Michal Lotem

Michal Lotem

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Michal Lotem

Michal Lotem

Publications by authors named "Michal Lotem"

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Predicting response to pembrolizumab in metastatic melanoma by a new personalization algorithm.

J Transl Med 2019 Oct 7;17(1):338. Epub 2019 Oct 7.

Optimata Ltd., Hate'ena St. 10, POB 282, 6099100, Bene-Ataroth, Israel.

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http://dx.doi.org/10.1186/s12967-019-2081-2DOI Listing
October 2019

Potent Activation of Human T Cells by mRNA Encoding Constitutively Active CD40.

J Immunol 2018 11 10;201(10):2959-2968. Epub 2018 Oct 10.

Laboratory of Immunology, MIGAL-Galilee Research Institute, Kiryat Shmona 11016, Israel;

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http://dx.doi.org/10.4049/jimmunol.1701725DOI Listing
November 2018

Neurologic complications of immune checkpoint inhibitors.

J Neurooncol 2018 May 13;137(3):601-609. Epub 2018 Jan 13.

Department of Neurology, Rabin Medical Center, Beilinson Hospital, 39 Jabotinski St., Petah Tikva, Israel.

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http://dx.doi.org/10.1007/s11060-018-2752-5DOI Listing
May 2018

Soluble SLAMF6 Receptor Induces Strong CD8 T-cell Effector Function and Improves Anti-Melanoma Activity .

Cancer Immunol Res 2018 02 5;6(2):127-138. Epub 2018 Jan 5.

Sharett Institute of Oncology, Hadassah Hebrew University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1158/2326-6066.CIR-17-0383DOI Listing
February 2018

Spontaneous Activation of Antigen-presenting Cells by Genes Encoding Truncated Homo-Oligomerizing Derivatives of CD40.

J Immunother 2017 Feb/Mar;40(2):39-50

*Laboratory of Immunology, MIGAL-Galilee Research Institute, Kiryat Shmona †Sharett Institute of Oncology, Hadassah Hebrew University Hospital, Jerusalem ‡Department of Immunology, Weizmann Institute of Science, Rehovot §Tel-Hai College, Upper Galilee, Israel.

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http://dx.doi.org/10.1097/CJI.0000000000000150DOI Listing
January 2018

Treatment inferred from mutations identified using massive parallel sequencing leads to clinical benefit in some heavily pretreated cancer patients.

Medicine (Baltimore) 2017 May;96(20):e6931

aSharett Institute of Oncology bLeslie and Michael Gaffin Center for Oncology, Departments of Oncology and Neurology, Hebrew University-Hadassah Medical Center cDepartment of Pediatrics, Hadassah Medical Center, Division of Pediatric Hematology and Oncology dLautenberg Center for Immunology, IMRIC, The Hebrew University-Hadassah Medical School eDepartment of Pathology, Hebrew University-Hadassah Medical Center, Jerusalem, Israel.

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http://Insights.ovid.com/crossref?an=00005792-201705190-0002
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http://dx.doi.org/10.1097/MD.0000000000006931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440149PMC
May 2017

Adoptive cell therapy: past, present and future.

Immunotherapy 2017 01;9(2):183-196

Sharett Institute of Oncology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.2217/imt-2016-0112DOI Listing
January 2017

Clinical Significance of Circulating CD33+CD11b+HLA-DR- Myeloid Cells in Patients with Stage IV Melanoma Treated with Ipilimumab.

Clin Cancer Res 2016 Dec 13;22(23):5661-5672. Epub 2016 May 13.

Sharett Institute of Oncology, Hadassah Medical Organization, Jerusalem, Israel.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-3104DOI Listing
December 2016

Membrane-attached Cytokines Expressed by mRNA Electroporation Act as Potent T-Cell Adjuvants.

J Immunother 2016 Feb-Mar;39(2):60-70

*Laboratory of Immunology, MIGAL-Galilee Research Institute, Kiryat Shmona †Sharett Institute of Oncology, Hadassah Hebrew University Hospital, Jerusalem ‡Ella Lemelbaum Institute for Melanoma, Sheba Medical Center, Ramat Gan §Department of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel Aviv University, Tel Aviv ∥Tel-Hai College, Upper Galilee, Israel.

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http://dx.doi.org/10.1097/CJI.0000000000000109DOI Listing
November 2016

Immune Monitoring of Patients Treated With a Whole-Cell Melanoma Vaccine Engineered to Express 4-1BBL.

