Publications by authors named "Michel Aguet"

20Publications

TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex.

Authors:
Dario Zimmerli Costanza Borrelli Amaia Jauregi-Miguel Simon Söderholm Salome Brütsch Nikolaos Doumpas Jan Reichmuth Fabienne Murphy-Seiler MIchel Aguet Konrad Basler Andreas E Moor Claudio Cantù

Elife 2020 08 18;9. Epub 2020 Aug 18.

Wallenberg Centre for Molecular Medicine, Linköping University, Linköping, Sweden.

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August 2020

Mutations in and genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling.

Authors:
Claudio Cantù Anastasia Felker Dario Zimmerli Karin D Prummel Elena M Cabello Elena Chiavacci Kevin M Méndez-Acevedo Lucia Kirchgeorg Sibylle Burger Jorge Ripoll Tomas Valenta George Hausmann Nathalie Vilain Michel Aguet Alexa Burger Daniela Panáková Konrad Basler Christian Mosimann

Genes Dev 2018 11 26;32(21-22):1443-1458. Epub 2018 Oct 26.

Institute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.

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November 2018

Cancer Metastasis: A Reappraisal of Its Underlying Mechanisms and Their Relevance to Treatment.

Authors:
Nicolo Riggi Michel Aguet Ivan Stamenkovic

Annu Rev Pathol 2018 01 25;13:117-140. Epub 2017 Oct 25.

Experimental Pathology Service, Centre Hospitalier Universitaire Vaudois, University of Lausanne, CH-1005 Lausanne, Switzerland; email:

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January 2018

The Multi-kinase Inhibitor Debio 0617B Reduces Maintenance and Self-renewal of Primary Human AML CD34 Stem/Progenitor Cells.

Authors:
Maximilien Murone Ramin Radpour Antoine Attinger Anne Vaslin Chessex Anne-Laure Huguenin Christian M Schürch Yara Banz Saumitra Sengupta Michel Aguet Stefania Rigotti Yogeshwar Bachhav Frédéric Massière Murali Ramachandra Andres McAllister Carsten Riether

Mol Cancer Ther 2017 08 3;16(8):1497-1510. Epub 2017 May 3.

Tumor Immunology, Department of Clinical Research, University of Bern, Bern, Switzerland.

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August 2017

Debio 0617B Inhibits Growth of STAT3-Driven Solid Tumors through Combined Inhibition of JAK, SRC, and Class III/V Receptor Tyrosine Kinases.

Authors:
Maximilien Murone Anne Vaslin Chessex Antoine Attinger Raghuveer Ramachandra Shankar J Shetty Girish Daginakatte Saumitra Sengupta Sivapriya Marappan Samiulla Dhodheri Stefania Rigotti Yogeshwar Bachhav Silvano Brienza Peter Traxler Marc Lang Michel Aguet Vincent Zoete Olivier Michielin Courtney Nicholas Faye M Johnson Murali Ramachandra Andres McAllister

Mol Cancer Ther 2016 10 20;15(10):2334-2343. Epub 2016 Jul 20.

Debiopharm International S.A., Lausanne, Switzerland.

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October 2016

Wnt Ligands Secreted by Subepithelial Mesenchymal Cells Are Essential for the Survival of Intestinal Stem Cells and Gut Homeostasis.

Authors:
Tomas Valenta Bahar Degirmenci Andreas E Moor Patrick Herr Dario Zimmerli Matthias B Moor George Hausmann Claudio Cantù Michel Aguet Konrad Basler

Cell Rep 2016 05 21;15(5):911-918. Epub 2016 Apr 21.

Institute of Molecular Life Sciences, University of Zurich, Winterthurerstr. 190, 8057 Zurich, Switzerland. Electronic address:

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May 2016

The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma.

Authors:
Luisa Cironi Tanja Petricevic Victor Fernandes Vieira Paolo Provero Carlo Fusco Sandrine Cornaz Giulia Fregni Igor Letovanec Michel Aguet Ivan Stamenkovic

Sci Rep 2016 Feb 24;6:22113. Epub 2016 Feb 24.

Institute of Pathology University of Lausanne and CHUV Lausanne, Switzerland.

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February 2016

BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer.

Authors:
Andreas E Moor Pascale Anderle Claudio Cantù Patrick Rodriguez Norbert Wiedemann Frédérique Baruthio Jürgen Deka Sylvie André Tomas Valenta Matthias B Moor Balázs Győrffy David Barras Mauro Delorenzi Konrad Basler Michel Aguet

EBioMedicine 2015 Dec 30;2(12):1932-43. Epub 2015 Oct 30.

Swiss Institute for Experimental Cancer Research (ISREC), Ecole Polytechnique Fédérale de Lausanne (EPFL), School of Life Sciences, CH-1015 Lausanne, Switzerland.

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December 2015

Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development.

Authors:
Claudio Cantù Dario Zimmerli George Hausmann Tomas Valenta Andreas Moor Michel Aguet Konrad Basler

Genes Dev 2014 Sep;28(17):1879-84

Institute of Molecular Life Sciences, University of Zurich, 8057 Zurich, Switzerland;

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September 2014

The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription.

Authors:
Claudio Cantù Tomas Valenta George Hausmann Nathalie Vilain Michel Aguet Konrad Basler

Development 2013 Jun 1;140(11):2377-86. Epub 2013 May 1.

