multi-locus approach.

Hum Mol Genet 2011 Jun 22;20(12):2435-42. Epub 2011 Mar 22.

Department of Epidemiology and Public Health, Yale University, New Haven, CT 06520, USA.

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June 2011

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Authors:
Carl A Anderson Gabrielle Boucher Charlie W Lees Andre Franke Mauro D'Amato Kent D Taylor James C Lee Philippe Goyette Marcin Imielinski Anna Latiano Caroline Lagacé Regan Scott Leila Amininejad Suzannah Bumpstead Leonard Baidoo Robert N Baldassano Murray Barclay Theodore M Bayless Stephan Brand Carsten Büning Jean-Frédéric Colombel Lee A Denson Martine De Vos Marla Dubinsky Cathryn Edwards David Ellinghaus Rudolf S N Fehrmann James A B Floyd Timothy Florin Denis Franchimont Lude Franke Michel Georges Jürgen Glas Nicole L Glazer Stephen L Guthery Talin Haritunians Nicholas K Hayward Jean-Pierre Hugot Gilles Jobin Debby Laukens Ian Lawrance Marc Lémann Arie Levine Cecile Libioulle Edouard Louis Dermot P McGovern Monica Milla Grant W Montgomery Katherine I Morley Craig Mowat Aylwin Ng William Newman Roel A Ophoff Laura Papi Orazio Palmieri Laurent Peyrin-Biroulet Julián Panés Anne Phillips Natalie J Prescott Deborah D Proctor Rebecca Roberts Richard Russell Paul Rutgeerts Jeremy Sanderson Miquel Sans Philip Schumm Frank Seibold Yashoda Sharma Lisa A Simms Mark Seielstad A Hillary Steinhart Stephan R Targan Leonard H van den Berg Morten Vatn Hein Verspaget Thomas Walters Cisca Wijmenga David C Wilson Harm-Jan Westra Ramnik J Xavier Zhen Z Zhao Cyriel Y Ponsioen Vibeke Andersen Leif Torkvist Maria Gazouli Nicholas P Anagnou Tom H Karlsen Limas Kupcinskas Jurgita Sventoraityte John C Mansfield Subra Kugathasan Mark S Silverberg Jonas Halfvarson Jerome I Rotter Christopher G Mathew Anne M Griffiths Richard Gearry Tariq Ahmad Steven R Brant Mathias Chamaillard Jack Satsangi Judy H Cho Stefan Schreiber Mark J Daly Jeffrey C Barrett Miles Parkes Vito Annese Hakon Hakonarson Graham Radford-Smith Richard H Duerr Séverine Vermeire Rinse K Weersma John D Rioux

Nat Genet 2011 Mar 6;43(3):246-52. Epub 2011 Feb 6.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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March 2011

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

Nat Genet 2010 Dec;42(12):1118-25

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany.

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December 2010

Assessing the effect of the CLPG mutation on the microRNA catalog of skeletal muscle using high-throughput sequencing.

Genome Res 2010 Dec 13;20(12):1651-62. Epub 2010 Oct 13.

Department of Animal Production, GIGA-R, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium.

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December 2010

Demonstrating polymorphic miRNA-mediated gene regulation in vivo: application to the g+6223G->A mutation of Texel sheep.

RNA 2010 Sep 2;16(9):1854-63. Epub 2010 Aug 2.

Unit of Animal Genomics, GIGA Research Center, Faculty of Veterinary Medicine, University of Liège, 4000-Liège, Belgium.

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September 2010

A hidden markov model combining linkage and linkage disequilibrium information for haplotype reconstruction and quantitative trait locus fine mapping.

Genetics 2010 Mar 14;184(3):789-98. Epub 2009 Dec 14.

Unit of Animal Genomics, GIGA-Research and Department of Animal Production, Faculty of Veterinary Medicine, University of Liège, Belgium.

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March 2010

Centralized Pan-European survey on the under-treatment of hypercholesterolaemia (CEPHEUS): overall findings from eight countries.

Curr Med Res Opin 2010 Feb;26(2):445-54

Endocrinology and Nutrition Department, Université Catholique de Louvain, Avenue Hippocrate 54, B-1200 Woluwe-Saint-Lambert, Brussels, Belgium.