J Immunother 2016 10;39(8):321-8

*Sharett Institute of Oncology, Hadassah Hebrew University Hospital ‡Department of Oncology, Shaare Zedek Medical Center, Jerusalem †Department of Oncology, Tel Aviv Sourasky Medical Center, Tel Aviv §Tumor Immunology and Immunotherapy Lab, Bar Ilan University, Ramat Gan, Israel.

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http://dx.doi.org/10.1097/CJI.0000000000000138DOI Listing
October 2016

Human T cell crosstalk is induced by tumor membrane transfer.

PLoS One 2015 11;10(2):e0118244. Epub 2015 Feb 11.

Sharett Institute of Oncology, Hadassah Medical Organization, P.O. Box 12000, Jerusalem 91120, Israel.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118244PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324967PMC
January 2016

Assessing Response to New Treatments and Prognosis in Melanoma Patients, by the Biomarker S-100β.

Anticancer Res 2015 Dec;35(12):6755-60

Department of Oncology, Hadassah, Hebrew University Medical Center, Jerusalem, Israel.

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December 2015

A new role of vemurafenib as a neoadjuvant treatment of axillary and brain melanoma metastases.

Case Rep Oncol Med 2013 23;2013:794239. Epub 2013 Dec 23.

Department of General and Vascular Surgery, Barzilai Medical Center, Hahistadrut Street 2, 78278 Ashkelon, Israel.

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http://downloads.hindawi.com/journals/crionm/2013/794239.pdf
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http://www.hindawi.com/journals/crionm/2013/794239/
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http://dx.doi.org/10.1155/2013/794239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884783PMC
January 2014

Ocular melanoma metastasizing to intra-abdominal lymph nodes.

Case Rep Surg 2013 16;2013:534730. Epub 2013 May 16.

Department of Surgery, Rabin Medical Center, Beilinson Hospital, 39 Jabotinsky Street, 49100 Petah Tikva, Israel.

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http://downloads.hindawi.com/journals/cris/2013/534730.pdf
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http://www.hindawi.com/journals/cris/2013/534730/
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http://dx.doi.org/10.1155/2013/534730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670551PMC
June 2013

[Ctla-4 blockade: a new hope for the immunotherapy of malignant melanoma].

Harefuah 2012 Oct;151(10):585-8, 604

Sharett Institute of Oncology, Hadassah Hebrew University Hospital, Jerusalem.

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October 2012

Extracellular matrix constituents interfere with Newcastle disease virus spread in solid tissue and diminish its potential oncolytic activity.

J Gen Virol 2012 Aug 23;93(Pt 8):1664-72. Epub 2012 May 23.

Department of Biochemistry, the Chanock Center for Virology, IMRIC, Hadassah Medical Center-Hebrew University, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1099/vir.0.043281-0DOI Listing
August 2012

The clinical effect of the inhibitor of apopotosis protein livin in melanoma.

Oncology 2012 22;82(4):197-204. Epub 2012 Mar 22.

Department of Hematology, Hadassah - Hebrew University Medical Center, Jerusalem, Israel.

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http://dx.doi.org/10.1159/000334234DOI Listing
June 2012

Serum CEACAM1 Correlates with Disease Progression and Survival in Malignant Melanoma Patients.

Clin Dev Immunol 2012 16;2012:290536. Epub 2012 Jan 16.

The Ella Institute for Treatment and Research of Melanoma and Skin Cancer, The Sheba Cancer Research Center, The Chaim Sheba Medical Center, Tel Hashomer 52621, Israel.

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http://dx.doi.org/10.1155/2012/290536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265158PMC
May 2012

Trogocytosis is a gateway to characterize functional diversity in melanoma-specific CD8+ T cell clones.

J Immunol 2012 Jan 7;188(2):632-40. Epub 2011 Dec 7.

Sharett Institute of Oncology, Hadassah Medical Organization, Jerusalem 91120, Israel.

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http://dx.doi.org/10.4049/jimmunol.1101429DOI Listing
January 2012

Autologous melanoma vaccine induces antitumor and self-reactive immune responses that affect patient survival and depend on MHC class II expression on vaccine cells.

Clin Cancer Res 2009 Aug 14;15(15):4968-77. Epub 2009 Jul 14.

Sharett Institute of Oncology and Departments of Surgery, Hadassah Hebrew University Hospital, Ein Karem and Mount Scopus Campuses, Jerusalem, Israel.

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-08-3320DOI Listing
August 2009

Absence of founder BRCA1 and BRCA2 mutations in cutaneous malignant melanoma patients of Ashkenazi origin.

Fam Cancer 2009 5;8(1):29-32. Epub 2008 Aug 5.

Sharett Institute of Oncology, Hebrew University-Hadassah Medical Center, Jerusalem, 91120, Israel.