Institute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.

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June 2013

Defining new criteria for selection of cell-based intestinal models using publicly available databases.

Authors:
Jon Christensen Sara El-Gebali Manuela Natoli Thierry Sengstag Mauro Delorenzi Susanne Bentz Hanifa Bouzourene Martin Rumbo Armando Felsani Sanna Siissalo Jouni Hirvonen Maya R Vila Piercarlo Saletti Michel Aguet Pascale Anderle

BMC Genomics 2012 Jun 22;13:274. Epub 2012 Jun 22.

1Institute for Macromolecular Chemistry and Center for Biological Signaling Studies (BIOSS), University of Freiburg, Freiburg, Germany.

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June 2012

Probing transcription-specific outputs of β-catenin in vivo.

Authors:
Tomas Valenta Max Gay Sarah Steiner Kalina Draganova Martina Zemke Raymond Hoffmans Paolo Cinelli Michel Aguet Lukas Sommer Konrad Basler

Genes Dev 2011 Dec;25(24):2631-43

Institute of Molecular Life Sciences, University of Zurich, 8057 Zurich, Switzerland.

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December 2011

Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas.

Authors:
Jürgen Deka Norbert Wiedemann Pascale Anderle Fabienne Murphy-Seiler Jennyfer Bultinck Sven Eyckerman Jean-Christophe Stehle Sylvie André Nathalie Vilain Olav Zilian Sylvie Robine Mauro Delorenzi Konrad Basler Michel Aguet

Cancer Res 2010 Aug 3;70(16):6619-28. Epub 2010 Aug 3.

Swiss Institute for Experimental Cancer Research, Swiss National Center of Competence in Research Molecular Oncology, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

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August 2010

BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration.

Authors:
Andrew S Brack Fabienne Murphy-Seiler Jasmine Hanifi Jürgen Deka Sven Eyckerman Charles Keller Michel Aguet Thomas A Rando

Dev Biol 2009 Nov 21;335(1):93-105. Epub 2009 Aug 21.

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305-5235, USA.

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November 2009

A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer.

Authors:
Pierre Farmer Hervé Bonnefoi Pascale Anderle David Cameron Pratyaksha Wirapati Pratyakasha Wirapati Véronique Becette Sylvie André Martine Piccart Mario Campone Etienne Brain Gaëtan Macgrogan Thierry Petit Jacek Jassem Frédéric Bibeau Emmanuel Blot Jan Bogaerts Michel Aguet Jonas Bergh Richard Iggo Mauro Delorenzi

Nat Med 2009 Jan 4;15(1):68-74. Epub 2009 Jan 4.

Swiss National Centre of Competence in Research Molecular Oncology, Swiss Institute for Experimental Cancer Research, Ecole Polytechnique Fédérale de Lausanne, School of Life Sciences, Epalinges s/Lausanne, Switzerland.

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January 2009

Normal hemopoiesis and lymphopoiesis in the combined absence of numb and numblike.

Authors:
Anne Wilson Denis-Luc Ardiet Catherine Saner Nathalie Vilain Friedrich Beermann Michel Aguet H Robson Macdonald Olav Zilian

J Immunol 2007 Jun;178(11):6746-51

Ludwig Institute for Cancer Research, Lausanne Branch, University of Lausanne, Switzerland.

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June 2007

SOST expression is restricted to the great arteries during embryonic and neonatal cardiovascular development.

Authors:
Rutger L van Bezooijen Marco C Deruiter Nathalie Vilain Rui M Monteiro Annemieke Visser Lianne van der Wee-Pals Conny J van Munsteren Pancras C W Hogendoorn Michel Aguet Christine L Mummery Socrates E Papapoulos Peter Ten Dijke Clemens W G M Löwik

Dev Dyn 2007 Feb;236(2):606-12

Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Leiden, The Netherlands.

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February 2007

Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation.

Authors:
Xi-De Wang Ching Ching Leow Jiping Zha Zhijun Tang Zora Modrusan Freddy Radtke Michel Aguet Frederic J de Sauvage Wei-Qiang Gao

Dev Biol 2006 Feb 15;290(1):66-80. Epub 2005 Dec 15.

Department of Molecular Biology, Genentech, Inc., 1 DNA Way, South San Francisco, CA 94080, USA.

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February 2006

Notch1 control of oligodendrocyte differentiation in the spinal cord.

Authors:
Stephane Genoud Corinna Lappe-Siefke Sandra Goebbels Freddy Radtke Michel Aguet Steven S Scherer Ueli Suter Klaus-Armin Nave Ned Mantei

J Cell Biol 2002 Aug 19;158(4):709-18. Epub 2002 Aug 19.

Department of Biology, Institute of Cell Biology, Swiss Federal Institute of Technology, ETH-Hönggerberg, CH-8093 Zürich, Switzerland.

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August 2002

Notch1 is required for neuronal and glial differentiation in the cerebellum.

Authors:
Simone Lütolf Freddy Radtke Michel Aguet Ueli Suter Verdon Taylor

Development 2002 Jan;129(2):373-85

Institute of Cell Biology, Department of Biology, Swiss Federal Institute of Technology, CH-8093 Zurich, Switzerland.

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January 2002