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February 2010

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Authors:
Marcin Imielinski Robert N Baldassano Anne Griffiths Richard K Russell Vito Annese Marla Dubinsky Subra Kugathasan Jonathan P Bradfield Thomas D Walters Patrick Sleiman Cecilia E Kim Aleixo Muise Kai Wang Joseph T Glessner Shehzad Saeed Haitao Zhang Edward C Frackelton Cuiping Hou James H Flory George Otieno Rosetta M Chiavacci Robert Grundmeier Massimo Castro Anna Latiano Bruno Dallapiccola Joanne Stempak Debra J Abrams Kent Taylor Dermot McGovern Gary Silber Iwona Wrobel Antonio Quiros Jeffrey C Barrett Sarah Hansoul Dan L Nicolae Judy H Cho Richard H Duerr John D Rioux Steven R Brant Mark S Silverberg Kent D Taylor M Michael Barmuda Alain Bitton Themistocles Dassopoulos Lisa Wu Datta Todd Green Anne M Griffiths Emily O Kistner Michael T Murtha Miguel D Regueiro Jerome I Rotter L Philip Schumm A Hillary Steinhart Stephen R Targan Ramnik J Xavier Cécile Libioulle Cynthia Sandor Mark Lathrop Jacques Belaiche Olivier Dewit Ivo Gut Simon Heath Debby Laukens Myriam Mni Paul Rutgeerts André Van Gossum Diana Zelenika Denis Franchimont J P Hugot Martine de Vos Severine Vermeire Edouard Louis Lon R Cardon Carl A Anderson Hazel Drummond Elaine Nimmo Tariq Ahmad Natalie J Prescott Clive M Onnie Sheila A Fisher Jonathan Marchini Jilur Ghori Suzannah Bumpstead Rhian Gwillam Mark Tremelling Panos Delukas John Mansfield Derek Jewell Jack Satsangi Christopher G Mathew Miles Parkes Michel Georges Mark J Daly Melvin B Heyman George D Ferry Barbara Kirschner Jessica Lee Jonah Essers Richard Grand Michael Stephens Arie Levine David Piccoli John Van Limbergen Salvatore Cucchiara Dimitri S Monos Stephen L Guthery Lee Denson David C Wilson Straun F A Grant Mark Daly Mark S Silverberg Jack Satsangi Hakon Hakonarson

Nat Genet 2009 Dec 15;41(12):1335-40. Epub 2009 Nov 15.

Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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December 2009

Patrocles: a database of polymorphic miRNA-mediated gene regulation in vertebrates.

Nucleic Acids Res 2010 Jan 11;38(Database issue):D640-51. Epub 2009 Nov 11.

Unit of Animal Genomics, GIGA-RSystems and Modeling, Montefiore Institute, University of Liège, Belgium.

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January 2010

A nonsense mutation in cGMP-dependent type II protein kinase (PRKG2) causes dwarfism in American Angus cattle.

Proc Natl Acad Sci U S A 2009 Nov 3;106(46):19250-5. Epub 2009 Nov 3.

Department of Animal Science, Iowa State University, 2255 Kildee Hall, Ames, IA 50011-3150, USA.

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November 2009

Balancing selection of a frame-shift mutation in the MRC2 gene accounts for the outbreak of the Crooked Tail Syndrome in Belgian Blue Cattle.

PLoS Genet 2009 Sep 25;5(9):e1000666. Epub 2009 Sep 25.

Unit of Animal Genomics, GIGA-R, Department of Animal Sciences, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium.

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September 2009

Genetics of ulcerative colitis: the come-back of interleukin 10.

Gut 2009 Sep;58(9):1173-6

Department of Gastroenterology, CHU of Liège, Liège, Belgium.

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September 2009

Mapping QTL influencing gastrointestinal nematode burden in Dutch Holstein-Friesian dairy cattle.

BMC Genomics 2009 Mar 2;10:96. Epub 2009 Mar 2.

Unit of Animal Genomics, Faculty of Veterinary Medicine and Centre for Biomedical Integrative Genoproteomics, University of Liège (B43), Liège, Belgium.

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March 2009

Coinfection with two closely related alphaherpesviruses results in a highly diversified recombination mosaic displaying negative genetic interference.

J Virol 2009 Apr 19;83(7):3127-37. Epub 2009 Jan 19.

Department of Infectious and Parasitic Diseases, Virology and Immunology, Faculty of Veterinary Medicine, University of Liège, B-4000 Liège, Belgium.

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April 2009

Characterization of the bovine pseudoautosomal boundary: Documenting the evolutionary history of mammalian sex chromosomes.

Genome Res 2008 Dec 3;18(12):1884-95. Epub 2008 Nov 3.

Unit of Animal Genomics, GIGA-R and Faculty of Veterinary Medicine, University of Liège, Belgium.

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December 2008

On the detection of imprinted quantitative trait loci in line crosses: effect of linkage disequilibrium.

Genetics 2008 Oct 9;180(2):1167-75. Epub 2008 Sep 9.

Faculty of Veterinary Medicine, University of Liège, 4000-Liège, Belgium.

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October 2008

Mapping, fine mapping, and molecular dissection of quantitative trait Loci in domestic animals.

Authors:
Michel Georges

Annu Rev Genomics Hum Genet 2007 ;8:131-62

Unit of Animal Genomics, GIGA-R and Faculty of Veterinary Medicine, University of Liège, 4000-Liège, Belgium.

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December 2007

Polymorphic miRNA-mediated gene regulation: contribution to phenotypic variation and disease.

Curr Opin Genet Dev 2007 Jun 30;17(3):166-76. Epub 2007 Apr 30.

Unit of Animal Genomics, GIGA-R and Faculty of Veterinary Medicine, University of Liège, (B34), 1 Avenue de l'Hôpital, 4000-Liège, Belgium.