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http://link.springer.com/10.1007/s10689-008-9206-8
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http://dx.doi.org/10.1007/s10689-008-9206-8DOI Listing
April 2009

Metastatic malignant melanoma involving the parotid lymph node region: a clinicopathologic report of 5 cases.

J Oral Maxillofac Surg 2008 Apr;66(4):809-13

Department of Otolaryngology/Head and Neck Surgery, Hadassah Hebrew University Hospital, Jerusalem, Israel.

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http://dx.doi.org/10.1016/j.joms.2006.10.065DOI Listing
April 2008

Ultraviolet radiation and cutaneous carcinogenesis.

Curr Probl Dermatol 2007 ;35:14-27

Department of Dermatology, Hadassah Medical Center and the Hebrew University, Jerusalem, Israel.

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http://dx.doi.org/10.1159/000106407DOI Listing
September 2007

Viral carcinogenesis in skin cancer.

Curr Probl Dermatol 2007 ;35:39-51

Department of Dermatology, Hadassah Hebrew University Hospital, Jerusalem, Israel.

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https://www.karger.com/Article/FullText/106409
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http://dx.doi.org/10.1159/000106409DOI Listing
September 2007

[Parents' risk perception and analysis of children's injuries scenarios from cold fat removers].

Harefuah 2007 Jul;146(7):523-8, 575, 574

Beterem, The National Center for Children's Safety and Health, University of Haifa.

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July 2007

Protease-activated receptor-1 (hPar1), a survival factor eliciting tumor progression.

Mol Cancer Res 2007 Mar;5(3):229-40

Department of Oncology, Hadassah-Hebrew University Hospital, P.O. Box 12000, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1158/1541-7786.MCR-06-0261DOI Listing
March 2007

Molecular detection of MART-1, tyrosinase and MIA in peripheral blood, lymph nodes and metastatic sites of stage III/IV melanoma patients.

Melanoma Res 2004 Oct;14(5):361-5

Department of Dermatology, Hadassah-Hebrew University Medical Center, P.O. Box 12000, Jerusalem 91120, Israel.

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October 2004

Irrigation of the bile ducts with chilled saline during percutaneous radiofrequency ablation of a hepatic ocular melanoma metastasis.

AJR Am J Roentgenol 2004 Sep;183(3):596-8

Department of Radiology, Hadassah University Hospital, Ein-Kerem, PO Box 12000, Jerusalem 91120, Israel.

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http://dx.doi.org/10.2214/ajr.183.3.1830596DOI Listing
September 2004

An open trial of climatotherapy at the Dead Sea for patch-stage mycosis fungoides.

J Am Acad Dermatol 2004 Jul;51(1):33-8

Department of Dermatology, the Rabin Medical Center, Beilinson Campus, Petah Tikva, Israel.

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http://dx.doi.org/10.1016/j.jaad.2003.11.052DOI Listing
July 2004

Recombinant hydrophilic human gp100: uptake by dendritic cells and stimulation of autologous CD8+ lymphocytes from melanoma patients.

Immunol Lett 2004 Jul;94(3):253-9

Department of Oncology, Hadassah Medical Organization, P.O. Box 12 000, Jerusalem 91 120, Israel.

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http://dx.doi.org/10.1016/j.imlet.2004.05.014DOI Listing
July 2004

Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma.

Cancer Res 2003 Oct;63(19):6340-9

Department of Hematology, Hadassah University Hospital, Ein-Karem, Jerusalem 91120, Israel.

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October 2003

Cytogenetic analysis of melanoma cell lines: subclone selection in long-term melanoma cell cultures.

Cancer Genet Cytogenet 2003 Apr;142(2):87-91

Sharett Institute of Oncology, Hadassah Hebrew University Hospital, Kiryat Hadassah, Jerusalem, Israel.

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http://dx.doi.org/10.1016/s0165-4608(02)00798-7DOI Listing
April 2003

Mucosal melanoma of the female genital tract is a multifocal disorder.

Gynecol Oncol 2003 Jan;88(1):45-50

Sharett Institute of Oncology, Hadassan University Hospital, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1006/gyno.2002.6848DOI Listing
January 2003

CD66a interactions between human melanoma and NK cells: a novel class I MHC-independent inhibitory mechanism of cytotoxicity.

J Immunol 2002 Mar;168(6):2803-10

Lautenberg Center for General and Tumor Immunology and Sharet Institute of Oncology, Hadassah Medical School, Jerusalem, Israel.

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http://dx.doi.org/10.4049/jimmunol.168.6.2803DOI Listing
March 2002