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June 2007

Genetical metabolomics of flavonoid biosynthesis in Populus: a case study.

Plant J 2006 Jul 15;47(2):224-37. Epub 2006 Jun 15.

Department of Plant Systems Biology, Flanders Interuniversity Institute for Biotechnology (VIB), Ghent University, B-9052 Gent, Belgium.

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July 2006

A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep.

Nat Genet 2006 Jul 4;38(7):813-8. Epub 2006 Jun 4.

Unit of Animal Genomics, Department of Animal Production, Faculty of Veterinary Medicine & Centre for Biomedical Integrative Genoproteomics, University of Liège (B43), 20 Boulevard de Colonster, 4000 Liège, Belgium.

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July 2006

The callipyge mutation enhances bidirectional long-range DLK1-GTL2 intergenic transcription in cis.

Proc Natl Acad Sci U S A 2006 May 11;103(21):8119-24. Epub 2006 May 11.

Unit of Animal Genetics, Faculty of Veterinary Medicine and Centre of Biomedical Integrative Genoproteomics (CBIG), University of Liège (B43), 20 Boulevard de Colonster, 4000-Liège, Belgium.

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May 2006

Linkage disequilibrium on the bovine X chromosome: characterization and use in quantitative trait locus mapping.

Genetics 2006 Jul 30;173(3):1777-86. Epub 2006 Apr 30.

Unit of Animal Genomics, Department of Animal Producion, University of Liège, Belgium.

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July 2006

Genetic identification of distinct loci controlling mammary tumor multiplicity, latency, and aggressiveness in the rat.

Mamm Genome 2006 Apr 4;17(4):310-21. Epub 2006 Apr 4.

Université Libre de Bruxelles, Institut de Biologie et de Médecine Moléculaires, Rue Profs Jeener & Brachet, 12, Gosselies, B-6041, Belgium.

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April 2006

BEGAIN: a novel imprinted gene that generates paternally expressed transcripts in a tissue- and promoter-specific manner in sheep.

Mamm Genome 2005 Oct 29;16(10):801-14. Epub 2005 Oct 29.

Department of Animal, Dairy, and Veterinary Sciences, Utah State University, 4700 Old Main Hill, Logan, Utah 84322-4700, USA.

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October 2005

Transgenic engineering of male-specific muscular hypertrophy.

Proc Natl Acad Sci U S A 2005 May 25;102(18):6413-8. Epub 2005 Apr 25.

Unit of Factorial and Molecular Genetics, Department of Animal Production, University of Liège (B43), 20 Boulevard de Colonster, B-4000 Liège, Belgium.

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May 2005

The callipyge mutation and other genes that affect muscle hypertrophy in sheep.

Genet Sel Evol 2005 ;37 Suppl 1:S65-81

Department of Animal, Dairy and Veterinary Sciences, Utah State University, Logan, UT 84322, USA.

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March 2005

Ectopic expression of DLK1 protein in skeletal muscle of padumnal heterozygotes causes the callipyge phenotype.

Curr Biol 2004 Oct;14(20):1858-62

Department of Genetics, Faculty of Veterinary Medicine, University of Liège, B 43 Sart Tilman, Boulevard du Colonster 20, 4000-Liège, Belgium.

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October 2004

Toward improved guideline quality: using the COGS statement with GEM.

Stud Health Technol Inform 2004 ;107(Pt 1):159-63

Yale Center for Medical Informatics, Yale University School of Medicine, 300 George Street, New Haven, CT 06511, USA.

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June 2005

Genetic and functional confirmation of the causality of the DGAT1 K232A quantitative trait nucleotide in affecting milk yield and composition.

Proc Natl Acad Sci U S A 2004 Feb;101(8):2398-403

Department of Genetics, Faculty of Veterinary Medicine, University of Liège (B43), 20 Boulevard de Colonster, 4000 Liège (Sart Tilman), Belgium.

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February 2004

Domestic-animal genomics: deciphering the genetics of complex traits.

Nat Rev Genet 2004 Mar;5(3):202-12

Department of Medical Biochemistry and Microbiology, Uppsala University, Box 597, SE-751 24 Uppsala, Sweden.

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March 2004

A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig.

Nature 2003 Oct;425(6960):832-6

Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala University, BMC, Box 597, SE-751 24 Uppsala, Sweden.

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October 2003

The callipyge locus: evidence for the trans interaction of reciprocally imprinted genes.

Trends Genet 2003 May;19(5):248-52

Department of Genetics, Faculty of Veterinary Medicine, University of Liège (B43), 20 Bd de Colonster, 4000-Liège, Belgium.

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May 2003

Haplotype diversity of the myostatin gene among beef cattle breeds.

Genet Sel Evol 2003 Jan-Feb;35(1):103-18

Laboratorio de genética molecular, Facultad de Veterinaria, Universidad Complutense de Madrid, 28040 Madrid, Spain.

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September 2003